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Vernon E. Steele
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Journal Articles

Abstract 5065: Pharmacological modulation of inflammation and p53 signaling synergize to prevents muscle invasive bladder cancer in-vivo

Venkateshwar Madka, Yuting Zhang, Nandini Kumar, Gopal Pathuri, Nicole Stratton, Stanley Lightfoot, Adam S. Asch, Vernon E. Steele, Altaf Mohammed, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5065.
https://doi.org/10.1158/1538-7445.AM2019-5065
Published: 01 July 2019
View articletitled, Abstract 5065: Pharmacological modulation of inflammation and p53 signaling synergize to prevents muscle invasive bladder cancer in-vivo
Journal Articles

Abstract 4983: Intermittent dosing regimens of naproxen and aspirin inhibit azoxymethane-induced rat colon adenoma progression to adenocarcinoma and carcinoma invasion

Altaf Mohammed, Naveena B. Janakiram, Venkateshwar Madka, Yuting Zhang, Anil Singh, Laura Biddick, Qian Li, Stan Lightfoot, Vernon E. Steele, Ronald Lubet, Mark S. Miller, Chen S. Suen, Shizuko Sei, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4983.
https://doi.org/10.1158/1538-7445.AM2018-4983
Published: 01 July 2018
View articletitled, Abstract 4983: Intermittent dosing regimens of naproxen and aspirin inhibit azoxymethane-induced rat colon adenoma progression to adenocarcinoma and carcinoma invasion
Journal Articles

Abstract 5260: NGS Transcriptome analysis of colon adenocarcinomas treated with individual and combination of aspirin and omeprazole

Naveena B. Janakiram, Altaf Mohammed, Jagan M.R. Patlolla, Yuting Zhang, Laura Biddick, Venkateshwar Madka, Li Qian, Stan Lightfoot, Barbara Dunn, Ronald Lubet, Chen S. Suen, Vernon E. Steele, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5260.
https://doi.org/10.1158/1538-7445.AM2017-5260
Published: 01 July 2017
View articletitled, Abstract 5260: NGS Transcriptome analysis of colon adenocarcinomas treated with individual and combination of aspirin and omeprazole
Journal Articles

Abstract 5246: Effects of bazedoxifene either alone or in combination with letrozole in the prevention of chemically induced mammary cancers

Barbara K. Dunn, Chen Suen, Ronald A. Lubet, Vernon E. Steele, Clinton J. Grubbs
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5246.
https://doi.org/10.1158/1538-7445.AM2017-5246
Published: 01 July 2017
View articletitled, Abstract 5246: Effects of bazedoxifene either alone or in combination with letrozole in the prevention of chemically induced mammary cancers
Journal Articles

Abstract 2625: Simultaneous targeting of ODC and 5-LOX/COX block the tobacco carcinogen-induced lung adenoma progression to adenocarcinoma in A/J mice

Gaurav Kumar, Jagan Mohan R. Patolla, Venkateshwar Madka, Altaf Mohammed, Li Qian, Yuting Zhang, Laura Biddick, Anil Singh, Allison Gillaspy, Stanley Lightfoot, Levy Kopelovich, Vernon E. Steele, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2625.
https://doi.org/10.1158/1538-7445.AM2016-2625
Published: 15 July 2016
View articletitled, Abstract 2625: Simultaneous targeting of ODC and 5-LOX/COX block the tobacco carcinogen-induced lung adenoma progression to adenocarcinoma in A/J mice
Journal Articles

Abstract 2626: Metabolic profiles and potential pharmacodynamic biomarkers in female Sprague-Dawley rats on a standard (4% fat) or Western (20% fat) diet and treated with known active or inactive chemopreventive agents

Matthew D. Thompson, Clinton J. Grubbs, Vernon E. Steele, Mark S. Miller, Fariba Moeinpour, Edward D. Karoly, Ronald A. Lubet
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2626.
https://doi.org/10.1158/1538-7445.AM2016-2626
Published: 15 July 2016
View articletitled, Abstract 2626: Metabolic profiles and potential pharmacodynamic biomarkers in female Sprague-Dawley rats on a standard (4% fat) or Western (20% fat) diet and treated with known active or inactive chemopreventive agents
Journal Articles

Abstract 5255: Lack of chemopreventive effects of dietary P2×7R inhibitors against pancreatic cancer in p48Cre/+-LSL-KrasG12D/+ mice

Altaf Mohammed, Naveena B. Janakiram, Venkateshwar Madka, Gopal Pathuri, Qian Li, Rebekah Ritchie, Laura Biddick, Hannah Kutsche, Yuting Zhang, Anil Singh, Hariprasad Gali, Stan Lightfoot, Vernon E. Steele, Chen S. Suen, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5255.
https://doi.org/10.1158/1538-7445.AM2016-5255
Published: 15 July 2016
View articletitled, Abstract 5255: Lack of chemopreventive effects of dietary P2×7R inhibitors against pancreatic cancer in p48Cre/+-LSL-KrasG12D/+ mice
Journal Articles

Abstract 824: Effects of metfornin on mammary carcinogenesis and metabolic profiles in methylnitrosourea-treated rats on standard or Western diets

Mark S. Miller, Matthew D. Thompson, Ronald A. Lubet, Vernon E. Steele, Harold E. Seifried, Clinton J. Grubbs
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 824.
https://doi.org/10.1158/1538-7445.AM2016-824
Published: 15 July 2016
View articletitled, Abstract 824: Effects of metfornin on mammary carcinogenesis and metabolic profiles in methylnitrosourea-treated rats on standard or Western diets
Journal Articles

Abstract 837: Reproducibility of efficacy results for chemopreventive agents in the methylnitrosourea-induced rat mammary cancer model

Vernon E. Steele, Ronald A. Lubet, Clinton J. Grubbs
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 837.
https://doi.org/10.1158/1538-7445.AM2016-837
Published: 15 July 2016
View articletitled, Abstract 837: Reproducibility of efficacy results for chemopreventive agents in the methylnitrosourea-induced rat mammary cancer model
Journal Articles

Abstract 2813: Chemoprevention of mammary cancer: Modeling predictive values of short-term morphologic assays for efficacy in animal tumor assays

Barbara K. Dunn, Vernon E. Steele, Richard M. Fagerstrom, Carol F. Topp, Barnett S. Kramer
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2813.
https://doi.org/10.1158/1538-7445.AM2015-2813
Published: 01 August 2015
View articletitled, Abstract 2813: Chemoprevention of mammary cancer: Modeling predictive values of short-term morphologic assays for efficacy in animal tumor assays
Journal Articles

Abstract 2819: Targeting inflammation and pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression

Altaf Mohammed, Naveena B. Janakiram, Venkateshwar Madka, Misty Brewer, Rebekah L. Ritchie, Stan Lightfoot, Gaurav Kumar, Michael Sadeghi, Jagan Mohan R Patlolla, Hiroshi Yamada, Zobeida Cruz-Monserrate, Courtney W. Houchen, Vernon E. Steele, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2819.
https://doi.org/10.1158/1538-7445.AM2015-2819
Published: 01 August 2015
View articletitled, Abstract 2819: Targeting inflammation and pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression
Journal Articles

Abstract 2809: Chemopreventive studies of multiple agents in the methylnitrosourea-induced ER+ mammary cancer model in animals on standard and Western diets

Clinton J. Grubbs, Mark S. Miller, Vernon E. Steele, Fariba Moeinpour, Harold Seifried, Brandy M. Heckman-Stoddard, Ronald A. Lubet
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2809.
https://doi.org/10.1158/1538-7445.AM2015-2809
Published: 01 August 2015
View articletitled, Abstract 2809: Chemopreventive studies of multiple agents in the methylnitrosourea-induced ER+ mammary cancer model in animals on standard and Western diets
Journal Articles

Abstract 2820: Omeprazole alone, or in combination with Aspirin inhibits azoxymethane-induced colon adenoma progression to adenocarcinoma and carcinoma invasion in F344 rat model

Altaf Mohammed, Jagan M.R Patlolla, Yuting Zhang, Laura Biddick, Venkateshwar Madka, Qian Li, Stan Lightfoot, Ronald Lubet, Chen S. Suen, Vernon E. Steele, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2820.
https://doi.org/10.1158/1538-7445.AM2015-2820
Published: 01 August 2015
View articletitled, Abstract 2820: Omeprazole alone, or in combination with Aspirin inhibits azoxymethane-induced colon adenoma progression to adenocarcinoma and carcinoma invasion in F344 rat model
Journal Articles

Abstract P5-11-06: Understanding predictive values of short-term morphologic assays of cancer chemoprevention for efficacy in animal mammary gland tumor assays

Barbara K Dunn, Vernon E Steele, Carol F Topp, Richard M Fagerstrom, Barnett S Kramer
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P5-11-06.
https://doi.org/10.1158/1538-7445.SABCS14-P5-11-06
Published: 01 May 2015
View articletitled, Abstract P5-11-06: Understanding predictive values of short-term morphologic assays of cancer chemoprevention for efficacy in animal mammary gland tumor assays
Journal Articles

Abstract P5-11-01: Correlation of the effects of potential and known chemopreventive agents on proliferation rates in normal mammary glands and mammary cancers with their chemopreventive efficacy

Brandy M Heckman-Stoddard, Clinton J Grubbs, Fariba Moeinpour, Vernon E Steele, Ronald A Lubet
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P5-11-01.
https://doi.org/10.1158/1538-7445.SABCS14-P5-11-01
Published: 01 May 2015
View articletitled, Abstract P5-11-01: Correlation of the effects of potential and known chemopreventive agents on proliferation rates in normal mammary glands and mammary cancers with their chemopreventive efficacy
Journal Articles

Abstract 2969: Combinational Targeting of EGFR and ODC pathways by Gefitinib and DFMO lead to complete blockade of PanIN progression to pancreatic ductal adenocarcinoma

Altaf Mohammed, Naveena B. Janakiram, Rebekah L. Ritchie, Laura Biddick, Misty Brewer, Stan Lightfoot, Vernon E. Steele, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2969.
https://doi.org/10.1158/1538-7445.AM2014-2969
Published: 01 October 2014
View articletitled, Abstract 2969: Combinational Targeting of EGFR and ODC pathways by Gefitinib and DFMO lead to complete blockade of PanIN progression to pancreatic ductal adenocarcinoma
Journal Articles

Abstract 2145: Chemopreventive and immune-modulatory effects of the Cucumaria frondosa extract, Frondanol A5 in the APCMin/+ mice intestinal tumorigenesis

Naveena B. Janakiram, Altaf Mohammed, Misty Brewer, Peter D. Collin, Vernon E. Steele, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2145.
https://doi.org/10.1158/1538-7445.AM2014-2145
Published: 01 October 2014
View articletitled, Abstract 2145: Chemopreventive and immune-modulatory effects of the Cucumaria frondosa extract, Frondanol A5 in the APCMin/+ mice intestinal tumorigenesis
Journal Articles

Abstract 2135: Chemoprevention of tobacco carcinogen-induced lung cancer by DFMO and Licofelone administered individually or in combination in female A/J mice

Jagan Mohan Reddy Patlolla, Levy Kopelovich, Li Qian, Laura Biddick, Yuting Zhang, Michael K. Sadeghi, Dhimant Desai, Shantu Amin, Stan Lightfoot, Vernon E. Steele, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2135.
https://doi.org/10.1158/1538-7445.AM2014-2135
Published: 01 October 2014
View articletitled, Abstract 2135: Chemoprevention of tobacco carcinogen-induced lung cancer by DFMO and Licofelone administered individually or in combination in female A/J mice
Journal Articles

Abstract 2268: Metformin prevents progression of pancreatic intraepithelial neoplasia to ductal adenocarcinoma by targeting cancer stem cells and mTOR signaling.

Altaf Mohammed, Misty Brewer, Rebekah L. Ritchie, Anuj Marya, Stan Lightfoot, Naveena B. Janakiram, Vernon E. Steele, Chinthalapally V. Rao
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2268.
https://doi.org/10.1158/1538-7445.AM2013-2268
Published: 15 April 2013
View articletitled, Abstract 2268: Metformin prevents progression of pancreatic intraepithelial neoplasia to ductal adenocarcinoma by targeting cancer stem cells and mTOR signaling.
Journal Articles

Abstract 2595: Predictive value tools as an aid in chemopreventive agent development.

Barbara K. Dunn, Vernon E. Steele, Richard M. Fagerstrom, Carol F. Topp, David Ransohoff, Christopher Cunningham, Ronald A. Lubet, Leslie G. Ford, Barnett S. Kramer
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2595.
https://doi.org/10.1158/1538-7445.AM2013-2595
Published: 15 April 2013
View articletitled, Abstract 2595: Predictive value tools as an aid in chemopreventive agent development.