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Trevor J. Pugh
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Journal Articles

Abstract PR-17: Genomic and transcriptomic characterization of pancreatic cancer patients on the PASS-01 trial

Grainne M O'Kane, Gunho Jang, Trevor J Pugh, Julie Wilson, Stephanie Ramotar, Daniel A King, Dan Laheru, Ken H Yu, Kimberly J Perez, Amber Habowski, Erica S Tsang, Robert C Grant, Andrew J Aguirre, Raymond W-J Jang, Craig E Devoe, Eileen M O'Reilly, Anna Dodd, Brian M Wolpin, Xiang Y Ye, Elizabeth M Jaffee, David Tuveson, Steven Gallinger, Jennifer J Knox, Faiyaz Notta
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): PR-17.
https://doi.org/10.1158/1538-7445.PANCREATIC24-PR-17
Published: 15 September 2024
View article titled, Abstract PR-17: Genomic and transcriptomic characterization of pancreatic cancer patients on the PASS-01 trial
Journal Articles

Abstract A037 Changes in T-cell repertoire during high-risk neuroblastoma therapy: A report from the Children’s Oncology Group

Yiyue Jiang, Arash Nabbi, Arnavaz Danesh, Stephanie Pedersen, Jenna Eagles, Arlene Naranjo, Kai Tan, Natalie Collins, Steven G. DuBois, Rochelle Bagatell, Brian D. Crompton, Trevor J. Pugh
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): A037.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-A037
Published: 05 September 2024
View article titled, Abstract A037 Changes in T-cell repertoire during high-risk neuroblastoma therapy: A report from the Children’s Oncology Group
Journal Articles

Abstract 1249: cBioPortal for Cancer Genomics

Tali Mazor, Ino de Bruijn, Rima AlHamad, Calla Chennault, Corey Dubin, Jeremy Easton-Marks, Zhaoyuan Fu, Benjamin Gross, Charles Haynes, David M. Higgins, Jason Hwee, Prasanna K. Jagannathan, Mirella Kalafati, Karthik Kalletla, James Ko, Tim Kuijpers, Sowmiyaa Kumar, Priti Kumari, Ritika Kundra, Bryan Lai, Xiang Li, James Lindsay, Aaron Lisman, Qi-Xuan Lu, Ramyasree Madupuri, Angelica Ochoa, Yusuf Z. Özgül, Oleguer Plantalech, Matthijs N. Pon, Baby A. Satravada, Jessica Singh, Selcuk Onur Sumer, Pim van Nierop, Floris Vleugels, Avery Wang, Manda Wilson, Hongxin Zhang, Gaofei Zhao, Ugur Dogrusoz, Allison Heath, Adam Resnick, Trevor J. Pugh, Chris Sander, Ethan Cerami, Jianjiong Gao, Nikolaus Schultz
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1249.
https://doi.org/10.1158/1538-7445.AM2024-1249
Published: 22 March 2024
View article titled, Abstract 1249: cBioPortal for Cancer Genomics
Journal Articles

Abstract B001: Identification of monoallelic ATM loss-of-function and homologous recombination deficiency (HRD) in high-grade ovarian tumor with prolonged response to camonsertib and low-dose gemcitabine combination therapy

Stephanie Lheureux, Joseph D. Schonhoft, Ian M. Silverman, Julia Yang, Adrienne Johnson, Brooke Grant, Alexander Fortuna, Trevor J. Pugh, Parham Nejad, Bernard Lam, Sahaj Arora, Ashley Adile, Stephenie D. Prokopec, Jeffrey Bruce, Danielle Ulanet, Maria Koehler, Ezra Rosen, Victoria Rimkunas
Journal: Cancer Research
Cancer Res (2024) 84 (1_Supplement): B001.
https://doi.org/10.1158/1538-7445.DNAREPAIR24-B001
Published: 09 January 2024
View article titled, Abstract B001: Identification of monoallelic <em>ATM</em> loss-of-function and homologous recombination deficiency (HRD) in high-grade ovarian tumor with prolonged response to camonsertib and low-dose gemcitabine combination therapy
Journal Articles

Analysis and Visualization of Longitudinal Genomic and Clinical Data from the AACR Project GENIE Biopharma Collaborative in cBioPortal

Ino de Bruijn, Ritika Kundra, Brooke Mastrogiacomo, Thinh Ngoc Tran, Luke Sikina, Tali Mazor, Xiang Li, Angelica Ochoa, Gaofei Zhao, Bryan Lai, Adam Abeshouse, Diana Baiceanu, Ersin Ciftci, Ugur Dogrusoz, Andrew Dufilie, Ziya Erkoc, Elena Garcia Lara, Zhaoyuan Fu, Benjamin Gross, Charles Haynes, Allison Heath, David Higgins, Prasanna Jagannathan, Karthik Kalletla, Priti Kumari, James Lindsay, Aaron Lisman, Bas Leenknegt, Pieter Lukasse, Divya Madela, Ramyasree Madupuri, Pim van Nierop, Oleguer Plantalech, Joyce Quach, Adam C. Resnick, Sander Y.A. Rodenburg, Baby A. Satravada, Fedde Schaeffer, Robert Sheridan, Jessica Singh, Rajat Sirohi, Selcuk Onur Sumer, Sjoerd van Hagen, Avery Wang, Manda Wilson, Hongxin Zhang, Kelsey Zhu, Nicole Rusk, Samantha Brown, Jessica A. Lavery, Katherine S. Panageas, Julia E. Rudolph, Michele L. LeNoue-Newton, Jeremy L. Warner, Xindi Guo, Haley Hunter-Zinck, Thomas V. Yu, Shirin Pilai, Chelsea Nichols, Stuart M. Gardos, John Philip, AACR Project GENIE BPC Core Team, AACR Project GENIE Consortium, Kenneth L. Kehl, Gregory J. Riely, Deborah Schrag, Jocelyn Lee, Michael V. Fiandalo, Shawn M. Sweeney, Trevor J. Pugh, Chris Sander, Ethan Cerami, Jianjiong Gao, Nikolaus Schultz
Journal: Cancer Research
Cancer Res (2023) 83 (23): 3861–3867.
https://doi.org/10.1158/0008-5472.CAN-23-0816
Published: 01 December 2023
View article titled, Analysis and Visualization of Longitudinal Genomic and Clinical Data from the AACR Project GENIE Biopharma Collaborative in cBioPortal
Open the PDF for Analysis and Visualization of Longitudinal Genomic and Clinical Data from the AACR Project GENIE Biopharma Collaborative in cBioPortal in another window
Includes: Supplementary data
Journal Articles

Abstract 4256: cBioPortal for Cancer Genomics

Ino de Bruijn, Tali Mazor, Adam Abeshouse, Diana Baiceanu, Stephanie Carrero, Elena Garcia Lara, Benjamin Gross, David M. Higgins, Prasanna K. Jagannathan, Priti Kumari, Ritika Kundra, Bryan Lai, Xiang Li, James Lindsay, Aaron Lisman, Divya Madala, Ramyasree Madupuri, Angelica Ochoa, Yusuf Ziya Özgül, Oleguer Plantalech, Sander Rodenburg, Baby Anusha Satravada, Robert Sheridan, Lucas Sikina, Jessica Singh, S Onur Sumer, Yichao Sun, Pim van Nierop, Avery Wang, Manda Wilson, Hongxin Zhang, Gaofei Zhao, Sjoerd van Hagen, Ugur Dogrusoz, Allison Heath, Adam Resnick, Trevor J. Pugh, Chris Sander, Ethan Cerami, Jianjiong Gao, Nikolaus Schultz
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4256.
https://doi.org/10.1158/1538-7445.AM2023-4256
Published: 04 April 2023
View article titled, Abstract 4256: cBioPortal for Cancer Genomics
Journal Articles

Abstract 6667: Pan-cancer assessment of tumour and peripheral T-cell receptor repertoire dynamics in patients treated with immune checkpoint inhibitors

Shirin Soleimani, Ben X. Wang, Stephanie Pedersen, Jenna Eagles, Jacob Brick, Marcus O. Butler, Scott V. Bratman, Lillian L. Siu, Pamela S. Ohashi, Trevor J. Pugh
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6667.
https://doi.org/10.1158/1538-7445.AM2023-6667
Published: 04 April 2023
View article titled, Abstract 6667: Pan-cancer assessment of tumour and peripheral T-cell receptor repertoire dynamics in patients treated with immune checkpoint inhibitors
Journal Articles

Abstract 1155: cBioPortal for cancer genomics

Jianjiong Gao, Tali Mazor, Ino de Bruijn, Adam Abeshouse, Diana Baiceanu, Ziya Erkoc, Elena Garcia Lara, Benjamin Gross, David M. Higgins, Prasanna K. Jagannathan, Priti Kumari, Ritika Kundra, Xiang Li, James Lindsay, Aaron Lisman, Divya Madala, Ramyasree Madupuri, Angelica Ochoa, Oleguer Plantalech, Sander Rodenburg, Baby A. Satravada, Robert Sheridan, Lucas Sikina, Jessica Singh, S. Onur Sumer, Yichao Sun, Pim van Nierop, Avery Wang, Manda Wilson, Hongxin Zhang, Gaofei Zhao, Sjoerd van Hagen, Kees van Bochove, Ugur Dogrusoz, Allison Heath, Adam Resnick, Trevor J. Pugh, Chris Sander, Ethan Cerami, Nikolaus Schultz
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1155.
https://doi.org/10.1158/1538-7445.AM2022-1155
Published: 15 June 2022
View article titled, Abstract 1155: cBioPortal for cancer genomics
Journal Articles

Abstract LB098: Vulnerability of MTAP-deleted nasopharyngeal carcinoma to MAT2A inhibition

Yuk Yu Chan, Jeff P. Bruce, Vivian W.Y. Lui, Grace T. Y. Chung, Sai-Wah Tsao, Ka-Fai To, Trevor J. Pugh, Kwok-Wai Lo
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB098.
https://doi.org/10.1158/1538-7445.AM2021-LB098
Published: 01 July 2021
View article titled, Abstract LB098: Vulnerability of <em>MTAP</em>-deleted nasopharyngeal carcinoma to MAT2A inhibition
Journal Articles

Abstract 207: The cBioPortal for Cancer Genomics

Jianjiong Gao, Tali Mazor, Ino de Bruijn, Adam Abeshouse, Diana Baiceanu, Ziya Erkoc, Benjamin Gross, David Higgins, Prasanna K. Jagannathan, Karthik Kalletla, Priti Kumari, Ritika Kundra, Xiang Li, James Lindsay, Aaron Lisman, Pieter Lukasse, Divya Madala, Ramyasree Madupuri, Angelica Ochoa, Oleguer Plantalech, Joyce Quach, Sander Rodenburg, Anusha Satravada, Fedde Schaeffer, Robert Sheridan, Lucas Sikina, S. Onur Sumer, Yichao Sun, Paul van Dijk, Pim van Nierop, Avery Wang, Manda Wilson, Hongxin Zhang, Gaofei Zhao, Sjoerd van Hagen, Kees van Bochove, Ugur Dogrusoz, Allison Heath, Adam Resnick, Trevor J. Pugh, Chris Sander, Ethan Cerami, Nikolaus Schultz
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 207.
https://doi.org/10.1158/1538-7445.AM2021-207
Published: 01 July 2021
View article titled, Abstract 207: The cBioPortal for Cancer Genomics
Journal Articles

Brain Tumor Stem Cell Dependence on Glutaminase Reveals a Metabolic Vulnerability through the Amino Acid Deprivation Response Pathway

Ian J. Restall, Orsolya Cseh, Laura M. Richards, Trevor J. Pugh, H. Artee Luchman, Samuel Weiss
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (24): 5478–5490.
https://doi.org/10.1158/0008-5472.CAN-19-3923
Published: 15 December 2020
View article titled, Brain Tumor Stem Cell Dependence on Glutaminase Reveals a Metabolic Vulnerability through the Amino Acid Deprivation Response Pathway
Open the PDF for Brain Tumor Stem Cell Dependence on Glutaminase Reveals a Metabolic Vulnerability through the Amino Acid Deprivation Response Pathway in another window
Includes: Supplementary data
Journal Articles

Abstract 3209: The cBioPortal for Cancer Genomics

Jianjiong Gao, Tali Mazor, Adam Abeshouse, Ino de Bruijn, Benjamin Gross, Karthik Kalletla, Priti Kumari, Ritika Kundra, Xiang Li, James Lindsay, Aaron Lisman, Pieter Lukasse, Ramyasree Madupuri, Angelica Ochoa, Oleguer Plantalech, Sander Rodenburg, Fedde Schaeffer, Robert Sheridan, Lucas Sikina, Jing Su, S. Onur Sumer, Yichao Sun, Paul van Dijk, Sjoerd van Hagen, Pim van Nierop, Avery Wang, Manda Wilson, Hongxin Zhang, Gaofei Zhao, Kelsey Zhu, Kees van Bochove, Ugur Dogrusoz, Allison Heath, Adam Resnick, Trevor J. Pugh, Chris Sander, Ethan Cerami, Nikolaus Schultz
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3209.
https://doi.org/10.1158/1538-7445.AM2020-3209
Published: 15 August 2020
View article titled, Abstract 3209: The cBioPortal for Cancer Genomics
Journal Articles

Abstract 1869: Methylation signatures associated with T790M status in progressive NSCLC

Grainne M. O'Kane, Alberto J. León, Muqdas Shabir, Jennifer H. Law, Penelope A. Bradbury, Geoff Liu, Adrian Sacher, Frances A. Shepherd, Dax Torti, Tracy L. Stockley, Ming Tsao, Trevor J. Pugh, Natasha B. Leighl
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1869.
https://doi.org/10.1158/1538-7445.AM2020-1869
Published: 15 August 2020
View article titled, Abstract 1869: Methylation signatures associated with T790M status in progressive NSCLC
Journal Articles

Abstract PR06: The immunogenomic landscape of pediatric primary solid tumors

Arash Nabbi, Pengbo Sun, Sudhaman Sumedha, Kelsey Zhu, S.Y. Cindy Yang, Joseph N. Paulson, Marcel Kool, Komal Rathi, Karthik Kalletla, Pichai Raman, Yuankun Zhu, Adam C. Resnick, David T.W. Jones, Natalie Jäger, Stefan M. Pfister, Trevor J. Pugh
Journal: Cancer Research
Cancer Res (2020) 80 (14_Supplement): PR06.
https://doi.org/10.1158/1538-7445.PEDCA19-PR06
Published: 15 July 2020
View article titled, Abstract PR06: The immunogenomic landscape of pediatric primary solid tumors
Journal Articles

Abstract 910: The cBioPortal for cancer genomics

Jianjiong Gao, Tali Mazor, Adam Abeshouse, Ersin Ciftci, Ino de Bruijn, Benjamin Gross, Karthik Kalletla, Priti Kumari, Ritika Kundra, James Lindsay, Aaron Lisman, Pieter Lukasse, Ramyasree Madupuri, Angelica Ochoa, Oleguer Plantalech, Pichai Raman, Fedde Schaeffer, Robert Sheridan, Jing Su, S. Onur Sumer, Yichao Sun, Sander Tan, Sjoerd van Hagen, Avery Wang, Manda Wilson, Hongxin Zhang, Gaofei Zhao, Kelsey Zhu, Kees van Bochove, Ugur Dogrusoz, Trevor J. Pugh, Adam Resnick, Chris Sander, Ethan Cerami, Nikolaus Schultz
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 910.
https://doi.org/10.1158/1538-7445.AM2019-910
Published: 01 July 2019
View article titled, Abstract 910: The cBioPortal for cancer genomics
Journal Articles

Abstract 967: Single-cell transcriptomics uncovers clonal heterogeneity linked to drug response and cellular phenotype in adult brain tumor stem cells

Laura M. Richards, Owen Whitley, Florence M. Cavalli, Zhaleh Safikhani, Fiona Coutinho, H. Artee Luchman, Benjamin Haibe-Kains, Samuel Weiss, Peter Dirks, Gary Bader, Trevor J. Pugh
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 967.
https://doi.org/10.1158/1538-7445.AM2019-967
Published: 01 July 2019
View article titled, Abstract 967: Single-cell transcriptomics uncovers clonal heterogeneity linked to drug response and cellular phenotype in adult brain tumor stem cells
Journal Articles

Abstract 2891: Landscape of infiltrating immune repertoire in pediatric solid tumors

Arash Nabbi, Natalie Jäger, Sumedha Sudhaman, Pengbo Sun, S. Y. Cindy Yang, Kelsey Zhu, Marcel Kool, Komal Rathi, Karthik Kalletla, Pichai Raman, Yuankun Zhu, Joseph N. Paulson, David T. Jones, Uri Tabori, Adam C. Resnick, Stefan M. Pfister, Trevor J. Pugh
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2891.
https://doi.org/10.1158/1538-7445.AM2019-2891
Published: 01 July 2019
View article titled, Abstract 2891: Landscape of infiltrating immune repertoire in pediatric solid tumors
Journal Articles

Intratumoral Genetic and Functional Heterogeneity in Pediatric Glioblastoma

Mary Hoffman, Aaron H. Gillmor, Daniel J. Kunz, Michael J. Johnston, Ana Nikolic, Kiran Narta, Mehdi Zarrei, Jennifer King, Katrina Ellestad, Ngoc Ha Dang, Florence M.G. Cavalli, Michelle M. Kushida, Fiona J. Coutinho, Yuankun Zhu, Betty Luu, Yussanne Ma, Andrew J. Mungall, Richard Moore, Marco A. Marra, Michael D. Taylor, Trevor J. Pugh, Peter B. Dirks, Douglas Strother, Lucie Lafay-Cousin, Adam C. Resnick, Stephen Scherer, Donna L. Senger, Benjamin D. Simons, Jennifer A. Chan, A. Sorana Morrissy, Marco Gallo
Journal: Cancer Research
Cancer Res (2019) 79 (9): 2111–2123.
https://doi.org/10.1158/0008-5472.CAN-18-3441
Published: 01 May 2019
View article titled, Intratumoral Genetic and Functional Heterogeneity in Pediatric Glioblastoma
Open the PDF for Intratumoral Genetic and Functional Heterogeneity in Pediatric Glioblastoma in another window
Includes: Supplementary data
Journal Articles

Abstract 1033: Patient-derived xenografts for prognostication and personalized treatment for head and neck squamous cell carcinoma

Christina Karamboulas, Jeffrey P. Bruce, Andrew J. Hope, Jalna Meens, Shao Hui Huang, Jie Su, Fei-Fei Liu, Trevor J. Pugh, Scott V. Bratman, Wei Xu, Laurie E. Ailles
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1033.
https://doi.org/10.1158/1538-7445.AM2018-1033
Published: 01 July 2018
View article titled, Abstract 1033: Patient-derived xenografts for prognostication and personalized treatment for head and neck squamous cell carcinoma
Journal Articles

Abstract 923: The cBioPortal for Cancer Genomics: An intuitive open-source platform for exploration, analysis and visualization of cancer genomics data

Jianjiong Gao, Tali Mazor, Ersin Ciftci, Pichai Raman, Pieter Lukasse, Istemi Bahceci, Alexandros Sigaras, Adam Abeshouse, Ino de Bruijn, Benjamin Gross, Ritika Kundra, Aaron Lisman, Angelica Ochoa, Robert Sheridan, Jing Su, Selcuk O. Sumer, Yichao Sun, Avery Wang, Jiaojiao Wang, Manda Wilson, Hongxin Zhang, Priti Kumari, James Lindsay, Karthik Kalletla, Kelsey Zhu, Oleguer Plantalech, Fedde Schaeffer, Sander Tan, Dionne Zaal, Sjoerd van Hagen, Kees van Bochove, Ugur Dogrusoz, Trevor J. Pugh, Adam Resnick, Chris Sander, Nikolaus Schultz, Ethan Cerami
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 923.
https://doi.org/10.1158/1538-7445.AM2018-923
Published: 01 July 2018
View article titled, Abstract 923: The cBioPortal for Cancer Genomics: An intuitive open-source platform for exploration, analysis and visualization of cancer genomics data