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Wei Huang
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Journal Articles

Abstract LB338: A novel class of T cell-activators targeting germline encoded TCRβ chains promotes antitumor activity in PD1-refractory models through expansion of a clonally enriched effector memory T cell subset

Jacques Moisan, Madan Katraggada, Jonathan Hsu, Jessica Lowry, Wei Huang, Jian Tang, Roya Servattalab, Gurkan Guntas, Raj Chopra, Zhen Su, Andrew Bayliffe
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB338.
https://doi.org/10.1158/1538-7445.AM2023-LB338
Published: 14 April 2023
View article titled, Abstract LB338: A novel class of T cell-activators targeting germline encoded TCRβ chains promotes antitumor activity in PD1-refractory models through expansion of a clonally enriched effector memory T cell subset
Journal Articles

Abstract 5408: AI powered-platform to predict gene modifications from prostate and breast cancer whole slide images

Wei Huang, Parag Jain, Chensu Xie, Hassan Muhammad, Hirak Basu, George Wilding, Rajat Roy
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5408.
https://doi.org/10.1158/1538-7445.AM2023-5408
Published: 04 April 2023
View article titled, Abstract 5408: AI powered-platform to predict gene modifications from prostate and breast cancer whole slide images
Journal Articles

Abstract 3636: Liver endothelium secreted LRG1 promotes metastatic colorectal cancer growth through the HER3/RSK/EIF4B AXIS

Moeez Ghani Rathore, Michelle Wright, Wei Huang, Derek Taylor, Yamu Li, Jordan Winter, Zhenghe Wang, John Greenwood, Stephen Moss, Rui Wang
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3636.
https://doi.org/10.1158/1538-7445.AM2023-3636
Published: 04 April 2023
View article titled, Abstract 3636: Liver endothelium secreted LRG1 promotes metastatic colorectal cancer growth through the HER3/RSK/EIF4B AXIS
Journal Articles

Abstract 4491: TY-0584: A potent, orally available small molecule YAP/TEAD inhibitor, exhibits anti-tumor effects in vitro and in vivo

Apeng Liang, Shengli Dong, Guangbin Liu, Zhengfei Guo, Meihua Li, Shuaibo Han, Yundi Cao, Yian Tu, Chao Zhou, Yu Yu, Linglin Xiao, Wei Huang, Xinlong Yang, Lian Fang, Haoyun Li, Chengshan Niu, Mingyu Jiang, Feng Xing, Shaoqing Chen, Jun Li, Yusheng Wu
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4491.
https://doi.org/10.1158/1538-7445.AM2023-4491
Published: 04 April 2023
View article titled, Abstract 4491: TY-0584: A potent, orally available small molecule YAP/TEAD inhibitor, exhibits anti-tumor effects <em>in vitro</em> and <em>in vivo</em>
Journal Articles

Abstract 477: Discovery of RGT-018: A potent, selective and orally bioavailable SOS1 inhibitor for mutant KRAS-driven cancers

Fei Xiao, Kailiang Wang, Xinjuan Wang, Huijuan Li, Zhilong Hu, Wei Huang, Xiaoming Ren, Teng Feng, Lili Yao, Jing Lin, Chunlai Li, Liufeng Mei, Zhuanzhuan Zhang, Yangyang Liu, Xi Chen, Xiaotian Zhu, Wenge Zhong, Zhi Xie
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 477.
https://doi.org/10.1158/1538-7445.AM2023-477
Published: 04 April 2023
View article titled, Abstract 477: Discovery of RGT-018: A potent, selective and orally bioavailable SOS1 inhibitor for mutant KRAS-driven cancers
Journal Articles

Abstract P6-01-18: Predicting response of triple negative breast cancer to neoadjuvant chemotherapy using a deep convolutional neural network-based artificial intelligence tool

Savitri Krishnamurthy, Parag Jain, Debu Tripathy, Hassan Muhammad, Wei huang, Hua Yang, Shivaani Kummar, George Wilding, Rajat Roy, Ramandeep Randhawa
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P6-01-18.
https://doi.org/10.1158/1538-7445.SABCS22-P6-01-18
Published: 01 March 2023
View article titled, Abstract P6-01-18: Predicting response of triple negative breast cancer to neoadjuvant chemotherapy using a deep convolutional neural network-based artificial intelligence tool
Journal Articles

Abstract 5461: H002: A wide spectrum, highly selective fourth-generation EGFR inhibitor overcoming resistance harboring C797S mutation in NSCLC

Wei Huang, Lin Zhu, Xiaoe Yan, Xin Huang, Jia Hao, Shan Li, Xiangyu Li, Zhiming Chen, Yunchuan Jia, Haibo Li, Jianming Zhang, Xianming Deng, Caihong Yun
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5461.
https://doi.org/10.1158/1538-7445.AM2022-5461
Published: 15 June 2022
View article titled, Abstract 5461: H002: A wide spectrum, highly selective fourth-generation EGFR inhibitor overcoming resistance harboring C797S mutation in NSCLC
Journal Articles

Chromatin Remodeling Induced by ARID1A Loss in Lung Cancer Promotes Glycolysis and Confers JQ1 Vulnerability

Xiaoyu Liu, Zhi Li, Zhongmin Wang, Fei Liu, Linling Zhang, Jingjing Ke, Xu Xu, Yuefang Zhang, Yiting Yuan, Tao Wei, Qungang Shan, Yingjie Chen, Wei Huang, Jie Gao, Nan Wu, Fuliang Chen, Lunquan Sun, Zilong Qiu, Yuezhen Deng, Xiaojing Wang
Journal: Cancer Research
Cancer Res (2022) 82 (5): 791–804.
https://doi.org/10.1158/0008-5472.CAN-21-0763
Published: 03 March 2022
View article titled, Chromatin Remodeling Induced by ARID1A Loss in Lung Cancer Promotes Glycolysis and Confers JQ1 Vulnerability
Open the PDF for Chromatin Remodeling Induced by ARID1A Loss in Lung Cancer Promotes Glycolysis and Confers JQ1 Vulnerability in another window
Includes: Supplementary data
Journal Articles

Abstract P4-06-02: Clinically feasible pharmacokinetic model of dynamic contrast-enhanced MRI is prognostic of recurrence free survival in breast cancer patients treated with neoadjuvant therapy

Joseph R Peterson, Tyler M. Earnest, Wei Huang, Hiroyuki Abe, John A Cole, Jr.
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P4-06-02.
https://doi.org/10.1158/1538-7445.SABCS21-P4-06-02
Published: 15 February 2022
View article titled, Abstract P4-06-02: Clinically feasible pharmacokinetic model of dynamic contrast-enhanced MRI is prognostic of recurrence free survival in breast cancer patients treated with neoadjuvant therapy
Journal Articles

Abstract 2788: Deep characterization of tumor infiltrating leukocytes using a combination of flow cytometry and single-cell multiomics

Xiaoshan Shi, Margaret Nakamoto, Aaron Middlebrook, Wei Huang, Evelyn Lo, Patrick T. Neuhoefer, Scott Bornheimer, Smita Ghanekar
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2788.
https://doi.org/10.1158/1538-7445.AM2021-2788
Published: 01 July 2021
View article titled, Abstract 2788: Deep characterization of tumor infiltrating leukocytes using a combination of flow cytometry and single-cell multiomics
Journal Articles

ANXA1 Binds and Stabilizes EphA2 to Promote Nasopharyngeal Carcinoma Growth and Metastasis

Juan Feng, Shan-Shan Lu, Ta Xiao, Wei Huang, Hong Yi, Wei Zhu, Songqing Fan, Xue-Ping Feng, Jiao-Yang Li, Zheng-Zheng Yu, Song Gao, Guo-Hui Nie, Yao-Yun Tang, Zhi-Qiang Xiao
Journal: Cancer Research
Cancer Res (2020) 80 (20): 4386–4398.
https://doi.org/10.1158/0008-5472.CAN-20-0560
Published: 15 October 2020
View article titled, ANXA1 Binds and Stabilizes EphA2 to Promote Nasopharyngeal Carcinoma Growth and Metastasis
Open the PDF for ANXA1 Binds and Stabilizes EphA2 to Promote Nasopharyngeal Carcinoma Growth and Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 2981: Biased activation of PP2A through selective heterotrimer binding and stabilization

Daniel Leonard, Wei Huang, Sudeh Izadmehr, Caitlin M. O'Connor, Danica D. Wiredja, Zhizhi Wang, Nilesh Zaware, Daniela M. Schlatzer, Stefan Schuchner, Janna Kiselar, Yinghua Chen, Nikhil Vasireddi, Abbey L. Perl, Matthew D. Glasky, Wenqing Xu, David L. Brautigan, Egon Ogris, Derek J. Taylor, Goutham Narla
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2981.
https://doi.org/10.1158/1538-7445.AM2020-2981
Published: 15 August 2020
View article titled, Abstract 2981: Biased activation of PP2A through selective heterotrimer binding and stabilization
Journal Articles

Abstract 4474: A quantitative flow cytometry method for the measurement of HLA-DR expression level on monocyte subsets

Wei Huang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4474.
https://doi.org/10.1158/1538-7445.AM2020-4474
Published: 15 August 2020
View article titled, Abstract 4474: A quantitative flow cytometry method for the measurement of HLA-DR expression level on monocyte subsets
Journal Articles

Abstract 6197: Improving sample preparation workflows for single cell multiomic analysis of infiltrating leukocytes from solid tumors

Aaron J. Middlebrook, Wei Huang, Margaret Nakamoto, Xiaoshan Shi, Evelyn Lo, Patrick Neuhoefer, Scott Bornheimer, Smita Ghanekar
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6197.
https://doi.org/10.1158/1538-7445.AM2020-6197
Published: 15 August 2020
View article titled, Abstract 6197: Improving sample preparation workflows for single cell multiomic analysis of infiltrating leukocytes from solid tumors
Journal Articles

Abstract 2097: AI powered platform to identify primary prostate cancer patients with high risk of recurrence

Wei Huang, Parag Jain, Raman Randhawa, Bijay Jaiswal, Samuel Hubbard, Hirak Basu, Rajat Roy
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2097.
https://doi.org/10.1158/1538-7445.AM2020-2097
Published: 15 August 2020
View article titled, Abstract 2097: AI powered platform to identify primary prostate cancer patients with high risk of recurrence
Journal Articles

Abstract P4-09-01: Clinical sequencing characterizes the genomic landscape and actionable mutations of Chinese breast cancer

Guan-Tian Lang, Jin-Xiu Shi, Yi-Zhou Jiang, Xiao-Guang Li, Yu-Chen Pei, Fang-Lin Zhang, Chen-Hui Zhang, Ding Ma, Yi Xiao, Ke-Da Yu, Peng-Chen Hu, Ming-Liang Jin, Hai Wang, Yun-Song Yang, Xuan Luo, Qi Hong, Feng Qiao, Wei-Li Sun, Meng-Zhu Xue, Shi-Ping Li, A-Yong Cao, Zhong-Hua Wang, Jia-Xin Zhang, Gen-Hong Di, Peng Wang, Da-Qiang Li, Xin Hu, Wei Huang, Zhi-Ming Shao
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P4-09-01.
https://doi.org/10.1158/1538-7445.SABCS19-P4-09-01
Published: 15 February 2020
View article titled, Abstract P4-09-01: Clinical sequencing characterizes the genomic landscape and actionable mutations of Chinese breast cancer
Journal Articles

Abstract P4-05-02: Machine learning predicts rapid relapse in triple negative breast cancer

Yiqing Zhang, William Nock, Meghan Wyse, Zachary Weber, Elizabeth J Adams, Asad Sarah, Sinclair Stockard, David Tallman, Jasneet Singh, Junu Bae, Eric P Winer, Nancy U Lin, Yi-Zhou Jiang, Ding Ma, Peng Wang, Leming Shi, Wei Huang, Zhi-Ming Shao, Claire Verschraegen, Mathew Cherian, Maryam B Lustberg, Bhuvana Ramaswamy, Sagar Sardesai, Jeffrey VanDeusen, Nicole Williams, Wesolowski Robert, Daniel G Stover
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P4-05-02.
https://doi.org/10.1158/1538-7445.SABCS19-P4-05-02
Published: 15 February 2020
View article titled, Abstract P4-05-02: Machine learning predicts rapid relapse in triple negative breast cancer
Journal Articles

Abstract P5-12-14: The impact of pre-existed and SERM-induced non-alcoholic fatty liver disease on breast cancer survival: A meta-analysis

Yu Song, Changjun Wang, Wei Huang, Yidong Zhou, Ziyuan Chen, Hanjiang Zhu, Feng Mao, Yan Lin, Xiaohui Zhang, Songjie Shen, Ying Zhong, Xin Huang, Chang Chen, Qiang Sun
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-12-14.
https://doi.org/10.1158/1538-7445.SABCS19-P5-12-14
Published: 15 February 2020
View article titled, Abstract P5-12-14: The impact of pre-existed and SERM-induced non-alcoholic fatty liver disease on breast cancer survival: A meta-analysis
Journal Articles

Abstract 1251: Potential tumor suppressor function of polo-like kinase 5 in ovarian cancers

Mary A. Ndiaye, Shengqin Su, Rebecca M. Baus, Wei Huang, Manish S. Patankar, Nihal Ahmad
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1251.
https://doi.org/10.1158/1538-7445.AM2019-1251
Published: 01 July 2019
View article titled, Abstract 1251: Potential tumor suppressor function of polo-like kinase 5 in ovarian cancers
Journal Articles

Abstract 1332: High Throughput isolation and expansion of circulating tumor cells (CTCs) from Non-small cell lung cancer (NSCLC) patients for personalized treatments

Mina Zeinali, Maggie Lee, Arthi Nadhan, Anvya Mathur, Wei Huang, Eric Lin, Ramdane Harouaka, Max S. Wicha, Nallasivam Palanisamy, Mathias Hafner, Rishindra Reddy, Gregory P. Kalemkerian, Bryan J. Schneider, Khaled A. Hassan, Nithya Ramnath, Sunitha Nagrath
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1332.
https://doi.org/10.1158/1538-7445.AM2019-1332
Published: 01 July 2019
View article titled, Abstract 1332: High Throughput isolation and expansion of circulating tumor cells (CTCs) from Non-small cell lung cancer (NSCLC) patients for personalized treatments