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Abstract 4394: Identification of molecular determinants of response to GSK1120212B, a potent and selective MEK inhibitor, as a single agent and in combination in RAS/RAF mutant non-small cell lung carcinoma cells

Li Liu, Shi Hong, Vivian Zhang, Tona Gilmer

Cancer Res (2011) 71 (8_Supplement): 4394.

https://doi.org/10.1158/1538-7445.AM2011-4394

Published: 15 April 2011

View articletitled, Abstract 4394: Identification of molecular determinants of response to GSK1120212B, a potent and selective MEK inhibitor, as a single agent and in combination in RAS/RAF mutant non-small cell lung carcinoma cells

Journal Articles

Abstract #1746: GSK1363089 inhibits MET and synergizes with HER targeted agents in MET amplified/over-expressed and HER1/HER2 amplified tumor cells

Hong Shi, Li Liu, James Greger, Tona Gilmer

Cancer Res (2009) 69 (9_Supplement): 1746.

Published: 01 May 2009

View articletitled, Abstract #1746: GSK1363089 inhibits MET and synergizes with HER targeted agents in MET amplified/over-expressed and HER1/HER2 amplified tumor cells

Journal Articles

Abstract #858: Personalizing chemotherapy to improve esophago-gastric cancer outcomes

Anna Paterson, Tona Gilmer, Richard Wooster, Rebecca Fitzgerald

Cancer Res (2009) 69 (9_Supplement): 858.

Published: 01 May 2009

View articletitled, Abstract #858: Personalizing chemotherapy to improve esophago-gastric cancer outcomes

Journal Articles

Abstract #LB-194: Novel mechanism of resistance to HER-targeted agents in HER2+ breast tumor cells: Overexpression of the receptor tyrosine kinase AXL

James Greger, Hong Shi, Yuan Liu, Joel Greshock, Roland Annan, Wendy Halsey, Ganesh Sathe, Anne-Marie Martin, Li Liu, Tona Gilmer

Cancer Res (2009) 69 (9_Supplement): LB-194.

Published: 01 May 2009

View articletitled, Abstract #LB-194: Novel mechanism of resistance to HER-targeted agents in HER2+ breast tumor cells: Overexpression of the receptor tyrosine kinase AXL

Journal Articles

Lapatinib in combination with platinum agents in head and neck and gastric cancer cells

Li Liu, Hong Shi, Tona Gilmer

Cancer Res (2008) 68 (9_Supplement): 4019.

Published: 01 May 2008

View articletitled, Lapatinib in combination with platinum agents in head and neck and gastric cancer cells

Journal Articles

Lapatinib reduces the activation of Her-2 but not EGFR in brain metastases of the MDA-MB-231BR human breast carcinoma cell line

Brunilde Gril, Diane Palmieri, Eleazar Vega-Valle, Jeanne Herring, Emily Hua, Lionel Feigenbaum, David Liewehr, Seth Steinberg, Tona Gilmer, Stephen Rubin, Patricia Steeg

Cancer Res (2008) 68 (9_Supplement): 5836.

Published: 01 May 2008

View articletitled, Lapatinib reduces the activation of Her-2 but not EGFR in brain metastases of the MDA-MB-231BR human breast carcinoma cell line

Journal Articles

GSK690693, a pan-AKT kinase inhibitor with potent pharmacodynamic and antitumor activity in vivo.

Rakesh Kumar, Nelson Rhodes, Victoria Knick, Derek Eberwein, Derek Duckett, ShuYun Zhang, Tona Gilmer, Jack Leber, Elena Kleymenova, Rob Geske, Elisabeth Minthorn, Dirk Heerding, Pearl Huang

Cancer Res (2007) 67 (9_Supplement): 277.

Published: 01 May 2007

View articletitled, GSK690693, a pan-AKT kinase inhibitor with potent pharmacodynamic and antitumor activity in vivo.

Journal Articles

Lapatinib: A novel approach to inhibit EGFR(ErbB1)/HER2(ErbB2)

Tona Gilmer

Cancer Res (2007) 67 (9_Supplement): SY04-01.

Published: 01 May 2007

View articletitled, Lapatinib: A novel approach to inhibit EGFR(ErbB1)/HER2(ErbB2)

Journal Articles

Lapatinib prevents the metastatic colonization of EGFR+ and Her-2+ breast cancer cells in the brain.

Brunilde Gril, Diane Palmieri, Eleazar Vega-Valle, Emily Hua, Jeanne Herring, Tona Gilmer, Stephen Rubin, Patricia Steeg

Cancer Res (2007) 67 (9_Supplement): 4081.

Published: 01 May 2007

View articletitled, Lapatinib prevents the metastatic colonization of EGFR+ and Her-2+ breast cancer cells in the brain.

Journal Articles

The combination of lapatinib (GW572016F) and agents targeting the insulin-like growth factor I receptor results in synergistic tumor cell growth inhibition and induction of apoptosis

David Rusnak, Rakesh Kumar, Tona Gilmer

Cancer Res (2007) 67 (9_Supplement): 5739.

Published: 01 May 2007

View articletitled, The combination of lapatinib (GW572016F) and agents targeting the insulin-like growth factor I receptor results in synergistic tumor cell growth inhibition and induction of apoptosis

Journal Articles

GSK690693, a pan-AKT kinase inhibitor has potent anti-tumor activity and shows additive effect with lapatinib.

Nelson Rhodes, Victoria Knick, Randy McConnell, Timothy Lansing, David Rusnak, Derek Duckett, Tona Gilmer, Jason Kahana, Kimerly Robell, Jack Leber, Anthony Choudhry, Zhihong Lai, Edgar Wood, Susan Strum, Dirk Heerding, Pearl Huang, Rakesh Kumar

Cancer Res (2007) 67 (9_Supplement): 279.

Published: 01 May 2007

View articletitled, GSK690693, a pan-AKT kinase inhibitor has potent anti-tumor activity and shows additive effect with lapatinib.

Journal Articles

Identification of a novel inhibitor of AKT kinase, GSK690693.

Cancer Res (2007) 67 (9_Supplement): ND-2.

Published: 01 May 2007

View articletitled, Identification of a novel inhibitor of AKT kinase, GSK690693.

Journal Articles

Cellular pharmacogenomic to discover genetic determinants of Tykerb response

Holly Yin, Qiang Que, Donald Chow, Christian Beaudry, Pinar Tuzmen, Leslie Gwinn, Jeff Kiefer, Michael Barrett, David Azorsa, Sukru Tuzmen, Tal Zachs, Richard Wooster, Tona Gilmer, Barbara Weber, Spyro Mousses

Cancer Res (2007) 67 (9_Supplement): 5684.

Published: 01 May 2007

View articletitled, Cellular pharmacogenomic to discover genetic determinants of Tykerb response

Journal Articles

Biomarker analyses of PLK isoforms in breast cancer

Yan Y. Degenhardt, Katja Remlinger, Joel Greshock, Tal Zaks, Barbara Weber, Tona Gilmer

Cancer Res (2006) 66 (8_Supplement): 459.

Published: 15 April 2006

View articletitled, Biomarker analyses of PLK isoforms in breast cancer

Journal Articles

A New Ligand for the Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ), GW7845, Inhibits Rat Mammary Carcinogenesis

Nanjoo Suh, Yongping Wang, Charlotte R. Williams, Renee Risingsong, Tona Gilmer, Timothy M. Willson, Michael B. Sporn

Cancer Res (1999) 59 (22): 5671–5673.

Published: 01 November 1999

View articletitled, A New Ligand for the Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ), GW7845, Inhibits Rat Mammary Carcinogenesis

Journal Articles

Mouse Retroviral Sequences Acquired by Cell Lines after Passaging through Nude Mice Detected by Hybridization of the fms Probe pSM3

Cheryl Walker, Paul Nettesheim, J. Carl Barrett, Frank R. Jirik, Joseph Sorge, Marianne Joyce, Tona Gilmer

Cancer Res (1989) 49 (3): 625–628.

Published: 01 February 1989

View articletitled, Mouse Retroviral Sequences Acquired by Cell Lines after Passaging through Nude Mice Detected by Hybridization of the fms Probe pSM3

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Abstract 4394: Identification of molecular determinants of response to GSK1120212B, a potent and selective MEK inhibitor, as a single agent and in combination in RAS/RAF mutant non-small cell lung carcinoma cells

Abstract #1746: GSK1363089 inhibits MET and synergizes with HER targeted agents in MET amplified/over-expressed and HER1/HER2 amplified tumor cells

Abstract #858: Personalizing chemotherapy to improve esophago-gastric cancer outcomes

Abstract #LB-194: Novel mechanism of resistance to HER-targeted agents in HER2+ breast tumor cells: Overexpression of the receptor tyrosine kinase AXL

Lapatinib in combination with platinum agents in head and neck and gastric cancer cells

Lapatinib reduces the activation of Her-2 but not EGFR in brain metastases of the MDA-MB-231BR human breast carcinoma cell line

GSK690693, a pan-AKT kinase inhibitor with potent pharmacodynamic and antitumor activity in vivo.

Lapatinib: A novel approach to inhibit EGFR(ErbB1)/HER2(ErbB2)

Lapatinib prevents the metastatic colonization of EGFR+ and Her-2+ breast cancer cells in the brain.

The combination of lapatinib (GW572016F) and agents targeting the insulin-like growth factor I receptor results in synergistic tumor cell growth inhibition and induction of apoptosis

GSK690693, a pan-AKT kinase inhibitor has potent anti-tumor activity and shows additive effect with lapatinib.

Identification of a novel inhibitor of AKT kinase, GSK690693.

Cellular pharmacogenomic to discover genetic determinants of Tykerb response

Biomarker analyses of PLK isoforms in breast cancer

A New Ligand for the Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ), GW7845, Inhibits Rat Mammary Carcinogenesis

Mouse Retroviral Sequences Acquired by Cell Lines after Passaging through Nude Mice Detected by Hybridization of the fms Probe pSM3

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