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Ton N. Schumacher
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Journal Articles

Immunological Tolerance to Luciferase and Fluorescent Proteins using Tol Mice Enables Development of Improved Tumor Models for Investigating Immunity and Metastasis

Kabir A. Khan, Areeba A. Qureshi, Ping Xu, Hung-Yang Kuo, Ton N. Schumacher, Iacovos P. Michael, Robert S. Kerbel
Journal: Cancer Research
Cancer Res (2025)
https://doi.org/10.1158/0008-5472.CAN-24-2418
Published: 14 April 2025
View articletitled, Immunological Tolerance to Luciferase and Fluorescent Proteins using Tol Mice Enables Development of Improved Tumor Models for Investigating Immunity and Metastasis
Open the PDF for Immunological Tolerance to Luciferase and Fluorescent Proteins using Tol Mice Enables Development of Improved Tumor Models for Investigating Immunity and Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 2281: Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activated Treg compartment

Anne M. van der Leun, Joleen J. Traets, Joris L. Vos, Joris B. Elbers, Sanne Patiwael, Xiaohang Qiao, Mercedes Machuca-Ostos, Daniela S. Thommen, John B. Haanen, Ton N. Schumacher, Charlotte L. Zuur
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2281.
https://doi.org/10.1158/1538-7445.AM2023-2281
Published: 04 April 2023
View articletitled, Abstract 2281: Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activated Treg compartment
Journal Articles

Abstract 561: CAR-targeted IL-2 drives selective CAR-T cell expansion and improves anti-tumor efficacy

Nathan D. Mathewson, Kelly D. Moynihan, Sara Sleiman, Wei Chen, Paul Bessette, Christopher Kimberlin, Eric Wigton, Danielle Pappas, Terrence Park, Ton N. Schumacher, Saar I. Gill, Yik Andy Yeung, Ivana Djuretic
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 561.
https://doi.org/10.1158/1538-7445.AM2022-561
Published: 15 June 2022
View articletitled, Abstract 561: CAR-targeted IL-2 drives selective CAR-T cell expansion and improves anti-tumor efficacy
Journal Articles

Abstract 3518: AB248 is a CD8+ T cell selective IL-2 designed for superior safety and anti-tumor efficacy

Kelly D. Moynihan, Danielle Pappas, Terrence Park, Wei Chen, Irene Ni, Paul Bessette, Henry Nguyen, David Liu, Mike Chin, Ruth Lan, Aaron Arvey, Ton N. Schumacher, Yik Andy Yeung, Ivana Djuretic
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3518.
https://doi.org/10.1158/1538-7445.AM2022-3518
Published: 15 June 2022
View articletitled, Abstract 3518: AB248 is a CD8+ T cell selective IL-2 designed for superior safety and anti-tumor efficacy
Journal Articles

Abstract 3210: Strategies to improve the sensitivity and ranking ability of neoantigen prediction methods: Report on the results of the Tumor nEoantigen SeLection Alliance (TESLA)

Daniel K. Wells, Kristen Dang, Vanessa M. Hubbard-Lucey, Kathleen C. Sheehan, Andrew Lamb, Jeffrey P. Ward, John Sidney, Ana B. Blazquez, Andrew J. Rech, Jesse Zaretsky, Begonya Comin-Anduix, Alphonsus H. Ng, William Chour, Thomas V. Yu, Hira Rizvi, Jia Chen, Patrice Manning, Taha Merghoub, Justin Guinney, Adam Kolom, Cheryl Selinsky, Antoni Ribas, Matthew D. Hellmann, Ton N. Schumacher, Nir Hacohen, Pia Kvistborg, Alessandro Sette, James R. Heath, Nina Bhardwaj, Fred Ramsdell, Robert D. Schreiber, Nadine A. Defranoux, TESLA Consortium
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3210.
https://doi.org/10.1158/1538-7445.AM2020-3210
Published: 15 August 2020
View articletitled, Abstract 3210: Strategies to improve the sensitivity and ranking ability of neoantigen prediction methods: Report on the results of the Tumor nEoantigen SeLection Alliance (TESLA)
Journal Articles

Abstract 3412: 36-months and 18-months relapse-free survival after (neo)adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma patients - update of the OpACIN and OpACIN-neo trials

Christian U. Blank, Judith M. Versluis, Elisa A. Rozeman, Alexander M. Menzies, Irene L. Reijers, Oscar Krijgsman, Esmée P. Hoefsmit, Bart A. van de Wiel, Karolina Sikorska, Carolien Bierman, Petros Dimitriadis, Maria Gonzalez, Annegien Broeks, Ron M. Kerkhoven, Andrew J. Spillane, John B. Haanen, Winan J. van Houdt, Robyn P. Saw, Hanna Eriksson, Alexander C. van Akkooi, Richard A. Scolyer, Ton N. Schumacher, Georgina V. Long
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3412.
https://doi.org/10.1158/1538-7445.AM2020-3412
Published: 15 August 2020
View articletitled, Abstract 3412: 36-months and 18-months relapse-free survival after (neo)adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma patients - update of the OpACIN and OpACIN-neo trials
Journal Articles

Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling

Marco Donia, Katja Harbst, Marit van Buuren, Pia Kvistborg, Mattias F. Lindberg, Rikke Andersen, Manja Idorn, Shamaila Munir Ahmad, Eva Ellebæk, Anja Mueller, Paolo Fagone, Ferdinando Nicoletti, Massimo Libra, Martin Lauss, Sine Reker Hadrup, Henrik Schmidt, Mads Hald Andersen, Per thor Straten, Jonas A. Nilsson, Ton N. Schumacher, Barbara Seliger, Göran Jönsson, Inge Marie Svane
Journal: Cancer Research
Cancer Res (2017) 77 (17): 4562–4566.
https://doi.org/10.1158/0008-5472.CAN-16-3172
Published: 31 August 2017
View articletitled, Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling
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Includes: Supplementary data
Journal Articles

Abstract LB-291: Identification of CMTM6 and CMTM4 as PD-L1 protein regulators

Chong Sun, Riccardo Mezzadra, Lucas T. Jae, Raquel Gomez-Eerland, Evert de Vries, Wei Wu, Yanling Xiao, Albert J. Heck, Jannie Borst, Thijn R. Brummelkamp, Ton N. Schumacher
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-291.
https://doi.org/10.1158/1538-7445.AM2017-LB-291
Published: 01 July 2017
View articletitled, Abstract LB-291: Identification of CMTM6 and CMTM4 as PD-L1 protein regulators
Journal Articles

T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors

Teresa Manzo, Tabea Sturmheit, Veronica Basso, Elisabetta Petrozziello, Rodrigo Hess Michelini, Michela Riba, Massimo Freschi, Angela R. Elia, Matteo Grioni, Flavio Curnis, Maria Pia Protti, Ton N. Schumacher, Reno Debets, Melody A. Swartz, Angelo Corti, Matteo Bellone, Anna Mondino
Journal: Cancer Research
Cancer Res (2017) 77 (3): 658–671.
https://doi.org/10.1158/0008-5472.CAN-16-0725
Published: 31 January 2017
View articletitled, T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors
Open the PDF for T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors in another window
Includes: Supplementary data
Journal Articles

Dissection of T-cell Antigen Specificity in Human Melanoma

Rikke Sick Andersen, Charlotte Albæk Thrue, Niels Junker, Rikke Lyngaa, Marco Donia, Eva Ellebæk, Inge Marie Svane, Ton N. Schumacher, Per thor Straten, Sine Reker Hadrup
Journal: Cancer Research
Cancer Res (2012) 72 (7): 1642–1650.
https://doi.org/10.1158/0008-5472.CAN-11-2614
Published: 01 April 2012
View articletitled, Dissection of T-cell Antigen Specificity in Human Melanoma
Open the PDF for Dissection of T-cell Antigen Specificity in Human Melanoma in another window
Includes: Supplementary data