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Journal Articles

Abstract 2932: GNX1021, a novel ADC targeting glycans with branched Lewis B/Y, demonstrated preclinical tumor control activity in gastric cancer models and favorable safety

Free
Yen-Ying Chen, Chia-Chun Chang, Wen-Han Lee, Ching-Kuei Chen, Ying-Rou Shen, Yu-Ting Lin, Chong-Wei He, Yu-Jeng Wang, Liang-Yirn Liu, Mei-Chun Yang, Tong-Hsuan Chang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2932.
https://doi.org/10.1158/1538-7445.AM2025-2932
Published: 21 April 2025
View articletitled, Abstract 2932: GNX1021, a novel ADC targeting glycans with branched Lewis B/Y, demonstrated preclinical tumor control activity in gastric cancer models and favorable safety
Journal Articles

Abstract 1999: DCAF7 acts as a scaffold to recruit USP10 for G3BP1 deubiquitylation and facilitates chemoresistance and metastasis in nasopharyngeal carcinoma

Free
Qing-Jie Li, Xue-Liang Fang, Ying-Qin Li, Jia-Yi Lin, Cheng-Long Huang, Shi-Wei He, Sheng-Yan Huang, Jun-Yan Li, Sha Gong, Kai-Lin Chen, Na Liu, Jun Ma, Yin Zhao, Ling-Long Tang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1999.
https://doi.org/10.1158/1538-7445.AM2024-1999
Published: 22 March 2024
View articletitled, Abstract 1999: DCAF7 acts as a scaffold to recruit USP10 for G3BP1 deubiquitylation and facilitates chemoresistance and metastasis in nasopharyngeal carcinoma
Journal Articles

Abstract 1113: USP18 impairs the sensitivity of radiotherapy for nasopharyngeal carcinoma by promoting the ubiquitination and nuclear translocation of TRIM29

Free
Jia-Yi Lin, Wei-Wei Zhang, Qing-Jie Li, Xue-Liang Fang, Jun-Yan Li, Shi-Wei He, Ying-Qin Li, Jun Ma, Na Liu, Yin Zhao, Rui Guo
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1113.
https://doi.org/10.1158/1538-7445.AM2024-1113
Published: 22 March 2024
View articletitled, Abstract 1113: USP18 impairs the sensitivity of radiotherapy for nasopharyngeal carcinoma by promoting the ubiquitination and nuclear translocation of TRIM29
Journal Articles

Abstract P4-03-09: Risk of breast cancer after false-positive mammography recalls: a matched cohort study

Free
Xinhe Mao, Wei He, Keith Humphreys, Haomin Yang, Kamila Czene
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P4-03-09.
https://doi.org/10.1158/1538-7445.SABCS22-P4-03-09
Published: 01 March 2023
View articletitled, Abstract P4-03-09: Risk of breast cancer after false-positive mammography recalls: a matched cohort study
Journal Articles

Determinants and Effectiveness of Extending the Duration of Adjuvant Hormone Therapy beyond 5 Years in Patients with Breast Cancer

Open Access
Erwei Zeng, Wei He, Arvid Sjölander, Jenny Bergqvist, Kamila Czene
Journal: Cancer Research
Cancer Res (2022) 82 (19): 3614–3621.
https://doi.org/10.1158/0008-5472.CAN-22-0900
Published: 04 October 2022
View articletitled, Determinants and Effectiveness of Extending the Duration of Adjuvant Hormone Therapy beyond 5 Years in Patients with Breast Cancer
Open the PDF for Determinants and Effectiveness of Extending the Duration of Adjuvant Hormone Therapy beyond 5 Years in Patients with Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract P3-12-04: Extending therapy after 5-year adjuvant hormone therapy in breast cancer patients: A population-based study

Free
Erwei Zeng, Wei He, Jenny Bergqvist, Kamila Czence
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-12-04.
https://doi.org/10.1158/1538-7445.SABCS21-P3-12-04
Published: 15 February 2022
View articletitled, Abstract P3-12-04: Extending therapy after 5-year adjuvant hormone therapy in breast cancer patients: A population-based study
Journal Articles

Abstract P4-04-03: Modulation of antitumor immunity by extracellular matrix environment in vitro

Free
Claire Robertson, Aimy Sebastian, Aubree Hinckley, Naiomy Rios-Arce, William Hynes, Wei He, Nicholas Hum, Elizabeth Wheeler, Matthew Coleman, Moniva Moya
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P4-04-03.
https://doi.org/10.1158/1538-7445.SABCS21-P4-04-03
Published: 15 February 2022
View articletitled, Abstract P4-04-03: Modulation of antitumor immunity by extracellular matrix environment in vitro
Journal Articles

Abstract PS7-02: The relationship of established breast cancer risk factors with breast cancer subtypes

Free
Anne Marie McCarthy, Tara Friebel, Wei He, Michaela Welch, Sarah Ehsan, Kevin Hughes, Alan Semine, Jinbo Chen, Despina Kontos, Susan Domchek, Emily Conant, Aditya Bardia, Constance Lehman, Katrina Armstrong
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS7-02.
https://doi.org/10.1158/1538-7445.SABCS20-PS7-02
Published: 15 February 2021
View articletitled, Abstract PS7-02: The relationship of established breast cancer risk factors with breast cancer subtypes
Journal Articles

Abstract PS18-09: Novel chimeric small molecule AC682 potently degrades estrogen receptor with oral anti-tumor efficacy superior to fulvestrant

Free
Wei He, Hui Zhang, Lorena Perkins, Lissette Bouza, Ke Liu, Yimin Qian, Jie Fan
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS18-09.
https://doi.org/10.1158/1538-7445.SABCS20-PS18-09
Published: 15 February 2021
View articletitled, Abstract PS18-09: Novel chimeric small molecule AC682 potently degrades estrogen receptor with oral anti-tumor efficacy superior to fulvestrant
Journal Articles

Heritability of Mammographic Breast Density, Density Change, Microcalcifications, and Masses

Available to Purchase
Natalie Holowko, Mikael Eriksson, Ralf Kuja-Halkola, Shadi Azam, Wei He, Per Hall, Kamila Czene
Journal: Cancer Research
Cancer Res (2020) 80 (7): 1590–1600.
https://doi.org/10.1158/0008-5472.CAN-19-2455
Published: 02 April 2020
View articletitled, Heritability of Mammographic Breast Density, Density Change, Microcalcifications, and Masses
Open the PDF for Heritability of Mammographic Breast Density, Density Change, Microcalcifications, and Masses in another window
Includes: Supplementary data
Journal Articles

Abstract PD2-08: Gene expression analysis and association with treatment response in postmenopausal patients with hormone receptor-positive, HER2-negative advanced breast cancer in the MONALEESA-3 study

Free
Stephen Chia, Faye Su, Patrick Neven, Seock-Ah Im, Katarina Petrakova, Giulia Val Bianchi, Wei He, Karen Rodriguez-Lorenc, Tetiana Taran, Naveen Babbar, Dennis Slamon
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): PD2-08.
https://doi.org/10.1158/1538-7445.SABCS19-PD2-08
Published: 15 February 2020
View articletitled, Abstract PD2-08: Gene expression analysis and association with treatment response in postmenopausal patients with hormone receptor-positive, HER2-negative advanced breast cancer in the MONALEESA-3 study
Journal Articles

Abstract CT143: Baseline circulating tumor DNA (ctDNA) analysis in Asian women with HR+/HER2- advanced breast cancer (ABC) receiving ribociclib + endocrine therapy in the Phase Ib MONALEESASIA trial

Free
Yoon-Sim Yap, Faye Su, Nadia Solovieff, Yoshinori Ito, Norikaza Masuda, Takashi Ishikawa, Tomoyuki Aruga, Seung Jin Kim, Wei He, Mihaela Gazdoiu, Joanne Chiu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT143.
https://doi.org/10.1158/1538-7445.AM2019-CT143
Published: 01 July 2019
View articletitled, Abstract CT143: Baseline circulating tumor DNA (ctDNA) analysis in Asian women with HR+/HER2- advanced breast cancer (ABC) receiving ribociclib + endocrine therapy in the Phase Ib MONALEESASIA trial
Journal Articles

Abstract CT142: Prevalence of PIK3CAmutations in patients with hormone receptor-positive, human epidermal growth factor-2-negative advanced breast cancer from the SOLAR-1 trial

Free
Hope S. Rugo, Ingrid Mayer, Pierfranco Conte, Sibylle Loibl, Mario Campone, Dejan Juric, Fabrice Andre, Marilyn Fritzemeier, Wei He, Naveen Babbar, Eva Ciruelos
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT142.
https://doi.org/10.1158/1538-7445.AM2019-CT142
Published: 01 July 2019
View articletitled, Abstract CT142: Prevalence of PIK3CAmutations in patients with hormone receptor-positive, human epidermal growth factor-2-negative advanced breast cancer from the SOLAR-1 trial
Journal Articles

Abstract 37: RNA-seq comparisons of in vitro and in vivo cancer model platforms: Monolayer, spheroids, immunodeficient, and syngeneic mouse model

Free
Nicholas Hum, Aimy Sebastian, Wei He, Monica L. Moya, William F. Hynes, Jonathan J. Adorno, Aubree Hinckley, Elizabeth K. Wheeler, Matthew A. Coleman, Gabriela G. Loots
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 37.
https://doi.org/10.1158/1538-7445.AM2019-37
Published: 01 July 2019
View articletitled, Abstract 37: RNA-seq comparisons of in vitro and in vivo cancer model platforms: Monolayer, spheroids, immunodeficient, and syngeneic mouse model
Journal Articles

Abstract 674: Predicting cellular response to therapy in breast cancer using mathematical modeling

Free
Wei He, Diane M. Demas, Isabel Conde, Yassi Fallah, William T. Baumann, Ayesha N. Shajahan-Haq
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 674.
https://doi.org/10.1158/1538-7445.AM2019-674
Published: 01 July 2019
View articletitled, Abstract 674: Predicting cellular response to therapy in breast cancer using mathematical modeling
Journal Articles

Abstract 2528: Determining gene expression variability between in vitro and in vivo cancer models: Monolayer, spheroids, and mouse allografts

Free
Nicholas R. Hum, Wei He, Aimy Sebastian, Elizabeth K. Wheeler, Matthew A. Coleman, Gabriela G. Loots
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2528.
https://doi.org/10.1158/1538-7445.AM2018-2528
Published: 01 July 2018
View articletitled, Abstract 2528: Determining gene expression variability between in vitro and in vivo cancer models: Monolayer, spheroids, and mouse allografts
Journal Articles

Abstract CT069: Baseline gene expression patterns of CDK4/6 inhibitor-naïve or -refractory HR+, HER2- advanced breast cancer in the phase Ib study of ribociclib plus everolimus plus exemestane

Free
Aditya Bardia, Shanu Modi, Javier Cortes, Mario Campone, Luc Dirix, Brigette Ma, J Thaddeus Beck, Jorge Chaves, Amy Weise, Jacqueline Vuky, Gilberto Lopes, Miguel Gil-Gil, Xiaochun Liu, Wei He, Faye Su, Michelle Miller, Mariana Chavez-MacGregor
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT069.
https://doi.org/10.1158/1538-7445.AM2018-CT069
Published: 01 July 2018
View articletitled, Abstract CT069: Baseline gene expression patterns of CDK4/6 inhibitor-naïve or -refractory HR+, HER2- advanced breast cancer in the phase Ib study of ribociclib plus everolimus plus exemestane
Journal Articles

Abstract CT045: Ribociclib + letrozole for first-line treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced breast cancer (ABC): efficacy by baseline tumor markers

Free
Fabrice Andre, Salomon M. Stemmer, Mario Campone, Katarina Petrakova, Shani Paluch-Shimon, Yoon-Sim Yap, Norbert Marschner, Arlene Chan, Cristian Villanueva, Lowell L. Hart, Carlos L. Arteaga, Gabe S. Sonke, Eva-Maria Grischke, Emilio Alba, Arnd Nusch, Denise A. Yardley, Erik Jakobsen, Sibel Blau, Sara M. Tolaney, Faye Su, Wei He, Caroline Germa, Gabriel N. Hortobagyi
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT045.
https://doi.org/10.1158/1538-7445.AM2017-CT045
Published: 01 July 2017
View articletitled, Abstract CT045: Ribociclib + letrozole for first-line treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced breast cancer (ABC): efficacy by baseline tumor markers
Journal Articles

Abstract 3333: In vitro-based biochemical studies of erbb2 gene variation to address racial disparities in breast cancer mortality

Free
Wei He, Matthew Saldana, Tiffany Scharadin, Steven Hoang-Phou, Denise Trans, Dennis Chang, Kermit Carraway, Paul Henderson, Matthew A. Coleman
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3333.
https://doi.org/10.1158/1538-7445.AM2014-3333
Published: 01 October 2014
View articletitled, Abstract 3333: In vitro-based biochemical studies of erbb2 gene variation to address racial disparities in breast cancer mortality
Journal Articles

Abstract 3321: Using NLPs to study EGFR structure, activation, and inhibition

Free
Tiffany M. Scharadin, Matthew Saldana, Michael Schlein, Steven Hoang-Phou, Denise Trans, Dennis Chang, Wei He, Kit Lam, Kermit L. Carraway, Matthew A. Coleman, Paul T. Henderson
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3321.
https://doi.org/10.1158/1538-7445.AM2014-3321
Published: 01 October 2014
View articletitled, Abstract 3321: Using NLPs to study EGFR structure, activation, and inhibition