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Journal Articles

Ephrin A1 Stimulates CCL2 Secretion to Facilitate Premetastatic Niche Formation and Promote Gastric Cancer Liver Metastasis

Yun Cui, Yongxia Chang, Xixi Ma, Meng Sun, Yuliang Huang, Feng Yang, Shuang Li, Wei Zhuo, Wei Liu, Bo Yang, Aifu Lin, Guangshuo Ou, Yuehong Yang, Shanshan Xie, Tianhua Zhou
Journal: Cancer Research
Cancer Res (2025) 85 (2): 263–276.
https://doi.org/10.1158/0008-5472.CAN-24-1254
Published: 15 January 2025
View article titled, Ephrin A1 Stimulates CCL2 Secretion to Facilitate Premetastatic Niche Formation and Promote Gastric Cancer Liver Metastasis
Open the PDF for Ephrin A1 Stimulates CCL2 Secretion to Facilitate Premetastatic Niche Formation and Promote Gastric Cancer Liver Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract PO1-29-03: Efficacy, Safety, and Immunogenicity of TQ-B211 (a Trastuzumab Biosimilar) Plus Docetaxel versus Herceptin® Plus Docetaxel for HER2-positive Metastatic Breast Cancer: a Double-blind, Randomised, Multicenter, Phase 3 Trial

Xichun Hu, Qingyuan Zhang, Shusen Wang, Tao Sun, Xiaohua Zeng, Weimin Xie, Zhongsheng Tong, Hui Cao, Huihua Xiong, Xiuwen Wang, Jin Yang, Shuqun Zhang, Ying Wang, Chunhong Hu, Kaijian Lei, Binlin Ma, Wei Liu, Zhiyong Yu, PeiJian Peng, Hongwei Yang, Zhijun Yuan, Xiaojia Wang, Xujuan Wang, Hong Wang, Yongqian Shu, Nanlin Li, Wenbin Yue, Jingfen Wang, Daqing Wang, Zhiguo Luo, Junyang Mo, Yarong Li, Lili Sheng
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-29-03.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-29-03
Published: 02 May 2024
View article titled, Abstract PO1-29-03: Efficacy, Safety, and Immunogenicity of TQ-B211 (a Trastuzumab Biosimilar) Plus Docetaxel versus Herceptin® Plus Docetaxel for HER2-positive Metastatic Breast Cancer: a Double-blind, Randomised, Multicenter, Phase 3 Trial
Journal Articles

Abstract LT09: Integrative Multi-Omics Enhancer Activity Profiling Identifies Therapeutic Vulnerabilities in Cholangiocarcinoma of Different Etiologies

Jing Han Hong, Chern Han Yong, Hong Lee Heng, Jason Yongsheng Chan, Mai Chan Lau, Jianfeng Chen, Jing Yi Lee, Abner Herbert Lim, Zhimei Li, Peiyong Guan, Pek Lim Chu, Sheng Rong Ng, Xiaosai Yao, Peili Wang, Rong Xiao, Xian Zeng, Yichen Sun, Wei Liu, Joanna Koh, Felicia Yu Ting Wee, Jeffrey Chun Tatt Lim, Cedric Chuan Young Ng, Xiu Yi Kwek, Poramate Klanrit, Yaojun Zhang, Jiaming Lai, David Wai Meng Tai, Chawalit Pairojkul, Simona Dima, Irinel Popescu, Sen-Yung Hsieh, Ming-Chin Yu, Joe Yeong, Sarinya Kongpetch, Apinya Jusakul, Watcharin Loilome, Patrick Tan, Jing Tan, Bin Tean Teh
Journal: Cancer Research
Cancer Res (2024) 84 (8_Supplement): LT09.
https://doi.org/10.1158/1538-7445.FCS2023-LT09
Published: 15 April 2024
View article titled, Abstract LT09: Integrative Multi-Omics Enhancer Activity Profiling Identifies Therapeutic Vulnerabilities in Cholangiocarcinoma of Different Etiologies
Journal Articles

Abstract LB247: TCPAplus: An LLM-empowered chatbot for analyzing a large protein expression atlas of human cancers

Wei Liu, Jun Liu, Yitao Tang, Chaozhong Liu, Meiyi Song, Zhenlin Ju, Shweth V. Kumar, Yiling Lu, Rehan Akbani, Gordon Mills, Han Liang
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB247.
https://doi.org/10.1158/1538-7445.AM2024-LB247
Published: 05 April 2024
View article titled, Abstract LB247: TCPAplus: An LLM-empowered chatbot for analyzing a large protein expression atlas of human cancers
Journal Articles

Abstract CT093: Vaccine immunotherapy by homologous antigenic loading as adjuvant therapy for glioblastoma: Ongoing phase I analysis

Joseph F. Georges, Mazen Zaher, Corey M. Mossop, Christopher J. Bilbao, Christina M. Clay, Sabina Amin, Hamza A. Shaikh, Akshar Trivedi, Wei Liu, Madhuri Namekar, Colby J. Hofferek, Keenan Ernste, Eva H. Schumann, Mia Vu, Damilola Oyewole-Said, Nalini Bisht, Jonathan Vazquez-Perez, Ashley M. Goralczyk, Lindsey Colman, Lynne S. Kohler, Thuy V. Cao, Ngozi Okereke, Benjamin L. Musher, Vinod Ravi, Jan O. Kemnade, Rodrick C. Zvavanjanja, Jay-Jiguang Zhu, Sigmund H. Hsu, Yoshua Esquenazi-Levy, Nitin Tandon, Alan Turtz, Vanaja Konduri, William Karl Decker
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT093.
https://doi.org/10.1158/1538-7445.AM2024-CT093
Published: 05 April 2024
View article titled, Abstract CT093: Vaccine immunotherapy by homologous antigenic loading as adjuvant therapy for glioblastoma: Ongoing phase I analysis
Journal Articles

Abstract 3124: MRG006A, a novel glypican-3-targeting antibody-drug conjugate, demonstrated potent anti-tumor activity and good safety profile in preclinical studies

Yanchun Wang, Hongfeng Li, Hao Shen, Wenchao Liu, Shoujia Liu, Kequan Yin, Haili Xu, Xueyuan Cui, Wei Li, Wei Liu, Xiangyu Wu, Liu Yang, Tian Ma, Zhongrun Zhao, Jun Wang, Feifei Cui, Lei Fang, Minmin Qin, Chaohong Hu
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3124.
https://doi.org/10.1158/1538-7445.AM2024-3124
Published: 22 March 2024
View article titled, Abstract 3124: MRG006A, a novel glypican-3-targeting antibody-drug conjugate, demonstrated potent anti-tumor activity and good safety profile in preclinical studies
Journal Articles

Abstract 1531: TIL analysis demonstrates different mechanisms underlying PD-1 resistance in animal models

Sha Qiao, Yujia Liu, Wei Liu, Wenqian Pan, Xiaofei Zhou, Linlin Wang, Mengya Chai, Yujie Liu, Hao Yang, Zhaoxue Yu
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1531.
https://doi.org/10.1158/1538-7445.AM2024-1531
Published: 22 March 2024
View article titled, Abstract 1531: TIL analysis demonstrates different mechanisms underlying PD-1 resistance in animal models
Journal Articles

Abstract 4931: The Cancer Proteome Atlas: Expanded datasets and empowered with an AI-driven chatbot

Han Liang, Wei Liu, Jun Li, Yitao Tang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4931.
https://doi.org/10.1158/1538-7445.AM2024-4931
Published: 22 March 2024
View article titled, Abstract 4931: The Cancer Proteome Atlas: Expanded datasets and empowered with an AI-driven chatbot
Journal Articles

Abstract 7295: A novel XNA technology-based assay to detect JAK2 V617F mutation by real-time PCR

Shuo Shen, Robert Brown, Daniel Kim, Larry Pastor, Andrew Y. Fu, Pushpinder Kaur, Alisha Babu, Wei Liu, Aiguo Zhang, Hiromi Tanaka, Michael Y. Sha
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7295.
https://doi.org/10.1158/1538-7445.AM2024-7295
Published: 22 March 2024
View article titled, Abstract 7295: A novel XNA technology-based assay to detect JAK2 V617F mutation by real-time PCR
Journal Articles

Abstract 1179: A single-cell atlas of human gastric malignancy reveals CD8+ T cell rejuvenation as a mediator of immunotherapeutic response

Han Liang, Jian Chen, Yikai Luo, Muxing Kang, Wei Liu, Lie Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1179.
https://doi.org/10.1158/1538-7445.AM2024-1179
Published: 22 March 2024
View article titled, Abstract 1179: A single-cell atlas of human gastric malignancy reveals CD8+ T cell rejuvenation as a mediator of immunotherapeutic response
Journal Articles

Abstract 3904: Multiplexed flow cytometry based immunophenotyping paired with functional ex vivo (MFLEX) drug profiling informs potential efficacy of therapeutic agents in acute myeloid leukemia

Reecha Shah, Heba Wander, Michelle Hsueh, Muskan Floren, Wei Liu, Patricia Cheung, Courtney Andersen, Michael White, Nathan Kingston, Pablo Morentin Gutierrez, Lisa Drew, Giulia Fabbri, Elena Bibikova, Daniel Auclair
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3904.
https://doi.org/10.1158/1538-7445.AM2024-3904
Published: 22 March 2024
View article titled, Abstract 3904: Multiplexed flow cytometry based immunophenotyping paired with functional <em>ex vivo</em> (MFLEX) drug profiling informs potential efficacy of therapeutic agents in acute myeloid leukemia
Journal Articles

Genome-Wide Splicing Quantitative Expression Locus Analysis Identifies Causal Risk Variants for Non–Small Cell Lung Cancer

Meng Jin, Bo Liu, Can Chen, Yongbiao Huang, Huixian Zhang, Bingliang Chen, Guoda Song, Dong Zhao, Limin Duan, Wei Liu, Haizhen Yang, Fang Yue, Peijun Liu, Xianglin Yuan, Qian Chu, Jianbo Tian, Ke Hu
Journal: Cancer Research
Cancer Res (2023) 83 (10): 1742–1756.
https://doi.org/10.1158/0008-5472.CAN-22-3184
Published: 15 May 2023
View article titled, Genome-Wide Splicing Quantitative Expression Locus Analysis Identifies Causal Risk Variants for Non–Small Cell Lung Cancer
Open the PDF for Genome-Wide Splicing Quantitative Expression Locus Analysis Identifies Causal Risk Variants for Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 5738: A pan-ras mRNA vaccine elicits specific immune responses and inhibits tumor growth in the mouse model of colon cancer

Renxiang Chen, Wei Liu, David M. Brown, Yong-Sik Bong, Jiaxi He, Dong Shen, Cun Yu Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5738.
https://doi.org/10.1158/1538-7445.AM2023-5738
Published: 04 April 2023
View article titled, Abstract 5738: A pan-ras mRNA vaccine elicits specific immune responses and inhibits tumor growth in the mouse model of colon cancer
Journal Articles

Abstract 2530: DELE1 loss and dysfunctional integrated stress signaling in TP53 mutated AML is a novel pathway for venetoclax resistance

David Sharon, Paul Jung, Yan Sun, Weiguo Feng, Ziping Yang, Valerie Robinson, Diya Mitra, Wei Liu, Pingping Zheng, Tamar Uziel, Lloyd Lam, Mark D. Minden, Jeremy Ross, Wellington Mendes, Jalaja Potluri, Andrew H. Wei, Marina Konopleva, Monique Dail, Brenda Chyla, PK Epling-Burnette
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2530.
https://doi.org/10.1158/1538-7445.AM2023-2530
Published: 04 April 2023
View article titled, Abstract 2530: DELE1 loss and dysfunctional integrated stress signaling in <em>TP53</em> mutated AML is a novel pathway for venetoclax resistance
Journal Articles

Abstract 2878: Identification of immunosuppressive and tumor-promoting neutrophils in human bone marrow and a novel mouse model that supports human neutrophil engraftment

Wei Liu, Keying Che, Chun Lu, Jia Wei, Yan Li
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2878.
https://doi.org/10.1158/1538-7445.AM2023-2878
Published: 04 April 2023
View article titled, Abstract 2878: Identification of immunosuppressive and tumor-promoting neutrophils in human bone marrow and a novel mouse model that supports human neutrophil engraftment
Journal Articles

Abstract 4965: Targeting the mitotic kinesin, KIF18A, in chromosomally unstable cancers

James D. Joseph, Katherine Schutt, Kira Fisher, Katelyn Queen, Olivia Budington, Weifeng Mao, Wei Liu, Zhengqing Zhu, Xiangping Zhang, Yisong Xiao, Kunmin Lai, Xiaohui Gu, Jason Stumpff, Fred Aswad
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4965.
https://doi.org/10.1158/1538-7445.AM2023-4965
Published: 04 April 2023
View article titled, Abstract 4965: Targeting the mitotic kinesin, KIF18A, in chromosomally unstable cancers
Journal Articles

Abstract 6234: Targeting integrin alpha V beta 5 heterodimer stability using a novel small molecular inhibitor for tumor suppression

Nicole Mattson, Kazuya Miyashita, Anthony Chan, Lu Yang, Sheela Pangeni Pokharel, Wei Liu, Ming li, Qiao Liu, Xiaobao Xu, Priyanka Singh, Leisi Zhang, Mingye Feng, Chun-Wei Chen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6234.
https://doi.org/10.1158/1538-7445.AM2023-6234
Published: 04 April 2023
View article titled, Abstract 6234: Targeting integrin alpha V beta 5 heterodimer stability using a novel small molecular inhibitor for tumor suppression
Journal Articles

Abstract 6308: Preclinical development of ABBV-319: a CD19-targeting glucocorticoid receptor modulator (GRM) agonist antibody-drug conjugate (ADC) for the treatment of B-cell malignancies

Chewei Anderson Chang, Ethan Emberley, Aloma L. D'Souza, Weilong Zhao, Cormac Cosgrove, Axel Hernandez Jr, Anatol Oleksijew, Paul Ellis, Luis Rodriguez, Gail Bukofzer, David Peetz, Wissam Assaily, Raghuveer Singh Mali, Wei Liu, Danqing Xu, Gregory K. Potts, Shaun McLoughlin, Kimberley McCarthy, Zhaomei Zhang, Jos Campbell, Isabella Sturdevant, Gloria Zhang, Tyler Curran, Jon D. Williams, Erwin Boghaert, Milan Bruncko, Christopher C. Marvin, Adrian Hobson, Michael Mcpherson, Tamar Uziel, Marybeth Pysz, Xi Zhao, Alex Bankovich, Kevin J. Freise, Susan Morgan-Lappe, James W. Purcell
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6308.
https://doi.org/10.1158/1538-7445.AM2023-6308
Published: 04 April 2023
View article titled, Abstract 6308: Preclinical development of ABBV-319: a CD19-targeting glucocorticoid receptor modulator (GRM) agonist antibody-drug conjugate (ADC) for the treatment of B-cell malignancies
Journal Articles

Abstract 3298: Two detection methods of clinical KRAS G12C mutation detection for companion diagnostics

Robert William Brown, Wei Liu, Qing Sun, Hui Ren, Jonathan Li, Larry Pastor, Daniel Kim, Michael Sha, Aiguo Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3298.
https://doi.org/10.1158/1538-7445.AM2023-3298
Published: 04 April 2023
View article titled, Abstract 3298: Two detection methods of clinical KRAS G12C mutation detection for companion diagnostics
Journal Articles

Abstract 6681: XNA increases assay sensitivity in sanger sequencing, qPCR, NGS and CRISPR mutant screening

Wei Liu, Robert Brown, Andrew Fu, Shuo Shen, Michael Sha, Aiguo Zhang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6681.
https://doi.org/10.1158/1538-7445.AM2023-6681
Published: 04 April 2023
View article titled, Abstract 6681: XNA increases assay sensitivity in sanger sequencing, qPCR, NGS and CRISPR mutant screening