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Toshiaki Ishikawa
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Journal Articles

Abstract 3131: Novel multi-gene classifier for prediction of relapse-free survival after FU-based adjuvant chemotherapy for stage III colon cancer: A biomarker study of the ACTS-C trial, a randomized controlled study

Toshiaki Ishikawa, Kenta Murotani, Megumi Ishiguro, Eiji Nakatani, Hiroyuki Uetake, Shigeyuki Matsui, Kenichi Sugihara
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3131.
https://doi.org/10.1158/1538-7445.AM2019-3131
Published: 01 July 2019
View article titled, Abstract 3131: Novel multi-gene classifier for prediction of relapse-free survival after FU-based adjuvant chemotherapy for stage III colon cancer: A biomarker study of the ACTS-C trial, a randomized controlled study
Journal Articles

Abstract 2651: A mesenchymal-associated transcriptomic signature has a prognostic and predictive potential in stage II and III colorectal cancer patients

Takatoshi Matsuyama, Raju Kandimalla, Xuan Wang, Toshiaki Ishikawa, Naoki Takahashi, Yasuhide Yamada, Masamichi Yasuno, Yusuke Kinugasa, Hiroyuki Uetake, Ajay Goel
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2651.
https://doi.org/10.1158/1538-7445.AM2018-2651
Published: 01 July 2018
View article titled, Abstract 2651: A mesenchymal-associated transcriptomic signature has a prognostic and predictive potential in stage II and III colorectal cancer patients
Journal Articles

Abstract 1971: ITGBL1 is a novel epithelial mesenchymal transition-associated prognostic biomarker in colorectal cancer

Takatoshi Matsuyama, Toshiaki Ishikawa, Naoki Takahashi, Yasuhide Yamada, Masamichi Yasuno, Tatsuyuki Kawano, Hiroyuki Uetake, Ajay Goel
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1971.
https://doi.org/10.1158/1538-7445.AM2017-1971
Published: 01 July 2017
View article titled, Abstract 1971: ITGBL1 is a novel epithelial mesenchymal transition-associated prognostic biomarker in colorectal cancer
Journal Articles

Abstract 5274: MSI, 18q LOH, and clinicopathological features in stage II sporadic colon cancers: Biomarker study in a phase III study of postoperative adjuvant chemotherapy for stage II colon cancer (SACURA trial)

Toshiaki Ishikawa, Hiroyuki Uetake, Megumi Ishiguro, Kenta Murotani, Hideki Ueno, Shigeyuki Matsui, Kenichi Sugihara, Naohiro Tomita, SACURA study group
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5274.
https://doi.org/10.1158/1538-7445.AM2015-5274
Published: 01 August 2015
View article titled, Abstract 5274: MSI, 18q LOH, and clinicopathological features in stage II sporadic colon cancers: Biomarker study in a phase III study of postoperative adjuvant chemotherapy for stage II colon cancer (SACURA trial)
Journal Articles

Abstract CT211: Biomarker search using gene expression databases in a phase III controlled clinical trial of postoperative adjuvant chemotherapy for stage III colon cancer (ACTS-CC): correlation between clinicopathological factors and gene expression level

Hiroyuki Uetake, Toshiaki Ishikawa, Megimi Ishiguro, Shigeyuki Matsui
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): CT211.
https://doi.org/10.1158/1538-7445.AM2015-CT211
Published: 01 August 2015
View article titled, Abstract CT211: Biomarker search using gene expression databases in a phase III controlled clinical trial of postoperative adjuvant chemotherapy for stage III colon cancer (ACTS-CC): correlation between clinicopathological factors and gene expression level
Journal Articles

Abstract C18: Identification of epigenetically silenced tumor suppressor genes in colorectal cancer

Ahmed Khamas, Toshiaki Ishikawa, Satoru Iida, Megumi Ishiguro, Kazuro Shimokawa, Hiroshi Mizushima, Hiroyuki Uetake, Kenichi Sugihara
Journal: Cancer Research
Cancer Res (2011) 71 (18_Supplement): C18.
https://doi.org/10.1158/1538-7445.FBCR11-C18
Published: 28 October 2014
View article titled, Abstract C18: Identification of epigenetically silenced tumor suppressor genes in colorectal cancer
Journal Articles

Abstract 283: Biomarker search using gene expression databases in a phase III, controlled clinical trial of postoperative adjuvant chemotherapy for stage III colon cancer (acts-cc): Correlation between gene expression and DNA copy number

Hiroyuki Uetake, Toshiaki Ishikawa, Megimi Ishiguro, Shigeyuki Matsui, Kenichi Sugihara, ACTS-CC Study Group
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 283.
https://doi.org/10.1158/1538-7445.AM2014-283
Published: 01 October 2014
View article titled, Abstract 283: Biomarker search using gene expression databases in a phase III, controlled clinical trial of postoperative adjuvant chemotherapy for stage III colon cancer (acts-cc): Correlation between gene expression and DNA copy number
Journal Articles

Abstract 4688: Landscape of DNA copy number alterations of stage III colon cancer in the ACTS-CC trial (TRICC0706), a phase III trial of adjuvant chemotherapy with S-1 and UFT/LV in Japan: A comparison with Western data.

Toshiaki Ishikawa, Hiroyuki Uetake, Takashi Kobunai, Megumi Ishiguro, Shigeyuki Matsui, Kenichi Sugihara, ACTS-CC Trial Study Group
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4688.
https://doi.org/10.1158/1538-7445.AM2013-4688
Published: 15 April 2013
View article titled, Abstract 4688: Landscape of DNA copy number alterations of stage III colon cancer in the ACTS-CC trial (TRICC0706), a phase III trial of adjuvant chemotherapy with S-1 and UFT/LV in Japan: A comparison with Western data.
Journal Articles

Abstract 4684: Biomarker search using gene expression databases in a phase III, controlled clinical trial (ACTS-CC) of postoperative adjuvant chemotherapy for stage III colon cancer: Results of cluster analysis.

Hiroyuki Uetake, Toshiaki Ishikawa, Megimi Ishiguro, Kenta Murotani, Shigeyuki Matsui, Kenichi Sugihara, ACTS-CC study group
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4684.
https://doi.org/10.1158/1538-7445.AM2013-4684
Published: 15 April 2013
View article titled, Abstract 4684: Biomarker search using gene expression databases in a phase III, controlled clinical trial (ACTS-CC) of postoperative adjuvant chemotherapy for stage III colon cancer: Results of cluster analysis.
Journal Articles

Abstract 4565: Prediction of prognosis by the combination of mutation and methylation in colorectal cancer

Satoru Iida, Shunsuke Kato, Megumi Ishiguro, Toshiaki Ishikawa, Takatoshi Matsuyama, Hirotoshi Kobayashi, Tetsuro Higuchi, Hiroyuki Uetake, Kenichi Sugihara
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4565.
https://doi.org/10.1158/1538-7445.AM2012-4565
Published: 15 April 2012
View article titled, Abstract 4565: Prediction of prognosis by the combination of mutation and methylation in colorectal cancer
Journal Articles

Abstract 4516: Gene expression analysis as a biomarker study for ACTS-CC trial (TRICC0706), a phase III trial for adjuvant chemotherapy of S-1 and UFT/LV against stage III colon cancer in Japan

Hiroyuki Uetake, Toshiaki Ishikawa, Shigeyuki Matsui, Kenichi Sugihara
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4516.
https://doi.org/10.1158/1538-7445.AM2012-4516
Published: 15 April 2012
View article titled, Abstract 4516: Gene expression analysis as a biomarker study for ACTS-CC trial (TRICC0706), a phase III trial for adjuvant chemotherapy of S-1 and UFT/LV against stage III colon cancer in Japan
Journal Articles

Abstract 4534: Large-scale DNA copy number analysis as a biomarker study in the ACTS-CC trial (TRICC0706), a phase III trial of adjuvant chemotherapy with S-1 and UFT/LV in stage III colon cancer in Japan

Toshiaki Ishikawa, Hiroyuki Uetake, Shigeyuki Matsui, Megumi Ishiguro, Takashi Kobunai, Kenichi Sugihara, ACTS-CC trial Study Group.
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4534.
https://doi.org/10.1158/1538-7445.AM2012-4534
Published: 15 April 2012
View article titled, Abstract 4534: Large-scale DNA copy number analysis as a biomarker study in the ACTS-CC trial (TRICC0706), a phase III trial of adjuvant chemotherapy with S-1 and UFT/LV in stage III colon cancer in Japan
Journal Articles

Abstract 3218: High pathological CR rate and low recurrence rate was observed in liver metastasis of colorectal cancer after preoperative bevacizumab plus FOLFOX therapy

Hiroyuki Uetake, Toshiaki Ishikawa, Yusuke Mitsunori, Shinji Tanaka, Shigeki Arii, Kenichi Sugihara
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3218.
https://doi.org/10.1158/1538-7445.AM2011-3218
Published: 15 April 2011
View article titled, Abstract 3218: High pathological CR rate and low recurrence rate was observed in liver metastasis of colorectal cancer after preoperative bevacizumab plus FOLFOX therapy
Journal Articles

Abstract 3217: Influence of PIK3CA mutation and methylation of BNIP3, p16 and Dkk1 on outcome in colorectal cancer

Satoru Iida, Shunsuke Kato, Megumi Ishiguro, Toshiaki Ishikawa, Hirotoshi Kobayashi, Tetsuro Higuchi, Masayuki Enomoto, Hiroyuki Uetake, Kenichi Sugihara
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3217.
https://doi.org/10.1158/1538-7445.AM2011-3217
Published: 15 April 2011
View article titled, Abstract 3217: Influence of PIK3CA mutation and methylation of BNIP3, p16 and Dkk1 on outcome in colorectal cancer
Journal Articles

Abstract 1457: Intraoperative contrast-enhanced ultrasonography using perflubutane for liver resection

Hiroyuki Uetake, Toshiaki Ishikawa, Yusuke Mitsunori, Shinji Tanaka, Shigeki Arii, Kenichi Sugihara
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1457.
https://doi.org/10.1158/1538-7445.AM10-1457
Published: 15 April 2010
View article titled, Abstract 1457: Intraoperative contrast-enhanced ultrasonography using perflubutane for liver resection
Journal Articles

Abstract #3579: Quantitative analysis of genes using FFPE sample was dependent to dilution of a formalin solution and soaking duration: A report of the SACURA Study Group

Hiroyuki Uetake, Toshiaki Ishikawa, Hideki Ueno, Kenichi Sugihara, Naohiro Tomita
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3579.
Published: 01 May 2009
View article titled, Abstract #3579: Quantitative analysis of genes using FFPE sample was dependent to dilution of a formalin solution and soaking duration: A report of the SACURA Study Group
Journal Articles

Abstract #1623: Prognostic significance of infiltration of CD8+ T cells, MSI and 18q LOH in stage II and III colorectal cancer - A Japanese population study

Toshiaki Ishikawa, Hiroyuki Uetake, Satoru Iida, Kenichi Sugihara
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1623.
Published: 01 May 2009
View article titled, Abstract #1623: Prognostic significance of infiltration of CD8<sup>+</sup> T cells, MSI and 18q LOH in stage II and III colorectal cancer - A Japanese population study
Journal Articles

Abstract #700: Genome-wide expression analysis of colon cancer cell treated with demethylating agent identifies BNIP3 as a predictor of response to CPT-11

Satoru Iida, Sayaka Shimizu, Megumi Ishiguro, Masamichi Yasuno, Hiroyuki Uetake, Tetsuro Higuchi, Hirotoshi Kobayashi, Toshiaki Ishikawa, Masayuki Enomoto, Kenichi Sugihara
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 700.
Published: 01 May 2009
View article titled, Abstract #700: Genome-wide expression analysis of colon cancer cell treated with demethylating agent identifies BNIP3 as a predictor of response to CPT-11
Journal Articles

Promoter hypermethylation of BNIP3 was correlated to poor prognosis in colorectal cancer patients

Hiroyuki Uetake, Satoru Iida, Toshiaki Ishikawa, Sayaka Shimizu, Megumi Ishiguro, Kenichi Sugihara
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5507.
Published: 01 May 2008
View article titled, Promoter hypermethylation of BNIP3 was correlated to poor prognosis in colorectal cancer patients
Journal Articles

Influence of methylation of the Wnt-antagonist SFRP1 and Dkk1 on outcome in colorectal cancer is reversed by K-Ras mutation

Satoru Iida, Ken Hinoue, Toshiaki Ishikawa, Masamichi Yasuno, Tetsuro Higuchi, Masayuki Enomoto, Hiroyuki Uetake, Kenichi Sugihara
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 990.
Published: 01 May 2008
View article titled, Influence of methylation of the Wnt-antagonist SFRP1 and Dkk1 on outcome in colorectal cancer is reversed by K-Ras mutation