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Journal Articles

RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis

Danyu Chen, Fenfen Ji, Qiming Zhou, Henley Cheung, Yasi Pan, Harry C.-H. Lau, Cong Liang, Zhenjie Yang, Pingmei Huang, Qinyao Wei, Alvin H.-K. Cheung, Wei Kang, Huarong Chen, Jun Yu, Chi Chun Wong
Journal: Cancer Research
Cancer Res (2024) 84 (17): 2856–2872.
https://doi.org/10.1158/0008-5472.CAN-23-2081
Published: 04 September 2024
View article titled, RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m<sup>6</sup>A-Dependent Oncogenic Translation and Colorectal Tumorigenesis
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Includes: Supplementary data
Journal Articles

FOXP4 is a Direct YAP1 Target that Promotes Gastric Cancer Stemness and Drives Metastasis

Xiaoli Liu, Bonan Chen, Fuda Xie, Kit Yee. Wong, Alvin Ho-Kwan. Cheung, Jinglin Zhang, Qian Wu, Canbin Fang, Jintao Hu, Shouyu Wang, Dazhi Xu, Jianwu Chen, Yuzhi Wang, Chi Chun. Wong, Huarong Chen, William Ka Kei. Wu, Jun Yu, Michael W.Y. Chan, Chi Man. Tsang, Kwok Wai. Lo, Gary M.K. Tse, Ka-Fai To, Wei Kang
Journal: Cancer Research
Cancer Res (2024)
https://doi.org/10.1158/0008-5472.CAN-23-3074
Published: 24 July 2024
View article titled, FOXP4 is a Direct YAP1 Target that Promotes Gastric Cancer Stemness and Drives Metastasis
Open the PDF for FOXP4 is a Direct YAP1 Target that Promotes Gastric Cancer Stemness and Drives Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 6524: Single-cell landscape of cancer-associated fibroblasts in immunotherapy resistance of hepatocellular carcinoma

Patrick Pak-Chun Wong, Jianquan Cao, Zhewen Xiong, Haoran Wu, Qin Cao, Bonan Chen, Ka-Fai To, Stephen Lam Chan, Wei Kang, Alfred Sze-Lok Cheng
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6524.
https://doi.org/10.1158/1538-7445.AM2024-6524
Published: 22 March 2024
View article titled, Abstract 6524: Single-cell landscape of cancer-associated fibroblasts in immunotherapy resistance of hepatocellular carcinoma
Journal Articles

Single-Hit Inactivation Drove Tumor Suppressor Genes Out of the X Chromosome during Evolution

Xiansong Wang, Wei Hu, Xiangchun Li, Dan Huang, Qing Li, Hung Chan, Judeng Zeng, Chuan Xie, Huarong Chen, Xiaodong Liu, Tony Gin, Maggie Haitian Wang, Alfred Sze Lok Cheng, Wei Kang, Ka-Fai To, Dariusz Plewczynski, Qingpeng Zhang, Xiaoting Chen, Danny Cheuk Wing Chan, Ho Ko, Sunny Hei Wong, Jun Yu, Matthew Tak Vai Chan, Lin Zhang, William Ka Kei Wu
Journal: Cancer Research
Cancer Res (2022) 82 (8): 1482–1491.
https://doi.org/10.1158/0008-5472.CAN-21-3458
Published: 15 April 2022
View article titled, Single-Hit Inactivation Drove Tumor Suppressor Genes Out of the X Chromosome during Evolution
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Includes: Supplementary data
Journal Articles

RNF6 Promotes Colorectal Cancer by Activating the Wnt/β-Catenin Pathway via Ubiquitination of TLE3

Lei Liu, Yanquan Zhang, Chi Chun Wong, Jingwan Zhang, Yujuan Dong, Xiangchun Li, Wei Kang, Francis K.L. Chan, Joseph J.Y. Sung, Jun Yu
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (8): 1958–1971.
https://doi.org/10.1158/0008-5472.CAN-17-2683
Published: 12 April 2018
View article titled, RNF6 Promotes Colorectal Cancer by Activating the Wnt/β-Catenin Pathway via Ubiquitination of TLE3
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Includes: Supplementary data
Journal Articles

Forkhead Box F2 Suppresses Gastric Cancer through a Novel FOXF2–IRF2BPL–β-Catenin Signaling Axis

Akira Higashimori, Yujuan Dong, Yanquan Zhang, Wei Kang, Geicho Nakatsu, Simon S.M. Ng, Tetsuo Arakawa, Joseph J.Y. Sung, Francis K.L. Chan, Jun Yu
Journal: Cancer Research
Cancer Res (2018) 78 (7): 1643–1656.
https://doi.org/10.1158/0008-5472.CAN-17-2403
Published: 01 April 2018
View article titled, Forkhead Box F2 Suppresses Gastric Cancer through a Novel FOXF2–IRF2BPL–β-Catenin Signaling Axis
Open the PDF for Forkhead Box F2 Suppresses Gastric Cancer through a Novel FOXF2–IRF2BPL–β-Catenin Signaling Axis in another window
Includes: Supplementary data
Journal Articles

Sodium Channel Subunit SCNN1B Suppresses Gastric Cancer Growth and Metastasis via GRP78 Degradation

Yun Qian, Chi Chun Wong, Jiaying Xu, Huarong Chen, Yanquan Zhang, Wei Kang, Hua Wang, Li Zhang, Weilin Li, Eagle S.H. Chu, Minnie Y.Y. Go, Philip W.Y. Chiu, Enders K.W. Ng, Francis K.L. Chan, Joseph J.Y. Sung, Jianmin Si, Jun Yu
Journal: Cancer Research
Cancer Res (2017) 77 (8): 1968–1982.
https://doi.org/10.1158/0008-5472.CAN-16-1595
Published: 13 April 2017
View article titled, Sodium Channel Subunit SCNN1B Suppresses Gastric Cancer Growth and Metastasis via GRP78 Degradation
Open the PDF for Sodium Channel Subunit SCNN1B Suppresses Gastric Cancer Growth and Metastasis via GRP78 Degradation in another window
Includes: Supplementary data
Journal Articles

Epigenetic Silencing of miR-490-3p Reactivates the Chromatin Remodeler SMARCD1 to Promote Helicobacter pylori–Induced Gastric Carcinogenesis

Jing Shen, Zhangang Xiao, William K.K. Wu, Maggie H. Wang, Ka F. To, Yangchao Chen, Weiqin Yang, May S.M. Li, Vivian Y. Shin, Joanna H. Tong, Wei Kang, Lin Zhang, Minxing Li, Lin Wang, Lan Lu, Ruby L.Y. Chan, Sunny H. Wong, Jun Yu, Matthew T.V. Chan, Francis K.L. Chan, Joseph J.Y. Sung, Alfred S.L. Cheng, Chi H. Cho
Journal: Cancer Research
Cancer Res (2015) 75 (4): 754–765.
https://doi.org/10.1158/0008-5472.CAN-14-1301
Published: 15 February 2015
View article titled, Epigenetic Silencing of miR-490-3p Reactivates the Chromatin Remodeler SMARCD1 to Promote <em>Helicobacter pylori</em>–Induced Gastric Carcinogenesis
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Includes: Supplementary data
Journal Articles

Abstract 1245: Reactivation of growth/differentiation factor 1 contributes to the chemopreventive effect of 5-aza-2′deoxycytidine in gastric cancer

Wei Qin Yang, May S. M. Li, Wei Kang, Li Han Zeng, Tian Hai Wang, Anthony W. Chan, Enders K. W. Ng, Ka F. To, Francis K. L. Chan, Jun Yu, Michael W.Y. Chan, Joseph J. Y. Sung, Alfred S. L. Cheng
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1245.
https://doi.org/10.1158/1538-7445.AM2014-1245
Published: 01 October 2014
View article titled, Abstract 1245: Reactivation of growth/differentiation factor 1 contributes to the chemopreventive effect of 5-aza-2′deoxycytidine in gastric cancer