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Umamaheswar Duvvuri
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Journal Articles

Abstract 5060: Role of molecular driver mutations in recurrence of early stage laryngeal cancer following narrow field definitive radiotherapy

Aaron Segura, Emily Nissen, Chris Lominska, Ryan Morse, Deri Morgan, Prakash Neupane, Dong Pei, Devin Koestler, Randall Kimple, Umamaheswar Duvvuri, Kevin Sykes, Sufi Thomas, Rohit Nallani, Lisa Shnayder, Kiran Kakarala, Emrullah Yilmaz, Andres Bur
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5060.
https://doi.org/10.1158/1538-7445.AM2024-5060
Published: 22 March 2024
View article titled, Abstract 5060: Role of molecular driver mutations in recurrence of early stage laryngeal cancer following narrow field definitive radiotherapy
Journal Articles

Abstract CT198: Immunomodulatory effects of the ATR inhibitor ceralasertib in a window of opportunity biomarker trial in patients with head and neck squamous cell carcinoma

Gemma N. Jones, Sonia Iyer, Marta Milo, Pei-Jen Lou, Melonie A. Nance, Carlos A. Gomez-Roca, Nathan Standifer, Paola Marco-Casanova, Shaan Gill, Michael Surace, Richard Bystry, Maria Alexandrova, Sophie Willis, Jaime Rodriguez-Canales, Andreas Dannhorn, Bienvenu Loembé, Alan Lau, Natalia Lukashchuk, Elizabeth A. Harrington, Elhan Sanai, Emma Dean, Umamaheswar Duvvuri
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT198.
https://doi.org/10.1158/1538-7445.AM2023-CT198
Published: 14 April 2023
View article titled, Abstract CT198: Immunomodulatory effects of the ATR inhibitor ceralasertib in a window of opportunity biomarker trial in patients with head and neck squamous cell carcinoma
Journal Articles

Abstract 4338: Response to neoadjuvant targeted therapy in operable head and neck cancer confers survival benefit

Marco Antonio Mascarella, Tolani Olonisakin, Purva Rumde, Varun Vendra, Melonie Nance, Seungwon Kim, Mark Kubik, Shaum Sridharan, Robert Ferris, Moon Fenton, Daniel Clayburgh, James Ohr, Malabika Sen, Sonali Joyce, James Herman, Jennifer Grandis, Dan Zandberg, Umamaheswar Duvvuri
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4338.
https://doi.org/10.1158/1538-7445.AM2023-4338
Published: 04 April 2023
View article titled, Abstract 4338: Response to neoadjuvant targeted therapy in operable head and neck cancer confers survival benefit
Journal Articles

Editor's Note: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Toni M. Brand, Stefan Hartmann, Neil E. Bhola, Hua Li, Yan Zeng, Rachel A. O'Keefe, Max V. Ranall, Sourav Bandyopadhyay, Margaret Soucheray, Nevan J. Krogan, Carolyn Kemp, Umamaheswar Duvvuri, Theresa LaVallee, Daniel E. Johnson, Michelle A. Ozbun, Julie E. Bauman, Jennifer R. Grandis
Journal: Cancer Research
Cancer Res (2022) 82 (17): 3188.
https://doi.org/10.1158/0008-5472.CAN-22-1307
Published: 02 September 2022
View article titled, Editor's Note: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer
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Journal Articles

Correction: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Toni M. Brand, Stefan Hartmann, Neil E. Bhola, Hua Li, Yan Zeng, Rachel A. O'Keefe, Max V. Ranall, Sourav Bandyopadhyay, Margaret Soucheray, Nevan J. Krogan, Carolyn Kemp, Umamaheswar Duvvuri, Theresa LaVallee, Daniel E. Johnson, Michelle A. Ozbun, Julie E. Bauman, Jennifer R. Grandis
Journal: Cancer Research
Cancer Res (2022) 82 (17): 3187.
https://doi.org/10.1158/0008-5472.CAN-22-1308
Published: 02 September 2022
View article titled, Correction: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer
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Journal Articles

Abstract CT135: A pre-surgical window of opportunity study to investigate the biomarker effects of DNA damage response (DDR) agents in patients (pts) with head and neck squamous cell carcinoma (HNSCC)

Umamaheswar Duvvuri, Emma Dean, Paul Frewer, Alienor Berges, S. Y. Cheung, Christine Stephens, Musaddiq Khan, Simon J. Hollingsworth, Andrew J. Pierce
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT135.
https://doi.org/10.1158/1538-7445.AM2018-CT135
Published: 01 July 2018
View article titled, Abstract CT135: A pre-surgical window of opportunity study to investigate the biomarker effects of DNA damage response (DDR) agents in patients (pts) with head and neck squamous cell carcinoma (HNSCC)
Journal Articles

Abstract CT058: Molecular and clinical activity of CDX-3379, an anti-ErbB3 monoclonal antibody, in head and neck squamous cell carcinoma: A preoperative "window of opportunity" study

Umamaheswar Duvvuri, Jonathan George, Seungwon Kim, Diego Alvarado, Veronique Neumeister, Ahmed Chenna, Thomas Hawthorne, Theresa LaVallee, Jennifer R. Grandis, Julie E. Bauman
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT058.
https://doi.org/10.1158/1538-7445.AM2018-CT058
Published: 01 July 2018
View article titled, Abstract CT058: Molecular and clinical activity of CDX-3379, an anti-ErbB3 monoclonal antibody, in head and neck squamous cell carcinoma: A preoperative "window of opportunity" study
Journal Articles

Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Toni M. Brand, Stefan Hartmann, Neil E. Bhola, Hua Li, Yan Zeng, Rachel A. O'Keefe, Max V. Ranall, Sourav Bandyopadhyay, Margaret Soucheray, Nevan J. Krogan, Carolyn Kemp, Umamaheswar Duvvuri, Theresa LaVallee, Daniel E. Johnson, Michelle A. Ozbun, Julie E. Bauman, Jennifer R. Grandis
Journal: Cancer Research
Cancer Res (2018) 78 (9): 2383–2395.
https://doi.org/10.1158/0008-5472.CAN-17-1672
Published: 30 April 2018
View article titled, Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer
Open the PDF for Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2713: The mutational landscape of recurrent and nonrecurrent human papillomavirus-associated head and neck squamous cell carcinoma

Richard A. Harbison, Mark Kubik, Eric Q. Konnick, Seok-Geun Lee, Michael Kao, Michael Mason, Thomas Yu, Chang Xu, Daniel Faden, Colin C. Pritchard, Cristina P. Rodriguez, Chu Chen, Justin Guinney, Umamaheswar Duvvuri, Eduardo Mendez
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2713.
https://doi.org/10.1158/1538-7445.AM2017-2713
Published: 01 July 2017
View article titled, Abstract 2713: The mutational landscape of recurrent and nonrecurrent human papillomavirus-associated head and neck squamous cell carcinoma
Journal Articles

Abstract 2979: Dual targeting of HER3 and PIK3CA has potent anti-tumor effects in pre-clinical models of HNSCC

Nayel Khan, Kara S. Davis, Neal Godse, Carolyn Kemp, Sucheta Kulkarni, Diego Alvarado, Theresa LaVallee, Jennifer R. Grandis, Umamaheswar Duvvuri
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2979.
https://doi.org/10.1158/1538-7445.AM2016-2979
Published: 15 July 2016
View article titled, Abstract 2979: Dual targeting of HER3 and PIK3CA has potent anti-tumor effects in pre-clinical models of HNSCC
Journal Articles

Abstract 1674: HER3 inhibition potentiates anti-tumor effects of PI3K inhibitors in pre-clinical models of HNSCC

Kara S. Davis, Nayel Khan, Carolyn Kemp, Sucheta Kulkarni, Diego Alvarado, Theresa LaVallee, Jennifer R. Grandis, Umamaheswar Duvvuri
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1674.
https://doi.org/10.1158/1538-7445.AM2015-1674
Published: 01 August 2015
View article titled, Abstract 1674: HER3 inhibition potentiates anti-tumor effects of PI3K inhibitors in pre-clinical models of HNSCC
Journal Articles

Abstract 5106: Influence of chloride flux on cell motility in head and neck squamous cell carcinoma

Nayel Khan, Kevin Steehler, Carolyn Kemp, Sucheta Kulkarni, Kara Davis, Umamaheswar Duvvuri
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5106.
https://doi.org/10.1158/1538-7445.AM2015-5106
Published: 01 August 2015
View article titled, Abstract 5106: Influence of chloride flux on cell motility in head and neck squamous cell carcinoma
Journal Articles

TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression

Umamaheswar Duvvuri, Daniel J. Shiwarski, Dong Xiao, Carol Bertrand, Xin Huang, Robert S. Edinger, Jason R. Rock, Brian D. Harfe, Brian J. Henson, Karl Kunzelmann, Rainer Schreiber, Raja S. Seethala, Ann Marie Egloff, Xing Chen, Vivian W. Lui, Jennifer R. Grandis, Susanne M. Gollin
Journal: Cancer Research
Cancer Res (2012) 72 (13): 3270–3281.
https://doi.org/10.1158/0008-5472.CAN-12-0475-T
Published: 01 July 2012
View article titled, TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression
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Includes: Supplementary data
Journal Articles

Abstract LB-220: TMEM16A, a novel calcium-activated chloride channel, modulates tumor proliferation via MAPK and Cyclin-D1 signaling

Daniel Shiwarski, Carol Bertrand, Ann Marie Egloff, Xin Huang, Raja Seethala, Jennifer Grandis, Susanne Gollin, Umamaheswar Duvvuri
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-220.
https://doi.org/10.1158/1538-7445.AM2011-LB-220
Published: 15 April 2011
View article titled, Abstract LB-220: TMEM16A, a novel calcium-activated chloride channel, modulates tumor proliferation via MAPK and Cyclin-D1 signaling
Journal Articles

Quantitative T1ρ Magnetic Resonance Imaging of RIF-1 Tumors in Vivo : Detection of Early Response to Cyclophosphamide Therapy

Umamaheswar Duvvuri, Harish Poptani, Michael Feldman, Lydie Nadal-Desbarats, Michael S. Gee, William M. F. Lee, Ravinder Reddy, John S. Leigh, Jerry D. Glickson
Journal: Cancer Research
Cancer Res (2001) 61 (21): 7747–7753.
Published: 01 November 2001
View article titled, Quantitative T<sub>1ρ</sub> Magnetic Resonance Imaging of RIF-1 Tumors <em>in Vivo</em> : <subtitle>Detection of Early Response to Cyclophosphamide Therapy</subtitle>
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