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Abstract 350: NVP-BKM120: A selective pan-PI3 kinase inhibitor induces G2/M arrest in glioma cell lines via FOXO3a and GADD45a loop

Dimpy Koul, Ruijun Shen, Tiffany A. LaFortune, Ningyi Tiao, Yong-Wan Kim, Juinn-Lin Liu, Sauveur-Michel Maira, Carlos Garcia-Echeverria, W. K. Alfred Yung

Cancer Res (2010) 70 (8_Supplement): 350.

DOI: https://doi.org/10.1158/1538-7445.AM10-350

Published: 15 April 2010

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Abstract #4800: WP1193 Inhibits JAK2/STAT3 Pathway, blocks self-renewal and induces apoptosis in glioblastoma cancer stem cells

Howard Colman, Charles Conrad, Ke Sai, Shuzhen Wang, Sonya Popoff, Ken Aldape, Fred Lang, Izabela Fokt, Timothy Madden, W. K. Alfred Yung, Waldemar Priebe

Cancer Res (2009) 69 (9_Supplement): 4800.

Published: 01 May 2009

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Journal Articles

E2F1 transcriptionally activates PTEN

Melissa Vinores Olson, Marta M. Alonso, Candelaria Gomez-Manzano, Diana R. Medrano, Xiaoyang Sheng, Hong Jiang, W. K. Alfred Yung, Juan Fueyo

Cancer Res (2005) 65 (9_Supplement): 661.

Published: 01 May 2005

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Treatment of glioma-bearing mice with VEGF Trap results in significant prolongation of survival

Candelaria Gomez-Manzano, Jocelyn Holash, Jing Xu, Ok-Hee Lee, Juan Fueyo, John Rudge, B. Nebiyou Bekele, Xian Zhou, Kenneth Aldape, W. K. Alfred Yung

Cancer Res (2005) 65 (9_Supplement): 712.

Published: 01 May 2005

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The expression of VEGF, CDK4, PAX6, EGFR, IGFBP2, PTEN, MMP2 and P53 in patients with oligodendrogliomas: Relationship to 5-year mortality

Longjian Liu, W. K. Alfred Yung, Yi-Hong Zhou

Cancer Res (2005) 65 (9_Supplement): 1149.

Published: 01 May 2005

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Journal Articles

Cytoplasmic translocation of PTEN tumor suppressor is mediated by PI3K/Akt/mTOR/p70S6K signaling cascades

Juinn-Lin Liu, Kenneth D. Aldape, Zhenyu Mao, W. K. Alfred Yung

Cancer Res (2005) 65 (9_Supplement): 236.

Published: 01 May 2005

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Journal Articles

Down-regulation of neuropilin-1 expression by RAD001 attenuates glioma cells invasion.

Ta-Jen Liu, Tiffany Lafortune, John De Groot, W. K. Alfred Yung

Cancer Res (2005) 65 (9_Supplement): 64.

Published: 01 May 2005

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Journal Articles

Oncolytic adenovirus Icovir-2 shows improved therapeutic index than D24-RGD for glioma

Marta M. Alonso, Ramon Alemany, Candelaria Gomez-Manzano, W. K. Alfred Yung, Hong Jiang, Juan Fueyo

Cancer Res (2005) 65 (9_Supplement): 312–313.

Published: 01 May 2005

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Journal Articles

Polymorphisms of DNA Repair Genes and Risk of Glioma

Li-E Wang, Melissa L. Bondy, Hongbing Shen, Randa El-Zein, Kenneth Aldape, Yumei Cao, Vinay Pudavalli, Victor A. Levin, W. K. Alfred Yung, Qingyi Wei

Cancer Res (2004) 64 (16): 5560–5563.

DOI: https://doi.org/10.1158/0008-5472.CAN-03-2181

Published: 16 August 2004

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Significant correlation of Angiopoietin-2 and Nestin expression in glioblastomas.

Candelaria Gomez-Manzano, Jing Xu, Juan Fueyo, Kenneth D. Aldape, B. Nebiyou Bekele, Michael G. Lemoine, Gregory N. Fuller, W. K. Alfred Yung

Cancer Res (2004) 64 (7_Supplement): 830.

Published: 01 April 2004

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Journal Articles

Prognostic model for glioma patients

Yi-Hong Zhou, Kenneth R. Hess, W. K. Alfred Yung

Cancer Res (2004) 64 (7_Supplement): 245.

Published: 01 April 2004

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Journal Articles

The farnesyltransferase inhibitor Zarnestra suppresses protein farnesylation, not geranylgeranylation, in peripheral blood monocytes of patients with recurrent malignant glioma treated with Zarnestra in phase I/II clinical trials

Cancer Res (2004) 64 (7_Supplement): 920.

Published: 01 April 2004

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Journal Articles

VEGF₁₂₁, VEGF₁₆₅ Overexpression Enhances Tumorigenicity in U251 MG but not in NG-1 Glioma Cells

Li Dao Ke, Yue-Xi Shi, W. K. Alfred Yung

Cancer Res (2002) 62 (6): 1854–1861.

Published: 15 March 2002

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Journal Articles

Transfer of E2F-1 to Human Glioma Cells Results in Transcriptional Up-Regulation of Bcl-2

Candelaria Gomez-Manzano, Paraskevi Mitlianga, Juan Fueyo, Ho-Young Lee, Min Hu, Kevin B. Spurgers, Tricia L. Glass, Dimpy Koul, Ta-Jen Liu, Timothy J. McDonnell, W. K. Alfred Yung

Cancer Res (2001) 61 (18): 6693–6697.

Published: 01 September 2001

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Reactivation of Insulin-like Growth Factor Binding Protein 2 Expression in Glioblastoma Multiforme: A Revelation by Parallel Gene Expression Profiling

Gregory N. Fuller, Chang Hun Rhee, Kenneth R. Hess, Laura S. Caskey, Ruoping Wang, Janet M. Bruner, W. K. Alfred Yung, Wei Zhang

Cancer Res (1999) 59 (17): 4228–4232.

Published: 01 September 1999

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Journal Articles

Regulation of Akt/PKB Activity, Cellular Growth, and Apoptosis in Prostate Carcinoma Cells by MMAC/PTEN

Michael A. Davies, Dimpy Koul, Haninder Dhesi, Russell Berman, Timothy J. McDonnell, David McConkey, W. K. Alfred Yung, Peter A. Steck

Cancer Res (1999) 59 (11): 2551–2556.

Published: 01 June 1999

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Journal Articles

Differential Expression of MMAC/PTEN in Glioblastoma Multiforme: Relationship to Localization and Prognosis

Tetsuro Sano, Huai Lin, Xiashan Chen, Lauren A. Langford, Dimpy Koul, Melissa L. Bondy, Kenneth R. Hess, Jeffrey N. Myers, Yong-Kil Hong, W. K. Alfred Yung, Peter A. Steck

Cancer Res (1999) 59 (8): 1820–1824.

Published: 01 April 1999

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Journal Articles

Antiangiogenesis Treatment for Gliomas: Transfer of Antisense-Vascular Endothelial Growth Factor Inhibits Tumor Growth in Vivo

Seock-Ah Im, Candelaria Gomez-Manzano, Juan Fueyo, Ta-Jen Liu, Li Dao Ke, Jeong-Soo Kim, Ho-Young Lee, Peter A. Steck, Athanassios P. Kyritsis, W. K. Alfred Yung

Cancer Res (1999) 59 (4): 895–900.

Published: 01 February 1999

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Journal Articles

Adenoviral Transgene Expression of MMAC/PTEN in Human Glioma Cells Inhibits Akt Activation and Induces Anoikis

Michael A. Davies, Yiling Lu, Tetsuro Sano, Xianjun Fang, Ping Tang, Ruth LaPushin, Dimpy Koul, Robert Bookstein, David Stokoe, W. K. Alfred Yung, Gordon B. Mills, Peter A. Steck

Cancer Res (1998) 58 (23): 5285–5290.

Published: 01 December 1998

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Journal Articles

MMAC1/PTEN Mutations in Primary Tumor Specimens and Tumor Cell Lines

Cancer Res (1997) 57 (23): 5221–5225.

Published: 01 December 1997

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NARROW

Abstract 350: NVP-BKM120: A selective pan-PI3 kinase inhibitor induces G2/M arrest in glioma cell lines via FOXO3a and GADD45a loop

Abstract #4800: WP1193 Inhibits JAK2/STAT3 Pathway, blocks self-renewal and induces apoptosis in glioblastoma cancer stem cells

E2F1 transcriptionally activates PTEN

Treatment of glioma-bearing mice with VEGF Trap results in significant prolongation of survival

The expression of VEGF, CDK4, PAX6, EGFR, IGFBP2, PTEN, MMP2 and P53 in patients with oligodendrogliomas: Relationship to 5-year mortality

Cytoplasmic translocation of PTEN tumor suppressor is mediated by PI3K/Akt/mTOR/p70S6K signaling cascades

Down-regulation of neuropilin-1 expression by RAD001 attenuates glioma cells invasion.

Oncolytic adenovirus Icovir-2 shows improved therapeutic index than D24-RGD for glioma

Polymorphisms of DNA Repair Genes and Risk of Glioma

Significant correlation of Angiopoietin-2 and Nestin expression in glioblastomas.

Prognostic model for glioma patients

The farnesyltransferase inhibitor Zarnestra suppresses protein farnesylation, not geranylgeranylation, in peripheral blood monocytes of patients with recurrent malignant glioma treated with Zarnestra in phase I/II clinical trials

VEGF₁₂₁, VEGF₁₆₅ Overexpression Enhances Tumorigenicity in U251 MG but not in NG-1 Glioma Cells

Transfer of E2F-1 to Human Glioma Cells Results in Transcriptional Up-Regulation of Bcl-2

Reactivation of Insulin-like Growth Factor Binding Protein 2 Expression in Glioblastoma Multiforme: A Revelation by Parallel Gene Expression Profiling

Regulation of Akt/PKB Activity, Cellular Growth, and Apoptosis in Prostate Carcinoma Cells by MMAC/PTEN

Differential Expression of MMAC/PTEN in Glioblastoma Multiforme: Relationship to Localization and Prognosis

Antiangiogenesis Treatment for Gliomas: Transfer of Antisense-Vascular Endothelial Growth Factor Inhibits Tumor Growth in Vivo

Adenoviral Transgene Expression of MMAC/PTEN in Human Glioma Cells Inhibits Akt Activation and Induces Anoikis

MMAC1/PTEN Mutations in Primary Tumor Specimens and Tumor Cell Lines

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