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Warren Hurlburt
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Journal Articles

Differential Mechanisms of Acquired Resistance to Insulin-like Growth Factor-I Receptor Antibody Therapy or to a Small-Molecule Inhibitor, BMS-754807, in a Human Rhabdomyosarcoma Model

Fei Huang, Warren Hurlburt, Ann Greer, Karen A. Reeves, Stephen Hillerman, Han Chang, Joseph Fargnoli, Friedrich Graf Finckenstein, Marco M. Gottardis, Joan M. Carboni
Journal: Cancer Research
Cancer Res (2010) 70 (18): 7221–7231.
https://doi.org/10.1158/0008-5472.CAN-10-0391
Published: 14 September 2010
View article titled, Differential Mechanisms of Acquired Resistance to Insulin-like Growth Factor-I Receptor Antibody Therapy or to a Small-Molecule Inhibitor, BMS-754807, in a Human Rhabdomyosarcoma Model
Open the PDF for Differential Mechanisms of Acquired Resistance to Insulin-like Growth Factor-I Receptor Antibody Therapy or to a Small-Molecule Inhibitor, BMS-754807, in a Human Rhabdomyosarcoma Model in another window
Includes: Supplementary data
Journal Articles

Abstract 363: Therapeutic targeting of insulin receptor-A with a dual IGF-1R/IR inhibitor: Overcoming a potential escape mechanism from IGF-1R-specific signaling inhibition in insulin receptor-A transfected cancer cells

Stephen M. Hillerman, Ann F. Greer, Warren Hurlburt, Fei Huang, Karen Reeves, Rolf Ryseck, Friedrich Graf Finckenstein, Arindam Dhar, Robert A. Kramer, Marco M. Gottardis, Joan M. Carboni
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 363.
https://doi.org/10.1158/1538-7445.AM10-363
Published: 15 April 2010
View article titled, Abstract 363: Therapeutic targeting of insulin receptor-A with a dual IGF-1R/IR inhibitor: Overcoming a potential escape mechanism from IGF-1R-specific signaling inhibition in insulin receptor-A transfected cancer cells
Journal Articles

The Mechanisms of Differential Sensitivity to an Insulin-like Growth Factor-1 Receptor Inhibitor (BMS-536924) and Rationale for Combining with EGFR/HER2 Inhibitors

Fei Huang, Ann Greer, Warren Hurlburt, Xia Han, Rameh Hafezi, Gayle M. Wittenberg, Karen Reeves, Jiwen Chen, Douglas Robinson, Aixin Li, Francis Y. Lee, Marco M. Gottardis, Edwin Clark, Lee Helman, Ricardo M. Attar, Ashok Dongre, Joan M. Carboni
Journal: Cancer Research
Cancer Res (2009) 69 (1): 161–170.
https://doi.org/10.1158/0008-5472.CAN-08-0835
Published: 31 December 2008
View article titled, The Mechanisms of Differential Sensitivity to an Insulin-like Growth Factor-1 Receptor Inhibitor (BMS-536924) and Rationale for Combining with EGFR/HER2 Inhibitors
Open the PDF for The Mechanisms of Differential Sensitivity to an Insulin-like Growth Factor-1 Receptor Inhibitor (BMS-536924) and Rationale for Combining with EGFR/HER2 Inhibitors in another window
Includes: Supplementary data
Journal Articles

Preclinical evaluation of a small molecule inhibitor of the IGF-1/insulin receptor kinases in prostate cancer

Ricardo Attar, Joan Carboni, Janet Dell-John, Ann Greer, Donald Hawken, Warren Hurlburt, Maria Jure-Kunkel, Frank Lee, Liang Schweizer, Marco Gottardis, Becky Penhallow, Cheryl Rizzo, Thomas Spires, Mark Wittman
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4471.
Published: 01 May 2007
View article titled, Preclinical evaluation of a small molecule inhibitor of the IGF-1/insulin receptor kinases in prostate cancer
Journal Articles

Tumor Development by Transgenic Expression of a Constitutively Active Insulin-Like Growth Factor I Receptor

Joan M. Carboni, Adrian V. Lee, Darryl L. Hadsell, Bruce R. Rowley, Francis Y. Lee, David K. Bol, Amy E. Camuso, Marco Gottardis, Ann F. Greer, Ching Ping Ho, Warren Hurlburt, Aixin Li, Mark Saulnier, Upender Velaparthi, Cindy Wang, Mei-Li Wen, Richard A. Westhouse, Mark Wittman, Kurt Zimmermann, Brent A. Rupnow, Tai W. Wong
Journal: Cancer Research
Cancer Res (2005) 65 (9): 3781–3787.
https://doi.org/10.1158/0008-5472.CAN-04-4602
Published: 02 May 2005
View article titled, Tumor Development by Transgenic Expression of a Constitutively Active Insulin-Like Growth Factor I Receptor
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Journal Articles

BMS-536924, a potent, small molecule inhibitor of the IGF-1 receptor in vitro and in vivo

Joan M. Carboni, Mark Wittman, Ricardo Attar, Praveen Balimane, Stephen Castaneda, Janet Dell, Marco Gottardis, Ann Greer, Ching-Ping Ho, Chen-Yi Hung, Warren Hurlburt, Ivan Inigo, David Kan, Francis Y. Lee, Aixin Li, Tai-An Lin, Becky Penhallow, Mark Saulnier, Upender Velaparthi, Zheng Yang, Kurt Zimmermann
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1406.
Published: 01 May 2005
View article titled, BMS-536924, a potent, small molecule inhibitor of the IGF-1 receptor <em>in vitro</em> and <em>in vivo</em>