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Journal Articles

Engineered SH3-Derived Sherpabodies Function as a Modular Platform for Targeted T-cell Immunotherapy

Rogelio A. Hernández-López, Tapio Kesti, Anna R. Mäkelä, Zhe Zhao, Wei Yu, Yurie Tonai, Hector J. Monzo, Kerttu Kalander, Sirpa Leppä, Päivi M. Ojala, Wendell A. Lim, Kalle Saksela

Cancer Res (2025) 85 (10): 1874–1887.

https://doi.org/10.1158/0008-5472.CAN-24-1959

Published: 15 May 2025

View articletitled, Engineered SH3-Derived Sherpabodies Function as a Modular Platform for Targeted T-cell Immunotherapy

Includes: Supplementary data

Journal Articles

Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression

Lingling Li, Dongxian Jiang, Hui Liu, Chunmei Guo, Qiao Zhang, Xuedong Li, Xiaojian Chen, Zheqi Chen, Jinwen Feng, Subei Tan, Wen Huang, Jie Huang, Chen Xu, Chen-Ying Liu, Wei Yu, Yingyong Hou, Chen Ding

Cancer Res (2024) 84 (17): 2888–2910.

https://doi.org/10.1158/0008-5472.CAN-23-1878

Published: 04 September 2024

View articletitled, Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression

Includes: Supplementary data

Journal Articles

Abstract 161: Aged mice decelerate bone metastasis of prostate cancer by decreasing infiltration of M2 macrophages

Xiao Zhang, Wei Yu, Xin Huang, Yi Lu, Jian Zhang

Cancer Res (2024) 84 (6_Supplement): 161.

https://doi.org/10.1158/1538-7445.AM2024-161

Published: 22 March 2024

View articletitled, Abstract 161: Aged mice decelerate bone metastasis of prostate cancer by decreasing infiltration of M2 macrophages

Journal Articles

Abstract CT150: Result of an open-label phase 2 trial of dual TORC1/TORC2 inhibitor onatasertib (ATG-008) in HBV+ advanced hepatocellular carcinoma (HCC) subjects who have received at least one prior line of systemic therapy (TORCH)

Cancer Res (2023) 83 (8_Supplement): CT150.

https://doi.org/10.1158/1538-7445.AM2023-CT150

Published: 14 April 2023

View articletitled, Abstract CT150: Result of an open-label phase 2 trial of dual TORC1/TORC2 inhibitor onatasertib (ATG-008) in HBV+ advanced hepatocellular carcinoma (HCC) subjects who have received at least one prior line of systemic therapy (TORCH)

Journal Articles

Abstract 6702: The clinical characteristics and outcomes of NSCLC patients with genomic alterations detected by blood-based NGS ctDNA assay

Hsin-Yi Wang, Chao-Chi Ho, Yen-Ting Lin, Wei-Yu Liao, Chung-Yu Chen, Jin-Yuan Shih, Chong-Jen Yu

Cancer Res (2023) 83 (7_Supplement): 6702.

https://doi.org/10.1158/1538-7445.AM2023-6702

Published: 04 April 2023

View articletitled, Abstract 6702: The clinical characteristics and outcomes of NSCLC patients with genomic alterations detected by blood-based NGS ctDNA assay

Journal Articles

Abstract 3514: A genetic-metabolic circuit of liver-specific metastatic organotropism

Cancer Res (2023) 83 (7_Supplement): 3514.

https://doi.org/10.1158/1538-7445.AM2023-3514

Published: 04 April 2023

View articletitled, Abstract 3514: A genetic-metabolic circuit of liver-specific metastatic organotropism

Journal Articles

Abstract 3062: ROMO1 mediates mitochondrial function links to neuroendocrine differentiation of prostate cancer enhancement by the nuclear PKLR/MYCN/MAX complex

Yen-Nien Liu, Wei-Yu Chen, Phan Vu Thuy Dung, Hsiu-Lien Yeh, Zi-Qing Chen, Wan-Hsin Wang, Yu-Ching Wen

Cancer Res (2023) 83 (7_Supplement): 3062.

https://doi.org/10.1158/1538-7445.AM2023-3062

Published: 04 April 2023

View articletitled, Abstract 3062: ROMO1 mediates mitochondrial function links to neuroendocrine differentiation of prostate cancer enhancement by the nuclear PKLR/MYCN/MAX complex

Journal Articles

Abstract 3736: ZBTB46/FOXA2/HIF1A transcription activator complex promotes MCTP1-regulated neuroendocrine differentiation and epithelial-to-mesenchymal transition

Vu Thuy Dung Phan, Yu-Ching Wen, Wei-Yu Chen, Wei-Hao Chen, Kuo-Ching Jiang, Han-Ru Li, Van Thi Ngoc Tram, Zi-Qing Chen, Wan-Hsin Wang, Yen-Nien Liu

Cancer Res (2023) 83 (7_Supplement): 3736.

https://doi.org/10.1158/1538-7445.AM2023-3736

Published: 04 April 2023

View articletitled, Abstract 3736: ZBTB46/FOXA2/HIF1A transcription activator complex promotes MCTP1-regulated neuroendocrine differentiation and epithelial-to-mesenchymal transition

Journal Articles

Anti-HIV Drug Elvitegravir Suppresses Cancer Metastasis via Increased Proteasomal Degradation of m⁶A Methyltransferase METTL3

Long Liao, Yan He, Shu-Jun Li, Guo-Geng Zhang, Wei Yu, Jing Yang, Zi-Jia Huang, Can-Can Zheng, Qing-Yu He, Yan Li, Bin Li

Cancer Res (2022) 82 (13): 2444–2457.

https://doi.org/10.1158/0008-5472.CAN-21-4124

Published: 05 July 2022

View articletitled, Anti-HIV Drug Elvitegravir Suppresses Cancer Metastasis via Increased Proteasomal Degradation of m6A Methyltransferase METTL3

Includes: Supplementary data

Journal Articles

Abstract 4752: Exon-16-skipping HER2 contributes to osimertinib-resistance through Src-independent manner in EGFRL858R/T790M-positive non-small-cell lung cancer

Chia-Chi Hsu, Bin-Chi Liao, Wei-Yu Liao, Aleksandra Markovets, Daniel Stetson, Kenneth Thress, Chih-Hsin Yang

Cancer Res (2019) 79 (13_Supplement): 4752.

https://doi.org/10.1158/1538-7445.AM2019-4752

Published: 01 July 2019

View articletitled, Abstract 4752: Exon-16-skipping HER2 contributes to osimertinib-resistance through Src-independent manner in EGFRL858R/T790M-positive non-small-cell lung cancer

Journal Articles

Abstract A031: Androgen deprivation therapy-induced TGFBI signaling promotes EMT and bone metastasis of prostate cancer

Yen-Nien Liu, Wei-Yu Chen, Yuan-Chin Tsai, Hsiu-Lien Yeh, Florent Suau, Jiaoti Huang

Cancer Res (2018) 78 (16_Supplement): A031.

https://doi.org/10.1158/1538-7445.PRCA2017-A031

Published: 14 August 2018

View articletitled, Abstract A031: Androgen deprivation therapy-induced TGFBI signaling promotes EMT and bone metastasis of prostate cancer

Journal Articles

Abstract 4509: SATB2/β-catenin/TCF-LEF pathway induces cellular transformation by generating cancer stem cells in colorectal cancer

Yiming Ma, Wei Yu, Sharmila Shankar, Rakesh K. Srivastava

Cancer Res (2018) 78 (13_Supplement): 4509.

https://doi.org/10.1158/1538-7445.AM2018-4509

Published: 01 July 2018

View articletitled, Abstract 4509: SATB2/β-catenin/TCF-LEF pathway induces cellular transformation by generating cancer stem cells in colorectal cancer

Journal Articles

Abstract 3728: α-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis by targeting cancer stem cells in KC and KPC mice

Raj K. Verma, Wei Yu, Anju Shrivastava, Rakesh K. Srivastava, Sharmila Shankar

Cancer Res (2018) 78 (13_Supplement): 3728.

https://doi.org/10.1158/1538-7445.AM2018-3728

Published: 01 July 2018

View articletitled, Abstract 3728: α-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis by targeting cancer stem cells in KC and KPC mice

Journal Articles

Abstract 4467: ETV6 is a tumor suppressor regulated by EGFR-miR-96 pathway in prostate cancer

Yen-Nien Liu, Yuan-Chin Tsai, Wei-Yu Chen, Man Kit Siu, Hsiu-Lien Yeh

Cancer Res (2017) 77 (13_Supplement): 4467.

https://doi.org/10.1158/1538-7445.AM2017-4467

Published: 01 July 2017

View articletitled, Abstract 4467: ETV6 is a tumor suppressor regulated by EGFR-miR-96 pathway in prostate cancer

Journal Articles

Abstract 4065: Mechanistic role of heavy metal cadmium exposure in the etiology of pancreatic cancer

Wei Yu, Yiming Ma, Rakesh Srivastava, Sharmila Shankar

Cancer Res (2016) 76 (14_Supplement): 4065.

https://doi.org/10.1158/1538-7445.AM2016-4065

Published: 15 July 2016

View articletitled, Abstract 4065: Mechanistic role of heavy metal cadmium exposure in the etiology of pancreatic cancer

Journal Articles

Abstract 2074: Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic cancer stem cell characteristics by suppressing sonic hedgehog pathway

Wei Yu, Yiming Ma, Sharmila Shankar, Rakesh K. Srivastava

Cancer Res (2016) 76 (14_Supplement): 2074.

https://doi.org/10.1158/1538-7445.AM2016-2074

Published: 15 July 2016

View articletitled, Abstract 2074: Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic cancer stem cell characteristics by suppressing sonic hedgehog pathway

Journal Articles

Abstract LB-316: Social isolation alters abdominal and mammary adipocytes to potentially increase mammary tumorigenesis in mice

Madisa Macon, Allison Sumis, Wei Yu, Leena Hilakivi-Clarke

Cancer Res (2016) 76 (14_Supplement): LB-316.

https://doi.org/10.1158/1538-7445.AM2016-LB-316

Published: 15 July 2016

View articletitled, Abstract LB-316: Social isolation alters abdominal and mammary adipocytes to potentially increase mammary tumorigenesis in mice

Journal Articles

Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus

Cancer Res (2016) 76 (7): 1916–1925.

https://doi.org/10.1158/0008-5472.CAN-15-1629

Published: 31 March 2016

View articletitled, Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus

Includes: Supplementary data

Journal Articles

EGF Receptor Promotes Prostate Cancer Bone Metastasis by Downregulating miR-1 and Activating TWIST1

Yung-Sheng Chang, Wei-Yu Chen, Juan Juan Yin, Heather Sheppard-Tillman, Jiaoti Huang, Yen-Nien Liu

Cancer Res (2015) 75 (15): 3077–3086.

https://doi.org/10.1158/0008-5472.CAN-14-3380

Published: 02 August 2015

View articletitled, EGF Receptor Promotes Prostate Cancer Bone Metastasis by Downregulating miR-1 and Activating TWIST1

Includes: Supplementary data

Journal Articles

Abstract A121: Suppression of orthotopic pancreatic cancer growth by sulforaphane is associated with activation of FOXO transcription factors

Wei Yu, Rakesh Srivastava, Sharmila Shankar

Cancer Res (2015) 75 (13_Supplement): A121.

https://doi.org/10.1158/1538-7445.PANCA2014-A121

Published: 30 June 2015

View articletitled, Abstract A121: Suppression of orthotopic pancreatic cancer growth by sulforaphane is associated with activation of FOXO transcription factors

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Engineered SH3-Derived Sherpabodies Function as a Modular Platform for Targeted T-cell Immunotherapy

Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression

Abstract 161: Aged mice decelerate bone metastasis of prostate cancer by decreasing infiltration of M2 macrophages

Abstract CT150: Result of an open-label phase 2 trial of dual TORC1/TORC2 inhibitor onatasertib (ATG-008) in HBV+ advanced hepatocellular carcinoma (HCC) subjects who have received at least one prior line of systemic therapy (TORCH)

Abstract 6702: The clinical characteristics and outcomes of NSCLC patients with genomic alterations detected by blood-based NGS ctDNA assay

Abstract 3514: A genetic-metabolic circuit of liver-specific metastatic organotropism

Abstract 3062: ROMO1 mediates mitochondrial function links to neuroendocrine differentiation of prostate cancer enhancement by the nuclear PKLR/MYCN/MAX complex

Abstract 3736: ZBTB46/FOXA2/HIF1A transcription activator complex promotes MCTP1-regulated neuroendocrine differentiation and epithelial-to-mesenchymal transition

Anti-HIV Drug Elvitegravir Suppresses Cancer Metastasis via Increased Proteasomal Degradation of m⁶A Methyltransferase METTL3

Abstract 4752: Exon-16-skipping HER2 contributes to osimertinib-resistance through Src-independent manner in EGFRL858R/T790M-positive non-small-cell lung cancer

Abstract A031: Androgen deprivation therapy-induced TGFBI signaling promotes EMT and bone metastasis of prostate cancer

Abstract 4509: SATB2/β-catenin/TCF-LEF pathway induces cellular transformation by generating cancer stem cells in colorectal cancer

Abstract 3728: α-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis by targeting cancer stem cells in KC and KPC mice

Abstract 4467: ETV6 is a tumor suppressor regulated by EGFR-miR-96 pathway in prostate cancer

Abstract 4065: Mechanistic role of heavy metal cadmium exposure in the etiology of pancreatic cancer

Abstract 2074: Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic cancer stem cell characteristics by suppressing sonic hedgehog pathway

Abstract LB-316: Social isolation alters abdominal and mammary adipocytes to potentially increase mammary tumorigenesis in mice

Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus

EGF Receptor Promotes Prostate Cancer Bone Metastasis by Downregulating miR-1 and Activating TWIST1

Abstract A121: Suppression of orthotopic pancreatic cancer growth by sulforaphane is associated with activation of FOXO transcription factors

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