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Abstract LB475: Capture the early benign-to-malignant transition of colon cancer in the mouse

Cancer Res (2025) 85 (8_Supplement_2): LB475.

https://doi.org/10.1158/1538-7445.AM2025-LB475

Published: 25 April 2025

View articletitled, Abstract LB475: Capture the early benign-to-malignant transition of colon cancer in the mouse

Journal Articles

Abstract PR016: Early changes to the colon tumor microenvironment during benign-to- malignant transition

Peter M.K. Westcott, Yihan Qin, Daniel Zhang, Nikita Persaud, Zakeria Aminzada, Nischal Bhandari, Colin McLaughlin, William Rideout, III, Santiago Naranjo, Song Han, Rodrigo Romero, Claire Regan, Jonathan Preall, Semir Beyaz, Tyler Jacks, Zhen Zhao, Sepideh Gholami

Cancer Res (2024) 84 (22_Supplement): PR016.

https://doi.org/10.1158/1538-7445.TUMBODY-PR016

Published: 17 November 2024

View articletitled, Abstract PR016: Early changes to the colon tumor microenvironment during benign-to- malignant transition

Journal Articles

Abstract PR-07: Discovery and therapeutic potential of novel cryptic peptides in pancreatic cancer

Cancer Res (2024) 84 (17_Supplement_2): PR-07.

https://doi.org/10.1158/1538-7445.PANCREATIC24-PR-07

Published: 15 September 2024

View articletitled, Abstract PR-07: Discovery and therapeutic potential of novel cryptic peptides in pancreatic cancer

Journal Articles

Abstract A038: Non-canonical MHC class I-associated antigens in pancreatic cancer

Cancer Res (2024) 84 (2_Supplement): A038.

https://doi.org/10.1158/1538-7445.PANCA2023-A038

Published: 16 January 2024

View articletitled, Abstract A038: Non-canonical MHC class I-associated antigens in pancreatic cancer

Journal Articles

Abstract B106: Spatially-constrained optimal transport interaction analysis reveals therapy-associated remodeling in the pancreatic cancer microenvironment

Cancer Res (2024) 84 (2_Supplement): B106.

https://doi.org/10.1158/1538-7445.PANCA2023-B106

Published: 16 January 2024

View articletitled, Abstract B106: Spatially-constrained optimal transport interaction analysis reveals therapy-associated remodeling in the pancreatic cancer microenvironment

Journal Articles

Abstract 2513: Distinct cancer-intrinsic mechanisms mediate nerve recruitment/outgrowth versus perineural invasion

William L. Hwang, Jennifer Su, Carina Shiau, Peter L. Wang, Jimmy A. Guo, Nicole A. Lester, Jaimie L. Barth, Hannah I. Hoffman, Prajan Divakar, Jason W. Reeves, Eric Miller, Joseph M. Beechem, Andrew J. Aguirre, Lei Zheng, David T. Ting, Mari Mino-Kenudson, Tyler Jacks

Cancer Res (2023) 83 (7_Supplement): 2513.

https://doi.org/10.1158/1538-7445.AM2023-2513

Published: 04 April 2023

View articletitled, Abstract 2513: Distinct cancer-intrinsic mechanisms mediate nerve recruitment/outgrowth versus perineural invasion

Journal Articles

Abstract 5877: Intratumoral lymphocyte networks harbor TCF1+ PD1+ progenitor CD8 T cells in lung cancer

Megan L. Burger, Giorgio Gaglia, Claire C. Ritch, Danae Rammos, Yang Dai, Grace E. Crossland, Sara Z. Tavana, Simon Warchol, Alex M. Jaeger, Santiago Naranjo, Shannon Coy, Ajit J. Nirmal, Robert Krueger, Jia-Ren Lin, Hanspeter Pfister, Peter K. Sorger, Tyler Jacks, Sandro Santagata

Cancer Res (2023) 83 (7_Supplement): 5877.

https://doi.org/10.1158/1538-7445.AM2023-5877

Published: 04 April 2023

View articletitled, Abstract 5877: Intratumoral lymphocyte networks harbor TCF1+ PD1+ progenitor CD8 T cells in lung cancer

Journal Articles

Abstract 5775: GLIS3 drives a neural-like malignant state enriched after neoadjuvant treatment in pancreatic cancer

Cancer Res (2023) 83 (7_Supplement): 5775.

https://doi.org/10.1158/1538-7445.AM2023-5775

Published: 04 April 2023

View articletitled, Abstract 5775: GLIS3 drives a neural-like malignant state enriched after neoadjuvant treatment in pancreatic cancer

Journal Articles

Abstract C014: Broadening the repertoire of PDAC-specific targets for immune-based therapy through high-resolution immunopeptidomics

Zackery A. Ely, William A. Freed-Pastor, Zachary J. Kulstad, Jennifer G. Abelin, Eva Verzani, Kevin S. Kapner, Susan Klaeger, Karl R. Clauser, Miles Agus, Alex M. Jaeger, Nimisha B. Pattada, Arjun Bhutkar, Andrew J. Aguirre, Steven A. Carr, Tyler Jacks

Cancer Res (2022) 82 (22_Supplement): C014.

https://doi.org/10.1158/1538-7445.PANCA22-C014

Published: 15 November 2022

View articletitled, Abstract C014: Broadening the repertoire of PDAC-specific targets for immune-based therapy through high-resolution immunopeptidomics

Journal Articles

Abstract A052: Systematic dissection of transcriptional states in pancreatic cancer

Cancer Res (2022) 82 (22_Supplement): A052.

https://doi.org/10.1158/1538-7445.PANCA22-A052

Published: 15 November 2022

View articletitled, Abstract A052: Systematic dissection of transcriptional states in pancreatic cancer

Journal Articles

Abstract C052: Identifying mediators of perineural invasion in pancreatic cancer using spatial transcriptomics

Cancer Res (2022) 82 (22_Supplement): C052.

https://doi.org/10.1158/1538-7445.PANCA22-C052

Published: 15 November 2022

View articletitled, Abstract C052: Identifying mediators of perineural invasion in pancreatic cancer using spatial transcriptomics

Journal Articles

Abstract SY12-04: Multicellular spatial community featuring a novel neuronal-like malignant phenotype is enriched in pancreatic cancer after neoadjuvant chemotherapy and radiotherapy

Cancer Res (2022) 82 (12_Supplement): SY12-04.

https://doi.org/10.1158/1538-7445.AM2022-SY12-04

Published: 15 June 2022

View articletitled, Abstract SY12-04: Multicellular spatial community featuring a novel neuronal-like malignant phenotype is enriched in pancreatic cancer after neoadjuvant chemotherapy and radiotherapy

Journal Articles

Abstract 2194: Rapid interrogation of colon cancer driver genes in vivo using split Cre and CRISPR-Cas9

Daniel Zhang, Peter Westcott, Santiago Naranjo, Haley Hauck, William Rideout, Nate Sacks, Arjun Bhutkar, Justin Patten, Norihiro Goto, Joseph Sedlak, Tyler Jacks

Cancer Res (2022) 82 (12_Supplement): 2194.

https://doi.org/10.1158/1538-7445.AM2022-2194

Published: 15 June 2022

View articletitled, Abstract 2194: Rapid interrogation of colon cancer driver genes in vivo using split Cre and CRISPR-Cas9

Journal Articles

Abstract PR-006: Integrative genomic characterization of therapeutic targets for pancreatic cancer

Cancer Res (2021) 81 (22_Supplement): PR-006.

https://doi.org/10.1158/1538-7445.PANCA21-PR-006

Published: 15 November 2021

View articletitled, Abstract PR-006: Integrative genomic characterization of therapeutic targets for pancreatic cancer

Journal Articles

Abstract PO-063: Functional interrogation of immune escape in neoantigen-expressing pancreatic cancer identifies a critical role for the CD155/TIGIT axis

William Freed-Pastor, Laurens Lambert, Zackery Ely, Nimisha Pattada, Arjun Bhutkar, Alex Jaeger, George Eng, Kim Mercer, William Hwang, Tyler Jacks

Cancer Res (2021) 81 (22_Supplement): PO-063.

https://doi.org/10.1158/1538-7445.PANCA21-PO-063

Published: 15 November 2021

View articletitled, Abstract PO-063: Functional interrogation of immune escape in neoantigen-expressing pancreatic cancer identifies a critical role for the CD155/TIGIT axis

Journal Articles

Abstract 122: Highly multiplexed, spatially-resolved tissue imaging of genetically engineered mouse models of cancer to discover and characterize immune regulators of tumorigenesis

Giorgio Gaglia, Megan Burger, Claire Ritch, Danae Argyropoulou, Yang Dai, Shannon Coy, Jia-Ren Lin, Peter Sorger, Tyler Jacks, Sandro Santagata

Cancer Res (2021) 81 (13_Supplement): 122.

https://doi.org/10.1158/1538-7445.AM2021-122

Published: 01 July 2021

View articletitled, Abstract 122: Highly multiplexed, spatially-resolved tissue imaging of genetically engineered mouse models of cancer to discover and characterize immune regulators of tumorigenesis

Journal Articles

Abstract 94: Multi-compartment reprogramming and spatially-resolved interactions in frozen pancreatic cancer with and without neoadjuvant chemotherapy and radiotherapy at single-cell resolution

Cancer Res (2021) 81 (13_Supplement): 94.

https://doi.org/10.1158/1538-7445.AM2021-94

Published: 01 July 2021

View articletitled, Abstract 94: Multi-compartment reprogramming and spatially-resolved interactions in frozen pancreatic cancer with and without neoadjuvant chemotherapy and radiotherapy at single-cell resolution

Journal Articles

Abstract 2506: Smarca4 inactivation promotes lineage-specific transformation and early metastatic features in the lung

Cancer Res (2021) 81 (13_Supplement): 2506.

https://doi.org/10.1158/1538-7445.AM2021-2506

Published: 01 July 2021

View articletitled, Abstract 2506: Smarca4 inactivation promotes lineage-specific transformation and early metastatic features in the lung

Journal Articles

Abstract 2924: In vivo CRISPR/Cas9 models of microsatellite instable colon cancer reveal recurrent mutations in putative tumor supressor genes

Daniel D. Zhang, Peter M. Westcott, Olivia Smith, Nate Sacks, Haley Hauck, Mary C. Beytagh, Abbey Jin, Tyler Jacks

Cancer Res (2021) 81 (13_Supplement): 2924.

https://doi.org/10.1158/1538-7445.AM2021-2924

Published: 01 July 2021

View articletitled, Abstract 2924: In vivo CRISPR/Cas9 models of microsatellite instable colon cancer reveal recurrent mutations in putative tumor supressor genes

Journal Articles

BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency

Cancer Res (2020) 80 (18): 3841–3854.

https://doi.org/10.1158/0008-5472.CAN-20-1744

Published: 15 September 2020

View articletitled, BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency

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Abstract LB475: Capture the early benign-to-malignant transition of colon cancer in the mouse

Abstract PR016: Early changes to the colon tumor microenvironment during benign-to- malignant transition

Abstract PR-07: Discovery and therapeutic potential of novel cryptic peptides in pancreatic cancer

Abstract A038: Non-canonical MHC class I-associated antigens in pancreatic cancer

Abstract B106: Spatially-constrained optimal transport interaction analysis reveals therapy-associated remodeling in the pancreatic cancer microenvironment

Abstract 2513: Distinct cancer-intrinsic mechanisms mediate nerve recruitment/outgrowth versus perineural invasion

Abstract 5877: Intratumoral lymphocyte networks harbor TCF1+ PD1+ progenitor CD8 T cells in lung cancer

Abstract 5775: GLIS3 drives a neural-like malignant state enriched after neoadjuvant treatment in pancreatic cancer

Abstract C014: Broadening the repertoire of PDAC-specific targets for immune-based therapy through high-resolution immunopeptidomics

Abstract A052: Systematic dissection of transcriptional states in pancreatic cancer

Abstract C052: Identifying mediators of perineural invasion in pancreatic cancer using spatial transcriptomics

Abstract SY12-04: Multicellular spatial community featuring a novel neuronal-like malignant phenotype is enriched in pancreatic cancer after neoadjuvant chemotherapy and radiotherapy

Abstract 2194: Rapid interrogation of colon cancer driver genes in vivo using split Cre and CRISPR-Cas9

Abstract PR-006: Integrative genomic characterization of therapeutic targets for pancreatic cancer

Abstract PO-063: Functional interrogation of immune escape in neoantigen-expressing pancreatic cancer identifies a critical role for the CD155/TIGIT axis

Abstract 122: Highly multiplexed, spatially-resolved tissue imaging of genetically engineered mouse models of cancer to discover and characterize immune regulators of tumorigenesis

Abstract 94: Multi-compartment reprogramming and spatially-resolved interactions in frozen pancreatic cancer with and without neoadjuvant chemotherapy and radiotherapy at single-cell resolution

Abstract 2506: Smarca4 inactivation promotes lineage-specific transformation and early metastatic features in the lung

Abstract 2924: In vivo CRISPR/Cas9 models of microsatellite instable colon cancer reveal recurrent mutations in putative tumor supressor genes

BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency

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