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Vivek M. Rangnekar
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Journal Articles

Abstract 1103: Molecular signature for treatment-responsive and recurrent Wilms tumors

Jieyun Jiang, Derek B. Allison, Ravshan Burikhanov, Saptadwipa Ganguly, Ryan A. Goettl, Jinpeng Liu, Chi Wang, Amanda F. Saltzman, Thomas Tucker, Peter H. Spielmann, Eric B. Durbin, John A. D’Orazio, Vivek M. Rangnekar
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1103.
https://doi.org/10.1158/1538-7445.AM2024-1103
Published: 22 March 2024
View article titled, Abstract 1103: Molecular signature for treatment-responsive and recurrent Wilms tumors
Journal Articles

A Naturally Generated Decoy of the Prostate Apoptosis Response-4 Protein Overcomes Therapy Resistance in Tumors

Nikhil Hebbar, Ravshan Burikhanov, Nidhi Shukla, Shirley Qiu, Yanming Zhao, Kojo S.J. Elenitoba-Johnson, Vivek M. Rangnekar
Journal: Cancer Research
Cancer Res (2017) 77 (15): 4039–4050.
https://doi.org/10.1158/0008-5472.CAN-16-1970
Published: 01 August 2017
View article titled, A Naturally Generated Decoy of the Prostate Apoptosis Response-4 Protein Overcomes Therapy Resistance in Tumors
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Includes: Supplementary data
Journal Articles

Abstract A52: Paracrine apoptotic effect of the tumor suppressor p53 is mediated by secreted Par-4

Tripti Shrestha-Bhattarai, Ravshan Burikhanov, Nikhil Hebbar, Shirley Qiu, Yanming Zhao, Gerard P. Zambetti, Vivek M. Rangnekar
Journal: Cancer Research
Cancer Res (2015) 75 (1_Supplement): A52.
https://doi.org/10.1158/1538-7445.CHTME14-A52
Published: 12 January 2015
View article titled, Abstract A52: Paracrine apoptotic effect of the tumor suppressor p53 is mediated by secreted Par-4
Journal Articles

Novel Mechanism of Apoptosis Resistance in Cancer Mediated by Extracellular PAR-4

Ravshan Burikhanov, Tripti Shrestha-Bhattarai, Shirley Qiu, Nidhi Shukla, Nikhil Hebbar, Subodh M. Lele, Craig Horbinski, Vivek M. Rangnekar
Journal: Cancer Research
Cancer Res (2013) 73 (2): 1011–1019.
https://doi.org/10.1158/0008-5472.CAN-12-3212
Published: 16 January 2013
View article titled, Novel Mechanism of Apoptosis Resistance in Cancer Mediated by Extracellular PAR-4
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Includes: Supplementary data
Journal Articles

Abstract LB-133: Golgin-160 binds to the tumor suppressor Par-4 and attenuates its secretion

Tripti Shrestha Bhattarai, Jaya Singh, Guofang Qiu, Carolyn E. Machamer, Vivek M. Rangnekar
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-133.
https://doi.org/10.1158/1538-7445.AM2011-LB-133
Published: 15 April 2011
View article titled, Abstract LB-133: Golgin-160 binds to the tumor suppressor Par-4 and attenuates its secretion
Journal Articles

RIP1 Activates PI3K-Akt via a Dual Mechanism Involving NF-κB–Mediated Inhibition of the mTOR-S6K-IRS1 Negative Feedback Loop and Down-regulation of PTEN

Seongmi Park, Dawen Zhao, Kimmo J. Hatanpaa, Bruce E. Mickey, Debabrata Saha, David A. Boothman, Michael D. Story, Eric T. Wong, Sandeep Burma, Maria-Magdalena Georgescu, Vivek M. Rangnekar, Sandili S. Chauncey, Amyn A. Habib
Journal: Cancer Research
Cancer Res (2009) 69 (10): 4107–4111.
https://doi.org/10.1158/0008-5472.CAN-09-0474
Published: 15 May 2009
View article titled, RIP1 Activates PI3K-Akt via a Dual Mechanism Involving NF-κB–Mediated Inhibition of the mTOR-S6K-IRS1 Negative Feedback Loop and Down-regulation of PTEN
Open the PDF for RIP1 Activates PI3K-Akt via a Dual Mechanism Involving NF-κB–Mediated Inhibition of the mTOR-S6K-IRS1 Negative Feedback Loop and Down-regulation of PTEN in another window
Includes: Supplementary data
Journal Articles

Par-4 Binds to Topoisomerase 1 and Attenuates Its DNA Relaxation Activity

Anindya Goswami, Shirley Qiu, Thomas S. Dexheimer, Padhma Ranganathan, Ravshan Burikhanov, Yves Pommier, Vivek M. Rangnekar
Journal: Cancer Research
Cancer Res (2008) 68 (15): 6190–6198.
https://doi.org/10.1158/0008-5472.CAN-08-0831
Published: 01 August 2008
View article titled, Par-4 Binds to Topoisomerase 1 and Attenuates Its DNA Relaxation Activity
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Includes: Supplementary data
Journal Articles

Role of Tumor Necrosis Factor-α and TRAIL in High-Dose Radiation–Induced Bystander Signaling in Lung Adenocarcinoma

Mohammed M. Shareef, Nuan Cui, Ravshan Burikhanov, Seema Gupta, Sabapathi Satishkumar, Shahin Shajahan, Mohammed Mohiuddin, Vivek M. Rangnekar, Mansoor M. Ahmed
Journal: Cancer Research
Cancer Res (2007) 67 (24): 11811–11820.
https://doi.org/10.1158/0008-5472.CAN-07-0722
Published: 18 December 2007
View article titled, Role of Tumor Necrosis Factor-α and TRAIL in High-Dose Radiation–Induced Bystander Signaling in Lung Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Suppression of PTEN Expression Is Essential for Antiapoptosis and Cellular Transformation by Oncogenic Ras

Krishna Murthi Vasudevan, Ravshan Burikhanov, Anindya Goswami, Vivek M. Rangnekar
Journal: Cancer Research
Cancer Res (2007) 67 (21): 10343–10350.
https://doi.org/10.1158/0008-5472.CAN-07-1827
Published: 01 November 2007
View article titled, Suppression of PTEN Expression Is Essential for Antiapoptosis and Cellular Transformation by Oncogenic Ras
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Journal Articles

Cancer Resistance in Transgenic Mice Expressing the SAC Module of Par-4

Yanming Zhao, Ravshan Burikhanov, Shirley Qiu, Subodh M. Lele, C. Darrell Jennings, Subbarao Bondada, Brett Spear, Vivek M. Rangnekar
Journal: Cancer Research
Cancer Res (2007) 67 (19): 9276–9285.
https://doi.org/10.1158/0008-5472.CAN-07-2124
Published: 01 October 2007
View article titled, Cancer Resistance in Transgenic Mice Expressing the SAC Module of Par-4
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Includes: Supplementary data
Journal Articles

The Phosphoinositide 3-Kinase/Akt1/Par-4 Axis: A Cancer-Selective Therapeutic Target

Anindya Goswami, Padhma Ranganathan, Vivek M. Rangnekar
Journal: Cancer Research
Cancer Res (2006) 66 (6): 2889–2892.
https://doi.org/10.1158/0008-5472.CAN-05-4458
Published: 15 March 2006
View article titled, The Phosphoinositide 3-Kinase/Akt1/Par-4 Axis: A Cancer-Selective Therapeutic Target
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Journal Articles

Androgen receptor dependent regulation of apoptosis by a herbal compound in prostate cancer

Damodaran Chendil, Srinivasan Sowmyalakshmi, Rama Ranga, Ravshan Burikhanov, Vivek M. Rangnekar
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1221–1222.
Published: 01 May 2005
View article titled, Androgen receptor dependent regulation of apoptosis by a herbal compound in prostate cancer
Journal Articles

Vitamin E induces apoptosis of cancer cells by nuclear translocation of Par-4

Yanming Zhao, Priyanka Srinivasan, Vivek M. Rangnekar
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1005.
Published: 01 April 2004
View article titled, Vitamin E induces apoptosis of cancer cells by nuclear translocation of Par-4
Journal Articles

In Lymphatic Cells Par-4 Sensitizes to Apoptosis by Down-Regulating Bcl-2 and Promoting Disruption of Mitochondrial Membrane Potential and Caspase Activation

Simone Boehrer, Kai U. Chow, Florian Beske, Natasa Kukoc-Zivojnov, Elena Puccetti, Martin Ruthardt, Christine Baum, Vivek M. Rangnekar, Dieter Hoelzer, Paris S. Mitrou, Eckhart Weidmann
Journal: Cancer Research
Cancer Res (2002) 62 (6): 1768–1775.
Published: 15 March 2002
View article titled, In Lymphatic Cells Par-4 Sensitizes to Apoptosis by Down-Regulating Bcl-2 and Promoting Disruption of Mitochondrial Membrane Potential and Caspase Activation
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Journal Articles

Par-4 Drives Trafficking and Activation of Fas and FasL to Induce Prostate Cancer Cell Apoptosis and Tumor Regression

Mala Chakraborty, Shirley Guofang Qiu, Krishna Murthi Vasudevan, Vivek M. Rangnekar
Journal: Cancer Research
Cancer Res (2001) 61 (19): 7255–7263.
Published: 01 October 2001
View article titled, Par-4 Drives Trafficking and Activation of Fas and FasL to Induce Prostate Cancer Cell Apoptosis and Tumor Regression
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