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Toru Nakamura
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Journal Articles

Abstract 2406: Circulating tumor DNA as a potential indicator of treatment response in patients with surgically unresectable PDAC

Fabio Pittella Silva, Yasutoshi Kimura, Masayo Motoya, Toru Nakamura, Takeshi Murakami, Kazunori Watanabe, Siew-Kee Low, Yusuke Nakamura
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2406.
https://doi.org/10.1158/1538-7445.AM2024-2406
Published: 22 March 2024
View article titled, Abstract 2406: Circulating tumor DNA as a potential indicator of treatment response in patients with surgically unresectable PDAC
Journal Articles

Abstract 4393: Expression levels of T-cell factor-4 variants in hepato-gastrointestinal cancer cells and tissues

Hironori Koga, Yasuko Imamura, Tomoya Sudo, Hiroyuki Suzuki, Toshimitsu Tanaka, Takahiko Sakaue, Atsutaka Masuda, Hideki Iwamoto, Toru Nakamura, Hirohisa Yano, Takumi Kawaguchi
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4393.
https://doi.org/10.1158/1538-7445.AM2024-4393
Published: 22 March 2024
View article titled, Abstract 4393: Expression levels of T-cell factor-4 variants in hepato-gastrointestinal cancer cells and tissues
Journal Articles

Abstract 3659: Development of customized circulating tumor DNA panel for minimal residual disease detection in biliary tract cancer

Yoshihito Shinohara, Siew-Kee Low, Toru Nakamura, Yasutoshi Kimura, Takeshi Murakami, Kazuma Kiyotani, Satoshi Hirano
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 3659.
https://doi.org/10.1158/1538-7445.AM2024-3659
Published: 22 March 2024
View article titled, Abstract 3659: Development of customized circulating tumor DNA panel for minimal residual disease detection in biliary tract cancer
Journal Articles

Drosophila Screening Identifies Dual Inhibition of MEK and AURKB as an Effective Therapy for Pancreatic Ductal Adenocarcinoma

Sho Sekiya, Junki Fukuda, Ryodai Yamamura, Takako Ooshio, Yusuke Satoh, Shinya Kosuge, Reo Sato, Kanako C. Hatanaka, Yutaka Hatanaka, Tomoko Mitsuhashi, Toru Nakamura, Yoshihiro Matsuno, Satoshi Hirano, Masahiro Sonoshita
Journal: Cancer Research
Cancer Res (2023) 83 (16): 2704–2715.
https://doi.org/10.1158/0008-5472.CAN-22-3762
Published: 15 August 2023
View article titled, <em>Drosophila</em> Screening Identifies Dual Inhibition of MEK and AURKB as an Effective Therapy for Pancreatic Ductal Adenocarcinoma
Open the PDF for <em>Drosophila</em> Screening Identifies Dual Inhibition of MEK and AURKB as an Effective Therapy for Pancreatic Ductal Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 5870: T-cell factor-4 variants regulate PD-L1 expression in liver cancer cells

Hironori Koga, Yasuko Imamura, Toshimitsu Tanaka, Hideki Iwamoto, Toru Nakamura, Atsutaka Masuda, Takahiko Sakaue, Hiroyuki Suzuki, Hirohisa Yano, Takumi Kawaguchi
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5870.
https://doi.org/10.1158/1538-7445.AM2023-5870
Published: 04 April 2023
View article titled, Abstract 5870: T-cell factor-4 variants regulate PD-L1 expression in liver cancer cells
Journal Articles

Abstract 3137: Pancreatic juice biomarker for detection of early stage pancreatic cancer using tumor-specific exosomal microRNAs

Takahiko Sakaue, Hideki Iwamoto, Hironori Koga, Yasuko Imamura, Toru Nakamura, Atsutaka Masuda, Toshimitsu Tanaka, Hiroyuki Suzuki, Tomoyuki Ushijima, Yoshinobu Okabe, Takuji Torimura
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3137.
https://doi.org/10.1158/1538-7445.AM2020-3137
Published: 15 August 2020
View article titled, Abstract 3137: Pancreatic juice biomarker for detection of early stage pancreatic cancer using tumor-specific exosomal microRNAs
Journal Articles

Abstract 2627: Opposite functions of Claudin-2 involving Wnt signaling in liver cancer cells

Hironori Koga, Yasuko Imamura, Toru Nakamura, Hideki Iwamoto, Takahiko Sakaue, Atsutaka Masuda, Toshimitsu Tanaka, Dan Nakano, Hiroyuki Suzuki, Hirohisa Yano, Takuji Torimura
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2627.
https://doi.org/10.1158/1538-7445.AM2020-2627
Published: 15 August 2020
View article titled, Abstract 2627: Opposite functions of Claudin-2 involving Wnt signaling in liver cancer cells
Journal Articles

Abstract 2660: Glycosylation of ascites-derived exosomal CD133 is a potential prognostic biomarker in patients with advanced pancreatic cancer

Takahiko Sakaue, Hironori Koga, Hideki Iwamoto, Yasuko Imamura, Toru Nakamura, Mitsuhiko Abe, Fumitaka Wada, Atsutaka Masuda, Toshimitsu Tanaka, Masaru Fukahori, Tomoyuki Ushijima, Yoshinobu Okabe, Tatsuyuki Kakuma, Takuji Torimura
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2660.
https://doi.org/10.1158/1538-7445.AM2018-2660
Published: 01 July 2018
View article titled, Abstract 2660: Glycosylation of ascites-derived exosomal CD133 is a potential prognostic biomarker in patients with advanced pancreatic cancer
Journal Articles

Abstract 2574: Biglycan, tumor endothelial secreting proteoglycan, as possible biomarker for lung cancer

Hirofumi Morimoto, Nako Maishi, Yasuhiro Hida, Hiroshi Nishihara, Yutaka Hatanaka, Yoshihiro Matsuno, Toru Nakamura, Satoshi Hirano, Kyoko Hida
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2574.
https://doi.org/10.1158/1538-7445.AM2018-2574
Published: 01 July 2018
View article titled, Abstract 2574: Biglycan, tumor endothelial secreting proteoglycan, as possible biomarker for lung cancer
Journal Articles

Abstract 4029: The Wnt target gene CLAUDIN-2 regulates tumorigenesis and stemness in human liver cancer cells

Hironori Koga, Fumitaka Wada, Mitsuhiko Abe, Hideki Iwamoto, Toru Nakamura, Takahiko Sakaue, Atsutaka Masuda, Toshimitsu Tanaka, Hirohisa Yano, Takuji Torimura
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4029.
https://doi.org/10.1158/1538-7445.AM2018-4029
Published: 01 July 2018
View article titled, Abstract 4029: The Wnt target gene <em>CLAUDIN-2</em> regulates tumorigenesis and stemness in human liver cancer cells
Journal Articles

Abstract 3955: Expression of cancer stem cell-associated proteins in exosomes derived from ascites of patients with advanced pancreatic cancer

Takahiko Sakaue, Hironori Koga, Masaru Fukahori, Yasuko Imamura, Toru Nakamura, Yoshinobu Okabe, Yu Ikezono, Fumitaka Wada, Hideki Iwamoto, Atsutaka Masuda, Tomoyuki Ushijima, Keisuke Miwa, Tatsuyuki Kakuma, Osamu Tsuruta, Takuji Torimura
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3955.
https://doi.org/10.1158/1538-7445.AM2016-3955
Published: 15 July 2016
View article titled, Abstract 3955: Expression of cancer stem cell-associated proteins in exosomes derived from ascites of patients with advanced pancreatic cancer
Journal Articles

Abstract 4601: Regulation of Hes1 expression by the Wnt transcription factor T-cell factor-4

Hironori Koga, Yasuko Imamura, Yu Ikezono, Fumitaka Wada, Toru Nakamura, Hideki Iwamoto, Atsutaka Masuda, Takahiko Sakaue, Hirohisa Yano, Takuji Torimura
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4601.
https://doi.org/10.1158/1538-7445.AM2016-4601
Published: 15 July 2016
View article titled, Abstract 4601: Regulation of Hes1 expression by the Wnt transcription factor T-cell factor-4
Journal Articles

Abstract 1728: DCLK1 promotes tumor growth and invasion through Slug-mediated epithelial-mesenchymal transition in pancreatic neuroendocrine tumors

Yu Ikezono, Hironori Koga, Jun Akiba, Mitsuhiko Abe, Fumitaka Wada, Toru Nakamura, Hideki Iwamoto, Atsutaka Masuda, Takahiko Sakaue, Hirohisa Yano, Osamu Tsuruta, takuji Torimura
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1728.
https://doi.org/10.1158/1538-7445.AM2016-1728
Published: 15 July 2016
View article titled, Abstract 1728: DCLK1 promotes tumor growth and invasion through Slug-mediated epithelial-mesenchymal transition in pancreatic neuroendocrine tumors
Journal Articles

Abstract 3890: Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity

Hidewaki Nakagawa, Akihiro Fujimoto, Mayuko Furuta, Kunihito Gotoh, Toru Nakamura, Masakazu Yamamoto, Hiroki Yamaue, Kazuaki Chayama, Satoru Miyano, Tatsuhiko Tsunoda
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3890.
https://doi.org/10.1158/1538-7445.AM2015-3890
Published: 01 August 2015
View article titled, Abstract 3890: Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity
Journal Articles

Abstract 1436: The SxxSS motif of T-cell Factor-4 isoforms regulates Wnt5a expression and EMT in human liver cancer cells

Hironori Koga, Toru Nakamura, Mitsuhiko Abe, Yu Ikezono, Fumitaka Wada, Hirohisa Yano, Takuji Torimura
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1436.
https://doi.org/10.1158/1538-7445.AM2015-1436
Published: 01 August 2015
View article titled, Abstract 1436: The SxxSS motif of T-cell Factor-4 isoforms regulates Wnt5a expression and EMT in human liver cancer cells
Journal Articles

Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer

Shintaro Takeuchi, Muhammad Baghdadi, Takahiro Tsuchikawa, Haruka Wada, Toru Nakamura, Hirotake Abe, Sayaka Nakanishi, Yuu Usui, Kohtaro Higuchi, Mizuna Takahashi, Kazuho Inoko, Syoki Sato, Hironobu Takano, Toshiaki Shichinohe, Ken-ichiro Seino, Satoshi Hirano
Journal: Cancer Research
Cancer Res (2015) 75 (13): 2629–2640.
https://doi.org/10.1158/0008-5472.CAN-14-2921
Published: 30 June 2015
View article titled, Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer
Open the PDF for Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1047: The multikinase inhibitor K252a suppresses hepatocellular carcinoma tumor growth in a mouse xenograft model

Mitsuhiko Abe, Hironori Koga, Takafumi Yoshida, Hiroshi Masuda, Masahiro Sakata, Yu Ikezono, Toru Nakamura, Eitaro Taniguchi, Takumi Kawaguchi, Hirohisa Yano, Takuji Torimura, Michio Sata
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1047.
https://doi.org/10.1158/1538-7445.AM2014-1047
Published: 01 October 2014
View article titled, Abstract 1047: The multikinase inhibitor K252a suppresses hepatocellular carcinoma tumor growth in a mouse xenograft model
Journal Articles

Abstract 330: The Wnt signal transcription factor TCF-4 directly regulates Bcl-xL expression in human hepatocellular carcinoma cells

Hironori Koga, Miran Kim, Anna Nakamura, Hirohisa Yano, Mitsuhiko Abe, Yu Ikezono, Toru Nakamura, Takuji Torimura, Jack R. Wands, Michio Sata
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 330.
https://doi.org/10.1158/1538-7445.AM2014-330
Published: 01 October 2014
View article titled, Abstract 330: The Wnt signal transcription factor TCF-4 directly regulates Bcl-xL expression in human hepatocellular carcinoma cells
Journal Articles

Abstract 3050: Human rectal carcinoid tumors highly express DCLK1, a putative cancer stem cell marker

Yu Ikezono, Hironori Koga, Mitsuhiko Abe, Takafumi Yoshida, Toru Nakamura, Jun Akiba, Hirohisa Yano, Osamu Tsuruta, Takuji Torimura, Michio Sata
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3050.
https://doi.org/10.1158/1538-7445.AM2014-3050
Published: 01 October 2014
View article titled, Abstract 3050: Human rectal carcinoid tumors highly express DCLK1, a putative cancer stem cell marker
Journal Articles

Abstract 890: Human TCF-4 isoforms regulate apoptosis through upregulating Bcl-xL expression in a SxxSS motif-dependent manner.

Hironori Koga, Miran Kim, Yoshito Tomimaru, Toru Nakamura, Mitsuhiko Abe, Osamu Hashimoto, Yu Ikezono, Hiroshi Masuda, Hirohisa Yano, Takato Ueno, Takuji Torimura, Jack R. Wands, Michio Sata
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 890.
https://doi.org/10.1158/1538-7445.AM2013-890
Published: 15 April 2013
View article titled, Abstract 890: Human TCF-4 isoforms regulate apoptosis through upregulating Bcl-xL expression in a SxxSS motif-dependent manner.