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V. Ashutosh Rao
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Journal Articles

Abstract 5352: Acute total body ionizing radiation induces long-term cardiac effects and immediate changes in oxidative carbonylation of cardiac proteins in the rat

Elliot T. Rosen, Dmitry Kryndushkin, Baikuntha Aryal, Yanira Gonzalez, Leena Chehab, Jennifer Dickey, V. Ashutosh Rao
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5352.
https://doi.org/10.1158/1538-7445.AM2020-5352
Published: 15 August 2020
View article titled, Abstract 5352: Acute total body ionizing radiation induces long-term cardiac effects and immediate changes in oxidative carbonylation of cardiac proteins in the rat
Journal Articles

Targeting Mitochondrial Fission to Trigger Cancer Cell Death

V. Ashutosh Rao
Journal: Cancer Research
Cancer Res (2019) 79 (24): 6074–6075.
https://doi.org/10.1158/0008-5472.CAN-19-3276
Published: 13 December 2019
View article titled, Targeting Mitochondrial Fission to Trigger Cancer Cell Death
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Journal Articles

Abstract 5141: T-cell receptor repertoire analysis by next-generation sequencing peripheral blood mononuclear cells from multiple myeloma or smoldering multiple myeloma patients

Yong Zhang, Svetlana Petrovskaya, Emma C. Scott, Luis Santana-Quintero, Tigran Ghazanchyan, Amy Rosenburg, V. Ashutosh Rao, Gideon M. Blumenthal, Marc Theoret, Richard Pazdur, Julia A. Beaver, Dickran Kazandjian
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5141.
https://doi.org/10.1158/1538-7445.AM2019-5141
Published: 01 July 2019
View article titled, Abstract 5141: T-cell receptor repertoire analysis by next-generation sequencing peripheral blood mononuclear cells from multiple myeloma or smoldering multiple myeloma patients
Journal Articles

Abstract 3516: A genomics model to predict immune-related adverse events in cancer patients treated with checkpoint inhibitors

Emma C. Scott, Dickran Kazandjian, Luis Santana-Quintero, Tigran Ghazanchyan, Svetlana Petrovskaya, Yong Zhang, Amy Rosenberg, V. Ashutosh Rao, Jennifer L. Marte, Gideon M. Blumenthal, Marc R. Theoret, Richard Pazdur, James L. Gulley, Julia A. Beaver
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3516.
https://doi.org/10.1158/1538-7445.AM2019-3516
Published: 01 July 2019
View article titled, Abstract 3516: A genomics model to predict immune-related adverse events in cancer patients treated with checkpoint inhibitors
Journal Articles

Abstract 70: Oxidative stress and cell death in multidrug-resistant cancer

Baikuntha P. Aryal, Jean-Pierre Gillet, V Ashutosh Rao
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 70.
https://doi.org/10.1158/1538-7445.AM2019-70
Published: 01 July 2019
View article titled, Abstract 70: Oxidative stress and cell death in multidrug-resistant cancer
Journal Articles

Abstract 3940: Acute total body ionizing radiation induces long-term adverse effects and immediate changes in cardiac protein oxidative carbonylation in the rat

Elliot T. Rosen, Dmitry Kryndushkin, Baikuntha Aryal, Yanira Gonzalez, Leena Chehab, Jennifer Dickey, Steven Mog, V Ashutosh Rao
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3940.
https://doi.org/10.1158/1538-7445.AM2019-3940
Published: 01 July 2019
View article titled, Abstract 3940: Acute total body ionizing radiation induces long-term adverse effects and immediate changes in cardiac protein oxidative carbonylation in the rat
Journal Articles

Abstract 5842: Oxidative stress and protein carbonylation towards multi-drug resistance in cancer

Baikuntha P. Aryal, Jean-Pierre Gillet, V Ashutosh Rao
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5842.
https://doi.org/10.1158/1538-7445.AM2018-5842
Published: 01 July 2018
View article titled, Abstract 5842: Oxidative stress and protein carbonylation towards multi-drug resistance in cancer
Journal Articles

Abstract 845: Acute irradiation exposure induces long-term cardiac adverse effects in the spontaneously hypertensive rat

Elliot T. Rosen, Dmitry Kryndushkin, Baikuntha Aryal, Yanira Gonzalez, Leena Chehab, Jennifer Dickey, Steven Mog, V Ashutosh Rao
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 845.
https://doi.org/10.1158/1538-7445.AM2018-845
Published: 01 July 2018
View article titled, Abstract 845: Acute irradiation exposure induces long-term cardiac adverse effects in the spontaneously hypertensive rat
Journal Articles

Abstract 2917: Therapeutic targeting of the mitochondria: An evaluation of the transcriptional link between the antioxidant response and autophagy

Kaytee L. Pokrzywinski, Francesca Mascia, V. Ashutosh Rao.
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2917.
https://doi.org/10.1158/1538-7445.AM2016-2917
Published: 15 July 2016
View article titled, Abstract 2917: Therapeutic targeting of the mitochondria: An evaluation of the transcriptional link between the antioxidant response and autophagy
Journal Articles

Abstract 3005: The impact of mitochondrially targeted oncology agents on mitochondrial DNA (mtDNA) integrity

Kaytee L. Pokrzywinski, Thomas G. Biel, Dmitry Kryndushkin, V. Ashutosh Rao.
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3005.
https://doi.org/10.1158/1538-7445.AM2016-3005
Published: 15 July 2016
View article titled, Abstract 3005: The impact of mitochondrially targeted oncology agents on mitochondrial DNA (mtDNA) integrity
Journal Articles

Abstract 1090: microRNA regulation of Nrf2 and the antioxidant response in breast cancer cells following redox therapy

Francesca Mascia, Kaytee L. Pokrzywinski, V. Ashutosh Rao.
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1090.
https://doi.org/10.1158/1538-7445.AM2016-1090
Published: 15 July 2016
View article titled, Abstract 1090: microRNA regulation of Nrf2 and the antioxidant response in breast cancer cells following redox therapy
Journal Articles

Abstract 4640: Doxorubicin induced cardiomyopathy associated with natural reproductive hormone cycling in female tumor-bearing spontaneously hypertensive rats

Kaytee L. Pokrzywinski, Elliot T. Rosen, Julia Bonnano, Thomas Biel, Delaram Moshkelani, Baikuntha Aryal, Steven Mog, V. Ashutosh Rao
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4640.
https://doi.org/10.1158/1538-7445.AM2016-4640
Published: 15 July 2016
View article titled, Abstract 4640: Doxorubicin induced cardiomyopathy associated with natural reproductive hormone cycling in female tumor-bearing spontaneously hypertensive rats
Journal Articles

Abstract 4639: Reproductive hormone levels modulate doxorubicin induced cardiomyopathy in female tumor-bearing spontaneously hypertensive rats

Kaytee L. Pokrzywinski, Elliot T. Rosen, Julia Bonanno, Thomas Biel, Delaram Moshkelani, Baikuntha Aryal, Steven Mog, V. Ashutosh Rao
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4639.
https://doi.org/10.1158/1538-7445.AM2016-4639
Published: 15 July 2016
View article titled, Abstract 4639: Reproductive hormone levels modulate doxorubicin induced cardiomyopathy in female tumor-bearing spontaneously hypertensive rats
Journal Articles

Abstract 2554: Doxorubicin induced gender differences in tumor-bearing spontaneously hypertensive rats, with an emphasis on cardiotoxicity

Kaytee L. Pokrzywinski, Yanira Gonzalez, Leena M. Chehab, Elliot T. Rosen, Vikrant Vijay, Varsha Desai, Jennifer S. Dickey, V. Ashutosh Rao
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2554.
https://doi.org/10.1158/1538-7445.AM2015-2554
Published: 01 August 2015
View article titled, Abstract 2554: Doxorubicin induced gender differences in tumor-bearing spontaneously hypertensive rats, with an emphasis on cardiotoxicity
Journal Articles

Abstract 1825: Carbonylation and degradation of cardiac myosin binding protein C serves as an indicator of doxorubicin-induced cardiotoxicity

Baikuntha P. Aryal, Jinsook Jeong, V. Ashutosh Rao
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1825.
https://doi.org/10.1158/1538-7445.AM2015-1825
Published: 01 August 2015
View article titled, Abstract 1825: Carbonylation and degradation of cardiac myosin binding protein C serves as an indicator of doxorubicin-induced cardiotoxicity
Journal Articles

Abstract LB-291: microRNA regulation of Nrf2: A link between autophagy and oxidative stress

Kaytee L. Pokrzywinski, V. Ashutosh Rao
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-291.
https://doi.org/10.1158/1538-7445.AM2015-LB-291
Published: 01 August 2015
View article titled, Abstract LB-291: microRNA regulation of Nrf2: A link between autophagy and oxidative stress
Journal Articles

Abstract 2496: Identification and functional characterization of a novel oxidatively modified protein in the cardiac tissue after doxorubicin-induced cardiotoxicity.

Baikuntha P. Aryal, Jinsook Jeong, V. Ashutosh Rao
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2496.
https://doi.org/10.1158/1538-7445.AM2013-2496
Published: 15 April 2013
View article titled, Abstract 2496: Identification and functional characterization of a novel oxidatively modified protein in the cardiac tissue after doxorubicin-induced cardiotoxicity.
Journal Articles

Abstract 4452: Induction of cell and autophagy by the anticancer redox agent mitoquinone is regulated by Nrf2

V. Ashutosh Rao, Sarah Klein, Naoko Mizuno, Jacek Zielonka, Balarama Kalyanaraman, Emily Shacter
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4452.
https://doi.org/10.1158/1538-7445.AM10-4452
Published: 15 April 2010
View article titled, Abstract 4452: Induction of cell and autophagy by the anticancer redox agent mitoquinone is regulated by Nrf2
Journal Articles

The Iron Chelator Dp44mT Causes DNA Damage and Selective Inhibition of Topoisomerase IIα in Breast Cancer Cells

V. Ashutosh Rao, Sarah R. Klein, Keli K. Agama, Eriko Toyoda, Noritaka Adachi, Yves Pommier, Emily B. Shacter
Journal: Cancer Research
Cancer Res (2009) 69 (3): 948–957.
https://doi.org/10.1158/0008-5472.CAN-08-1437
Published: 29 January 2009
View article titled, The Iron Chelator Dp44mT Causes DNA Damage and Selective Inhibition of Topoisomerase IIα in Breast Cancer Cells
Open the PDF for The Iron Chelator Dp44mT Causes DNA Damage and Selective Inhibition of Topoisomerase IIα in Breast Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Batracylin (NSC 320846), a Dual Inhibitor of DNA Topoisomerases I and II Induces Histone γ-H2AX as a Biomarker of DNA Damage

V. Ashutosh Rao, Keli Agama, Susan Holbeck, Yves Pommier
Journal: Cancer Research
Cancer Res (2007) 67 (20): 9971–9979.
https://doi.org/10.1158/0008-5472.CAN-07-0804
Published: 17 October 2007
View article titled, Batracylin (NSC 320846), a Dual Inhibitor of DNA Topoisomerases I and II Induces Histone γ-H2AX as a Biomarker of DNA Damage
Open the PDF for Batracylin (NSC 320846), a Dual Inhibitor of DNA Topoisomerases I and II Induces Histone γ-H2AX as a Biomarker of DNA Damage in another window
Includes: Supplementary data