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Journal Articles

Targeting WNT/β-Catenin via Modulating EZH2 Function: A New Chapter in the Treatment of β-Catenin Mutant Hepatocellular Carcinoma?

Man Hsin Hung, Xin Wei Wang
Journal: Cancer Research
Cancer Res (2023) 83 (21): 3498–3500.
https://doi.org/10.1158/0008-5472.CAN-23-2921
Published: 01 November 2023
View article titled, Targeting WNT/β-Catenin via Modulating EZH2 Function: A New Chapter in the Treatment of β-Catenin Mutant Hepatocellular Carcinoma?
Open the PDF for Targeting WNT/β-Catenin via Modulating EZH2 Function: A New Chapter in the Treatment of β-Catenin Mutant Hepatocellular Carcinoma? in another window
Journal Articles

Abstract 4134: Boosting anti-tumor immunity by promoting high endothelial venule and tertiary lymphoid structure formation in solid tumors via LTBR agonism

Disi An, Guoying Chen, Wei Wang, Katja Mohrs, David DiLillo, Christopher Daly, Gavin Thurston, John Lin, Namita Gupta, Mickey Atwal, Frank Kuhnert
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4134.
https://doi.org/10.1158/1538-7445.AM2023-4134
Published: 04 April 2023
View article titled, Abstract 4134: Boosting anti-tumor immunity by promoting high endothelial venule and tertiary lymphoid structure formation in solid tumors via LTBR agonism
Journal Articles

Abstract 620: Regulation of anti-tumor immune response by EphA2 receptor tyrosine kinase

Roger Xiaojun Shi, Ryan Lingerak, So-Yeon Kim, Wei Wang, Khalid Sossey-Alaoui, Bingcheng Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 620.
https://doi.org/10.1158/1538-7445.AM2023-620
Published: 04 April 2023
View article titled, Abstract 620: Regulation of anti-tumor immune response by EphA2 receptor tyrosine kinase
Journal Articles

Abstract 1404: A functional genetic polymorphism of mitochondrion-associated DNAJA3 in nonalcoholic steatohepatitis-related hepatocellular carcinoma

Yuto Shiode, Ching-Wen Chang, Xin Wei Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1404.
https://doi.org/10.1158/1538-7445.AM2023-1404
Published: 04 April 2023
View article titled, Abstract 1404: A functional genetic polymorphism of mitochondrion-associated DNAJA3 in nonalcoholic steatohepatitis-related hepatocellular carcinoma
Journal Articles

Abstract 6611: Harnessing the power of multiomics from a single sample to explore tumor heterogeneity and advancing immuno-oncology research

Bhagyashree S. Birla, Andrea O'Hara, Elizabeth Louie, Ben Niu, Haythem Latif, Vanessa Tumilasci, Yang Han, Yongjun Fan, David Corney, Pranay Vishwanath, Wei Wang, Alfredo Staffa, Ilaria DeVito, Laure Turner, Chris Mozdzierz, Peter Nowacki, Ginger Zhou
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6611.
https://doi.org/10.1158/1538-7445.AM2023-6611
Published: 04 April 2023
View article titled, Abstract 6611: Harnessing the power of multiomics from a single sample to explore tumor heterogeneity and advancing immuno-oncology research
Journal Articles

Abstract 2293: Tumor-informed fixed and patient-specific panels for minimal residual disease (MRD) detection in early-stage NSCLC:a head-to-head comparison

Pengpeng Zhang, Zetian Gong, Yue Yu, Xiaoxuan Wang, Lei Ye, Xiaoqiang Wang, Xuan Tang, Chao Zhang, Wanglong Deng, Chao Song, Qing Xu, Yansong Li, Wei Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2293.
https://doi.org/10.1158/1538-7445.AM2023-2293
Published: 04 April 2023
View article titled, Abstract 2293: Tumor-informed fixed and patient-specific panels for minimal residual disease (MRD) detection in early-stage NSCLC:a head-to-head comparison
Journal Articles

Abstract 3914: BTK and MALT1 are critical for cell adhesion and dissemination in mantle cell lymphoma

Vivian Changying Jiang, Yang Liu, Qingsong Cai, Joseph M. McIntosh, Yijing Li, Zhihong Chen, Heng-Huan Lee, Wei Wang, Yixin Yao, Lei Nie, Michael Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3914.
https://doi.org/10.1158/1538-7445.AM2023-3914
Published: 04 April 2023
View article titled, Abstract 3914: BTK and MALT1 are critical for cell adhesion and dissemination in mantle cell lymphoma
Journal Articles

Abstract 6304: Preclinical development of a next generation antibody drug conjugate (ADC) targeting B7-H3 for treatment of solid tumors

Jian Xu, Qing Zong, Wei Wang, Qigang Liu, Sasha Stann, Jiaqiang Cai
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6304.
https://doi.org/10.1158/1538-7445.AM2023-6304
Published: 04 April 2023
View article titled, Abstract 6304: Preclinical development of a next generation antibody drug conjugate (ADC) targeting B7-H3 for treatment of solid tumors
Journal Articles

Abstract 3683: Activation of purine anabolism creates a therapeutic vulnerability in hepatocellular carcinoma via m6A-mediated epitranscriptomic regulation

Man-Hsin Hung, Ching Wen Chang, Kathy Cheng Wang, Jittiporn Chaisaingmongkol, Mathuros Ruchirawat, Tim F. Greten, Xin Wei Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3683.
https://doi.org/10.1158/1538-7445.AM2023-3683
Published: 04 April 2023
View article titled, Abstract 3683: Activation of purine anabolism creates a therapeutic vulnerability in hepatocellular carcinoma via m6A-mediated epitranscriptomic regulation
Journal Articles

Abstract 2786: Targeting oncogene and inflammation for cancer therapy

Wei Wang, Sayantap Datta, Sadanandan E. Velu, Ming Luo, Ruiwen Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2786.
https://doi.org/10.1158/1538-7445.AM2023-2786
Published: 04 April 2023
View article titled, Abstract 2786: Targeting oncogene and inflammation for cancer therapy
Journal Articles

Long-Chain Acylcarnitines Induce Senescence of Invariant Natural Killer T Cells in Hepatocellular Carcinoma

Xue Cheng, Xiaosheng Tan, Wei Wang, Ziyao Zhang, Rongfei Zhu, Mi Wu, Mingyu Li, Yiqing Chen, Zhihui Liang, Peng Zhu, Xiongwen Wu, Xiufang Weng
Journal: Cancer Research
Cancer Res (2023) 83 (4): 582–594.
https://doi.org/10.1158/0008-5472.CAN-22-2273
Published: 15 February 2023
View article titled, Long-Chain Acylcarnitines Induce Senescence of Invariant Natural Killer T Cells in Hepatocellular Carcinoma
Open the PDF for Long-Chain Acylcarnitines Induce Senescence of Invariant Natural Killer T Cells in Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 671: Cryo-electronmicroscopy of PI3K reveals additional regulatory features

Jonathan R. Hart, Su Yang, Xiao Liu, Yingna Xu, Xinyu Zou, Huibing Zhang, Qingtong Zhou, Tian Xia, Yan Zhang, Dehua Yang, Ming-Wei Wang, Peter K. Vogt
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 671.
https://doi.org/10.1158/1538-7445.AM2022-671
Published: 15 June 2022
View article titled, Abstract 671: Cryo-electronmicroscopy of PI3K reveals additional regulatory features
Journal Articles

Abstract 6268: Discovery and characterization of the CD96 antibody GSK6097608, a high-affinity, antagonistic anti-CD96 antibody for cancer immunotherapy

Yan Degenhardt, Jun Guan, Peter Morley, David Jones, Michael Conner, Stephen Eastman, Wei Wang, Andrew Sanderson, Anand Ravindran, Julie Krueger, Iris Roth, James Smothers, Jeremy D. Waight
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6268.
https://doi.org/10.1158/1538-7445.AM2022-6268
Published: 15 June 2022
View article titled, Abstract 6268: Discovery and characterization of the CD96 antibody GSK6097608, a high-affinity, antagonistic anti-CD96 antibody for cancer immunotherapy
Journal Articles

Abstract CT222: Pembrolizumab (pembro) for previously treated advanced hepatocellular carcinoma (aHCC): Meta-analysis of the phase 3 KEYNOTE-240 and KEYNOTE-394 studies

Richard S. Finn, Kangsheng Gu, Xi Chen, Philippe Merle, Kyung-Hun Lee, Mohamed Bouattour, Peiguo Cao, Wei Wang, Ann-Lii Cheng, Liangjun Zhu, Ho Yeong Lim, Masatoshi Kudo, Yueyin Pan, Ting-Tsung Chang, Julien Edeline, Wei Li, Ping Yang, Chen Li, Jianfeng Li, Abby B. Siegel, Shukui Qin
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT222.
https://doi.org/10.1158/1538-7445.AM2022-CT222
Published: 15 June 2022
View article titled, Abstract CT222: Pembrolizumab (pembro) for previously treated advanced hepatocellular carcinoma (aHCC): Meta-analysis of the phase 3 KEYNOTE-240 and KEYNOTE-394 studies
Journal Articles

Abstract 5986: WAVE2/EGF signaling and miR29 regulates WAVE2 to promote tumor growth and metastasis in triple negative breast cancer

Priyanka S. Rana, Wei Wang, Akram Alkrekshi, Vesna Markovic, Khalid Sossey-Alaoui
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5986.
https://doi.org/10.1158/1538-7445.AM2022-5986
Published: 15 June 2022
View article titled, Abstract 5986: WAVE2/EGF signaling and miR29 regulates WAVE2 to promote tumor growth and metastasis in triple negative breast cancer
Journal Articles

Abstract 1994: Defining tumor infiltrating myeloid microenvironment landscapes in HPV+ and HPV- head and neck cancers

Athena E. Golfinos, Wei Wang, Aisha Mergaert, Paul F. Lambert, Huy Q. Dinh
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1994.
https://doi.org/10.1158/1538-7445.AM2022-1994
Published: 15 June 2022
View article titled, Abstract 1994: Defining tumor infiltrating myeloid microenvironment landscapes in HPV+ and HPV- head and neck cancers
Journal Articles

Abstract 5346: WAVE3 phosphorylation promotes chemoresistance and cancer stemness in triple negative breast cancer through downstream of β-catenin oncogenic signaling

Wei Wang, Priyanka Rana, Akram Alkrekshi, Vesna Markovic, Khalid Sossey-Alaoui
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5346.
https://doi.org/10.1158/1538-7445.AM2022-5346
Published: 15 June 2022
View article titled, Abstract 5346: WAVE3 phosphorylation promotes chemoresistance and cancer stemness in triple negative breast cancer through downstream of β-catenin oncogenic signaling
Journal Articles

Abstract 5133: Genetic characteristics & clonal evolution of Chinese resectable colorectal cancer patients with lung metastases

Yong Cheng, Ming-Jian Ge, Peng Dong, Yan-Yu Qiu, Xin-Peng Shu, Jin-Dou Li, Jun-Wei Wang, Xiao-Fang Qi
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5133.
https://doi.org/10.1158/1538-7445.AM2022-5133
Published: 15 June 2022
View article titled, Abstract 5133: Genetic characteristics & clonal evolution of Chinese resectable colorectal cancer patients with lung metastases
Journal Articles

Abstract 5126: PIANOS: A platform independent and normalization free single-sample classifier for colorectal cancer

Du Cai, Haoning Qi, Wei Wang, Min-Er Zhong, Dejun Fan, Cheng-Hang Li, Xiaojian Wu, Feng Gao
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5126.
https://doi.org/10.1158/1538-7445.AM2022-5126
Published: 15 June 2022
View article titled, Abstract 5126: PIANOS: A platform independent and normalization free single-sample classifier for colorectal cancer
Journal Articles

Abstract 5087: KDR mutation as novel biomarker for immune checkpoint inhibitors in pan-cancer

Renhua Guo, Yanan Cui, Pengpeng Zhang, Xiao Liang, Jiali Xu, Xinyin Liu, Yuemin Wu, Wei Wang, Fang Zhang, Junling Zhang, Mengli Huang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5087.
https://doi.org/10.1158/1538-7445.AM2022-5087
Published: 15 June 2022
View article titled, Abstract 5087: <em>KDR</em> mutation as novel biomarker for immune checkpoint inhibitors in pan-cancer