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Journal Articles

Abstract 594: ORIC-613, a potential first- and best-in-class, orally bioavailable, potent and selective PLK4 inhibitor with synthetic lethality in TRIM37 high cancer models

Kyle A. Edgar, Siobhan McRee, Gina Andretta, Chelsea Chen, Christophe Colas, Wei Fang, Wayne Kong, Jason Long, Fang Liu, Jared Moore, Aleskandr Pankov, Dan Shore, Joanne Tan, Robert Warne, Livia Ulicna, Rakesh Vekariya, Anneleen Daemen, F Romero, Melissa R. Junttila, Lori S. Friedman
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 594.
https://doi.org/10.1158/1538-7445.AM2024-594
Published: 22 March 2024
View article titled, Abstract 594: ORIC-613, a potential first- and best-in-class, orally bioavailable, potent and selective PLK4 inhibitor with synthetic lethality in TRIM37 high cancer models
Journal Articles

Abstract 2633: Discovery of novel, highly selective inhibitors of PLK4 that demonstrate in vivo regressions in TRIM37 high xenografts

Kyle A. Edgar, Amy Young, Jared Moore, Xi Chen, Wei Fang, Jae H. Chang, Wayne Kong, Jason E. Long, Aleksandr Pankov, Anneleen Daemen, Daniel G. Shore, Robert Warne, Paul Gibbons, Chudi O. Ndubaku, Melissa R. Junttila, Lori S. Friedman
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2633.
https://doi.org/10.1158/1538-7445.AM2022-2633
Published: 15 June 2022
View article titled, Abstract 2633: Discovery of novel, highly selective inhibitors of PLK4 that demonstrate <em>in vivo</em> regressions in TRIM37 high xenografts
Journal Articles

Abstract 2283: A novel GUCY2C - CD3 bispecific engages T cells to induce cytotoxicity in gastrointestinal tumors

Divya Mathur, Adam Root, Bozena Bugaj-Gaweda, Xingzhi Tan, Wei Fang, Stephanie Bisulco, Jonathan Golas, Diane Fernandez, Jessica Kearney, Eric Upeslacis, Johnny Yao, Edward Rosfjord, Chad Stevens, Keith Kobylarz, Lindsay King, Jatin Narula, Kerry Kelleher, David Schaer, Cris Kamperschroer, Bernard Buetow, Cynthia Rohde, Allison Moreau, Gilbert Wong, Puja Sapra
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2283.
https://doi.org/10.1158/1538-7445.AM2020-2283
Published: 15 August 2020
View article titled, Abstract 2283: A novel GUCY2C - CD3 bispecific engages T cells to induce cytotoxicity in gastrointestinal tumors
Journal Articles

Abstract SY37-02: Ligand-directed degradation of GSPT1 by a novel cereblon modulator drives potent antitumor effects

Mary Matyskiela, Gang Lu, Takumi Ito, Barbra Pagarigan, Chin-Chu Lu, Karen Miller, Wei Fang, Nai-Yu Wang, Derek Nguyen, Jack Houston, Gilles Carmel, Tam Tran, Mariko Riley, Lyn'Al Nosaka, Gabriel Lander, Svetlana Gaidarova, Shuichan Xu, Alexander Ruchelman, Hiroshi Handa, James Carmichale, Thomas O. Daniel, Brian E. Cathers, Antonia Lopez-Girona, Philip Chamberlain
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): SY37-02.
https://doi.org/10.1158/1538-7445.AM2017-SY37-02
Published: 01 July 2017
View article titled, Abstract SY37-02: Ligand-directed degradation of GSPT1 by a novel cereblon modulator drives potent antitumor effects
Journal Articles

Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss

Lee Ann Jolly, Sergey Novitskiy, Phillip Owens, Nicole Massoll, Nikki Cheng, Wei Fang, Harold L. Moses, Aime T. Franco
Journal: Cancer Research
Cancer Res (2016) 76 (7): 1804–1813.
https://doi.org/10.1158/0008-5472.CAN-15-2351
Published: 31 March 2016
View article titled, Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by Braf<sup>V600E</sup> and Pten Loss
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Includes: Supplementary data
Journal Articles

Interactions of EphA2 and HER2 promote tumor progression and anti-HER2 resistance

Guanglei Zhuang, Dana Brantley-Sieders, Donna Hicks, Wei Fang, Yoonha Hwang, Jin Chen
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 122.
Published: 01 May 2008
View article titled, Interactions of EphA2 and HER2 promote tumor progression and anti-HER2 resistance
Journal Articles

A Susceptibility Locus at Chromosome 3p21 Linked to Familial Nasopharyngeal Carcinoma

Wei Xiong, Zhao Yang Zeng, Jia Hui Xia, Kun Xia, Shou Rong Shen, Xiao Ling Li, Dong Xu Hu, Chen Tan, Juan Juan Xiang, Jie Zhou, Hao Deng, Song Qing Fan, Wei Fang Li, Rong Wang, Ming Zhou, Shi Guo Zhu, Hong Bin Lü, Jun Qian, Bi Cheng Zhang, Jie Ru Wang, Jian Ma, Bing Yi Xiao, He Huang, Qiu Hong Zhang, Yan Hong Zhou, Xiao Min Luo, Hou De Zhou, Yi Xin Yang, He Ping Dai, Guo Yin Feng, Qian Pan, Ling Qian Wu, Lin He, Gui Yuan Li
Journal: Cancer Research
Cancer Res (2004) 64 (6): 1972–1974.
https://doi.org/10.1158/0008-5472.CAN-03-3253
Published: 16 March 2004
View article titled, A Susceptibility Locus at Chromosome 3p21 Linked to Familial Nasopharyngeal Carcinoma
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Journal Articles

Hypermethylation in Human Cancers of the RIZ1 Tumor Suppressor Gene, a Member of a Histone/Protein Methyltransferase Superfamily

Yong Du, Tobias Carling, Wei Fang, Zhe Piao, Jin-Chuan Sheu, Shi Huang
Journal: Cancer Research
Cancer Res (2001) 61 (22): 8094–8099.
Published: 01 November 2001
View article titled, Hypermethylation in Human Cancers of the <em>RIZ1</em> Tumor Suppressor Gene, a Member of a Histone/Protein Methyltransferase Superfamily
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Journal Articles

Frequent Frameshift Mutations of RIZ in Sporadic Gastrointestinal and Endometrial Carcinomas with Microsatellite Instability

Zhe Piao, Wei Fang, Sergei Malkhosyan, Hoguen Kim, Akira Horii, Manuel Perucho, Shi Huang
Journal: Cancer Research
Cancer Res (2000) 60 (17): 4701–4704.
Published: 01 September 2000
View article titled, Frequent Frameshift Mutations of <em>RIZ</em> in Sporadic Gastrointestinal and Endometrial Carcinomas with Microsatellite Instability
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Journal Articles

Tyrosine Phosphorylation Is Required for Up-Regulation of the HOX-11 (TCL-3) Homeobox Proto-oncogene in T Cells

Nan Zhang, Wei-fang Shen, Anthony D. Ho, Ming Lu
Journal: Cancer Research
Cancer Res (1995) 55 (5): 1117–1121.
Published: 01 March 1995
View article titled, Tyrosine Phosphorylation Is Required for Up-Regulation of the <em>HOX-11 (TCL-3)</em> Homeobox Proto-oncogene in T Cells
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Journal Articles

Stimulation of Malignant Growth in Rodents by Antidepressant Drugs at Clinically Relevant Doses

Lorne J. Brandes, Randi J. Arron, R. Patricia Bogdanovic, Jiangang Tong, Cheryl L. F. Zaborniak, Georgina R. Hogg, Robert C. Warrington, Wei Fang, Frank S. LaBella
Journal: Cancer Research
Cancer Res (1992) 52 (13): 3796–3800.
Published: 01 July 1992
View article titled, Stimulation of Malignant Growth in Rodents by Antidepressant Drugs at Clinically Relevant Doses
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