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Tomoyuki Shirai
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Journal Articles

Abstract 672: Histone deacetylase inhibition has potential to suppresse growth of androgen dependent and independent prostate cancer in vitro and in vivo.

Free
Shinya Sato, Shugo Suzuki, Aya Naiki-Ito, Yoriko Yamashita, Makoto Asamoto, Tomoyuki Shirai, Satoru Takahashi
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 672.
https://doi.org/10.1158/1538-7445.AM2013-672
Published: 15 April 2013
View articletitled, Abstract 672: Histone deacetylase inhibition has potential to suppresse growth of androgen dependent and independent prostate cancer in vitro and in vivo.
Journal Articles

Abstract 4980: Age dependent carcinogenic susceptibility of rat liver is related to potential of gap junctional intercellular communication

Free
Aya Naiki-Ito, Makoto Asamoto, Satoru Takahashi, Tomoyuki Shirai
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4980.
https://doi.org/10.1158/1538-7445.AM2012-4980
Published: 15 April 2012
View articletitled, Abstract 4980: Age dependent carcinogenic susceptibility of rat liver is related to potential of gap junctional intercellular communication
Journal Articles

Methylation Silencing of Transforming Growth Factor-β Receptor Type II in Rat Prostate Cancers

Free
Satoshi Yamashita, Satoru Takahashi, Nathalie McDonell, Naoko Watanabe, Tohru Niwa, Kosuke Hosoya, Yoshimi Tsujino, Tomoyuki Shirai, Toshikazu Ushijima
Journal: Cancer Research
Cancer Res (2008) 68 (7): 2112–2121.
https://doi.org/10.1158/0008-5472.CAN-07-5282
Published: 01 April 2008
View articletitled, Methylation Silencing of Transforming Growth Factor-β Receptor Type II in Rat Prostate Cancers
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Includes: Supplementary data
Journal Articles

Gpx2 Is an Overexpressed Gene in Rat Breast Cancers Induced by Three Different Chemical Carcinogens

Free
Aya Naiki-Ito, Makoto Asamoto, Naomi Hokaiwado, Satoru Takahashi, Hiroko Yamashita, Hiroyuki Tsuda, Kumiko Ogawa, Tomoyuki Shirai
Journal: Cancer Research
Cancer Res (2007) 67 (23): 11353–11358.
https://doi.org/10.1158/0008-5472.CAN-07-2226
Published: 03 December 2007
View articletitled, Gpx2 Is an Overexpressed Gene in Rat Breast Cancers Induced by Three Different Chemical Carcinogens
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Journal Articles

TGF-β directly and indirectly promote mammary tumor growth in the bone microenvironment by increasing osteoclastgenesis

Free
Mitsuru Futakuchi, Michelle L. Varney, Anguraji Sadanandam, Kimihisa Nakao, Kiyofumi Asai, Tomoyuki Shirai, Rakesh K. Singh
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 393.
Published: 15 April 2006
View articletitled, TGF-β directly and indirectly promote mammary tumor growth in the bone microenvironment by increasing osteoclastgenesis
Journal Articles

Canonical and noncanonical Wnt gene expression is differentially altered in a transgenic rat prostate cancer model.

Free
Yongbing Pu, Zhouhua Wang, Liwei Huang, Tomoyuki Shirai, Steve Swanson, Gail S. Prins
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1182–1183.
Published: 15 April 2006
View articletitled, Canonical and noncanonical Wnt gene expression is differentially altered in a transgenic rat prostate cancer model.
Journal Articles

Linkage and Microarray Analyses of Susceptibility Genes in ACI/Seg Rats: A Model for Prostate Cancers in the Aged

Free
Satoshi Yamashita, Shugo Suzuki, Tomoko Nomoto, Yasushi Kondo, Kuniko Wakazono, Yoshimi Tsujino, Takashi Sugimura, Tomoyuki Shirai, Yukio Homma, Toshikazu Ushijima
Journal: Cancer Research
Cancer Res (2005) 65 (7): 2610–2616.
https://doi.org/10.1158/0008-5472.CAN-04-2932
Published: 01 April 2005
View articletitled, Linkage and Microarray Analyses of Susceptibility Genes in ACI/Seg Rats: A Model for Prostate Cancers in the Aged
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Includes: Supplementary data
Journal Articles

Mechanism analysis of hormetic effect using three dimension microarray system.

Free
Natsuko Miyazi, Keiichirou Morimura, Anna Kinoshita, Hideki Wanibuchi, Jin Seok Kang, Makoto Asamoto, Naomi Hokaiwado, Tomoyuki Shirai, Shoji Fukushima
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 747.
Published: 01 April 2004
View articletitled, Mechanism analysis of hormetic effect using three dimension microarray system.
Journal Articles

Lack of Mutation Induction with Exposure to 1.5 GHz Electromagnetic Near Fields Used for Cellular Phones in Brains of Big Blue Mice

Free
Satoru Takahashi, Shingo Inaguma, Young-Man Cho, Katsumi Imaida, Jianqing Wang, Osamu Fujiwara, Tomoyuki Shirai
Journal: Cancer Research
Cancer Res (2002) 62 (7): 1956–1960.
Published: 01 April 2002
View articletitled, Lack of Mutation Induction with Exposure to 1.5 GHz Electromagnetic Near Fields Used for Cellular Phones in Brains of Big Blue Mice
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Journal Articles

Prostate Carcinomas Developing in Transgenic Rats with SV40 T Antigen Expression under Probasin Promoter Control Are Strictly Androgen Dependent

Free
Makoto Asamoto, Naomi Hokaiwado, Young-Man Cho, Satoru Takahashi, Yoshihisa Ikeda, Katsumi Imaida, Tomoyuki Shirai
Journal: Cancer Research
Cancer Res (2001) 61 (12): 4693–4700.
Published: 01 June 2001
View articletitled, Prostate Carcinomas Developing in Transgenic Rats with SV40 T Antigen Expression under Probasin Promoter Control Are Strictly Androgen Dependent
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Journal Articles

Immunohistochemical Demonstration of Carcinogen-DNA Adducts in Tissues of Rats Given 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): Detection in Paraffin-embedded Sections and Tissue Distribution

Free
Satoru Takahashi, Seiko Tamano, Masao Hirose, Naoya Kimoto, Yoshihisa Ikeda, Michihisa Sakakibara, Mariko Tada, Fred F. Kadlubar, Nobuyuki Ito, Tomoyuki Shirai
Journal: Cancer Research
Cancer Res (1998) 58 (19): 4307–4313.
Published: 01 October 1998
View articletitled, Immunohistochemical Demonstration of Carcinogen-DNA Adducts in Tissues of Rats Given 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): Detection in Paraffin-embedded Sections and Tissue Distribution
Open the PDF for Immunohistochemical Demonstration of Carcinogen-DNA Adducts in Tissues of Rats Given 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): Detection in Paraffin-embedded Sections and Tissue Distribution in another window
Journal Articles

The Prostate: A Target for Carcinogenicity of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Derived from Cooked Foods

Free
Tomoyuki Shirai, Masashi Sano, Seiko Tamano, Satoru Takahashi, Masao Hirose, Mitsuru Futakuchi, Ryohei Hasegawa, Katsumi Imaida, Ken-ichiro Matsumoto, Keiji Wakabayashi, Takashi Sugimura, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1997) 57 (2): 195–198.
Published: 01 January 1997
View articletitled, The Prostate: A Target for Carcinogenicity of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Derived from Cooked Foods
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Journal Articles

Chemoprevention by Dehydroepiandrosterone and Indomethacin in a Rat Multiorgan Carcinogenesis Model

Free
Masa-Aki Shibata, Ryohei Hasegawa, Katsumi Imaida, Akihiro Hagiwara, Kumiko Ogawa, Masao Hirose, Nobuyuki Ito, Tomoyuki Shirai
Journal: Cancer Research
Cancer Res (1995) 55 (21): 4870–4874.
Published: 01 November 1995
View articletitled, Chemoprevention by Dehydroepiandrosterone and Indomethacin in a Rat Multiorgan Carcinogenesis Model
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Journal Articles

Increased Risk of Mammary Carcinoma Development following Transplacental and Trans-Breast Milk Exposure to a Food-derived Carcinogen, 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), in Sprague-Dawley Rats

Free
Ryohei Hasegawa, Juki Kimura, Makoto Yaono, Satoru Takahashi, Toshio Kato, Mitsuru Futakuchi, Masato Fukutake, Kazuo Fukutome, Keiji Wakabayashi, Takashi Sugimura, Nobuyuki Ito, Tomoyuki Shirai
Journal: Cancer Research
Cancer Res (1995) 55 (19): 4333–4338.
Published: 01 October 1995
View articletitled, Increased Risk of Mammary Carcinoma Development following Transplacental and Trans-Breast Milk Exposure to a Food-derived Carcinogen, 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), in Sprague-Dawley Rats
Open the PDF for Increased Risk of Mammary Carcinoma Development following Transplacental and Trans-Breast Milk Exposure to a Food-derived Carcinogen, 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), in Sprague-Dawley Rats in another window
Journal Articles

Carcinogenicity of Uracil, a Nongenotoxic Chemical, in Rats and Mice and Its Rationale

Free
Shoji Fukushima, Hikaru Tanaka, Emiko Asakawa, Masataka Kagawa, Atsushi Yamamoto, Tomoyuki Shirai
Journal: Cancer Research
Cancer Res (1992) 52 (7): 1675–1680.
Published: 01 April 1992
View articletitled, Carcinogenicity of Uracil, a Nongenotoxic Chemical, in Rats and Mice and Its Rationale
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Journal Articles

Forestomach and Kidney Carcinogenicity of Caffeic Acid in F344 Rats and C57BL/6N × C3H/HeN F1 Mice

Free
Akihiro Hagiwara, Masao Hirose, Satoru Takahashi, Kumiko Ogawa, Tomoyuki Shirai, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1991) 51 (20): 5655–5660.
Published: 01 October 1991
View articletitled, Forestomach and Kidney Carcinogenicity of Caffeic Acid in F344 Rats and C57BL/6N × C3H/HeN F1 Mice
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Journal Articles

Induction of Invasive Carcinomas in the Accessory Sex Organs Other Than the Ventral Prostate of Rats Given 3,2′-Dimethyl-4-aminobiphenyl and Testosterone Propionate

Free
Tomoyuki Shirai, Seiko Tamano, Toshio Kato, Shogo Iwasaki, Satoru Takahashi, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1991) 51 (4): 1264–1269.
Published: 01 February 1991
View articletitled, Induction of Invasive Carcinomas in the Accessory Sex Organs Other Than the Ventral Prostate of Rats Given 3,2′-Dimethyl-4-aminobiphenyl and Testosterone Propionate
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Journal Articles

Synergism by Sodium l-Ascorbate but Inhibition by l-Ascorbic Acid for Sodium Saccharin Promotion of Rat Two-Stage Bladder Carcinogenesis1

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Shoji Fukushima, Satoshi Uwagawa, Tomoyuki Shirai, Ryohei Hasegawa, Kumiko Ogawa
Journal: Cancer Research
Cancer Res (1990) 50 (14): 4195–4198.
Published: 01 July 1990
View articletitled, Synergism by Sodium l-Ascorbate but Inhibition by l-Ascorbic Acid for Sodium Saccharin Promotion of Rat Two-Stage Bladder Carcinogenesis1
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Journal Articles

Contribution of Aflatoxin B1 and Hepatitis B Virus Infection in the Induction of Liver Tumors in Ducks

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Lucyna Cova, Christopher P. Wild, Raj Mehrotra, Vladimir Turusov, Tomoyuki Shirai, Véronique Lambert, Chantal Jacquet, Lorenzo Tomatis, Christian Trépo, Ruggero Montesano
Journal: Cancer Research
Cancer Res (1990) 50 (7): 2156–2163.
Published: 01 April 1990
View articletitled, Contribution of Aflatoxin B1 and Hepatitis B Virus Infection in the Induction of Liver Tumors in Ducks
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Journal Articles

Cell Proliferation Induced by Uracil-Calculi and Subsequent Development of Reversible Papillomatosis in the Rat Urinary Bladder

Free
Tomoyuki Shirai, Shoji Fukushima, Yoshiaki Tagawa, Masanao Okumura, Nobuyuki Ito
Journal: Cancer Research
Cancer Res (1989) 49 (2): 378–383.
Published: 01 January 1989
View articletitled, Cell Proliferation Induced by Uracil-Calculi and Subsequent Development of Reversible Papillomatosis in the Rat Urinary Bladder
Open the PDF for Cell Proliferation Induced by Uracil-Calculi and Subsequent Development of Reversible Papillomatosis in the Rat Urinary Bladder in another window