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Toshiyuki Ishiwata
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Journal Articles

Abstract 2449: FGFR4 inhibitor BLU9931 induces cellular senescence in pancreatic ductal adenocarcinoma cell lines promoting sensitivity to senolytic therapy

Norihiko Sasaki, Fujiya Gomi, Hisashi Yoshimura, Masami Yamamoto, Yoko Matsuda, Masaki Michishita, Hitoshi Hatakeyama, Yoichi Kawano, Yoko Itakura, Masashi Toyoda, Murray Korc, Toshiyuki Ishiwata
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2449.
https://doi.org/10.1158/1538-7445.AM2021-2449
Published: 01 July 2021
View article titled, Abstract 2449: FGFR4 inhibitor BLU9931 induces cellular senescence in pancreatic ductal adenocarcinoma cell lines promoting sensitivity to senolytic therapy
Journal Articles

Abstract 6015: A newly established neuroendocrine carcinoma cell line from a human ascending colon tumor shows high proliferation and CD133 expression in spherical cancer stem cell-like formation

Seiichi Shinji, Norihiko Sasaki, Takeshi Yamada, Michihiro Koizumi, Ryo Ohta, Akihisa Matsuda, Goro Takahashi, Masahiro Hotta, Takuma Iwai, Keisuke Hara, Kohki Takeda, Koji Ueda, Sho Kuriyama, Toshiyuki Ishiwata, Hiroshi Yoshida
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6015.
https://doi.org/10.1158/1538-7445.AM2020-6015
Published: 15 August 2020
View article titled, Abstract 6015: A newly established neuroendocrine carcinoma cell line from a human ascending colon tumor shows high proliferation and CD133 expression in spherical cancer stem cell-like formation
Journal Articles

Abstract 135: Increased expression of ganglioside GM2 correlates with aggressiveness of human pancreatic ductal adenocarcinoma

Norihiko Sasaki, Kenichi Hirabayashi, Masaki Michishita, Kimimasa Takahashi, Fumio Hasegawa, Fujiya Gomi, Yoko Itakura, Naoya Nakamura, Masashi Toyoda, Toshiyuki Ishiwata
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 135.
https://doi.org/10.1158/1538-7445.AM2020-135
Published: 15 August 2020
View article titled, Abstract 135: Increased expression of ganglioside GM2 correlates with aggressiveness of human pancreatic ductal adenocarcinoma
Journal Articles

Abstract 3568: Metastasis-promoting role of H19 long non-coding RNA in pancreatic cancer cells

Norihiko Sasaki, Masashi Toyoda, Hisashi Yoshimura, Yoko Matsuda, Tomio Arai, Yoko Itakura, Fujiya Gomi, Junko Aida, Toshiyuki Ishiwata
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3568.
https://doi.org/10.1158/1538-7445.AM2019-3568
Published: 01 July 2019
View article titled, Abstract 3568: Metastasis-promoting role of <em>H19</em> long non-coding RNA in pancreatic cancer cells
Journal Articles

Abstract 3057: ABCG2-positive cells derived from ABCG2-negative pancreatic cancer cells in 3D-culture conditions show high stemness and anti-cancer drug resistance

Norihiko Sasaki, Fumio Hasegawa, Masaki Michishita, Yoko Matsuda, Tomio Arai, Naoshi Ishikawa, Yoko Itakura, Junko Aida, Kaiyo Takubo, Masashi Toyoda, Toshiyuki Ishiwata
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3057.
https://doi.org/10.1158/1538-7445.AM2018-3057
Published: 01 July 2018
View article titled, Abstract 3057: ABCG2-positive cells derived from ABCG2-negative pancreatic cancer cells in 3D-culture conditions show high stemness and anti-cancer drug resistance
Journal Articles

Abstract 3403: Telomere shortening in pancreatic cancer is correlated to KRAS mutation

Yoko Matsuda, Naotaka Izumiyama, Mutsunori Fujiwara, Naoshi Ishikawa, Junko Aida, Kaiyo Takubo, Toshiyuki Ishiwata, Tomio Arai
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3403.
https://doi.org/10.1158/1538-7445.AM2017-3403
Published: 01 July 2017
View article titled, Abstract 3403: Telomere shortening in pancreatic cancer is correlated to KRAS mutation
Journal Articles

Abstract 3484: A long non-coding RNA, H19, as a novel therapeutic target for pancreatic cancer metastasis

Toshiyuki Ishiwata, Hisashi Yoshimura, Yoko Matsuda, Naoshi Ishikawa, Kaiyo Takubo, Tomio Arai, Junko Aida
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3484.
https://doi.org/10.1158/1538-7445.AM2017-3484
Published: 01 July 2017
View article titled, Abstract 3484: A long non-coding RNA, H19, as a novel therapeutic target for pancreatic cancer metastasis
Journal Articles

Abstract 1157: Single nucleotide polymorphisms in ARHGAP17 are associated with pancreatic intraepithelial neoplasia in 2401 autopsied elderly patients

Yoko Matsuda, Masashi Tanaka, Atsuko Seki, Keisuke Nonaka, Makoto Nishimura, Toshiyuki Ishiwata, Hisashi Yoshimura, Kaiyo Takubo, Tomio Arai
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1157.
https://doi.org/10.1158/1538-7445.AM2016-1157
Published: 15 July 2016
View article titled, Abstract 1157: Single nucleotide polymorphisms in ARHGAP17 are associated with pancreatic intraepithelial neoplasia in 2401 autopsied elderly patients
Journal Articles

Abstract 4577: Fibroblast growth factor receptor-4 (FGFR-4) as a novel therapeutic target for pancreatic cancer

Toshiyuki Ishiwata, Hisashi Yoshimura, Yoko Matsuda, Shunji Ishiwata
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4577.
https://doi.org/10.1158/1538-7445.AM2016-4577
Published: 15 July 2016
View article titled, Abstract 4577: Fibroblast growth factor receptor-4 (FGFR-4) as a novel therapeutic target for pancreatic cancer
Journal Articles

Abstract 3426: Occult and clinical pancreatic cancers in elderly patients

Yoko Matsuda, Akemi Suzuki, Yuri Hamashima, Hideki Hamayasu, Hisashi Yoshimura, Toshiyuki Ishiwata, Tomio Arai
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3426.
https://doi.org/10.1158/1538-7445.AM2015-3426
Published: 01 August 2015
View article titled, Abstract 3426: Occult and clinical pancreatic cancers in elderly patients
Journal Articles

Abstract 1415: Telomere shortening in centroacinar-acinar region of the pancreas: relationships with aging, cancers and tissue stem cells

Yoko Matsuda, Naotaka Izumiyama-Shimomura, Toshiyuki Ishiwata, Mutsunori Fujiwara, Ken-ichiro Tomita, Naoki Hiraishi, Hideki Hamayasu, Ken-ichi Nakamura, Naoshi Ishikawa, Steven Poon, Junko Aida, Kaiyo Takubo, Tomio Arai
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1415.
https://doi.org/10.1158/1538-7445.AM2015-1415
Published: 01 August 2015
View article titled, Abstract 1415: Telomere shortening in centroacinar-acinar region of the pancreas: relationships with aging, cancers and tissue stem cells
Journal Articles

Abstract 5203: Long non-coding RNA H19 as a novel therapeutic target for pancreatic cancer

Hisashi Yoshimura, Yoko Matsuda, Taeko Suzuki, Zenya Naito, Toshiyuki Ishiwata
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5203.
https://doi.org/10.1158/1538-7445.AM2014-5203
Published: 01 October 2014
View article titled, Abstract 5203: Long non-coding RNA H19 as a novel therapeutic target for pancreatic cancer
Journal Articles

Abstract 4062: Nestin regulates proliferation, migration, invasion and stemness of lung adenocarcinoma

Kosuke Narita, Yoko Matsuda, Masahiro Seike, Zenya Naito, Akihiko Gemma, Toshiyuki Ishiwata
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4062.
https://doi.org/10.1158/1538-7445.AM2014-4062
Published: 01 October 2014
View article titled, Abstract 4062: Nestin regulates proliferation, migration, invasion and stemness of lung adenocarcinoma
Journal Articles

Abstract 3892: Inhibitory effects and regulatory mechanism of nestin in pancreatic cancer

Yoko Matsuda, Toshiyuki Ishiwata, Hisashi Yoshimura, Satoshi Yamashita, Toshikazu Ushijima, Kaiyo Takubo, Tomio Arai
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3892.
https://doi.org/10.1158/1538-7445.AM2014-3892
Published: 01 October 2014
View article titled, Abstract 3892: Inhibitory effects and regulatory mechanism of nestin in pancreatic cancer
Journal Articles

Abstract 249: Inhibition of nestin using siRNA as a novel therapeutic option for pancreatic cancer.

Toshiyuki Ishiwata, Hisashi Yoshimura, Taeko Suzuki, Yuji Yanagisawa, Yoko Kawamoto, Kiyoko Kawahara, Zenya Naito, Murray Korc, Yoko Matsuda
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 249.
https://doi.org/10.1158/1538-7445.AM2013-249
Published: 15 April 2013
View article titled, Abstract 249: Inhibition of nestin using siRNA as a novel therapeutic option for pancreatic cancer.
Journal Articles

Abstract 3750: Inhibition of phosphorylation of nestin decrease pancreatic cancer cell growth.

Yoko Matsuda, Hisashi Yoshimura, Taeko Suzuki, Zenya Naito, Kiyoko Kawahara, Yuji Yanagisawa, Yoko Kawamoto, Toshiyuki Ishiwata
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3750.
https://doi.org/10.1158/1538-7445.AM2013-3750
Published: 15 April 2013
View article titled, Abstract 3750: Inhibition of phosphorylation of nestin decrease pancreatic cancer cell growth.
Journal Articles

Abstract 2412: Epithelial splicing regulatory protein 1 modulates cell growth, migration, and invasion of human pancreatic ductal adenocarcinoma

Junji Ueda, Yoko Matsuda, Kazuya Yamahatsu, Eiji Uchida, Zenya Naito, Toshiyuki Ishiwata
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2412.
https://doi.org/10.1158/1538-7445.AM2012-2412
Published: 15 April 2012
View article titled, Abstract 2412: Epithelial splicing regulatory protein 1 modulates cell growth, migration, and invasion of human pancreatic ductal adenocarcinoma
Journal Articles

Abstract 3316: The stem cell marker nestin inhibits growth and invasion of malignant melanoma

Michiko Akiyama, Yoko Matsuda, Masahito Hagio, Kiyoko Kawahara, Taeko Suzuki, Toshiyuki Ishiwata, Seiji Kawana, Zenya Naito
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3316.
https://doi.org/10.1158/1538-7445.AM2012-3316
Published: 15 April 2012
View article titled, Abstract 3316: The stem cell marker nestin inhibits growth and invasion of malignant melanoma
Journal Articles

Abstract 414: Role of stem cell marker, nestin in human uterine cervical intraepithelial neoplasia and cervical cancer

Atsuki Sato, Toshiyuki Ishiwata, Tetsushi Yamamoto, Yoko Matsuda, Hirobumi Asakura, Toshiyuki Takeshita, Zenya Naito
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 414.
https://doi.org/10.1158/1538-7445.AM2012-414
Published: 15 April 2012
View article titled, Abstract 414: Role of stem cell marker, nestin in human uterine cervical intraepithelial neoplasia and cervical cancer
Journal Articles

Abstract 412: Expression of cancer stem cell markers in pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias

Shoko Kure, Yoko Matsuda, Masahito Hagio, Taeko Suzuki, Junji Ueda, Kazuya Yamahatsu, Tetsushi Yamamoto, Zenya Naito, Toshiyuki Ishiwata
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 412.
https://doi.org/10.1158/1538-7445.AM2012-412
Published: 15 April 2012
View article titled, Abstract 412: Expression of cancer stem cell markers in pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias