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Walter J. Urba
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Journal Articles

Abstract 6707: Direct in vivo CRISPR screen identifies BAP1 and FAT1 as potent tumor suppressors in sarcomagenesis

Free
Jianguo Huang, Xingliang Liu, Warren Floyd, William Haugh, Andrea R. Daniel, Zhaoyu Sun, Nerissa T. Williams, Melissa J. Kasiewicz, Yaping Wu, Diana M. Cardona, Brian Piening, John T. Welle, Wesley K. Rosales, Venkatesh Rajamanickam, So Young Kim, Eric Xu, Lixia Luo, Yan Ma, Kristianne M. Oristian, Omar Lopez, Nicholas E. Sibinga, Rutulkumar Patel, Ziqiang Zhang, Alexander J. Lazar, Corinne M. Linardic, Brady Bernard, William L. Redmond, Walter J. Urba, David G. Kirsch
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 6707.
https://doi.org/10.1158/1538-7445.AM2025-6707
Published: 21 April 2025
View articletitled, Abstract 6707: Direct in vivo CRISPR screen identifies BAP1 and FAT1 as potent tumor suppressors in sarcomagenesis
Journal Articles

Abstract A025: Direct in vivo CRISPR screen identifies BAP1 and FAT1 as potent tumor suppressors in sarcomagenesis

Free
Jianguo Huang, Xingliang Liu, Warren Floyd, William Haugh, Andrea R Daniel, Zhaoyu Sun, Nerissa T Williams, Melissa J Kasiewicz, Yaping Wu, Diana M Cardona, Brian Piening, John T. Welle, Wesley K Rosales, Venkatesh Rajamanickam, So Young Kim, Eric Xu, Lixia Luo, Yan Ma, Kristianne M Oristian, Omar Lopez, Nicholas E. S. Sibinga, Rutulkumar Patel, Ziqiang Zhang, Alexander J Lazar, Corinne M Linardic, Brady Bernard, William L Redmond, Walter J Urba, David G Kirsch
Journal: Cancer Research
Cancer Res (2025) 85 (5_Supplement): A025.
https://doi.org/10.1158/1538-7445.GENFUNC25-A025
Published: 11 March 2025
View articletitled, Abstract A025: Direct in vivo CRISPR screen identifies BAP1 and FAT1 as potent tumor suppressors in sarcomagenesis
Journal Articles

Abstract CT112: An off-the-shelf multivalent vaccine containing cancer’s dark matter, DPV-001, combined with PD-1 +/- GITR in head & neck cancer: safety, efficacy, and immunodynamics from the phase 1 GITRVax trial

Free
Rom S. Leidner, Christopher Paustian, Shawn M. Jensen, Tarsem Moudgil, Yoshinobu Koguchi, Noah Simons, Venkatesh Rajamanickam, Ryan Meng, Marcus A. Couey, Quyen Vu, Matthew H. Taylor, Anne Long, Abigail J. Staeck, Lakhvir Kaur, Tijana Jovanovic, Brady Bernard, Tanisha Christie, Noriko Iwamoto, Yuriko Minegishi, Koji Ueda, William Redmond, Lessli M. Rushforth, Takashi Shimada, Patrick Rethwisch, Ashish Patel, Richard B. Bell, Carlo B. Bifulco, Traci L. Hilton, Hong-Ming Hu, Brian Piening, Walter J. Urba, Bernard A. Fox
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT112.
https://doi.org/10.1158/1538-7445.AM2024-CT112
Published: 05 April 2024
View articletitled, Abstract CT112: An off-the-shelf multivalent vaccine containing cancer’s dark matter, DPV-001, combined with PD-1 +/- GITR in head & neck cancer: safety, efficacy, and immunodynamics from the phase 1 GITRVax trial
Journal Articles

Abstract CT123: Trial in progress: First-in-human immunotherapy-trio for advanced head and neck squamous cell carcinoma

Free
Marcus A. Couey, Matthew Taylor, Tarsem Moudgil, Yoshinobu Koguchi, Anne Stadum, Tanisha Christie, William L. Redmond, Christopher Paustian, Ryan Meng, Venkatesh Rajamanickam, Lessli Rushforth, Abigail Peterson, Brady Bernard, Richard B. Bell, Carlo B. Bifulco, Traci L. Hilton, Shawn M. Jensen, Hong-Ming Hu, Brian Piening, Walter J. Urba, Bernard A. Fox, Rom S. Leidner
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT123.
https://doi.org/10.1158/1538-7445.AM2023-CT123
Published: 14 April 2023
View articletitled, Abstract CT123: Trial in progress: First-in-human immunotherapy-trio for advanced head and neck squamous cell carcinoma
Journal Articles

Abstract CT502: Preliminary immunological monitoring of first-in-human immunotherapy-trio for advanced head and neck squamous cell carcinoma

Free
Rom S. Leidner, Matthew H. Taylor, Tarsem L. Moudgil, Tanisha L. Christie, Yoshinobu Koguchi, Alexa Dowdell, William L. Redmond, Shawn M. Jensen, Carmen Ballesteros-Merino, Jake A. Vancampen, Venkatesh Rajamanickam, Brady M. Bernard, Christopher Paustian, Traci L. Hilton, Hong-Ming Hu, Richard B. Bell, Walter J. Urba, Carlo B. Bifulco, Brian Piening, Bernard A. Fox
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT502.
https://doi.org/10.1158/1538-7445.AM2022-CT502
Published: 15 June 2022
View articletitled, Abstract CT502: Preliminary immunological monitoring of first-in-human immunotherapy-trio for advanced head and neck squamous cell carcinoma
Journal Articles

Abstract OT1-18-04: A phase II study of dual immune checkpoint blockade (ICB) plus bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer (MBC)

Free
David B Page, Krystle L Collins, Brie Chun, Zhaoyu Sun, William L Redmond, Maritza Martel, Yaping Wu, Nicole Moxon, Staci L Mellinger, Walter J Urba, Tiffany A Traina, Ayca Gucalp
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): OT1-18-04.
https://doi.org/10.1158/1538-7445.SABCS21-OT1-18-04
Published: 15 February 2022
View articletitled, Abstract OT1-18-04: A phase II study of dual immune checkpoint blockade (ICB) plus bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer (MBC)
Journal Articles

Abstract P2-12-14: A pilot evaluation of cold-capping efficacy under real world conditions for the prevention of chemotherapy-induced alopecia in early stage breast cancer

Free
Manaz Rezayee, Alison K Conlin, Janet Ruzich, Nicole Fredrich, Amanda Y Seino, Susan Mulligan, Tracy L Kelly, Julie Cramer, Walter J Urba, David B Page
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P2-12-14.
https://doi.org/10.1158/1538-7445.SABCS19-P2-12-14
Published: 15 February 2020
View articletitled, Abstract P2-12-14: A pilot evaluation of cold-capping efficacy under real world conditions for the prevention of chemotherapy-induced alopecia in early stage breast cancer
Journal Articles

Abstract 2988: Immunogenomic analyses of tumor cells and microenvironment in patients with advanced melanoma before and after treatment with nivolumab

Free
Timothy A. Chan, Nadeem Riaz, Jonathan J. Havel, Vladimir Makarov, Alexis Desrichard, Jennifer S. Sims, F. Stephen Hodi, Salvador Martín-Algarra, William H. Sharfman, Shailender Bhatia, Wen-Jen Hwu, Thomas F. Gajewski, Craig L. Slingluff, Sviatoslav M. Kendall, Han Chang, John-William Sidhom, Jonathan P. Schneck, Nils Weinhold, Christine E. Horak, Walter J. Urba
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2988.
https://doi.org/10.1158/1538-7445.AM2017-2988
Published: 01 July 2017
View articletitled, Abstract 2988: Immunogenomic analyses of tumor cells and microenvironment in patients with advanced melanoma before and after treatment with nivolumab
Journal Articles

Abstract CT073: Immunomodulatory effects of nivolumab and ipilimumab in combination or nivolumab monotherapy in advanced melanoma patients: CheckMate 038

Free
Antoni Ribas, Salvador Martín-Algarra, Shailender Bhatia, Wen-Jen Hwu, Craig L. Slingluff, William H. Sharfman, F. Stephen Hodi, Walter J. Urba, Jason J. Luke, John B. Haanen, Margaret K. Callahan, Jedd D. Wolchok, Scott D. Chasalow, Petra Ross-Macdonald, Tina C. Young, Anila Qureshi, Christine E. Horak
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT073.
https://doi.org/10.1158/1538-7445.AM2017-CT073
Published: 01 July 2017
View articletitled, Abstract CT073: Immunomodulatory effects of nivolumab and ipilimumab in combination or nivolumab monotherapy in advanced melanoma patients: CheckMate 038
Journal Articles

Serum Immunoregulatory Proteins as Predictors of Overall Survival of Metastatic Melanoma Patients Treated with Ipilimumab

Free
Yoshinobu Koguchi, Helena M. Hoen, Shelly A. Bambina, Michael D. Rynning, Richard K. Fuerstenberg, Brendan D. Curti, Walter J. Urba, Christina Milburn, Frances Rena Bahjat, Alan J. Korman, Keith S. Bahjat
Journal: Cancer Research
Series: Author Choice
Cancer Res (2015) 75 (23): 5084–5092.
https://doi.org/10.1158/0008-5472.CAN-15-2303
Published: 30 November 2015
View articletitled, Serum Immunoregulatory Proteins as Predictors of Overall Survival of Metastatic Melanoma Patients Treated with Ipilimumab
Open the PDF for Serum Immunoregulatory Proteins as Predictors of Overall Survival of Metastatic Melanoma Patients Treated with Ipilimumab in another window
Includes: Supplementary data
Journal Articles

Abstract 2855: Immunomodulatory activity of nivolumab monotherapy in patients with advanced melanoma

Free
Walter J. Urba, Salvador Martín-Algarra, Margaret Callahan, Jedd D. Wolchok, William H. Sharfman, Jeffrey A. Sosman, Shailender Bhatia, Wen-Jen Hwu, Thomas F. Gajewski, Craig L. Slingluff, Yun Shen, Christine E. Horak, F Stephen Hodi
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2855.
https://doi.org/10.1158/1538-7445.AM2015-2855
Published: 01 August 2015
View articletitled, Abstract 2855: Immunomodulatory activity of nivolumab monotherapy in patients with advanced melanoma
Journal Articles

Abstract P5-01-12: Breast specific gamma imaging (BSGI) and breast magnetic resonance imaging (MRI): Comparison of sensitivity and specificity in women prior to breast biopsy with BIRADS 4 or 5 finding on mammography in a community setting

Free
Alison K Conlin, Nicole Moxon, Helena Hoen, Christina Gougoutas-Fox, Maureen O Baxter, Amy Weinstein, Maritza Martel, Tracy L Kelly, Walter J Urba
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P5-01-12.
https://doi.org/10.1158/1538-7445.SABCS14-P5-01-12
Published: 01 May 2015
View articletitled, Abstract P5-01-12: Breast specific gamma imaging (BSGI) and breast magnetic resonance imaging (MRI): Comparison of sensitivity and specificity in women prior to breast biopsy with BIRADS 4 or 5 finding on mammography in a community setting
Journal Articles

OX40 Is a Potent Immune-Stimulating Target in Late-Stage Cancer Patients

Free
Brendan D. Curti, Magdalena Kovacsovics-Bankowski, Nicholas Morris, Edwin Walker, Lana Chisholm, Kevin Floyd, Joshua Walker, Iliana Gonzalez, Tanisha Meeuwsen, Bernard A. Fox, Tarsem Moudgil, William Miller, Daniel Haley, Todd Coffey, Brenda Fisher, Laurie Delanty-Miller, Nicole Rymarchyk, Tracy Kelly, Todd Crocenzi, Eric Bernstein, Rachel Sanborn, Walter J. Urba, Andrew D. Weinberg
Journal: Cancer Research
Cancer Res (2013) 73 (24): 7189–7198.
https://doi.org/10.1158/0008-5472.CAN-12-4174
Published: 16 December 2013
View articletitled, OX40 Is a Potent Immune-Stimulating Target in Late-Stage Cancer Patients
Open the PDF for OX40 Is a Potent Immune-Stimulating Target in Late-Stage Cancer Patients in another window
Includes: Supplementary data
Journal Articles

Efficient Cross-presentation Depends on Autophagy in Tumor Cells

Free
Yuhuan Li, Li-Xin Wang, Guojun Yang, Fang Hao, Walter J. Urba, Hong-Ming Hu
Journal: Cancer Research
Cancer Res (2008) 68 (17): 6889–6895.
https://doi.org/10.1158/0008-5472.CAN-08-0161
Published: 28 August 2008
View articletitled, Efficient Cross-presentation Depends on Autophagy in Tumor Cells
Open the PDF for Efficient Cross-presentation Depends on Autophagy in Tumor Cells in another window
Includes: Supplementary data
Journal Articles

Cyclophosphamide treatment and reconstitution with peripheral blood mononuclear cells does not reduce the frequency of circulating FoxP3 cells in vaccinated prostate cancer patients

Free
Ilka Assmann, Daniel Haley, Tarsem Moudgil, Christian Poehlein, Hong-Ming Hu, Edwin Walker, Nathalie Sacks, Kristen Hege, Brendan Curti, Walter J. Urba, Bernard A. Fox
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 681.
Published: 15 April 2006
View articletitled, Cyclophosphamide treatment and reconstitution with peripheral blood mononuclear cells does not reduce the frequency of circulating FoxP3 cells in vaccinated prostate cancer patients
Journal Articles

Interleukin-7-Dependent Expansion and Persistence of Melanoma-Specific T Cells in Lymphodepleted Mice Lead to Tumor Regression and Editing

Free
Li-Xin Wang, Rui Li, Guojun Yang, May Lim, Aisling O'Hara, Yiwei Chu, Bernard A. Fox, Nicholas P. Restifo, Walter J. Urba, Hong-Ming Hu
Journal: Cancer Research
Cancer Res (2005) 65 (22): 10569–10577.
https://doi.org/10.1158/0008-5472.CAN-05-2117
Published: 15 November 2005
View articletitled, Interleukin-7-Dependent Expansion and Persistence of Melanoma-Specific T Cells in Lymphodepleted Mice Lead to Tumor Regression and Editing
Open the PDF for Interleukin-7-Dependent Expansion and Persistence of Melanoma-Specific T Cells in Lymphodepleted Mice Lead to Tumor Regression and Editing in another window
Journal Articles

Development of Antitumor Immune Responses in Reconstituted Lymphopenic Hosts

Free
Hong-Ming Hu, Christian H. Poehlein, Walter J. Urba, Bernard A. Fox
Journal: Cancer Research
Cancer Res (2002) 62 (14): 3914–3919.
Published: 15 July 2002
View articletitled, Development of Antitumor Immune Responses in Reconstituted Lymphopenic Hosts
Open the PDF for Development of Antitumor Immune Responses in Reconstituted Lymphopenic Hosts in another window
Journal Articles

Interstitial Pressure of Subcutaneous Nodules in Melanoma and Lymphoma Patients: Changes during Treatment

Free
Brendan D. Curti, Walter J. Urba, W. Gregory Alvord, John E. Janik, John W. Smith, II, Karen Madara, Dan L. Longo
Journal: Cancer Research
Cancer Res (1993) 53 (10): 2204–2207.
Published: 01 May 1993
View articletitled, Interstitial Pressure of Subcutaneous Nodules in Melanoma and Lymphoma Patients: Changes during Treatment
Open the PDF for Interstitial Pressure of Subcutaneous Nodules in Melanoma and Lymphoma Patients: Changes during Treatment in another window
Journal Articles

Polyinosinic-Polycytidylic Acid Complexed with Poly-l-lysine and Carboxymethylcellulose in Combination with Interleukin 2 in Patients with Cancer: Clinical and Immunological Effects1

Free
Cynthia H. Ewel, Walter J. Urba, William C. Kopp, John W. Smith, II, Ronald G. Steis, Jeffrey L. Rossio, Dan L. Longo, Mary Jane Jones, W. Gregory Alvord, Carl M. Pinsky, Joy M. Beveridge, Karen L. McNitt, Stephen P. Creekmore
Journal: Cancer Research
Cancer Res (1992) 52 (11): 3005–3010.
Published: 01 June 1992
View articletitled, Polyinosinic-Polycytidylic Acid Complexed with Poly-l-lysine and Carboxymethylcellulose in Combination with Interleukin 2 in Patients with Cancer: Clinical and Immunological Effects1
Open the PDF for Polyinosinic-Polycytidylic Acid Complexed with Poly-l-lysine and Carboxymethylcellulose in Combination with Interleukin 2 in Patients with Cancer: Clinical and Immunological Effects1 in another window
Journal Articles

Anti-CD3 Monoclonal Antibody Treatment of Patients with CD3-Negative Tumors: A Phase IA/B Study

Free
Walter J. Urba, Cynthia Ewel, William Kopp, John W. Smith, II, Ronald G. Steis, Jonathan D. Ashwell, Stephen P. Creekmore, Jeffrey Rossio, Mario Sznol, William Sharfman, Robert Fenton, John Janik, Thelma Watson, Joy Beveridge, Dan L. Longo
Journal: Cancer Research
Cancer Res (1992) 52 (9): 2394–2401.
Published: 01 May 1992
View articletitled, Anti-CD3 Monoclonal Antibody Treatment of Patients with CD3-Negative Tumors: A Phase IA/B Study
Open the PDF for Anti-CD3 Monoclonal Antibody Treatment of Patients with CD3-Negative Tumors: A Phase IA/B Study in another window