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Journal Articles

Abstract 5864: YAP1 defines a highly plastic, persister cell population in small cell lung cancer (SCLC) following relapse

C. Allison Stewart, Sarah M. Groves, Runsheng Wang, Kavya Ramkumar, Yuanxin Xi, Lixia Diao, Alejandra G. Serrano, Azusa Tanimoto, Ashley M. Victorian, Sayantan Bhattacharyya, Alexa J. Halliday, Neda Kalhor, Luisa Maren Soto, Pedro Filipe Da Rocha, Natalie Vokes, Loukia G. Karacosta, Jing Wang, John V. Heymach, Vito Quaranta, Bonnie Glisson, Lauren Averett Byers, Carl M. Gay
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5864.
https://doi.org/10.1158/1538-7445.AM2024-5864
Published: 22 March 2024
View articletitled, Abstract 5864: YAP1 defines a highly plastic, persister cell population in small cell lung cancer (SCLC) following relapse
Journal Articles

Abstract 5308: Analysis of extracellular vesicle surface markers as small cell lung cancer biomarkers

Patricia M. Ozawa, Sarah M. Groves, Vito Quaranta, Alissa M. Weaver
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5308.
https://doi.org/10.1158/1538-7445.AM2023-5308
Published: 04 April 2023
View articletitled, Abstract 5308: Analysis of extracellular vesicle surface markers as small cell lung cancer biomarkers
Journal Articles

Abstract P1-08-20: In silico analysis of a novel mathematical model integrating in vitro and in vivo imaging data reveals driving mechanisms of breast cancer response to NAT for personalized tumor forecasting

Guillermo Lorenzo, Angela M. Jarrett, Christian T. Meyer, Darren R. Tyson, Vito Quaranta, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-08-20.
https://doi.org/10.1158/1538-7445.SABCS21-P1-08-20
Published: 15 February 2022
View articletitled, Abstract P1-08-20: In silico analysis of a novel mathematical model integrating in vitro and in vivo imaging data reveals driving mechanisms of breast cancer response to NAT for personalized tumor forecasting
Journal Articles

Ralph A. Reisfeld, PhD: In Memoriam (1926–2020)

James P. Allison, Edward Barker, Jürgen C. Becker, Thomas F. Bumol, David Cheresh, Bill Church, Soldano Ferrone, Darrell R. Galloway, Martin Giedlin, Stephen Gillies, Rupert Handgretinger, John R. Harper, Kohzoh Imai, Barry Kahan, Ruth Ladenstein, Debbie Liao, Holger N. Lode, Hans Loibner, Yun-Ping Luo, Barbara M. Mueller, AhKau Ng, Andreas Niethammer, Michele Pellegrino, Ursula Pertl, Vito Quaranta, Carlo Russo, Helen Sabzevari, Martin Schrappe, Gregor Schulz, Paul Sondel, Andreas Stahl, Argyrios Theophilopoulos, Nissi Varki, Leslie Walker, Barry Wilson, Wolfgang Wrasidlo, Ursula Wargalla-Plate, Rong Xiang, Alice Yu, He Zhou
Journal: Cancer Research
Cancer Res (2021) 81 (6): 1429–1430.
https://doi.org/10.1158/0008-5472.CAN-21-0450
Published: 15 March 2021
View articletitled, Ralph A. Reisfeld, PhD: In Memoriam (1926–2020)
Open the PDF for Ralph A. Reisfeld, PhD: In Memoriam (1926–2020) in another window
Journal Articles

Abstract PS13-44: Identifying relevant parameters that characterize the early response to NAT in breast cancer patients using a novel personalized mechanistic model integrating in vitro and in vivo imaging data

Guillermo Lorenzo, Angela M. Jarrett, Christian T. Meyer, Darren R. Tyson, Vito Quaranta, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS13-44.
https://doi.org/10.1158/1538-7445.SABCS20-PS13-44
Published: 15 February 2021
View articletitled, Abstract PS13-44: Identifying relevant parameters that characterize the early response to NAT in breast cancer patients using a novel personalized mechanistic model integrating in vitro and in vivo imaging data
Journal Articles

An Integrative Gene Expression and Mathematical Flux Balance Analysis Identifies Targetable Redox Vulnerabilities in Melanoma Cells

B. Bishal Paudel, Joshua E. Lewis, Keisha N. Hardeman, Corey E. Hayford, Charles J. Robbins, Philip E. Stauffer, Simona G. Codreanu, Stacy D. Sherrod, John A. McLean, Melissa L. Kemp, Vito Quaranta
Journal: Cancer Research
Cancer Res (2020) 80 (20): 4565–4577.
https://doi.org/10.1158/0008-5472.CAN-19-3588
Published: 15 October 2020
View articletitled, An Integrative Gene Expression and Mathematical Flux Balance Analysis Identifies Targetable Redox Vulnerabilities in Melanoma Cells
Open the PDF for An Integrative Gene Expression and Mathematical Flux Balance Analysis Identifies Targetable Redox Vulnerabilities in Melanoma Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 670: Molecular basis of the idling state uncovers vulnerabilities suitable to sequential targeting in melanoma

Corey E. Hayford, Bishal B. Paudel, Leonard A. Harris, Keisha N. Hardeman, Darren R. Tyson, Vito Quaranta
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 670.
https://doi.org/10.1158/1538-7445.AM2019-670
Published: 01 July 2019
View articletitled, Abstract 670: Molecular basis of the idling state uncovers vulnerabilities suitable to sequential targeting in melanoma
Journal Articles

Abstract 2894: Overcoming intrinsic resistance to BRAF-inhibitors by modulating redox balance inBRAF-mutated melanoma cells

B. Bishal Paudel, Leonard A. Harris, Keisha N. Hardeman, Corey E. Hayford, Christian T. Meyer, Arwa A. Abugable, Darren R. Tyson, Joshua P. Fessel, Vito Quaranta
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2894.
https://doi.org/10.1158/1538-7445.AM2019-2894
Published: 01 July 2019
View articletitled, Abstract 2894: Overcoming intrinsic resistance to BRAF-inhibitors by modulating redox balance inBRAF-mutated melanoma cells
Journal Articles

Correction: Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity

Akshata R. Udyavar, David J. Wooten, Megan Hoeksema, Mukesh Bansal, Andrea Califano, Lourdes Estrada, Santiago Schnell, Jonathan M. Irish, Pierre P. Massion, Vito Quaranta
Journal: Cancer Research
Cancer Res (2019) 79 (5): 1014.
https://doi.org/10.1158/0008-5472.CAN-19-0069
Published: 01 March 2019
View articletitled, Correction: Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity
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Journal Articles

Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity

Akshata R. Udyavar, David J. Wooten, Megan Hoeksema, Mukesh Bansal, Andrea Califano, Lourdes Estrada, Santiago Schnell, Jonathan M. Irish, Pierre P. Massion, Vito Quaranta
Journal: Cancer Research
Cancer Res (2017) 77 (5): 1063–1074.
https://doi.org/10.1158/0008-5472.CAN-16-1467
Published: 28 February 2017
View articletitled, Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity
Open the PDF for Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity in another window
Includes: Supplementary data
Journal Articles

Abstract A09: Predicting response to whole brain radiotherapy in a murine model of glioma

David A. Hormuth, II, Jared A. Weis, Stephanie B. Eldridge, Michael I. Miga, Erin C. Rericha, Vito Quaranta, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2017) 77 (2_Supplement): A09.
https://doi.org/10.1158/1538-7445.EPSO16-A09
Published: 16 January 2017
View articletitled, Abstract A09: Predicting response to whole brain radiotherapy in a murine model of glioma
Journal Articles

Abstract A14: Predicting the response of triple negative breast cancer to doxorubicin

Matthew T. McKenna, Stephanie L. Barnes, Jared A. Weis, Abigail M. Searfoss, Darren R. Tyson, Erin C. Rericha, Michael I. Miga, Vito Quaranta, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2017) 77 (2_Supplement): A14.
https://doi.org/10.1158/1538-7445.EPSO16-A14
Published: 16 January 2017
View articletitled, Abstract A14: Predicting the response of triple negative breast cancer to doxorubicin
Journal Articles

Abstract A22: A window into 3D culture: A multi-modal imaging compatible bioreactor for developing tumor growth models

Abigail M. Searfoss, Matthew T. McKenna, Vito Quaranta, Thomas E. Yankeelov, Erin C. Rericha
Journal: Cancer Research
Cancer Res (2017) 77 (2_Supplement): A22.
https://doi.org/10.1158/1538-7445.EPSO16-A22
Published: 16 January 2017
View articletitled, Abstract A22: A window into 3D culture: A multi-modal imaging compatible bioreactor for developing tumor growth models
Journal Articles

Abstract 776: Multiscale treatment response model for triple-negative breast cancer linking drug pharmacokinetics to tumor cell population dynamics

Matthew T. McKenna, Stephanie L. Barnes, Abigail Searfoss, Darren R. Tyson, Erin Rericha, Vito Quaranta, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 776.
https://doi.org/10.1158/1538-7445.AM2016-776
Published: 15 July 2016
View articletitled, Abstract 776: Multiscale treatment response model for triple-negative breast cancer linking drug pharmacokinetics to tumor cell population dynamics
Journal Articles

Abstract 3761: Distinct transcriptional programs drive phenotypic heterogeneity in small cell lung cancer

Akshata R. Udyavar, Megan Hoeksema, David J. Wooten, Mukesh Bansal, Andrea Califano, Lourdes Estrada, Jonathan Irish, Pierre Massion, Vito Quaranta
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3761.
https://doi.org/10.1158/1538-7445.AM2015-3761
Published: 01 August 2015
View articletitled, Abstract 3761: Distinct transcriptional programs drive phenotypic heterogeneity in small cell lung cancer
Journal Articles

Abstract 3747: Identification of NSCLC biomarkers underlying quantifiable drug-induced clonal fitness

Katherine L. Jameson, Peter L. Frick, Darren R. Tyson, Thomas E. Yankeelov, Vito Quaranta
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3747.
https://doi.org/10.1158/1538-7445.AM2015-3747
Published: 01 August 2015
View articletitled, Abstract 3747: Identification of NSCLC biomarkers underlying quantifiable drug-induced clonal fitness
Journal Articles

Toward a Science of Tumor Forecasting for Clinical Oncology

Thomas E. Yankeelov, Vito Quaranta, Katherine J. Evans, Erin C. Rericha
Journal: Cancer Research
Cancer Res (2015) 75 (6): 918–923.
https://doi.org/10.1158/0008-5472.CAN-14-2233
Published: 12 March 2015
View articletitled, Toward a Science of Tumor Forecasting for Clinical Oncology
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Journal Articles

Abstract 1845: Sensitivity of PC9 cells to erlotinib is affected by extracellular matrix

Halina M. Onishko, Jie Zhao, Katherine L. Jameson, Peter L. Frick, Darren R. Tyson, Vito Quaranta, Thomas E. Yankeelov, Erin C. Rericha
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1845.
https://doi.org/10.1158/1538-7445.AM2014-1845
Published: 01 October 2014
View articletitled, Abstract 1845: Sensitivity of PC9 cells to erlotinib is affected by extracellular matrix
Journal Articles

Abstract 4626: Quantifying erlotinib response variability in EGFR-addicted cells.

Peter L. Frick, Darren R. Tyson, Shawn P. Garbett, Carlos F. Lopez, Zach W. Jones, Vito Quaranta
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4626.
https://doi.org/10.1158/1538-7445.AM2013-4626
Published: 15 April 2013
View articletitled, Abstract 4626: Quantifying erlotinib response variability in EGFR-addicted cells.
Journal Articles

Abstract 3403: A stochastically arising subpopulation of B-RafV600E-expressing melanoma continues division in the presence of vemurafenib.

Darren R. Tyson, Chengwei Peng, Keisha N. Hardeman, Bishal Paudel, Vito Quaranta
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3403.
https://doi.org/10.1158/1538-7445.AM2013-3403
Published: 15 April 2013
View articletitled, Abstract 3403: A stochastically arising subpopulation of B-RafV600E-expressing melanoma continues division in the presence of vemurafenib.