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Valeriana Di Castro
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Journal Articles

Abstract 1197: Endothelin-1 receptor/β-arrestin1 is an actionable node that regulates YAP/TAZ signaling and chemoresistance in high-grade ovarian cancer

Piera Tocci, Roberta Cianfrocca, Laura Rosanò, Rosanna Sestito, Valeriana Di Castro, Giovanni Blandino, Anna Bagnato
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1197.
https://doi.org/10.1158/1538-7445.AM2017-1197
Published: 01 July 2017
View articletitled, Abstract 1197: Endothelin-1 receptor/β-arrestin1 is an actionable node that regulates YAP/TAZ signaling and chemoresistance in high-grade ovarian cancer
Journal Articles

Abstract 2901: Nuclear β-arrestin1 is a critical cofactor of hypoxia-inducible factor-1α signaling in endothelin-1-induced ovarian tumor progression

Piera Tocci, Roberta Cianfrocca, Laura Rosanò, Valentina Caprara, Rosanna Sestito, Valeriana Di Castro, Anna Bagnato
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2901.
https://doi.org/10.1158/1538-7445.AM2016-2901
Published: 15 July 2016
View articletitled, Abstract 2901: Nuclear β-arrestin1 is a critical cofactor of hypoxia-inducible factor-1α signaling in endothelin-1-induced ovarian tumor progression
Journal Articles

Abstract 3580: Downregulated miR-30a promotes acquisition of chemoresistance by targeting endothelin A receptor in ovarian carcinoma

Rosanna Sestito, Roberta Cianfrocca, Laura Rosanò, Elisa Semprucci, Piera Tocci, Valeriana Di Castro, Gabriella Ferrandina, Anna Bagnato
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3580.
https://doi.org/10.1158/1538-7445.AM2015-3580
Published: 01 August 2015
View articletitled, Abstract 3580: Downregulated miR-30a promotes acquisition of chemoresistance by targeting endothelin A receptor in ovarian carcinoma
Journal Articles

Endothelin A Receptor/β-Arrestin Signaling to the Wnt Pathway Renders Ovarian Cancer Cells Resistant to Chemotherapy

Laura Rosanò, Roberta Cianfrocca, Piera Tocci, Francesca Spinella, Valeriana Di Castro, Valentina Caprara, Elisa Semprucci, Gabriella Ferrandina, Pier Giorgio Natali, Anna Bagnato
Journal: Cancer Research
Cancer Res (2014) 74 (24): 7453–7464.
https://doi.org/10.1158/0008-5472.CAN-13-3133
Published: 14 December 2014
View articletitled, Endothelin A Receptor/β-Arrestin Signaling to the Wnt Pathway Renders Ovarian Cancer Cells Resistant to Chemotherapy
Open the PDF for Endothelin A Receptor/β-Arrestin Signaling to the Wnt Pathway Renders Ovarian Cancer Cells Resistant to Chemotherapy in another window
Includes: Supplementary data
Journal Articles

Abstract 3144: PDZ-RhoGEF/β-arrestin-1 interaction mediates endothelin A receptor-induced RhoA activation and cell motility in ovarian tumor cells

Piera Tocci, Roberta Cianfrocca, Elisa Semprucci, Valeriana Di Castro, Anna Bagnato, Laura Rosanò
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3144.
https://doi.org/10.1158/1538-7445.AM2014-3144
Published: 01 October 2014
View articletitled, Abstract 3144: PDZ-RhoGEF/β-arrestin-1 interaction mediates endothelin A receptor-induced RhoA activation and cell motility in ovarian tumor cells
Journal Articles

Abstract 756: Endothelin-induced multifunctional complex regulates β-arrestin-1 nuclear activity to promote EMT in chemoresistant ovarian cancer cells.

Laura Rosanò, Roberta Cianfrocca, Piera Tocci, Elisa Semprucci, Francesca Spinella, Valeriana Di Castro, Anna Bagnato
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 756.
https://doi.org/10.1158/1538-7445.AM2013-756
Published: 15 April 2013
View articletitled, Abstract 756: Endothelin-induced multifunctional complex regulates β-arrestin-1 nuclear activity to promote EMT in chemoresistant ovarian cancer cells.
Journal Articles

Abstract 3086: α-arrestin-1 acts as a nuclear transcriptional regulator of endothelin A receptor signalling to promote ovarian cancer progression

Laura Rosanò, Roberta Cianfrocca, Piera Tocci, Francesca Spinella, Valeriana Di Castro, Erica Salvati, Anna Maria Biroccio, Pier Giorgio Natali, Anna Bagnato
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3086.
https://doi.org/10.1158/1538-7445.AM2012-3086
Published: 15 April 2012
View articletitled, Abstract 3086: α-arrestin-1 acts as a nuclear transcriptional regulator of endothelin A receptor signalling to promote ovarian cancer progression
Journal Articles

Abstract 707: Acquisition of chemoresistance and epithelial to mesenchymal phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells

Roberta Cianfrocca, Laura Rosanò, Valeriana Di Castro, Francesca Spinella, Maria Rita Nicotra, Alessandro Lucidi, Gabriella Ferrandina, Pier Giorgio Natali, Anna Bagnato
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 707.
https://doi.org/10.1158/1538-7445.AM2011-707
Published: 15 April 2011
View articletitled, Abstract 707: Acquisition of chemoresistance and epithelial to mesenchymal phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells
Journal Articles

Abstract 698: β-arrestin-1 as nuclear signalling element essential for endothelin A receptor-induced epithelial to mesenchymal transition and chemoresistance

Laura Rosanò, Roberta Cianfrocca, Valeriana Di Castro, Francesca Spinella, Maria Rita Nicotra, Pier Giorgio Natali, Anna Bagnato
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 698.
https://doi.org/10.1158/1538-7445.AM2011-698
Published: 15 April 2011
View articletitled, Abstract 698: β-arrestin-1 as nuclear signalling element essential for endothelin A receptor-induced epithelial to mesenchymal transition and chemoresistance
Journal Articles

Abstract 2551: Acquisition of epithelial-mesenchymal transition phenotype of chemoresistant ovarian cancer cells is linked with activation of the endothelin signaling pathway

Roberta Cianfrocca, Laura Rosanò, Valeriana Di Castro, Francesca Spinella, Maria Rita Nicotra, Gabriella Ferrandina, Pier Giorgio Natali, Anna Bagnato
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2551.
https://doi.org/10.1158/1538-7445.AM10-2551
Published: 15 April 2010
View articletitled, Abstract 2551: Acquisition of epithelial-mesenchymal transition phenotype of chemoresistant ovarian cancer cells is linked with activation of the endothelin signaling pathway
Journal Articles

Abstract 2363: Positive inter-regulation between β-catenin and endothelin signaling in ovarian cancer cells: Epigenetic regulation of gene transcription

Laura Rosanò, Roberta Cianfrocca, Valeriana Di Castro, Francesca Spinella, Maria Rita Nicotra, Pier Giorgio Natali, Anna Bagnato
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2363.
https://doi.org/10.1158/1538-7445.AM10-2363
Published: 15 April 2010
View articletitled, Abstract 2363: Positive inter-regulation between β-catenin and endothelin signaling in ovarian cancer cells: Epigenetic regulation of gene transcription
Journal Articles

Abstract #5311: A nuclear function of \#946; -arrestin-1 in endothelin A receptor signaling in human ovarian carcinoma cells: Therapeutic implications

Laura Rosanò, Stefano Masi, Roberta Cianfrocca, Francesca Spinella, Valeriana Di Castro, Maria Rita Nicotra, Pier Giorgio Natali, Anna Bagnato
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5311.
Published: 01 May 2009
View articletitled, Abstract #5311: A nuclear function of \#946; -arrestin-1 in endothelin A receptor signaling in human ovarian carcinoma cells: Therapeutic implications
Journal Articles

Endothelin-1 Stimulates Lymphatic Endothelial Cells and Lymphatic Vessels to Grow and Invade

Francesca Spinella, Emirena Garrafa, Valeriana Di Castro, Laura Rosanò, Maria Rita Nicotra, Arnaldo Caruso, Pier Giorgio Natali, Anna Bagnato
Journal: Cancer Research
Cancer Res (2009) 69 (6): 2669–2676.
https://doi.org/10.1158/0008-5472.CAN-08-1879
Published: 17 March 2009
View articletitled, Endothelin-1 Stimulates Lymphatic Endothelial Cells and Lymphatic Vessels to Grow and Invade
Open the PDF for Endothelin-1 Stimulates Lymphatic Endothelial Cells and Lymphatic Vessels to Grow and Invade in another window
Includes: Supplementary data
Journal Articles

Endothelin A receptor promotes ovarian cancer metastasis: implications for an effective targeted-therapy

Laura Rosano, Stefano Masi, Roberta Cianfrocca, Francesca Spinella, Valeriana Di Castro, Maria Rita Nicotra, Pier Giorgio Natali, Anna Bagnato
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2574.
Published: 01 May 2008
View articletitled, Endothelin A receptor promotes ovarian cancer metastasis: implications for an effective targeted-therapy
Journal Articles

Emerging role of endothelin axis in lymphangiogenesis

Francesca Spinella, Emirena Garrafa, Arnaldo Caruso, Valeriana Di Castro, Laura Rosano, Pier Giorgio Natali, Anna Bagnato
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 375.
Published: 01 May 2008
View articletitled, Emerging role of endothelin axis in lymphangiogenesis
Journal Articles

Combined Targeting of Endothelin A Receptor and Epidermal Growth Factor Receptor in Ovarian Cancer Shows Enhanced Antitumor Activity

Laura Rosanò, Valeriana Di Castro, Francesca Spinella, Giampaolo Tortora, Maria Rita Nicotra, Pier Giorgio Natali, Anna Bagnato
Journal: Cancer Research
Cancer Res (2007) 67 (13): 6351–6359.
https://doi.org/10.1158/0008-5472.CAN-07-0883
Published: 06 July 2007
View articletitled, Combined Targeting of Endothelin A Receptor and Epidermal Growth Factor Receptor in Ovarian Cancer Shows Enhanced Antitumor Activity
Open the PDF for Combined Targeting of Endothelin A Receptor and Epidermal Growth Factor Receptor in Ovarian Cancer Shows Enhanced Antitumor Activity in another window
Journal Articles

Endothelins regulates transcription of cyclooxygenase-2 via hypoxia-inducible factor-1α in melanoma progression

Francesca Spinella, Laura Rosano, Valeriana Di Castro, Maria Rita Nicotra, Pier Giorgio Natali, Anna Bagnato
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2150.
Published: 01 May 2007
View articletitled, Endothelins regulates transcription of cyclooxygenase-2 via hypoxia-inducible factor-1α in melanoma progression
Journal Articles

β-Arrestin 1 as messenger of endothelin A receptor to mediate β-catenin signaling and epithelial to mesenchymal transition in human ovarian cancer cells

Laura Rosano, Francesca Spinella, Valeriana Di Castro, Stefano Masi, Maria Rita Nicotra, Pier Giorgio Natali, Anna Bagnato
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 5636.
Published: 01 May 2007
View articletitled, β-Arrestin 1 as messenger of endothelin A receptor to mediate β-catenin signaling and epithelial to mesenchymal transition in human ovarian cancer cells
Journal Articles

Endothelin-1 and Endothelin-3 Promote Invasive Behavior via Hypoxia-Inducible Factor-1α in Human Melanoma Cells

Francesca Spinella, Laura Rosanò, Valeriana Di Castro, Samantha Decandia, Maria Rita Nicotra, Pier Giorgio Natali, Anna Bagnato
Journal: Cancer Research
Cancer Res (2007) 67 (4): 1725–1734.
https://doi.org/10.1158/0008-5472.CAN-06-2606
Published: 16 February 2007
View articletitled, Endothelin-1 and Endothelin-3 Promote Invasive Behavior via Hypoxia-Inducible Factor-1α in Human Melanoma Cells
Open the PDF for Endothelin-1 and Endothelin-3 Promote Invasive Behavior via Hypoxia-Inducible Factor-1α in Human Melanoma Cells in another window
Includes: Supplementary data
Journal Articles

Inhibition of vascular endothelial growth factor expression and invasive behavior in human malignant melanoma by targeting the endothelin B receptor.

Francesca Spinella, Laura Rosanò, Samantha Decandia, Valeriana Di Castro, Pier Giorgio Natali*, Anna Bagnato
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1287–1288.
Published: 15 April 2006
View articletitled, Inhibition of vascular endothelial growth factor expression and invasive behavior in human malignant melanoma by targeting the endothelin B receptor.