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Journal Articles

Abstract 1079: Distinct DNA methylation targets by aging and chronic inflammation

Satoshi Yamashita, Sohachi Nanjo, Emil Rehnberg, Naoko Iida, Hideyuki Takeshima, Takayuki Ando, Takao Maekita, Toshiro Sugiyama, Toshikazu Ushijima

Cancer Res (2020) 80 (16_Supplement): 1079.

DOI: https://doi.org/10.1158/1538-7445.AM2020-1079

Published: 15 August 2020

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Journal Articles

Abstract 3056: Development of an integrated CRISPR interference system targeting ΔNp63 to treat lung and esophageal squamous cell carcinoma

Masakazu Yoshida, Etsuko Yokota, Tetsushi Sakuma, Nagio Takigawa, Toshikazu Ushijima, Takashi Yamamoto, Yoshio Naomoto, Takuya Fukazawa, Tomoki Yamatsuji

Cancer Res (2019) 79 (13_Supplement): 3056.

DOI: https://doi.org/10.1158/1538-7445.AM2019-3056

Published: 01 July 2019

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Journal Articles

Abstract 819: DNA methylation genome-wide analysis in remnant gastric cancer

Tomoaki Ito, Kiichi Sugimoto, Hajime Orita, Masahiro Maeda, Hiroshi Moro, Toshikazu Ushijima, Hitoshi Katai, Ryo Wada, Kazuhiro Sakamoto, Koichi Sato, Malcolm V. Brock

Cancer Res (2019) 79 (13_Supplement): 819.

DOI: https://doi.org/10.1158/1538-7445.AM2019-819

Published: 01 July 2019

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Journal Articles

Abstract 838: Epigenetic reprogramming of different cancer-related pathways at the single cell level after low-dose DNA demethylation therapy

Hideyuki Takeshima, Yukie Yoda, Naoko Watanabe, Mika Wakabayashi, Toshikazu Ushijima

Cancer Res (2019) 79 (13_Supplement): 838.

DOI: https://doi.org/10.1158/1538-7445.AM2019-838

Published: 01 July 2019

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Journal Articles

Abstract 843: Epigenomic disruption of adipogenic regulators in dedifferentiated liposarcoma

Hironori Takamatsu, Naoko Hattori, Naofumi Asano, Naoko Iida, Akihiko Yoshida, Eisuke Kobayashi, Robert Nakayama, Morio Matsumoto, Masaya Nakamura, Akira Kawai, Toshikazu Ushijima

Cancer Res (2019) 79 (13_Supplement): 843.

DOI: https://doi.org/10.1158/1538-7445.AM2019-843

Published: 01 July 2019

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Journal Articles

Abstract 5340: The methylation burden is determined by the duration of exposure to carcinogenic factors

Harumi Yamada, Hideyuki Takeshima, Tohru Niwa, Takeshi Toyoda, Satoshi Yamashita, Toshikazu Ushijima

Cancer Res (2018) 78 (13_Supplement): 5340.

DOI: https://doi.org/10.1158/1538-7445.AM2018-5340

Published: 01 July 2018

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Journal Articles

Abstract 5331: Repression of TET genes and enhancement of DNA methyltransferase activity are critical for induction of aberrant DNA methylation

Hideyuki Takeshima, Tohru Niwa, Harumi Yamada, Satoshi Yamashita, Mika Wakabayashi, Toshikazu Ushijima

Cancer Res (2018) 78 (13_Supplement): 5331.

DOI: https://doi.org/10.1158/1538-7445.AM2018-5331

Published: 01 July 2018

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Journal Articles

PRC2-Mediated Transcriptomic Alterations at the Embryonic Stage Govern Tumorigenesis and Clinical Outcome in MYCN-Driven Neuroblastoma

Shoma Tsubota, Satoshi Kishida, Teppei Shimamura, Miki Ohira, Satoshi Yamashita, Dongliang Cao, Shinichi Kiyonari, Toshikazu Ushijima, Kenji Kadomatsu

Cancer Res (2017) 77 (19): 5259–5271.

DOI: https://doi.org/10.1158/0008-5472.CAN-16-3144

Published: 01 October 2017

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Includes: Supplementary data

Journal Articles

Abstract 4260: Increased mutation burden in normal-appearing lung tissues with high cancer risk

Emi Kubo, Hideyuki Takeshima, Noriko Motoi, Toshikazu Ushijima

Cancer Res (2017) 77 (13_Supplement): 4260.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4260

Published: 01 July 2017

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Journal Articles

Abstract 921: Cdyl2 is a chromodomain protein involved in the maintenance of pluripotency of stem cells

Naoko Hattori, Kana Kimura, Jumpei Taguchi, Toshio Imai, Yasuhiro Yamada, Toshikazu Ushijima

Cancer Res (2017) 77 (13_Supplement): 921.

DOI: https://doi.org/10.1158/1538-7445.AM2017-921

Published: 01 July 2017

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Journal Articles

Abstract LB-092: High impact of methylation accumulation on cancer risk: 5-year follow-up of a multicenter prospective cohort study

Masahiro Maeda, Takeshi Nakajima, Ichiro Oda, Taichi Shimazu, Nobutake Yamamichi, Takao Maekita, Kiyoshi Asada, Chizu Yokoi, Takayuki Ando, Takeichi Yoshida, Sohachi Nanjo, Mitsuhiro Fujishiro, Takuji Gotoda, Masao Ichinose, Toshikazu Ushijima

Cancer Res (2017) 77 (13_Supplement): LB-092.

DOI: https://doi.org/10.1158/1538-7445.AM2017-LB-092

Published: 01 July 2017

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Journal Articles

The Moment that KRAS Mutation Started to Evolve into Precision Medicine in Metastatic Colorectal Cancer

Toshikazu Ushijima, Takayuki Yoshino

Cancer Res (2016) 76 (22): 6443–6444.

DOI: https://doi.org/10.1158/0008-5472.CAN-16-2867

Published: 14 November 2016

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Journal Articles

Abstract LB-245: Preclinical study of epigenetic drug-based differentiation therapy for neuroblastoma

Naoko Hattori, Akiko Mori, Kana Kimura, Emi Kubo, Kiyoshi Asada, Hiroshi Kawamoto, Toshikazu Ushijima

Cancer Res (2016) 76 (14_Supplement): LB-245.

DOI: https://doi.org/10.1158/1538-7445.AM2016-LB-245

Published: 15 July 2016

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Journal Articles

Abstract 4460: Precision cancer risk diagnosis by accumulation of epigenetic alterations

Toshikazu Ushijima, Kiyoshi Asada, Masahiro Maeda, Takeshi Nakajima, Taichi Shimazu

Cancer Res (2016) 76 (14_Supplement): 4460.

DOI: https://doi.org/10.1158/1538-7445.AM2016-4460

Published: 15 July 2016

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Journal Articles

Abstract 1048: Chromatin remodelers are frequently disrupted by epigenetic and genetic alterations at an early stage of carcinogenesis

Hideyuki Takeshima, Tohru Niwa, Takamasa Takahashi, Takayuki Ando, Hirokazu Taniguchi, Hitoshi Katai, Toshiro Sugiyama, Toshikazu Ushijima

Cancer Res (2015) 75 (15_Supplement): 1048.

DOI: https://doi.org/10.1158/1538-7445.AM2015-1048

Published: 01 August 2015

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Journal Articles

Abstract LB-157: Demonstration of the usefulness of an epigenetic cancer risk marker by a multicenter prospective cohort study

Masahiro Maeda, Kiyoshi Asada, Takeshi Nakajima, Taichi Shimazu, Nobutake Yamamichi, Takao Maekita, Chizu Yokoi, Ichiro Oda, Takayuki Ando, Takeichi Yoshida, Sohachi Nanjo, Mitsuhiro Fujishiro, Takuji Gotoda, Masao Ichinose, Toshikazu Ushijima

Cancer Res (2015) 75 (15_Supplement): LB-157.

DOI: https://doi.org/10.1158/1538-7445.AM2015-LB-157

Published: 01 August 2015

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Journal Articles

Abstract 2314: The combination of DNA methylation and H3K27me3 is a cancer-specific dual epigenetic modification

Hideyuki Takeshima, Mika Wakabayashi, Naoko Hattori, Satoshi Yamashita, Toshikazu Ushijima

Cancer Res (2014) 74 (19_Supplement): 2314.

DOI: https://doi.org/10.1158/1538-7445.AM2014-2314

Published: 01 October 2014

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Journal Articles

Abstract 430: Identification of novel methylation-silenced genes in oral squamous cell carcinomas

Masanobu Abe, Satoshi Yamashita, Yoshiyuki Mori, Takahiro Abe, Hideto Saijo, Toshikazu Ushijima, Tsuyoshi Takato

Cancer Res (2014) 74 (19_Supplement): 430.

DOI: https://doi.org/10.1158/1538-7445.AM2014-430

Published: 01 October 2014

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Journal Articles

Abstract 4264: Whole exome and targeted sequencing identified the MAPK and PI3K pathways as the main targets in intracranial and testicular germ cell tumors

Cancer Res (2014) 74 (19_Supplement): 4264.

DOI: https://doi.org/10.1158/1538-7445.AM2014-4264

Published: 01 October 2014

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Journal Articles

Abstract 3892: Inhibitory effects and regulatory mechanism of nestin in pancreatic cancer

Yoko Matsuda, Toshiyuki Ishiwata, Hisashi Yoshimura, Satoshi Yamashita, Toshikazu Ushijima, Kaiyo Takubo, Tomio Arai

Cancer Res (2014) 74 (19_Supplement): 3892.

DOI: https://doi.org/10.1158/1538-7445.AM2014-3892

Published: 01 October 2014

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NARROW

Abstract 1079: Distinct DNA methylation targets by aging and chronic inflammation

Abstract 3056: Development of an integrated CRISPR interference system targeting ΔNp63 to treat lung and esophageal squamous cell carcinoma

Abstract 819: DNA methylation genome-wide analysis in remnant gastric cancer

Abstract 838: Epigenetic reprogramming of different cancer-related pathways at the single cell level after low-dose DNA demethylation therapy

Abstract 843: Epigenomic disruption of adipogenic regulators in dedifferentiated liposarcoma

Abstract 5340: The methylation burden is determined by the duration of exposure to carcinogenic factors

Abstract 5331: Repression of TET genes and enhancement of DNA methyltransferase activity are critical for induction of aberrant DNA methylation

PRC2-Mediated Transcriptomic Alterations at the Embryonic Stage Govern Tumorigenesis and Clinical Outcome in MYCN-Driven Neuroblastoma

Abstract 4260: Increased mutation burden in normal-appearing lung tissues with high cancer risk

Abstract 921: Cdyl2 is a chromodomain protein involved in the maintenance of pluripotency of stem cells

Abstract LB-092: High impact of methylation accumulation on cancer risk: 5-year follow-up of a multicenter prospective cohort study

The Moment that KRAS Mutation Started to Evolve into Precision Medicine in Metastatic Colorectal Cancer

Abstract LB-245: Preclinical study of epigenetic drug-based differentiation therapy for neuroblastoma

Abstract 4460: Precision cancer risk diagnosis by accumulation of epigenetic alterations

Abstract 1048: Chromatin remodelers are frequently disrupted by epigenetic and genetic alterations at an early stage of carcinogenesis

Abstract LB-157: Demonstration of the usefulness of an epigenetic cancer risk marker by a multicenter prospective cohort study

Abstract 2314: The combination of DNA methylation and H3K27me3 is a cancer-specific dual epigenetic modification

Abstract 430: Identification of novel methylation-silenced genes in oral squamous cell carcinomas

Abstract 4264: Whole exome and targeted sequencing identified the MAPK and PI3K pathways as the main targets in intracranial and testicular germ cell tumors

Abstract 3892: Inhibitory effects and regulatory mechanism of nestin in pancreatic cancer

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