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Abstract 4048: New approach to target metastatic colorectal cancer organotropism with L-Annamycin

Rafal J. Zielinski, Krzysztof Grela Grela, Roberto Cardenas-Zuniga, Stanislaw Skora, Izabela Fokt, Edward Felix, Damian Grybowski, Waldemar Priebe

Cancer Res (2022) 82 (12_Supplement): 4048.

DOI: https://doi.org/10.1158/1538-7445.AM2022-4048

Published: 15 June 2022

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Abstract PO-066: High uptake, retention, and in vivo activity of L-Annamycin in pancreatic cancer models

Ya'an Kang, Rafal Zielinski, Roberto Cardenas Zuniga, Radjendirane Venugopal, Maria Poimenidou, Magdalena Remiszewski, Shaohua Peng, Edd Felix, Krzysztof Grela, Stanislaw Skora, Van N. Nguyen, Izabela Fokt, Waldemar Priebe

Cancer Res (2021) 81 (22_Supplement): PO-066.

DOI: https://doi.org/10.1158/1538-7445.PANCA21-PO-066

Published: 15 November 2021

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Abstract 3074: Targeting sanctuary sites of cancer: Novel approaches to treatment of lung localized tumors

Rafal Zielinski, Krzysztol Grela, Roberto Cardena Zuniga, Yaan Kang, Stanislaw Skora, Edward Felix, Julia Tuchalska-Czuron, Izabela Fokt, Waldemar Priebe

Cancer Res (2020) 80 (16_Supplement): 3074.

DOI: https://doi.org/10.1158/1538-7445.AM2020-3074

Published: 15 August 2020

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Abstract P2-15-03: Liposomal annamycin inhibition of lung localized breast cancer

Rafal Zielinski, Krzysztol Grela, Stanislaw Skora, Izabela Fokt, Matthew Sander, Adam Didluch, Waldemar Priebe

Cancer Res (2020) 80 (4_Supplement): P2-15-03.

DOI: https://doi.org/10.1158/1538-7445.SABCS19-P2-15-03

Published: 15 February 2020

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Abstract 4799: Inhibition of STAT3 in pancreatic ductal adenocarcinoma and immunotherapeutic implications

Rafal Zielinski, Izabela Fokt, Stanislaw Skora, Edward Felix, Krzysztof Grela, Jayakumar Arumugam, Radj Venugopal, Midan Ai, Genevieve Hartley, Michael Curran, Waldemar Priebe

Cancer Res (2019) 79 (13_Supplement): 4799.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4799

Published: 01 July 2019

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Abstract B091: Small-molecule inhibitors targeting a specific metabolic pathway for precision therapy of advanced castrate-resistant prostate cancer

Hirak Basu, Nathaniel Wilganowski, Jessica Lieblich, Grace Wu, Izabela Fokt, Sumankalai Ramachandran, Jiaquin Yu, Mark Titus, Waldemar Priebe, David J. Beebe, George Wilding

Cancer Res (2018) 78 (16_Supplement): B091.

DOI: https://doi.org/10.1158/1538-7445.PRCA2017-B091

Published: 14 August 2018

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Abstract 3846: A metabolic pathway targeted inhibitor for precision therapy of castrate-resistant prostate cancer

Hirak S. Basu, Nathaniel L. Wilgonowski, Jessica L. Lieblich, Grace T. Wu, Izabela Fokt, Sumankalai Ramachandran, Jiaquin Yu, Mark Titus, Waldemar Priebe, David J. Beebe, George Wilding

Cancer Res (2018) 78 (13_Supplement): 3846.

DOI: https://doi.org/10.1158/1538-7445.AM2018-3846

Published: 01 July 2018

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Journal Articles

Abstract 1927: Targeting IL-13RA2 in melanoma and pancreatic cancer

Rafal Zielinski, Izabela Tworowska, Stanislaw Skora, Aleksandra Rusin, Radjendirane Venugopal, Arumugam Jayakumar, Izabela Fokt, Yaan Kang, Jason Fleming, Yue Huang, Denise Herpai, Waldemar Debinski, Waldemar Priebe

Cancer Res (2018) 78 (13_Supplement): 1927.

DOI: https://doi.org/10.1158/1538-7445.AM2018-1927

Published: 01 July 2018

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Journal Articles

Abstract 50: 2-Deoxy-2-halo-D-glucose derivatives inhibition of glycolysis in pancreatic cancer

Rafal Zielinski, Izabela Fokt, Aleksandra Rusin, Stanislaw Skora, Waldemar Priebe

Cancer Res (2016) 76 (14_Supplement): 50.

DOI: https://doi.org/10.1158/1538-7445.AM2016-50

Published: 15 July 2016

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Abstract 3483: Synergistic combination therapy with molecular targeted drugs in glioma stem-like cells

Takashi Shingu, Lindsay Holmes, Verlene Henry, Khatri Latha, Anupama E. Gururaj, Laura A. Gibson, Tiffany Doucette, Frederick F. Lang, Ganesh Rao, Liang Yuan, Erik P. Sulman, Nicholas P. Farrell, Waldemar Priebe, Kenneth R. Hess, Yaoqi A. Wang, Jian Hu, Oliver Bogler

Cancer Res (2015) 75 (15_Supplement): 3483.

DOI: https://doi.org/10.1158/1538-7445.AM2015-3483

Published: 01 August 2015

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Abstract 4473: WP760, A new highly potent and selective agent against melanoma including BRAFi resistant melanoma

Aleksandra Rusin, Rafal Zielinski, Izabela Fokt, Van Nguyen, Stanislaw Skora, Arumugam Jayakumar, Waldemar Priebe

Cancer Res (2015) 75 (15_Supplement): 4473.

DOI: https://doi.org/10.1158/1538-7445.AM2015-4473

Published: 01 August 2015

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Journal Articles

Abstract 4540: Development of orally bioavailable formulation of WP1066 and its evaluation in vivo

Rafal Zielinski, Aleksandra Rusin, Timothy Madden, Charles Conrad, Mary Johansen, Izabela Fokt, Stanislaw Skora, Arumugam Jayakumar, Amy Heimberger, Waldemar Priebe

Cancer Res (2015) 75 (15_Supplement): 4540.

DOI: https://doi.org/10.1158/1538-7445.AM2015-4540

Published: 01 August 2015

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Abstract 2096: High sensitivity of cutaneous T-cell lymphoma (CTCL) to CABE, a component of propolis

Arumugam Jayakumar, Radjendirane Venugopal, Rafal Zielinski, Aleksandra Rusin, Izabela Fokt, Stanislaw Skora, Xiao Ni, Madeleine Duvic, Waldemar Priebe

Cancer Res (2015) 75 (15_Supplement): 2096.

DOI: https://doi.org/10.1158/1538-7445.AM2015-2096

Published: 01 August 2015

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Journal Articles

Abstract 2946: Status of STAT3, STAT5, and NF-κB in pancreatic cancer cell lines, small molecule inhibitors, and potential clinical implications

Arumugam Jayakumar, Venugopal Radjendirane, Jason Fleming, Yaan Kang, Aleksandra Rusin, Rafal Zielinski, Stanislaw Skora, Izabela Fokt, Waldemar Priebe

Cancer Res (2014) 74 (19_Supplement): 2946.

DOI: https://doi.org/10.1158/1538-7445.AM2014-2946

Published: 01 October 2014

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Journal Articles

Abstract C65: Drug-tolerant cancer cells show reduced tumor-initiating capacity: Depletion of CD44+ cells and evidence for epigenetic mechanisms

Xin Chen, Izabela Fokt, Stanislaw Skora, Waldemar Priebe, Yongyi Bi, Dean G. Tang, Hong Yan, Qiuping Zhang, Jichao Qin, Hangwen Li, Can Liu, Tammy Davis, Luis D. Coletta, Jim Klostergaard

Cancer Res (2012) 72 (4_Supplement): C65.

DOI: https://doi.org/10.1158/1538-7445.PRCA2012-C65

Published: 09 May 2013

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Journal Articles

Abstract 3251: Blockade of HIF-1 with a small molecule inhibitor WP1066 in melanoma.

Arumugam Jayakumar, Jana Rauvolfova, Hanying Bao, Izabela Fokt, Stanislaw Skora, Amy Heimberger, Waldemar Priebe

Cancer Res (2013) 73 (8_Supplement): 3251.

DOI: https://doi.org/10.1158/1538-7445.AM2013-3251

Published: 15 April 2013

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Journal Articles

Abstract LB-250: 2-Deoxy-D-glucose cytotoxicity relies on both glycolysis inhibition and ER stress induction, and is efficacious in a variety of human lymphoma models

Andrew H. Sevier, Oksana Zagorodna, Sean M. Martin, *Waldemar Priebe, C. Michael Knudson

Cancer Res (2012) 72 (8_Supplement): LB-250.

DOI: https://doi.org/10.1158/1538-7445.AM2012-LB-250

Published: 15 April 2012

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Journal Articles

Abstract 3783: Pharmacokinetics and CNS biodistribution of WP1066, a novel small molecule inhibitor of STAT-3 phosphorylation

Timothy Madden, Mary Johansen, Kirk S. Culotta, Amy Heimberger, Izabela Fokt, Charles Conrad, Waldemar Priebe

Cancer Res (2012) 72 (8_Supplement): 3783.

DOI: https://doi.org/10.1158/1538-7445.AM2012-3783

Published: 15 April 2012

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Journal Articles

Abstract 1804: Novel gold derivatives of thiosugars potently inhibit p-STAT3 and downregulate HIF-1α in ependymomas

Waldemar Priebe, Takayuki Kato, Izabela Fokt, Timothy L. Madden, Charles A. Conrad, Mary J. Johansen, Stanislaw Skora, Van N. Nguyen, Jayakumar Arumugam

Cancer Res (2012) 72 (8_Supplement): 1804.

DOI: https://doi.org/10.1158/1538-7445.AM2012-1804

Published: 15 April 2012

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Journal Articles

Abstract 2304: 2-DG inhibits of N-glycosylation in glioblastoma-derived cancer stem cells

Waldemar Priebe, Mark R. Emmett, Yongjie Ji, Izabela Fokt, Stanislaw Skora, Charles Conrad, Xu Wang, Alan G. Marshall

Cancer Res (2011) 71 (8_Supplement): 2304.

DOI: https://doi.org/10.1158/1538-7445.AM2011-2304

Published: 15 April 2011

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NARROW

Abstract 4048: New approach to target metastatic colorectal cancer organotropism with L-Annamycin

Abstract PO-066: High uptake, retention, and in vivo activity of L-Annamycin in pancreatic cancer models

Abstract 3074: Targeting sanctuary sites of cancer: Novel approaches to treatment of lung localized tumors

Abstract P2-15-03: Liposomal annamycin inhibition of lung localized breast cancer

Abstract 4799: Inhibition of STAT3 in pancreatic ductal adenocarcinoma and immunotherapeutic implications

Abstract B091: Small-molecule inhibitors targeting a specific metabolic pathway for precision therapy of advanced castrate-resistant prostate cancer

Abstract 3846: A metabolic pathway targeted inhibitor for precision therapy of castrate-resistant prostate cancer

Abstract 1927: Targeting IL-13RA2 in melanoma and pancreatic cancer

Abstract 50: 2-Deoxy-2-halo-D-glucose derivatives inhibition of glycolysis in pancreatic cancer

Abstract 3483: Synergistic combination therapy with molecular targeted drugs in glioma stem-like cells

Abstract 4473: WP760, A new highly potent and selective agent against melanoma including BRAFi resistant melanoma

Abstract 4540: Development of orally bioavailable formulation of WP1066 and its evaluation in vivo

Abstract 2096: High sensitivity of cutaneous T-cell lymphoma (CTCL) to CABE, a component of propolis

Abstract 2946: Status of STAT3, STAT5, and NF-κB in pancreatic cancer cell lines, small molecule inhibitors, and potential clinical implications

Abstract C65: Drug-tolerant cancer cells show reduced tumor-initiating capacity: Depletion of CD44+ cells and evidence for epigenetic mechanisms

Abstract 3251: Blockade of HIF-1 with a small molecule inhibitor WP1066 in melanoma.

Abstract LB-250: 2-Deoxy-D-glucose cytotoxicity relies on both glycolysis inhibition and ER stress induction, and is efficacious in a variety of human lymphoma models

Abstract 3783: Pharmacokinetics and CNS biodistribution of WP1066, a novel small molecule inhibitor of STAT-3 phosphorylation

Abstract 1804: Novel gold derivatives of thiosugars potently inhibit p-STAT3 and downregulate HIF-1α in ependymomas

Abstract 2304: 2-DG inhibits of N-glycosylation in glioblastoma-derived cancer stem cells

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