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Vincent A. Miller
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Journal Articles

Abstract GS6-04: Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, breast cancer progression, and HER2 inhibitor sensitivity

Ariella B. Hanker, Harikrishna Sekar Jayanthan, Dan Ye, Chang-Ching Lin, Hiroaki Akamatsu, Jonathan H. Sheehan, James P. Koch, Dhivya R. Sudhan, Monica Red Brewer, Alberto Servetto, Jie He, Vincent A. Miller, Alshad S. Lalani, Jens Meiler, Carlos L. Arteaga
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): GS6-04.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-GS6-04
Published: 15 February 2020
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Journal Articles

Abstract P4-06-07: PIK3CA-mutant breast phyllodes tumors show a uniformly aggressive histology and significant mutual exclusivity with MED12 mutation

Erik A Williams, Ethan S Sokol, Dean C Pavlick, Nikunj Shah, Julia A Elvin, Jo-Anne Vergilio, Jonathan K Killian, Nhu Ngo, Douglas Lin, Vincent A Miller, Jeffrey S Ross
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P4-06-07.
DOI: https://doi.org/10.1158/1538-7445.SABCS19-P4-06-07
Published: 15 February 2020
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Journal Articles

Abstract 3105: Serial profiling of ctDNA identifies clinically actionable genomic evolution in high-risk neuroblastoma

Kristopher R. Bosse, Samantha Buongervino, Maria Lane, Adam Hyman, Maria Gemino-borromeo, Jennifer Saggio, Alana Fitzsimmons, Brady Forcier, Anne Murphy, John Wick, Matthew Cooke, Jennifer Webster, Russell Madison, Alley Welsh, Vincent A. Miller, Siraj M. Ali, John M. Maris, Yael P. Mosse
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3105.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3105
Published: 01 July 2019
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Journal Articles

Abstract 930: On-target resistance to mutant selective EGFR inhibitors develops in an allele-specific manner dependent on the original EGFR activating mutation

Yunkai Zhang, Benjamin P. Brown, David Westover, Yingjun Yan, Huan Qiao, Vincent Huang, Zhenfang Du, Jarrod A. Smith, Jeffrey S. Ross, Vincent A. Miller, Siraj Ali, Lyudmila Bazhenova, Alexa B. Schrock, Jens Meiler, Christine M. Lovly
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 930.
DOI: https://doi.org/10.1158/1538-7445.AM2019-930
Published: 01 July 2019
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Journal Articles

Abstract 1833: Identification of resistance mechanisms to EGFR treatment in the real world using a clinicogenomic database

Gaurav Singal, Gerald Li, Vineeta Agarwala, Gaurav Kaushik, Claire O'Connell, Garrett A. Cobb, Thomas Caron, David Bourque, Ameet Guria, Shannon Frank, Garrett Frampton, Ken Carson, Amy Abernethy, Vincent A. Miller
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1833.
DOI: https://doi.org/10.1158/1538-7445.AM2018-1833
Published: 01 July 2018
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Journal Articles

Abstract 417: Comparative analysis of clinically validated NGS-based assays reveals high concordance across short variants

Ninad P. Dewal, Joel Skoletsky, Wai-Ki Yip, Caitlin Patriquin, Yuting He, Jeffrey S. Ross, Vincent A. Miller, Philip J. Stephens, Christine Burns, Christine Vietz, Yali Li, Colin Pritchard, James X. Sun
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 417.
DOI: https://doi.org/10.1158/1538-7445.AM2018-417
Published: 01 July 2018
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Journal Articles

Abstract 3394: CGP identifies largely non-overlapping high tumor mutational burden and HRD genomic alterations in 721 clinically advanced prostate acinar adenocarcinoma cases

Ninad Dewal, Yuting He, Richard J. Lee, Alexa B. Schrock, Jon Chung, Christopher Hoimes, Zachary R. Chalmers, Garrett M. Frampton, James X. Sun, Primo N. Lara, Neeraj Agrawal, Paul Matthew, Philip J. Stephens, Vincent A. Miller, Jeffrey S. Ross, Siraj M. Ali
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3394.
DOI: https://doi.org/10.1158/1538-7445.AM2017-3394
Published: 01 July 2017
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Journal Articles

Abstract 1775: The interaction of PD-L1, TMB, and genomic alterations in NSCLC

Michael E. Goldberg, Laurie M. Gay, David Fabrizio, Garrett M. Frampton, Julia A. Elvin, Jeffrey S. Ross, Vincent A. Miller, Philip J. Stephens, Lee A. Albacker
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1775.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1775
Published: 01 July 2017
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Journal Articles

Abstract 2987: Validation and clinical feasibility of a comprehensive genomic profiling assay to identify likely immunotherapy responders through tumor mutational burden (TMB)

Daniel S. Lieber, Mark R. Kennedy, Douglas B. Johnson, Jonathan E. Rosenberg, Marcin Kowanetz, Joel R. Greenbowe, Garrett M. Frampton, Caitlin F. Connelly, Alexa B. Schrock, Jeffrey S. Ross, Philip J. Stephens, Siraj M. Ali, Vincent A. Miller, David A. Fabrizio
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2987.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2987
Published: 01 July 2017
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Journal Articles

Genomic Profiling of a Large Set of Diverse Pediatric Cancers Identifies Known and Novel Mutations across Tumor Spectra

Juliann Chmielecki, Mark Bailey, Jie He, Julia Elvin, Jo-Anne Vergilio, Shakti Ramkissoon, James Suh, Garrett M. Frampton, James X. Sun, Samantha Morley, Daniel Spritz, Siraj Ali, Laurie Gay, Rachel L. Erlich, Jeffrey S. Ross, Joana Buxhaku, Hilary Davies, Vinny Faso, Alexis Germain, Blair Glanville, Vincent A. Miller, Philip J. Stephens, Katherine A. Janeway, John M. Maris, Soheil Meshinchi, Trevor J. Pugh, Jack F. Shern, Doron Lipson
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (2): 509–519.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-1106
Published: 16 January 2017
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Includes: Supplementary data
Journal Articles

Abstract 2431: Enrichment of targetable mutations in the relapsed neuroblastoma genome

Olivia M. Padovan-Merhar, Pichai Raman, Kaitlyn R. Rubnitz, Siraj M. Ali, Vincent A. Miller, Yael P. Mosse, Meaghan P. Granger, Brian D. Weiss, John M. Maris, Shakeel Modak
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2431.
DOI: https://doi.org/10.1158/1538-7445.AM2016-2431
Published: 15 July 2016
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Journal Articles

Abstract 3576: Broad analysis of recurrent somatic mutations in cancer reveals a common novel non-coding mutation in the promoter of PMS2 associated with greatly increased tumor mutation load

Zachary R. Chalmers, Franklin W. Huang, Laurie M. Gay, Siraj M. Ali, Roman Yelensky, Juliann Chmielecki, Jeffery S. Ross, Vincent A. Miller, Philip J. Stephens, Levi A. Garraway, Garrett M. Frampton
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3576.
DOI: https://doi.org/10.1158/1538-7445.AM2016-3576
Published: 15 July 2016
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Journal Articles

Abstract LB-178: Genomic profiling of 1239 diverse pediatric cancers identifies novel discoveries across tumors

Juliann Chmielecki, Mark Bailey, Jie He, Julia Elvin, Jo-Anne Vergilio, Shakti Ramkissoon, James Suh, Garrett M. Frampton, Siraj Ali, Jeffrey Ross, Vincent A. Miller, Philip J. Stephens, Doron Lipson
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-178.
DOI: https://doi.org/10.1158/1538-7445.AM2016-LB-178
Published: 15 July 2016
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Journal Articles

Abstract A46: Identification of NTRK fusions in pediatric tumors via comprehensive genomic profiling

Dean Pavlick, Siraj Mahamed Ali, Julia A. Elvin, Phil J. Stephens, Vincent A. Miller, Jeffrey S. Ross, James H. Suh, Jo-Anne Vergilio, Juliann Chmielecki, Tim Brennan, John R. Crawford, Denise M. Malicki, Hyunah Ahn, Victor N. Wong
Journal: Cancer Research
Cancer Res (2016) 76 (5_Supplement): A46.
DOI: https://doi.org/10.1158/1538-7445.PEDCA15-A46
Published: 04 April 2016
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Journal Articles

Abstract 1602: Development and validation of an NGS-based assay to detect all classes of genomic alterations in circulating tumor cells (CTCs) from patients with solid tumors

Allison Welsh, Garrett M. Frampton, Zachary R. Chalmers, Jamie Sperger, Roman Yelensky, Doron Lipson, Geoff Otto, Lindsay Strotman, Scott Berry, Hannah Pezzi, Anne Traynor, David J. Beebe, Vincent A. Miller, Joshua M. Lang, Philip J. Stephens
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1602.
DOI: https://doi.org/10.1158/1538-7445.AM2015-1602
Published: 01 August 2015
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Journal Articles

Abstract 497: Understanding oncogenic fusions: Lessons learned from inflammatory myofibroblastic tumor

Merrida A. Childress, Abha Gupta, Doron Lipson, Geoff Otto, Tina Brennan, Catherine T. Chung, Scott C. Borinstein, Jeffrey S. Ross, Phillip J. Stephens, Vincent A. Miller, Cheryl M. Coffin, Jason L. Hornick, Christine M. Lovly
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 497.
DOI: https://doi.org/10.1158/1538-7445.AM2015-497
Published: 01 August 2015
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Journal Articles

Abstract 4667: The complex genomic landscape of glial tumors reveals distinct subclasses and potential therapeutic targets associated with clinical responses to targeted inhibitors

Juliann Chmielecki, Michael E. Goldberg, Alex Fichtenholtz, Julia Elvin, Garrett M. Frampton, Siraj M. Ali, Jeffrey S. Ross, Deborah Morosini, Vincent A. Miller, David Piccioni, Santosh Kesari, Philip J. Stephens
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4667.
DOI: https://doi.org/10.1158/1538-7445.AM2015-4667
Published: 01 August 2015
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Journal Articles

Abstract 4670: A novel companion diagnostic predicts response to the PARP inhibitor rucaparib in ovarian cancer

James Sun, Iain McNeish, Robert L. Coleman, Amit Oza, Clare Scott, David M. O'Malley, Kevin K. Lin, Christine Burns, Christine Vietz, Philip J. Stephens, Murtaza Mehdi, Matthew Hawryluk, Heidi Giordano, Mitch Raponi, Lindsey Rolfe, Jeff Isaacson, Vincent A. Miller, Andrew Allen, Elizabeth Swisher, Roman Yelensky
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4670.
DOI: https://doi.org/10.1158/1538-7445.AM2015-4670
Published: 01 August 2015
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Journal Articles

Abstract 4737: Comprehensive profiling of immunoglobulin sequences using hybrid capture-based next generation sequencing in B-cell hematologic malignancies

Michelle K. Nahas, Lauren E. Young, Jeff Gardner, Omar Abdel-Wahab, Jie He, Amy L. Donahue, Kristina M. Knapp, Geoff A. Otto, Doron Lipson, Vincent A. Miller, Ross L. Levine, Philip J. Stephens
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4737.
DOI: https://doi.org/10.1158/1538-7445.AM2015-4737
Published: 01 August 2015
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Journal Articles

Abstract 4298: Defects in DNA repair genes and sensitivity to cisplatin based neoadjuvant chemotherapy (NAC) for bladder cancer

Elizabeth R. Plimack, Roland L. Dunbrack, Timothy A. Brennan, Mark D. Andrake, Yan Zhou, Ilya Serebriiskii, Essel Dulaimi Al-Saleem, Jean Hoffman-Censits, Marijo Bilusic, Yu-Ning Wong, Alexander Kutikov, Rosalia Viterbo, Richard Greenberg, David Chen, Costas D. Lallas, Edouard J. Trabulsi, Roman Yelensky, Vincent A. Miller, Erica Golemis, Eric Ross
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4298.
DOI: https://doi.org/10.1158/1538-7445.AM2015-4298
Published: 01 August 2015
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