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Wan L. Lam
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Journal Articles

Abstract A21: MiR-106a and miR-106b affect growth and metastasis of lung adenocarcinoma

Katey SS Enfield, David A. Rowbotham, Alice Holly, Christine Anderson, Kevin W. Ng, Brenda de Carvalho Minatel, Graham Dellaire, Chiara Pastrello, Igor Jurisica, Calum MacAulay, Stephen Lam, Wan L. Lam
Journal: Cancer Research
Cancer Res (2016) 76 (6_Supplement): A21.
https://doi.org/10.1158/1538-7445.NONRNA15-A21
Published: 13 May 2016
View article titled, Abstract A21: MiR-106a and miR-106b affect growth and metastasis of lung adenocarcinoma
Journal Articles

A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets

Ayumu Taguchi, Allen D. Taylor, Jaime Rodriguez, Müge Çeliktaş, Hui Liu, Xiaotu Ma, Qing Zhang, Chee-Hong Wong, Alice Chin, Luc Girard, Carmen Behrens, Wan L. Lam, Stephen Lam, John D. Minna, Ignacio I. Wistuba, Adi F. Gazdar, Samir M. Hanash
Journal: Cancer Research
Cancer Res (2014) 74 (17): 4694–4705.
https://doi.org/10.1158/0008-5472.CAN-13-3725
Published: 01 September 2014
View article titled, A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets
Open the PDF for A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets in another window
Includes: Supplementary data
Journal Articles

YEATS4 Is a Novel Oncogene Amplified in Non–Small Cell Lung Cancer That Regulates the p53 Pathway

Larissa A. Pikor, William W. Lockwood, Kelsie L. Thu, Emily A. Vucic, Raj Chari, Adi F. Gazdar, Stephen Lam, Wan L. Lam
Journal: Cancer Research
Series: Author Choice
Cancer Res (2013) 73 (24): 7301–7312.
https://doi.org/10.1158/0008-5472.CAN-13-1897
Published: 16 December 2013
View article titled, YEATS4 Is a Novel Oncogene Amplified in Non–Small Cell Lung Cancer That Regulates the p53 Pathway
Open the PDF for YEATS4 Is a Novel Oncogene Amplified in Non–Small Cell Lung Cancer That Regulates the p53 Pathway in another window
Includes: Supplementary data
Journal Articles

Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell–like Properties in Cancer Cells

Kazuhiko Shien, Shinichi Toyooka, Hiromasa Yamamoto, Junichi Soh, Masaru Jida, Kelsie L. Thu, Shinsuke Hashida, Yuho Maki, Eiki Ichihara, Hiroaki Asano, Kazunori Tsukuda, Nagio Takigawa, Katsuyuki Kiura, Adi F. Gazdar, Wan L. Lam, Shinichiro Miyoshi
Journal: Cancer Research
Series: Author Choice
Cancer Res (2013) 73 (10): 3051–3061.
https://doi.org/10.1158/0008-5472.CAN-12-4136
Published: 12 May 2013
View article titled, Acquired Resistance to EGFR Inhibitors Is Associated with a Manifestation of Stem Cell–like Properties in Cancer Cells
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Includes: Supplementary data
Journal Articles

Abstract 4460: Acquisition of stem cell-like properties during acquired resistance to epidermal growth factor receptor inhibitors.

Kazuhiko Shien, Shinichi Toyooka, Hiromasa Yamamoto, Junichi Soh, Kelsie L. Thu, Shinsuke Hashida, Yuho Maki, Eiki Ichihara, Hiroaki Asano, Kazunori Tsukuda, Nagio Takigawa, Katsuyuki Kiura, Adi F. Gazdar, Wan L. Lam, Shinichiro Miyoshi
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4460.
https://doi.org/10.1158/1538-7445.AM2013-4460
Published: 15 April 2013
View article titled, Abstract 4460: Acquisition of stem cell-like properties during acquired resistance to epidermal growth factor receptor inhibitors.
Journal Articles

Abstract B21: The paralogous microRNA clusters, miR-17-92 and miR-106-25, are specifically overexpressed in metastatic non-small cell lung carcinomas

Katey SS Enfield, Stephen Lam, Wan L. Lam
Journal: Cancer Research
Cancer Res (2012) 72 (2_Supplement): B21.
https://doi.org/10.1158/1538-7445.NONRNA12-B21
Published: 03 April 2013
View article titled, Abstract B21: The paralogous microRNA clusters, <em>miR-17-92</em> and <em>miR-106-25</em>, are specifically overexpressed in metastatic non-small cell lung carcinomas
Journal Articles

Abstract 2966: Amplification and activation of GATA6 sustain oncogenic lineage-survival in esophageal adenocarcinoma

Lin Lin, Adam J. Bass, William W. Lockwood, Zhuwen Wang, Amy L. Silvers, Dafydd G. Thomas, Andrew C. Chang, Jules Lin, Mark B. Orringer, Weiquan Li, Thomas W. Glover, Thomas J. Giordano, Wan L. Lam, Matthew L. Meyerson, David G. Beer
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2966.
https://doi.org/10.1158/1538-7445.AM2012-2966
Published: 15 April 2012
View article titled, Abstract 2966: Amplification and activation of <em>GATA6</em> sustain oncogenic lineage-survival in esophageal adenocarcinoma
Journal Articles

Abstract 4703: Mitochondrial DNA mutations affect respiratory complex-I in never-smoker lung cancer patients and contribute to lung cancer cell growth

Santanu Dasgupta, Ethan Soudry, Chunbo Shao, Nitai D. Mukhopadhyay, John Yee, Stephen Lam, Wan L. Lam, Paul B. Fisher, David Sidransky
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4703.
https://doi.org/10.1158/1538-7445.AM2011-4703
Published: 15 April 2011
View article titled, Abstract 4703: Mitochondrial DNA mutations affect respiratory complex-I in never-smoker lung cancer patients and contribute to lung cancer cell growth
Journal Articles

Abstract LB-346: A novel lung tumor suppressor implicated in somatic and familial cancers

Ian M. Wilson, Katey S. S. Enfield, Emily A. Vucic, Raj Chari, Yu-An Zhang, Ming You, Calum MacAulay, Stephen Lam, Adi Gazdar, Wan L. Lam
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): LB-346.
https://doi.org/10.1158/1538-7445.AM10-LB-346
Published: 15 April 2010
View article titled, Abstract LB-346: A novel lung tumor suppressor implicated in somatic and familial cancers
Journal Articles

Abstract 240: Amplification status of GAS41 and MDM2 in lung adenocarcinomas

Larissa Pikor, William W. Lockwood, Emily A. Vucic, Wan L. Lam
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 240.
https://doi.org/10.1158/1538-7445.AM10-240
Published: 15 April 2010
View article titled, Abstract 240: Amplification status of GAS41 and MDM2 in lung adenocarcinomas
Journal Articles

PIK3CA Mutations and Copy Number Gains in Human Lung Cancers

Hiromasa Yamamoto, Hisayuki Shigematsu, Masaharu Nomura, William W. Lockwood, Mitsuo Sato, Naoki Okumura, Junichi Soh, Makoto Suzuki, Ignacio I. Wistuba, Kwun M. Fong, Huei Lee, Shinichi Toyooka, Hiroshi Date, Wan L. Lam, John D. Minna, Adi F. Gazdar
Journal: Cancer Research
Cancer Res (2008) 68 (17): 6913–6921.
https://doi.org/10.1158/0008-5472.CAN-07-5084
Published: 28 August 2008
View article titled, <em>PIK3CA</em> Mutations and Copy Number Gains in Human Lung Cancers
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Includes: Supplementary data
Journal Articles

Comment re: A Comparison of DNA Copy Number Profiling Platforms

Bradley P. Coe, Calum MacAulay, Wan L. Lam, Bauke Ylstra, Beatriz Carvalho, Gerrit A. Meijer
Journal: Cancer Research
Cancer Res (2008) 68 (10): 4010.
https://doi.org/10.1158/0008-5472.CAN-07-6439
Published: 15 May 2008
View article titled, Comment re: A Comparison of DNA Copy Number Profiling Platforms
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Journal Articles

Comprehensive serial analysis of gene expression of the cervical epithelium transcriptome

Ashleen Shadeo, Raj Chari, Calum MacAulay, Wan L Lam
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 3715.
Published: 01 May 2007
View article titled, Comprehensive serial analysis of gene expression of the cervical epithelium transcriptome
Journal Articles

Array CGH coupled with expression profiling identifies disruption of different pathways between small and non-small cell lung carcinoma cell lines

Bradley P. Coe, William W. Lockwood, Luc Girard, Raj Chari, Calum Macaulay, Stephen Lam, Adi F. Gazdar, John D. Minna, Wan L. Lam
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 38.
Published: 15 April 2006
View article titled, Array CGH coupled with expression profiling identifies disruption of different pathways between small and non-small cell lung carcinoma cell lines
Journal Articles

Serial analysis of gene expression in preinvasive cervical cancer

Ashleen Shadeo, Kim M. Lonergan, Raj Chari, Calum Macaulay, Wan L. Lam
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 719.
Published: 15 April 2006
View article titled, Serial analysis of gene expression in preinvasive cervical cancer
Journal Articles

A comprehensive and interactive array comparative genomic hybridization database for cancer genomes

Raj Chari, William W. Lockwood, Bradley P. Coe, Calum Macaulay, Wan L. Lam
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 616.
Published: 15 April 2006
View article titled, A comprehensive and interactive array comparative genomic hybridization database for cancer genomes
Journal Articles

The contribution of gene amplification to the activation of oncogenes in cancer genomes

William W. Lockwood, Bradley P. Coe, Raj Chari, Calum Macaulay, Wan L. Lam
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 601.
Published: 15 April 2006
View article titled, The contribution of gene amplification to the activation of oncogenes in cancer genomes
Journal Articles

Comparative genomic profiling of bronchioloalveolar carcinoma and invasive adenocarcinoma by array-CGH

Sarit Aviel-Ronen, Bradley P. Coe, Wan L. Lam, Ming-Sound Tsao
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 613.
Published: 15 April 2006
View article titled, Comparative genomic profiling of bronchioloalveolar carcinoma and invasive adenocarcinoma by array-CGH
Journal Articles

Whole genome tiling path array CGH analysis localizes breakpoints corresponding to HPV integration sites in cervical carcinoma genomes

William W. Lockwood, Bradley P. Coe, Ariane C. Williams, Stephen Lam, Calum Macaulay, Wan L. Lam
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 602.
Published: 15 April 2006
View article titled, Whole genome tiling path array CGH analysis localizes breakpoints corresponding to HPV integration sites in cervical carcinoma genomes
Journal Articles

Genome-wide identification of novel regions of DNA copy number alterations in natural killer cell lymphoma by array comparative genomic hybridization

Ivy F. Tsui, Javeed Iqbal, Ronald J. Deleeuw, Gopesh Srivastava, Norio Shimizu, Wing C. Chan, Wan L. Lam
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 613–614.
Published: 15 April 2006
View article titled, Genome-wide identification of novel regions of DNA copy number alterations in natural killer cell lymphoma by array comparative genomic hybridization