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Viji Shridhar
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Journal Articles

Abstract 2391: Alterations in metformin mediated metabolism in chemoresistant ovarian cancer cells

Free
Brenita Colette Jenkins, Debarshi Roy, Kristal Maner-Smith, Viji Shridhar
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2391.
https://doi.org/10.1158/1538-7445.AM2022-2391
Published: 15 June 2022
View articletitled, Abstract 2391: Alterations in metformin mediated metabolism in chemoresistant ovarian cancer cells
Journal Articles

Exploiting LRRC15 as a Novel Therapeutic Target in Cancer

Open Access
Upasana Ray, Christopher L. Pathoulas, Prabhu Thirusangu, James W. Purcell, Nagarajan Kannan, Viji Shridhar
Journal: Cancer Research
Cancer Res (2022) 82 (9): 1675–1681.
https://doi.org/10.1158/0008-5472.CAN-21-3734
Published: 03 May 2022
View articletitled, Exploiting LRRC15 as a Novel Therapeutic Target in Cancer
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Journal Articles

Targeting LRRC15 Inhibits Metastatic Dissemination of Ovarian Cancer

Open Access
Upasana Ray, Deok-Beom Jung, Ling Jin, Yinan Xiao, Subramanyam Dasari, Sayantani Sarkar Bhattacharya, Prabhu Thirusangu, Julie K. Staub, Debarshi Roy, Bhaskar Roy, S. John Weroha, Xiaonan Hou, James W. Purcell, Jamie N. Bakkum-Gamez, Scott H. Kaufmann, Nagarajan Kannan, Anirban K. Mitra, Viji Shridhar
Journal: Cancer Research
Cancer Res (2022) 82 (6): 1038–1054.
https://doi.org/10.1158/0008-5472.CAN-21-0622
Published: 15 March 2022
View articletitled, Targeting LRRC15 Inhibits Metastatic Dissemination of Ovarian Cancer
Open the PDF for Targeting LRRC15 Inhibits Metastatic Dissemination of Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1936: Autophagy-dependent therapeutic targeting of group III phospholipase A2 attenuates ovarian cancer metastasis

Free
Upasana Ray, Debarshi Roy, Ling Jin, Prabhu Thirusangu, Julie Staub, Yinan Xiao, Viji Shridhar
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1936.
https://doi.org/10.1158/1538-7445.AM2021-1936
Published: 01 July 2021
View articletitled, Abstract 1936: Autophagy-dependent therapeutic targeting of group III phospholipase A2 attenuates ovarian cancer metastasis
Journal Articles

Abstract 1046: Synergistic cytotoxic effect of sulfated glycolipid PG545 in combination with ATR inhibition in ovarian cancer cells

Free
Yinan Xiao, Chaolin Deng, Ye Guan, Ling Jin, Upasana Ray, Prabhu Thirusangu, Julie Staub, Haotian Xu, Viji Shridhar
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1046.
https://doi.org/10.1158/1538-7445.AM2021-1046
Published: 01 July 2021
View articletitled, Abstract 1046: Synergistic cytotoxic effect of sulfated glycolipid PG545 in combination with ATR inhibition in ovarian cancer cells
Journal Articles

Abstract 6222: Inhibition of 6-Phosphofructo-2-kinase (PFKFB3) induces cell death and synergistically enhances chemosensitivity in endometrial cancer

Free
Yinan Xiao, Ling Jin, Sayantani Sarkar Bhattacharya, Julie Staub, Chaolin Deng, Xiaoling Fang, Viji Shridhar
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6222.
https://doi.org/10.1158/1538-7445.AM2020-6222
Published: 15 August 2020
View articletitled, Abstract 6222: Inhibition of 6-Phosphofructo-2-kinase (PFKFB3) induces cell death and synergistically enhances chemosensitivity in endometrial cancer
Journal Articles

Abstract 2658: PFKFB3 inhibition reprograms malignant pleural mesothelioma to glycolytic stress-induced macropinocytosis and ER stress as independent binary adaptive responses

Free
Sayantani Sarkar Bhattacharya, Ling Jin, Debarshi Roy, Deokbeom Jung, Prabhu Thirusangu, Yinan Xiao, Julie Staub, Julian Molina, Viji Shridhar
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2658.
https://doi.org/10.1158/1538-7445.AM2019-2658
Published: 01 July 2019
View articletitled, Abstract 2658: PFKFB3 inhibition reprograms malignant pleural mesothelioma to glycolytic stress-induced macropinocytosis and ER stress as independent binary adaptive responses
Journal Articles

Abstract 5821: Atorvastatin antagonizes carboplatin, synergizes with the glycolytic inhibitor PFK-158, and induces lipid laden multilamellar bodies in ovarian cancer

Free
Eleftheria Kalogera, Debarshi Roy, Jamie N. Bakkum-Gamez, William A. Cliby, Sean C. Dowdy, Viji Shridhar
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5821.
https://doi.org/10.1158/1538-7445.AM2018-5821
Published: 01 July 2018
View articletitled, Abstract 5821: Atorvastatin antagonizes carboplatin, synergizes with the glycolytic inhibitor PFK-158, and induces lipid laden multilamellar bodies in ovarian cancer
Journal Articles

Abstract 2203: A prospective study of endometrial cancer detection in women presenting for evaluation of abnormal peri- and postmenopausal bleeding

Free
Nicolas A. Wentzensen, Megan Clarke, Viji Shridhar, Maureen Lemens, Matthew Hopkins, Lisa Ahlberg, Shannon Laughlin-Tommaso, Karl Podratz, Mark Sherman, Jamie Bakkum-Gamez
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2203.
https://doi.org/10.1158/1538-7445.AM2018-2203
Published: 01 July 2018
View articletitled, Abstract 2203: A prospective study of endometrial cancer detection in women presenting for evaluation of abnormal peri- and postmenopausal bleeding
Journal Articles

Abstract 261: Quinacrine in endometrial cancer: repurposing an old antimalarial drug

Free
Eleftheria Kalogera, Debarshi Roy, Ashwani Khurana, Susmita Mondal, Xiaoping He, Sean C. Dowdy, Viji Shridhar
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 261.
https://doi.org/10.1158/1538-7445.AM2016-261
Published: 15 July 2016
View articletitled, Abstract 261: Quinacrine in endometrial cancer: repurposing an old antimalarial drug
Journal Articles

Abstract 1135: Loss of HSulf-1 promotes defective autophagy and increased lipid droplet biogenesis in ovarian cancer

Free
Debarshi Roy, Susmita Mondal, Ashwani Khurana, Xiaoping He, Edward Hammond, Keith Dredge, Viji Shridhar
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1135.
https://doi.org/10.1158/1538-7445.AM2015-1135
Published: 01 August 2015
View articletitled, Abstract 1135: Loss of HSulf-1 promotes defective autophagy and increased lipid droplet biogenesis in ovarian cancer
Journal Articles

Abstract 2706: Inhibition of PFKFB3/glycolysis overcomes chemoresistance in ovarian cancers

Free
Susmita Mondal, Debarshi Roy, Eleftheria Kalogera, Ashwani Khurana, Gilles H. Tapolsky, Sucheta Telang, Jason Chesney, Viji Shridhar
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2706.
https://doi.org/10.1158/1538-7445.AM2015-2706
Published: 01 August 2015
View articletitled, Abstract 2706: Inhibition of PFKFB3/glycolysis overcomes chemoresistance in ovarian cancers
Journal Articles

Abstract C38: Metformin inhibits cancer cell growth in an AMP kinase‐independent and ‐dependent manner

Free
Ramandeep Rattan, Shailendra Giri, Lynn C. Hartmann, Viji Shridhar
Journal: Cancer Research
Cancer Res (2009) 69 (23_Supplement): C38.
https://doi.org/10.1158/0008-5472.FBCR09-C38
Published: 28 October 2014
View articletitled, Abstract C38: Metformin inhibits cancer cell growth in an AMP kinase‐independent and ‐dependent manner
Journal Articles

Abstract 2439: HSulf-1 loss in ovarian cancer cells induces lipid droplet biogenesis

Free
Debarshi Roy, Xiaoping He, Ashwani Khurana, Susmita Mondal, Deok-Beom Jung, Sung Kim, Thomas Dierks, Clifford Folmes, Andre Terzic, Viji Shridhar
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2439.
https://doi.org/10.1158/1538-7445.AM2014-2439
Published: 01 October 2014
View articletitled, Abstract 2439: HSulf-1 loss in ovarian cancer cells induces lipid droplet biogenesis
Journal Articles

Abstract 3695: The utility of plasma vascular endothelial growth factor and heparanase as pharmacodynamic markers following treatment with PG545, a heparan sulfate mimetic: preliminary evidence from preclinical and clinical settings

Free
Keith Dredge, Edward Hammond, Boris Winterhoff, Shailendra Giri, Attila Teoman, Darryn Bampton, Michael Millward, Viji Shridhar
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3695.
https://doi.org/10.1158/1538-7445.AM2014-3695
Published: 01 October 2014
View articletitled, Abstract 3695: The utility of plasma vascular endothelial growth factor and heparanase as pharmacodynamic markers following treatment with PG545, a heparan sulfate mimetic: preliminary evidence from preclinical and clinical settings
Journal Articles

Tumor Hypomethylation at 6p21.3 Associates with Longer Time to Recurrence of High-Grade Serous Epithelial Ovarian Cancer

Free
Chen Wang, Mine S. Cicek, Bridget Charbonneau, Kimberly R. Kalli, Sebastian M. Armasu, Melissa C. Larson, Gottfried E. Konecny, Boris Winterhoff, Jian-Bing Fan, Marina Bibikova, Jeremy Chien, Viji Shridhar, Matthew S. Block, Lynn C. Hartmann, Daniel W. Visscher, Julie M. Cunningham, Keith L. Knutson, Brooke L. Fridley, Ellen L. Goode
Journal: Cancer Research
Cancer Res (2014) 74 (11): 3084–3091.
https://doi.org/10.1158/0008-5472.CAN-13-3198
Published: 29 May 2014
View articletitled, Tumor Hypomethylation at 6p21.3 Associates with Longer Time to Recurrence of High-Grade Serous Epithelial Ovarian Cancer
Open the PDF for Tumor Hypomethylation at 6p21.3 Associates with Longer Time to Recurrence of High-Grade Serous Epithelial Ovarian Cancer in another window
Journal Articles

APOBEC3B Upregulation and Genomic Mutation Patterns in Serous Ovarian Carcinoma

Free
Brandon Leonard, Steven N. Hart, Michael B. Burns, Michael A. Carpenter, Nuri A. Temiz, Anurag Rathore, Rachel I. Vogel, Jason B. Nikas, Emily K. Law, William L. Brown, Ying Li, Yuji Zhang, Matthew J. Maurer, Ann L. Oberg, Julie M. Cunningham, Viji Shridhar, Debra A. Bell, Craig April, David Bentley, Marina Bibikova, R. Keira Cheetham, Jian-Bing Fan, Russell Grocock, Sean Humphray, Zoya Kingsbury, John Peden, Jeremy Chien, Elizabeth M. Swisher, Lynn C. Hartmann, Kimberly R. Kalli, Ellen L. Goode, Hugues Sicotte, Scott H. Kaufmann, Reuben S. Harris
Journal: Cancer Research
Cancer Res (2013) 73 (24): 7222–7231.
https://doi.org/10.1158/0008-5472.CAN-13-1753
Published: 16 December 2013
View articletitled, APOBEC3B Upregulation and Genomic Mutation Patterns in Serous Ovarian Carcinoma
Open the PDF for APOBEC3B Upregulation and Genomic Mutation Patterns in Serous Ovarian Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 3477: Discovery and validation of methylation markers for early detection of endometrial cancer.

Free
Nicolas A. Wentzensen, Jamie Bakkum, Keith Killian, Viji Shridhar, Lisa Adams, Richard Guido, Lori D'Ambrosio, Patricia Luhn, Joshua Sampson, Hannah Yang, Louise Brinton, Jolanta Lissowska, Karl Podratz, Mark Sherman
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3477.
https://doi.org/10.1158/1538-7445.AM2013-3477
Published: 15 April 2013
View articletitled, Abstract 3477: Discovery and validation of methylation markers for early detection of endometrial cancer.
Journal Articles

Abstract 4960: The role of YY1 in paclitaxel-induced cytotoxicity in epithelial ovarian cancer

Free
Tsuyoshi Ota, Takayo Ota, Jeremy Chien, Viji Shridhar, Hirohisa Kurachi
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4960.
https://doi.org/10.1158/1538-7445.AM2012-4960
Published: 15 April 2012
View articletitled, Abstract 4960: The role of YY1 in paclitaxel-induced cytotoxicity in epithelial ovarian cancer
Journal Articles

Abstract 4179: Loss of Hsulf-1 promotes chemoresistance and tumorigenecity in ovarian cancer

Free
Xiaoping He, Ashwani Khurana, Scott Kaufmann, Viji Shridhar
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4179.
https://doi.org/10.1158/1538-7445.AM2012-4179
Published: 15 April 2012
View articletitled, Abstract 4179: Loss of Hsulf-1 promotes chemoresistance and tumorigenecity in ovarian cancer