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Turgut Dogruluk
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Journal Articles

Abstract PO5-13-06: Classifying HER2-low breast cancer using a combination of ERBB2 mRNA expression and altered genes

Gargi Basu, Niru Chennagiri, Turgut Dogruluk, David Hall, Jess Hoag, Cynthia Flannery, Snehal Thakkar, Melanie Palomares, Frederick Baehner, Lajos Pusztai
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO5-13-06.
https://doi.org/10.1158/1538-7445.SABCS23-PO5-13-06
Published: 02 May 2024
View article titled, Abstract PO5-13-06: Classifying HER2-low breast cancer using a combination of ERBB2 mRNA expression and altered genes
Journal Articles

Abstract P5-14-12: ESR1-alterations in HR+HER2- breast cancer patients

Gargi Basu, Sameer S. Udhane, Susan Dombrowski, Lenny Hong, Fadel Alyaqoub, Michelle Barbi de Moura, Thiruppavai Chandrasekaran, Turgut Dogruluk, David Driscoll, Aimee Jalkanen, Pawan Noel, Szabolcs Szelinger, Min Wang, David Hall, Jess Hoag, Janine Lobello, Frederick Baehner, Snehal Thakkar, Joyce O’Shaughnessy
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P5-14-12.
https://doi.org/10.1158/1538-7445.SABCS22-P5-14-12
Published: 01 March 2023
View article titled, Abstract P5-14-12: ESR1-alterations in HR+HER2- breast cancer patients
Journal Articles

Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer

Hengyu Lu, Nicole Villafane, Turgut Dogruluk, Caitlin L. Grzeskowiak, Kathleen Kong, Yiu Huen Tsang, Oksana Zagorodna, Angeliki Pantazi, Lixing Yang, Nicholas J. Neill, Young Won Kim, Chad J. Creighton, Roel G. Verhaak, Gordon B. Mills, Peter J. Park, Raju Kucherlapati, Kenneth L. Scott
Journal: Cancer Research
Cancer Res (2017) 77 (13): 3502–3512.
https://doi.org/10.1158/0008-5472.CAN-16-2745
Published: 02 July 2017
View article titled, Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer
Open the PDF for Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer in another window
Includes: Supplementary data
Journal Articles

Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations

Turgut Dogruluk, Yiu Huen Tsang, Maribel Espitia, Fengju Chen, Tenghui Chen, Zechen Chong, Vivek Appadurai, Armel Dogruluk, Agna Karina Eterovic, Penelope E. Bonnen, Chad J. Creighton, Ken Chen, Gordon B. Mills, Kenneth L. Scott
Journal: Cancer Research
Cancer Res (2015) 75 (24): 5341–5354.
https://doi.org/10.1158/0008-5472.CAN-15-1654
Published: 14 December 2015
View article titled, Identification of Variant-Specific Functions of <em>PIK3CA</em> by Rapid Phenotyping of Rare Mutations
Open the PDF for Identification of Variant-Specific Functions of <em>PIK3CA</em> by Rapid Phenotyping of Rare Mutations in another window
Includes: Supplementary data
Journal Articles

Abstract PR06: Functional prioritization of rare gene aberration drivers of cancer

Kenneth Scott, Yiu Huen Tsang, Turgut Dogruluk, Philip Tedeschi, Joseph Bertino, Gordon Mills
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_1): PR06.
https://doi.org/10.1158/1538-7445.TRANSCAGEN-PR06
Published: 15 November 2015
View article titled, Abstract PR06: Functional prioritization of rare gene aberration drivers of cancer
Journal Articles

Abstract 1099: High-throughput engineering and functional annotation of cancer fusion genes

Hengyu Lu, Angeliki Pantazi, Turgut Dogruluk, Armel Dogruluk, Chad Creighton, Gordon B. Mills, Raju Kucherlapati, Kenneth L. Scott
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1099.
https://doi.org/10.1158/1538-7445.AM2015-1099
Published: 01 August 2015
View article titled, Abstract 1099: High-throughput engineering and functional annotation of cancer fusion genes
Journal Articles

Abstract B106: Personalized functional screens for gene drivers of pancreatic cancer

Yiu Huen Tsang, Turgut Dogruluk, Hengyu Lu, Rosalba Minelli, Nikitha Nair, Marie-Claude Gingras, Agda Karina Eterovic, Gordon Mills, Kenneth Scott
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): B106.
https://doi.org/10.1158/1538-7445.PANCA2014-B106
Published: 30 June 2015
View article titled, Abstract B106: Personalized functional screens for gene drivers of pancreatic cancer
Journal Articles

Abstract C10: High-throughput functional annotation of somatic driver aberrations in cancer

Turgut Dogruluk, Armel Dogruluk, Yiu-Huen Tsang, Nikitha Nair, Rosalba Minelli, Ping Wu, Kenneth L. Scott
Journal: Cancer Research
Cancer Res (2013) 73 (19_Supplement): C10.
https://doi.org/10.1158/1538-7445.FBCR13-C10
Published: 15 May 2014
View article titled, Abstract C10: High-throughput functional annotation of somatic driver aberrations in cancer
Journal Articles

Abstract B17: A prioritization pipeline for the identification of somatic driver aberrations in pancreatic cancer.

Turgut Dogruluk, Armel Gifford, Marie-Calude Gingras, Kenneth L. Scott
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): B17.
https://doi.org/10.1158/1538-7445.PANCA2012-B17
Published: 03 April 2014
View article titled, Abstract B17: A prioritization pipeline for the identification of somatic driver aberrations in pancreatic cancer.
Journal Articles

Abstract 3881: HOXA1 drives melanoma tumor growth and metastasis and elicits an invasion gene expression signature that prognosticates clinical outcome.

Joanna Wardwell-Ozgo, Turgut Dogruluk, Armel Gifford, Yiqun zhang, Remco van Doorn, Chad Creighton, Kenneth Scott
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3881.
https://doi.org/10.1158/1538-7445.AM2013-3881
Published: 15 April 2013
View article titled, Abstract 3881: HOXA1 drives melanoma tumor growth and metastasis and elicits an invasion gene expression signature that prognosticates clinical outcome.
Journal Articles

Abstract 1115: Functionally prioritizing somatic driver aberrations in cancer.

Turgut Dogruluk, Yiu-Huen Tsang, Ping Wu, Nikitha Nair, Armel Gifford, Penelope Bonnen, Jianhua Zhang, Kenneth L. Scott
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1115.
https://doi.org/10.1158/1538-7445.AM2013-1115
Published: 15 April 2013
View article titled, Abstract 1115: Functionally prioritizing somatic driver aberrations in cancer.
Journal Articles

Moesin Is a Glioma Progression Marker That Induces Proliferation and Wnt/β-Catenin Pathway Activation via Interaction with CD44

Xiaoping Zhu, Fabiana C. Morales, Nitin Kumar Agarwal, Turgut Dogruluk, Mihai Gagea, Maria-Magdalena Georgescu
Journal: Cancer Research
Cancer Res (2013) 73 (3): 1142–1155.
https://doi.org/10.1158/0008-5472.CAN-12-1040
Published: 31 January 2013
View article titled, Moesin Is a Glioma Progression Marker That Induces Proliferation and Wnt/β-Catenin Pathway Activation via Interaction with CD44
Open the PDF for Moesin Is a Glioma Progression Marker That Induces Proliferation and Wnt/β-Catenin Pathway Activation via Interaction with CD44 in another window
Includes: Supplementary data