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Journal Articles

Abstract CT009: SHR-A1811, a HER2-directed antibody-drug conjugate (ADC), in advanced HER2-mutant non-small cell lung cancer (NSCLC): Updated phase 2 results from HORIZON-Lung

Free
Shun Lu, Ziming Li, Yan Wang, Yuping Sun, Linlin Wang, Xingya Li, Longhua Sun, Zhiyi He, Haiyan Yang, Yongsheng Wang, Qiming Wang, Zhengbo Song, Wei Hong, Yong Wang, Guohao Xia, Yan Yu, Min Peng, Yong Song, Donglin Wang, Rui Meng, Jian Fang, Yongzhong Luo, Wenhua Liang, Sheng Hu, Zhihui Wang, Haichuan Su, Zhiyong He, Liuning Li, Wei Guo, Zhentian Liu, Qitao Yu, Yun Zhao, Runxiang Yang, Peng Chen, Yiru Wang, You Li, Lulu Yang, Wei Shi
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_2): CT009.
https://doi.org/10.1158/1538-7445.AM2025-CT009
Published: 25 April 2025
View articletitled, Abstract CT009: SHR-A1811, a HER2-directed antibody-drug conjugate (ADC), in advanced HER2-mutant non-small cell lung cancer (NSCLC): Updated phase 2 results from HORIZON-Lung
Journal Articles

Abstract 6326: A comparative study of C3H and C57Bl/6 murine models of radiation-induced fibrosis

Free
Pierre-Antoine Bissey, Justin Williams, Wei Shi, Madison Hossack, Ken W. Yip, Fei-Fei Liu
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6326.
https://doi.org/10.1158/1538-7445.AM2025-6326
Published: 21 April 2025
View articletitled, Abstract 6326: A comparative study of C3H and C57Bl/6 murine models of radiation-induced fibrosis
Journal Articles

Abstract 6367: CHD1 loss hijacks SREBP2-mediated cholesterol biosynthesis to fuel SPOP-deficient prostate cancer and confers resistance to castration

Free
Feiyu Chen, Haoyan Li, Yin Wang, Ximing Tang, Kevin Lin, Qidong Li, Chenling Meng, Wei Shi, Javier Leo, Xin Liang, Jie Zhang, Vivien Van, Iqbal Mahmud, Bo Wei, Philip L. Lorenzi, Maria G. Raso, Ana Aparicio, Yue Lu, Daniel E. Frigo, Boyi Gan, Di Zhao
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6367.
https://doi.org/10.1158/1538-7445.AM2025-6367
Published: 21 April 2025
View articletitled, Abstract 6367: CHD1 loss hijacks SREBP2-mediated cholesterol biosynthesis to fuel SPOP-deficient prostate cancer and confers resistance to castration
Journal Articles

Abstract 4687: Clonal hematopoiesis of indeterminate potential may protect against radiation-induced toxicities in breast cancer patients

Free
Tirthankar Ray, Madison Hossack, Pierre-Antoine Bissey, Justin Williams, Wei Shi, Sagi Abelson, Steven Chan, Kenneth W. Yip, Fei-Fei Liu
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4687.
https://doi.org/10.1158/1538-7445.AM2025-4687
Published: 21 April 2025
View articletitled, Abstract 4687: Clonal hematopoiesis of indeterminate potential may protect against radiation-induced toxicities in breast cancer patients
Journal Articles

Abstract 400: Preclinical development of TQB3019: A potent and selective oral BTK degrader leveraging the OAPD® platform to overcome acquired resistance mutations

Free
Jing Ren, Jinan Wang, Sheng Xu, Jin Liu, Ying Zhang, Xiaojin Wang, Baomin Liu, Wei Shi, Hongjiang Xu, Ling Yang, Wei Zhao, Xiquan Zhang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 400.
https://doi.org/10.1158/1538-7445.AM2025-400
Published: 21 April 2025
View articletitled, Abstract 400: Preclinical development of TQB3019: A potent and selective oral BTK degrader leveraging the OAPD® platform to overcome acquired resistance mutations
Journal Articles

Abstract 2698: TCF-1 is a critical regulator of intraepithelial lymphocytes in colorectal carcinoma

Free
Marina H. Yakou, Sonia Ghilas, Kelly Tran, Yang Liao, Shoukat Afshar-Sterle, Anita Kumari, Kevin Schmid, Christine Dijkstra, Chantelle Inguanti, Simone Ostrouska, Jordan Wilcox, Maxine Smith, Pavitha Parathan, Amr Allam, Hai-Hui Xue, Gabrielle T. Belz, John M. Mariadason, Andreas Behren, Grant R. Drummond, Roland Ruscher, David S. Williams, Bhupinder Pal, Wei Shi, Matthias Ernst, Dinesh Raghu, Lisa A. Mielke
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2698.
https://doi.org/10.1158/1538-7445.AM2024-2698
Published: 22 March 2024
View articletitled, Abstract 2698: TCF-1 is a critical regulator of intraepithelial lymphocytes in colorectal carcinoma
Journal Articles

Abstract 6383: Targeting radiation-induced fibrosis: Exploring promising therapeutic avenues and innovative assessment methods

Free
Pierre-Antoine Bissey, Leonardo Massignan, Ross Mancini, Wei Shi, Justin Williams, Mark Reed, Kenneth W. Yip, Fei-Fei Liu
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6383.
https://doi.org/10.1158/1538-7445.AM2024-6383
Published: 22 March 2024
View articletitled, Abstract 6383: Targeting radiation-induced fibrosis: Exploring promising therapeutic avenues and innovative assessment methods
Journal Articles

Abstract B040: Novel immunotherapy strategies targeting PTEN and TP53 defects in advanced prostate cancer

Free
Wei Shi, Yin Wang, Yuehui Zhao, Di Zhao
Journal: Cancer Research
Cancer Res (2023) 83 (11_Supplement): B040.
https://doi.org/10.1158/1538-7445.PRCA2023-B040
Published: 02 June 2023
View articletitled, Abstract B040: Novel immunotherapy strategies targeting PTEN and TP53 defects in advanced prostate cancer
Journal Articles

Abstract PR007: Intestinal intraepithelial T cells limit colorectal cancer progression

Free
Sonia Ghilas, Dinesh Raghu, Kelly Tran, Yang Liao, Bhupinder Pal, Shoukat Sterle, Christine Dijkstra, Marina Yakou, Pavitha Parathan, John Mariadason, Matthias Ernst, Andreas Behren, Grant Drummond, Wei Shi, Lisa A. Mielke
Journal: Cancer Research
Cancer Res (2022) 82 (23_Supplement_1): PR007.
https://doi.org/10.1158/1538-7445.CRC22-PR007
Published: 01 December 2022
View articletitled, Abstract PR007: Intestinal intraepithelial T cells limit colorectal cancer progression
Journal Articles

CHD1 Promotes Sensitivity to Aurora Kinase Inhibitors by Suppressing Interaction of AURKA with Its Coactivator TPX2

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Haoyan Li, Yin Wang, Kevin Lin, Varadha Balaji Venkadakrishnan, Martin Bakht, Wei Shi, Chenling Meng, Jie Zhang, Kaitlyn Tremble, Xin Liang, Jian H. Song, Xu Feng, Vivien Van, Pingna Deng, Jared K. Burks, Ana Aparicio, Khandan Keyomarsi, Junjie Chen, Yue Lu, Himisha Beltran, Di Zhao
Journal: Cancer Research
Cancer Res (2022) 82 (17): 3088–3101.
https://doi.org/10.1158/0008-5472.CAN-22-0631
Published: 02 September 2022
View articletitled, CHD1 Promotes Sensitivity to Aurora Kinase Inhibitors by Suppressing Interaction of AURKA with Its Coactivator TPX2
Open the PDF for CHD1 Promotes Sensitivity to Aurora Kinase Inhibitors by Suppressing Interaction of AURKA with Its Coactivator TPX2 in another window
Includes: Supplementary data
Journal Articles

Abstract P2-08-01: Validation of a 16-gene genomic signature to identify early-stage invasive breast cancer patients who may omit radiotherapy

Free
Anthony Fyles, S. Laura Chang, Katrina Rey-McIntyre, Wei Shi, Felix Feng, Corey Speers, Lori Pierce, David McCready, Fei-Fei Liu
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-08-01.
https://doi.org/10.1158/1538-7445.SABCS21-P2-08-01
Published: 15 February 2022
View articletitled, Abstract P2-08-01: Validation of a 16-gene genomic signature to identify early-stage invasive breast cancer patients who may omit radiotherapy
Journal Articles

Abstract 1644: Detection and quantification of lymphedema using optical coherence tomography lymphangiography

Free
Jennifer Y. Kwan, Valentin Demidov, Blake Jones, Wei Shi, Justin Williams, Costel Flueraru, Kenneth W. Yip, Fei-Fei Liu, Alex Vitkin
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1644.
https://doi.org/10.1158/1538-7445.AM2020-1644
Published: 15 August 2020
View articletitled, Abstract 1644: Detection and quantification of lymphedema using optical coherence tomography lymphangiography
Journal Articles

Arl13b Promotes Gastric Tumorigenesis by Regulating Smo Trafficking and Activation of the Hedgehog Signaling Pathway

Free
Jia Shao, Linlin Xu, Limin Chen, Quqin Lu, Xinsheng Xie, Wei Shi, Huanting Xiong, Chao Shi, Xuan Huang, Jinhong Mei, Hai Rao, Hua Lu, Nonghua Lu, Shiwen Luo
Journal: Cancer Research
Cancer Res (2017) 77 (15): 4000–4013.
https://doi.org/10.1158/0008-5472.CAN-16-2461
Published: 01 August 2017
View articletitled, Arl13b Promotes Gastric Tumorigenesis by Regulating Smo Trafficking and Activation of the Hedgehog Signaling Pathway
Open the PDF for Arl13b Promotes Gastric Tumorigenesis by Regulating Smo Trafficking and Activation of the Hedgehog Signaling Pathway in another window
Includes: Supplementary data
Journal Articles

Abstract 4752: Inflammatory cytokines and hematopoietic stem cells are associated with fatigue and insomnia in breast cancer patients undergoing adjuvant radiation therapy

Free
Wei Shi, Kathy Han, Madeline Li, Justin Williams, Megan McCusker, Jie Su, Wei Xu, Scott Bratman, Kenneth Yip, Fei-Fei Liu
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4752.
https://doi.org/10.1158/1538-7445.AM2017-4752
Published: 01 July 2017
View articletitled, Abstract 4752: Inflammatory cytokines and hematopoietic stem cells are associated with fatigue and insomnia in breast cancer patients undergoing adjuvant radiation therapy
Journal Articles

Abstract 3440: Time and regional incidence trends of human papillomavirus-associated oropharyngeal cancer in Ontario, Canada

Free
Wei Shi, Stephen F. Hall, Katrina Rey-McIntyre, Rebecca Griffiths, Wei Xu, Jie Su, Jeff Bruce, Shaohui Huang, Brian O’Sullivan, Kenneth W Yip, Fei-Fei Liu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3440.
https://doi.org/10.1158/1538-7445.AM2016-3440
Published: 15 July 2016
View articletitled, Abstract 3440: Time and regional incidence trends of human papillomavirus-associated oropharyngeal cancer in Ontario, Canada
Journal Articles

Abstract 1232: Regulation of ARHI and p53 gene on the programmed cell death of oral cancer cells

Free
Yi Li, Shan-Wei Shi, Chun-Jie Li, Bo Han, Long-Jiang Li
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1232.
https://doi.org/10.1158/1538-7445.AM2015-1232
Published: 01 August 2015
View articletitled, Abstract 1232: Regulation of ARHI and p53 gene on the programmed cell death of oral cancer cells
Journal Articles

Abstract P6-03-11: Erk5 as a therapeutic target in triple negative breast cancer (TNBC)

Free
Mariska Sauzine Miranda, Fares Al Ejeh, Wei Shi, Peter Simpson, Sunil Lakhani, Kum Kum Khanna
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P6-03-11.
https://doi.org/10.1158/1538-7445.SABCS14-P6-03-11
Published: 01 May 2015
View articletitled, Abstract P6-03-11: Erk5 as a therapeutic target in triple negative breast cancer (TNBC)
Journal Articles

Single-Strand DNA-Binding Protein SSB1 Facilitates TERT Recruitment to Telomeres and Maintains Telomere G-Overhangs

Free
Raj K. Pandita, Tracy T. Chow, Durga Udayakumar, Amanda L. Bain, Liza Cubeddu, Clayton R. Hunt, Wei Shi, Nobuo Horikoshi, Yong Zhao, Woodring E. Wright, Kum Kum Khanna, Jerry W. Shay, Tej K. Pandita
Journal: Cancer Research
Cancer Res (2015) 75 (5): 858–869.
https://doi.org/10.1158/0008-5472.CAN-14-2289
Published: 01 March 2015
View articletitled, Single-Strand DNA-Binding Protein SSB1 Facilitates TERT Recruitment to Telomeres and Maintains Telomere G-Overhangs
Open the PDF for Single-Strand DNA-Binding Protein SSB1 Facilitates TERT Recruitment to Telomeres and Maintains Telomere G-Overhangs in another window
Includes: Supplementary data
Journal Articles

Abstract 4372: MiR-449a promotes breast cancer progression by activating the NF-κB pathway

Free
Wei Shi, Matthew Lee, Ryunosuke Kogo, Jeff Bruce, Christine How, Kenneth W. Yip, Fei-Fei Liu
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4372.
https://doi.org/10.1158/1538-7445.AM2014-4372
Published: 01 October 2014
View articletitled, Abstract 4372: MiR-449a promotes breast cancer progression by activating the NF-κB pathway
Journal Articles

Abstract 2490: Integrative systems analysis of HPV+ and HPV- oropharyngeal carcinomas

Free
Lusia Sepiashvili, Angela Hui, Wei Shi, Wei Xu, Daryl Waggot, Paul Boutros, Alex Ignatchenko, Vladimir Ignatchenko, Shao Hui (Sophie) Huang, John Waldron, Brian O'Sullivan, Jonathan C. Irish, Fei-Fei Liu, Thomas Kislinger
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2490.
https://doi.org/10.1158/1538-7445.AM2014-2490
Published: 01 October 2014
View articletitled, Abstract 2490: Integrative systems analysis of HPV+ and HPV- oropharyngeal carcinomas