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Wei-Dong Yu
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Journal Articles

Abstract 3434: Inecalcitol, an analogue of 1,25D3, displays enhanced antitumor activity through the induction of apoptosis in a squamous cell carcinoma model system.

Yingyu Ma, Wei-Dong Yu, Alejandro A. Hidalgo, Wei Luo, Remi Delansorne, Candace S. Johnson, Donald L. Trump
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3434.
https://doi.org/10.1158/1538-7445.AM2013-3434
Published: 15 April 2013
View article titled, Abstract 3434: Inecalcitol, an analogue of 1,25D3, displays enhanced antitumor activity through the induction of apoptosis in a squamous cell carcinoma model system.
Journal Articles

Inhibition of Protein Kinase CK2 Reduces Cyp24a1 Expression and Enhances 1,25-Dihydroxyvitamin D3 Antitumor Activity in Human Prostate Cancer Cells

Wei Luo, Wei-Dong Yu, Yingyu Ma, Mikhail Chernov, Donald L. Trump, Candace S. Johnson
Journal: Cancer Research
Cancer Res (2013) 73 (7): 2289–2297.
https://doi.org/10.1158/0008-5472.CAN-12-4119
Published: 02 April 2013
View article titled, Inhibition of Protein Kinase CK2 Reduces <em>Cyp24a1</em> Expression and Enhances 1,25-Dihydroxyvitamin D<sub>3</sub> Antitumor Activity in Human Prostate Cancer Cells
Open the PDF for Inhibition of Protein Kinase CK2 Reduces <em>Cyp24a1</em> Expression and Enhances 1,25-Dihydroxyvitamin D<sub>3</sub> Antitumor Activity in Human Prostate Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 583: Inecalcitol, a 14-epi-analogue of 1,25D3, induces growth inhibition through apoptosis and cell cycle arrest in a squamous cell carcinoma model system

Yingyu Ma, Wei-Dong Yu, Rui-Xian Kong, Remi Delansorne, Donald L. Trump, Candace S. Johnson
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 583.
https://doi.org/10.1158/1538-7445.AM2011-583
Published: 15 April 2011
View article titled, Abstract 583: Inecalcitol, a 14-epi-analogue of 1,25D<sub>3</sub>, induces growth inhibition through apoptosis and cell cycle arrest in a squamous cell carcinoma model system
Journal Articles

Abstract 5123: 1,25D3 regulates cell-matrix and cell-cell adhesion and reduces experimental metastasis in a squamous cell carcinoma model system

Yingyu Ma, Bing Su, Wei-Dong Yu, Mukund Seshadri, Steven G. Turowski, Rui-Xian Kong, Bryan M. Gillard, Donald L. Trump, Candace S. Johnson
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5123.
https://doi.org/10.1158/1538-7445.AM10-5123
Published: 15 April 2010
View article titled, Abstract 5123: 1,25D<sub>3</sub> regulates cell-matrix and cell-cell adhesion and reduces experimental metastasis in a squamous cell carcinoma model system
Journal Articles

Abstract #868: 1,25D3 enhances antitumor effects of cisplatin and gemcitabine in human bladder cancer model systems

Yingyu Ma, Wei-Dong Yu, Rui-Xian Kong, Donald Trump, Candace Johnson
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 868.
Published: 01 May 2009
View article titled, Abstract #868: 1,25D<sub>3</sub> enhances antitumor effects of cisplatin and gemcitabine in human bladder cancer model systems
Journal Articles

Role of Vitamin D Receptor in the Antiproliferative Effects of Calcitriol in Tumor-Derived Endothelial Cells and Tumor Angiogenesis In vivo

Ivy Chung, Guangzhou Han, Mukund Seshadri, Bryan M. Gillard, Wei-dong Yu, Barbara A. Foster, Donald L. Trump, Candace S. Johnson
Journal: Cancer Research
Cancer Res (2009) 69 (3): 967–975.
https://doi.org/10.1158/0008-5472.CAN-08-2307
Published: 29 January 2009
View article titled, Role of Vitamin D Receptor in the Antiproliferative Effects of Calcitriol in Tumor-Derived Endothelial Cells and Tumor Angiogenesis <em>In vivo</em>
Open the PDF for Role of Vitamin D Receptor in the Antiproliferative Effects of Calcitriol in Tumor-Derived Endothelial Cells and Tumor Angiogenesis <em>In vivo</em> in another window
Journal Articles

1,25D3 regulates adhesion, migration and invasion of squamous cell carcinoma cells

Yingyu Ma, Bing Su, Wei-Dong Yu, Rui-Xian Kong, Donald Trump, Candace Johnson
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4574.
Published: 01 May 2008
View article titled, 1,25D<sub>3</sub> regulates adhesion, migration and invasion of squamous cell carcinoma cells
Journal Articles

Calcitriol and taxotere suppress bone metastases in PC-3M-luc-C6 prostate cancer mouse model as monitored by bioluminescence imaging

Wei-Dong Yu, Yingyu Ma, Rui-Xian Kong, Donald Trump, Candace Johnson
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3687.
Published: 01 May 2008
View article titled, Calcitriol and taxotere suppress bone metastases in PC-3M-luc-C6 prostate cancer mouse model as monitored by bioluminescence imaging
Journal Articles

In vivo function of vitamin D receptor (VDR) in tumor angiogenesis

Ivy Chung, Mukund Seshadri, Wei-dong Yu, Mohamed Khan, Donald Trump, Candace Johnson
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4625.
Published: 01 May 2007
View article titled, In vivo function of vitamin D receptor (VDR) in tumor angiogenesis
Journal Articles

1,25D3 potentiates the cytotoxic effects of cisplatin through up-regulation of p73 and enhancement of apoptosis in squamous cell carcinoma cells

Yingyu Ma, Wei-Dong Yu, Geraldine Flynn, Pamela Hershberger, Rui-Xian Kong, Donald Trump, Candace Johnson
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 449.
Published: 01 May 2007
View article titled, 1,25D<sub>3</sub> potentiates the cytotoxic effects of cisplatin through up-regulation of p73 and enhancement of apoptosis in squamous cell carcinoma cells
Journal Articles

19-Nor-1,25(OH)2D2 in conjunction with gemcitabine induces antiproliferative activity through the suppression of 24-hydroxylase activity and the enhancement of apoptosis in a human pancreatic carcinoma cell line

Wei-Dong Yu, Yingyu Ma, Kristie Engler, Rui-Xian Kong, Josephia Muindi, Donald Trump, Candace Johnson
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1911.
Published: 01 May 2007
View article titled, 19-Nor-1,25(OH)<sub>2</sub>D<sub>2 </sub>in conjunction with gemcitabine induces antiproliferative activity through the suppression of 24-hydroxylase activity and the enhancement of apoptosis in a human pancreatic carcinoma cell line
Journal Articles

Differential Antiproliferative Effects of Calcitriol on Tumor-Derived and Matrigel-Derived Endothelial Cells

Ivy Chung, Michael K. Wong, Geraldine Flynn, Wei-dong Yu, Candace S. Johnson, Donald L. Trump
Journal: Cancer Research
Cancer Res (2006) 66 (17): 8565–8573.
https://doi.org/10.1158/0008-5472.CAN-06-0905
Published: 01 September 2006
View article titled, Differential Antiproliferative Effects of Calcitriol on Tumor-Derived and Matrigel-Derived Endothelial Cells
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Journal Articles

Role of Nongenomic Activation of Phosphatidylinositol 3-Kinase/Akt and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase/Extracellular Signal-Regulated Kinase 1/2 Pathways in 1,25D3-Mediated Apoptosis in Squamous Cell Carcinoma Cells

Yingyu Ma, Wei-Dong Yu, Rui-Xian Kong, Donald L. Trump, Candace S. Johnson
Journal: Cancer Research
Cancer Res (2006) 66 (16): 8131–8138.
https://doi.org/10.1158/0008-5472.CAN-06-1333
Published: 15 August 2006
View article titled, Role of Nongenomic Activation of Phosphatidylinositol 3-Kinase/Akt and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase/Extracellular Signal-Regulated Kinase 1/2 Pathways in 1,25D3-Mediated Apoptosis in Squamous Cell Carcinoma Cells
Open the PDF for Role of Nongenomic Activation of Phosphatidylinositol 3-Kinase/Akt and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase/Extracellular Signal-Regulated Kinase 1/2 Pathways in 1,25D3-Mediated Apoptosis in Squamous Cell Carcinoma Cells in another window
Journal Articles

Role of non-genomic activation of PI3K/Akt and MEK/ERK1/2 pathways in 1,25D3-mediated apoptosis in SCC cells

Yingyu Ma, Wei-Dong Yu, Rui-Xian Kong, Donald L. Trump, Candace S. Johnson
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 172.
Published: 15 April 2006
View article titled, Role of non-genomic activation of PI3K/Akt and MEK/ERK1/2 pathways in 1,25D<sub>3</sub>-mediated apoptosis in SCC cells
Journal Articles

Activation of a mitochondrial apoptosis pathway induced by calcitriol in combination with ketoconazole and dexamethasone in human prostate cancer PC-3 cells

Wei-Dong Yu, Yingyu Ma, Rui-xian Kong, Donald L. Trump, Candace S. Johnson
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 952.
Published: 15 April 2006
View article titled, Activation of a mitochondrial apoptosis pathway induced by calcitriol in combination with ketoconazole and dexamethasone in human prostate cancer PC-3 cells
Journal Articles

Inhibitors of 24-hydroxylase activity enhance systemic calcitriol exposure in preclinical animal models

Josephia R. Muindi, Wei Dong Yu, Kristie Engler, Candace S. Johnson, Donald L. Trump
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 508–509.
Published: 15 April 2006
View article titled, Inhibitors of 24-hydroxylase activity enhance systemic calcitriol exposure in preclinical animal models
Journal Articles

The in vitro and in vivo effect of 1,25-dihydroxycholecalciferol (calcitriol) on tumor-derived endothelial cell (TDEC) and matrigel-derived endothelial cell (MDEC)

Ivy Chung, Geraldine Flynn, Wei-Dong Yu, Michael K. Wong, Candace S. Johnson, Donald L. Trump
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 477.
Published: 01 May 2005
View article titled, The <em>in vitro</em> and <em>in vivo</em> effect of 1,25-dihydroxycholecalciferol (calcitriol) on tumor-derived endothelial cell (TDEC) and matrigel-derived endothelial cell (MDEC)
Journal Articles

Effect of ketoconazole with dexamethasone on 1,25-dihydroxycholecalciferol mediated anti-tumor activity in vitro and in vivo in the human prostate cancer PC-3 model; association with increased caspase-8 cleavage and apoptosis

Wei-Dong Yu, Pamela A. Hershberger, Yiu-Keung Lau, Josephia Muindi, Rui-Xian Kong, Donald L. Trump, Candace S. Johnson
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1261–1262.
Published: 01 May 2005
View article titled, Effect of ketoconazole with dexamethasone on 1,25-dihydroxycholecalciferol mediated anti-tumor activity <em>in vitro</em> and <em>in vivo</em> in the human prostate cancer PC-3 model; association with increased caspase-8 cleavage and apoptosis
Journal Articles

Calcitriol enhances gemcitabine anti-tumor activity in vitro and in vivo in a human pancreatic carcinoma model in association with increased apotosis and decreased P-Akt.

Wei-Dong Yu, Pamela A. Hershberger, Josephia Muindi, Ralph Fuller, Rui-Xian Kong, Donald L. Trump, Candace S. Johnson
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 507.
Published: 01 April 2004
View article titled, Calcitriol enhances gemcitabine anti-tumor activity <em>in vitro</em> and <em>in vivo</em> in a human pancreatic carcinoma model in association with increased apotosis and decreased P-Akt.
Journal Articles

Potentiation of Cisplatin Antitumor Activity Using a Vitamin D Analogue in a Murine Squamous Cell Carcinoma Model System

Benjamin W. Light, Wei-Dong Yu, Mariann C. McElwain, Derrick M. Russell, Donald L. Trump, Candace S. Johnson
Journal: Cancer Research
Cancer Res (1997) 57 (17): 3759–3764.
Published: 01 September 1997
View article titled, Potentiation of Cisplatin Antitumor Activity Using a Vitamin D Analogue in a Murine Squamous Cell Carcinoma Model System
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