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Abstract 1429: Forkhead box M1 (FoxM1) is a direct transcriptional target of EWS/FLI1 and a regulator of Ewing's sarcoma cell morphology, adhesiveness and tumorigenicity

Aniruddha Sengupta, Silvia Mateo-Lozano, Joaquin Villar, Caitlin M. MacCarthy, Oscar M. Tirado, Vicente Notario

Cancer Res (2012) 72 (8_Supplement): 1429.

DOI: https://doi.org/10.1158/1538-7445.AM2012-1429

Published: 15 April 2012

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Journal Articles

Abstract 3405: Caveolin-1 modulates the metastatic ability of Ewing's sarcoma

Miguel Sainz-Jaspeado, Laura Lagares-Tena, Jaime Lasheras, Fariba Navid, Carlos Rodriguez-Galindo, Silvia Mateo-Lozano, Vicente Notario, Xavier Sanjuan, Xavier Garcia del Muro, Angels Fabra, Oscar M. Tirado

Cancer Res (2010) 70 (8_Supplement): 3405.

DOI: https://doi.org/10.1158/1538-7445.AM10-3405

Published: 15 April 2010

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Journal Articles

Abstract #4930: GM2 synthase/GM3 synthase knockout transformed fibroblasts: a tumor model of complete ganglioside depletion

Yihui Liu, Yan Su, Michael Weiss, Margaret Sutherland, Joaquín Villar, Vicente Notario, Anamaris Colberg-Poley, Stephan Ladisch

Cancer Res (2009) 69 (9_Supplement): 4930.

Published: 01 May 2009

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Journal Articles

PCPH/ENTPD5 Expression Confers to Prostate Cancer Cells Resistance against Cisplatin-Induced Apoptosis through Protein Kinase Cα–Mediated Bcl-2 Stabilization

Joaquín Villar, Humair S. Quadri, Insun Song, York Tomita, Oscar M. Tirado, Vicente Notario

Cancer Res (2009) 69 (1): 102–110.

DOI: https://doi.org/10.1158/0008-5472.CAN-08-2922

Published: 31 December 2008

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Includes: Supplementary data

Journal Articles

PCPH/ENTPD5 Expression Enhances the Invasiveness of Human Prostate Cancer Cells by a Protein Kinase Cδ–Dependent Mechanism

Joaquín Villar, María Isabel Arenas, Caitlin M. MacCarthy, María José Blánquez, Oscar M. Tirado, Vicente Notario

Cancer Res (2007) 67 (22): 10859–10868.

DOI: https://doi.org/10.1158/0008-5472.CAN-07-2041

Published: 15 November 2007

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Journal Articles

Meriolins, a New Class of Cell Death–Inducing Kinase Inhibitors with Enhanced Selectivity for Cyclin-Dependent Kinases

Karima Bettayeb, Oscar M. Tirado, Séverine Marionneau-Lambot, Yoan Ferandin, Olivier Lozach, Jonathan C. Morris, Silvia Mateo-Lozano, Peter Drueckes, Christoph Schächtele, Michael H.G. Kubbutat, François Liger, Bernard Marquet, Benoît Joseph, Aude Echalier, Jane A. Endicott, Vicente Notario, Laurent Meijer

Cancer Res (2007) 67 (17): 8325–8334.

DOI: https://doi.org/10.1158/0008-5472.CAN-07-1826

Published: 05 September 2007

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Includes: Supplementary data

Journal Articles

Expression of the PCPH oncogene enhances the invasiness of prostate cancer cells by a PKCδ-dependent mechanism.

Joaquin Villar, Caittlin MacCarthy, Maria Isabel Arenas, Maria Jose Blanquez, Oscar Tirado, Vicente Notario

Cancer Res (2007) 67 (9_Supplement): 3926.

Published: 01 May 2007

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Journal Articles

Caveolin-1 (CAV1) Is a Target of EWS/FLI-1 and a Key Determinant of the Oncogenic Phenotype and Tumorigenicity of Ewing's Sarcoma Cells

Oscar M. Tirado, Silvia Mateo-Lozano, Joaquín Villar, Luis E. Dettin, Anna Llort, Soledad Gallego, Jozef Ban, Heinrich Kovar, Vicente Notario

Cancer Res (2006) 66 (20): 9937–9947.

DOI: https://doi.org/10.1158/0008-5472.CAN-06-0927

Published: 17 October 2006

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Includes: Supplementary data

Journal Articles

Caveolin-1 is a target of EWS/FLI-1 and a key determinant of tumorigenicity and resistance to chemotherapy-induced apoptosis of Ewing's sarcoma cells.

Oscar M. Tirado, Silvia Mateo-Lozano, Joaquin Villar, Luis E. Dettin, Anna Llort, Soledad Gallego, Vicente Notario

Cancer Res (2006) 66 (8_Supplement): 1324.

Published: 15 April 2006

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Journal Articles

Combination therapy targeting the EWS/FLI-1 oncogene with antisense oligonucleotides and rapamycin induces apoptosis of Ewing’s sarcoma cells in vitro and inhibits tumor growth in vivo

Silvia Mateo-Lozano, Prafulla C. Gokhale, Oscar M. Tirado, Vicente Notario

Cancer Res (2006) 66 (8_Supplement): 581.

Published: 15 April 2006

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Journal Articles

PCPH is differentially expressed in samples of benign and neoplastic human prostate, and contributes to maintaining the malignant phenotype of human prostate cancer cells

Joaquin Villar, Maria I. Arenas, Maria J. Blanquez, Ricardo Paniagua, Oscar M. Tirado, Vicente Notario

Cancer Res (2006) 66 (8_Supplement): 78.

Published: 15 April 2006

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Journal Articles

Roscovitine Is an Effective Inducer of Apoptosis of Ewing's Sarcoma Family Tumor Cells In vitro and In vivo

Oscar M. Tirado, Silvia Mateo-Lozano, Vicente Notario

Cancer Res (2005) 65 (20): 9320–9327.

DOI: https://doi.org/10.1158/0008-5472.CAN-05-1276

Published: 17 October 2005

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Journal Articles

The PCPH oncoprotein mediates cisplatin resistance through activation of PKCα and stabilization of the Bcl-2 protein in mouse fibroblasts

Oscar M. Tirado, Silvia Mateo-Lozano, Sean Sanders, Vishal Saxena, Vicente Notario

Cancer Res (2004) 64 (7_Supplement): 1158.

Published: 01 April 2004

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Journal Articles

Induction of apoptosis in Ewing’s Sarcoma cells by simultaneous treatment with antisense oligodeoxynucleotides (AS-ODNs) to the EWS/FLI-1 gene and Rapamycin

Silvia Mateo-Lozano, Oscar M. Tirado, Vicente Notario

Cancer Res (2004) 64 (7_Supplement): 682–683.

Published: 01 April 2004

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Journal Articles

The PCPH Oncoprotein Antagonizes the Proapoptotic Role of the Mammalian Target of Rapamycin in the Response of Normal Fibroblasts to Ionizing Radiation

Oscar M. Tirado, Silvia Mateo-Lozano, Sean Sanders, Luis E. Dettin, Vicente Notario

Cancer Res (2003) 63 (19): 6290–6298.

Published: 14 October 2003

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Journal Articles

Partial Depletion of Intracellular ATP Mediates the Stress-Survival Function of the PCPH Oncoprotein

Juán A. Recio, J. Guillermo Páez, Sean Sanders, Toshiaki Kawakami, Vicente Notario

Cancer Res (2002) 62 (9): 2690–2694.

Published: 01 May 2002

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Journal Articles

Both Normal and Transforming PCPH Proteins Have Guanosine Diphosphatase Activity But Only the Oncoprotein Cooperates with Ras in Activating Extracellular Signal-regulated Kinase ERK1

Juan A. Recio, J. Guillermo Páez, Baishali Maskeri, Mark Loveland, Juan A. Velasco, Vicente Notario

Cancer Res (2000) 60 (6): 1720–1728.

Published: 01 March 2000

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Journal Articles

Radiation-induced Apoptosis of Ewing's Sarcoma Cells: DNA Fragmentation and Proteolysis of Poly(ADP-ribose) Polymerase

Viatcheslav A. Soldatenkov, Sarada Prasad, Vicente Notario, Anatoly Dritschilo

Cancer Res (1995) 55 (19): 4240–4242.

Published: 01 October 1995

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Journal Articles

Enhanced Expression of Calreticulin in the Nucleus of Radioresistant Squamous Carcinoma Cells in Response to Ionizing Radiation

Priya Ramsamooj, Vicente Notario, Anatoly Dritschilo

Cancer Res (1995) 55 (14): 3016–3021.

Published: 01 July 1995

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Journal Articles

3-Methylcholanthrene Inactivates the p53 Gene in Syrian Hamster Embryo Fibroblasts by Inducing a Specific Intronic Point Mutation

Amador Albor, Denise M. Flessate, Thierry Soussi, Vicente Notario

Cancer Res (1994) 54 (16): 4502–4507.

Published: 01 August 1994

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NARROW

Abstract 1429: Forkhead box M1 (FoxM1) is a direct transcriptional target of EWS/FLI1 and a regulator of Ewing's sarcoma cell morphology, adhesiveness and tumorigenicity

Abstract 3405: Caveolin-1 modulates the metastatic ability of Ewing's sarcoma

Abstract #4930: GM2 synthase/GM3 synthase knockout transformed fibroblasts: a tumor model of complete ganglioside depletion

PCPH/ENTPD5 Expression Confers to Prostate Cancer Cells Resistance against Cisplatin-Induced Apoptosis through Protein Kinase Cα–Mediated Bcl-2 Stabilization

PCPH/ENTPD5 Expression Enhances the Invasiveness of Human Prostate Cancer Cells by a Protein Kinase Cδ–Dependent Mechanism

Meriolins, a New Class of Cell Death–Inducing Kinase Inhibitors with Enhanced Selectivity for Cyclin-Dependent Kinases

Expression of the PCPH oncogene enhances the invasiness of prostate cancer cells by a PKCδ-dependent mechanism.

Caveolin-1 (CAV1) Is a Target of EWS/FLI-1 and a Key Determinant of the Oncogenic Phenotype and Tumorigenicity of Ewing's Sarcoma Cells

Caveolin-1 is a target of EWS/FLI-1 and a key determinant of tumorigenicity and resistance to chemotherapy-induced apoptosis of Ewing's sarcoma cells.

Combination therapy targeting the EWS/FLI-1 oncogene with antisense oligonucleotides and rapamycin induces apoptosis of Ewing’s sarcoma cells in vitro and inhibits tumor growth in vivo

PCPH is differentially expressed in samples of benign and neoplastic human prostate, and contributes to maintaining the malignant phenotype of human prostate cancer cells

Roscovitine Is an Effective Inducer of Apoptosis of Ewing's Sarcoma Family Tumor Cells In vitro and In vivo

The PCPH oncoprotein mediates cisplatin resistance through activation of PKCα and stabilization of the Bcl-2 protein in mouse fibroblasts

Induction of apoptosis in Ewing’s Sarcoma cells by simultaneous treatment with antisense oligodeoxynucleotides (AS-ODNs) to the EWS/FLI-1 gene and Rapamycin

The PCPH Oncoprotein Antagonizes the Proapoptotic Role of the Mammalian Target of Rapamycin in the Response of Normal Fibroblasts to Ionizing Radiation

Partial Depletion of Intracellular ATP Mediates the Stress-Survival Function of the PCPH Oncoprotein

Both Normal and Transforming PCPH Proteins Have Guanosine Diphosphatase Activity But Only the Oncoprotein Cooperates with Ras in Activating Extracellular Signal-regulated Kinase ERK1

Radiation-induced Apoptosis of Ewing's Sarcoma Cells: DNA Fragmentation and Proteolysis of Poly(ADP-ribose) Polymerase

Enhanced Expression of Calreticulin in the Nucleus of Radioresistant Squamous Carcinoma Cells in Response to Ionizing Radiation

3-Methylcholanthrene Inactivates the p53 Gene in Syrian Hamster Embryo Fibroblasts by Inducing a Specific Intronic Point Mutation

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