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Tomoko Oh-hara
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Journal Articles

Abstract LB-123: Identification of the molecular mechanisms of resistance to NTRK inhibitors and the potential therapeutic strategies in NTRK1-rearranged cancers

Ryohei Katayama, Miho J. Fuse, Tomoko Oh-hara, Hayato Ogura, Naoya Fujita
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-123.
https://doi.org/10.1158/1538-7445.AM2017-LB-123
Published: 01 July 2017
View articletitled, Abstract LB-123: Identification of the molecular mechanisms of resistance to NTRK inhibitors and the potential therapeutic strategies in NTRK1-rearranged cancers
Journal Articles

Abstract B42: Platelets promote tumor growth and metastasis via direct interaction between Aggrus/podoplanin and CLEC-2

Satoshi Takagi, Shigeo Sato, Tomoko Oh-hara, Miho Takami, Sumie Koike, Naoya Fujita
Journal: Cancer Research
Cancer Res (2015) 75 (1_Supplement): B42.
https://doi.org/10.1158/1538-7445.CHTME14-B42
Published: 12 January 2015
View articletitled, Abstract B42: Platelets promote tumor growth and metastasis via direct interaction between Aggrus/podoplanin and CLEC-2
Journal Articles

Cytotoxic Activity of Tivantinib (ARQ 197) Is Not Due Solely to c-MET Inhibition

Ryohei Katayama, Aki Aoyama, Takao Yamori, Jie Qi, Tomoko Oh-hara, Youngchul Song, Jeffrey A. Engelman, Naoya Fujita
Journal: Cancer Research
Cancer Res (2013) 73 (10): 3087–3096.
https://doi.org/10.1158/0008-5472.CAN-12-3256
Published: 12 May 2013
View articletitled, Cytotoxic Activity of Tivantinib (ARQ 197) Is Not Due Solely to c-MET Inhibition
Open the PDF for Cytotoxic Activity of Tivantinib (ARQ 197) Is Not Due Solely to c-MET Inhibition in another window
Includes: Supplementary data
Journal Articles

Casein Kinase 2–Interacting Protein-1, a Novel Akt Pleckstrin Homology Domain-Interacting Protein, Down-regulates PI3K/Akt Signaling and Suppresses Tumor Growth In vivo

Emi Tokuda, Naoya Fujita, Tomoko Oh-hara, Shigeo Sato, Atsuo Kurata, Ryohei Katayama, Toshiki Itoh, Tadaomi Takenawa, Kohei Miyazono, Takashi Tsuruo
Journal: Cancer Research
Cancer Res (2007) 67 (20): 9666–9676.
https://doi.org/10.1158/0008-5472.CAN-07-1050
Published: 17 October 2007
View articletitled, Casein Kinase 2–Interacting Protein-1, a Novel Akt Pleckstrin Homology Domain-Interacting Protein, Down-regulates PI3K/Akt Signaling and Suppresses Tumor Growth In vivo
Open the PDF for Casein Kinase 2–Interacting Protein-1, a Novel Akt Pleckstrin Homology Domain-Interacting Protein, Down-regulates PI3K/Akt Signaling and Suppresses Tumor Growth In vivo in another window
Includes: Supplementary data
Journal Articles

Predominant Suppression of Apoptosome by Inhibitor of Apoptosis Protein in Non-Small Cell Lung Cancer H460 Cells: Therapeutic Effect of a Novel Polyarginine-conjugated Smac Peptide

Liling Yang, Tetsuo Mashima, Shigeo Sato, Mikiko Mochizuki, Hiroshi Sakamoto, Takao Yamori, Tomoko Oh-hara, Takashi Tsuruo
Journal: Cancer Research
Cancer Res (2003) 63 (4): 831–837.
Published: 15 February 2003
View articletitled, Predominant Suppression of Apoptosome by Inhibitor of Apoptosis Protein in Non-Small Cell Lung Cancer H460 Cells: Therapeutic Effect of a Novel Polyarginine-conjugated Smac Peptide
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Journal Articles

Blocking Telomerase by Dietary Polyphenols Is a Major Mechanism for Limiting the Growth of Human Cancer Cells in Vitro and in Vivo

Imad Naasani, Fujiko Oh-hashi, Tomoko Oh-hara, Wan Yong Feng, Jeffrey Johnston, Kenneth Chan, Takashi Tsuruo
Journal: Cancer Research
Cancer Res (2003) 63 (4): 824–830.
Published: 15 February 2003
View articletitled, Blocking Telomerase by Dietary Polyphenols Is a Major Mechanism for Limiting the Growth of Human Cancer Cells in Vitro and in Vivo
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Journal Articles

Antitumor Activity of a Novel Podophyllotoxin Derivative (TOP-53) against Lung Cancer and Lung Metastatic Cancer

Teruhiro Utsugi, Jiro Shibata, Yoshikazu Sugimoto, Kumio Aoyagi, Konstanty Wierzba, Takashi Kobunai, Tadafumi Terada, Tomoko Oh-hara, Takashi Tsuruo, Yuji Yamada
Journal: Cancer Research
Cancer Res (1996) 56 (12): 2809–2814.
Published: 01 June 1996
View articletitled, Antitumor Activity of a Novel Podophyllotoxin Derivative (TOP-53) against Lung Cancer and Lung Metastatic Cancer
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Journal Articles

Inhibitory Effects of Tumor Invasion-inhibiting Factor 2 and Its Conjugate on Disseminating Tumor Cells

Atsushi Isoai, Hiroko Goto-Tsukamoto, Takao Yamori, Tomoko Oh-hara, Takashi Tsuruo, Steve Silletti, Avraham Raz, Hideomi Watanabe, Hitoshi Akedo, Hiromichi Kumagai
Journal: Cancer Research
Cancer Res (1994) 54 (5): 1264–1270.
Published: 01 March 1994
View articletitled, Inhibitory Effects of Tumor Invasion-inhibiting Factor 2 and Its Conjugate on Disseminating Tumor Cells
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Journal Articles

Suppression of Experimental Lung Colonization of a Metastatic Variant of Murine Colon Adenocarcinoma 26 by a Monoclonal Antibody 8F11 Inhibiting Tumor Cell-induced Platelet Aggregation

Yoshikazu Sugimoto, Masahiko Watanabe, Tomoko Oh-hara, Shigeo Sato, Toshiyuki Isoe, Takashi Tsuruo
Journal: Cancer Research
Cancer Res (1991) 51 (3): 921–925.
Published: 01 February 1991
View articletitled, Suppression of Experimental Lung Colonization of a Metastatic Variant of Murine Colon Adenocarcinoma 26 by a Monoclonal Antibody 8F11 Inhibiting Tumor Cell-induced Platelet Aggregation
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Journal Articles

Elevated Expression of DNA Topoisomerase II in Camptothecin-resistant Human Tumor Cell Lines

Yoshikazu Sugimoto, Satomi Tsukahara, Tomoko Oh-hara, Leroy F. Liu, Takashi Tsuruo
Journal: Cancer Research
Cancer Res (1990) 50 (24): 7962–7965.
Published: 01 December 1990
View articletitled, Elevated Expression of DNA Topoisomerase II in Camptothecin-resistant Human Tumor Cell Lines
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Journal Articles

Decreased Expression of DNA Topoisomerase I in Camptothecin-resistant Tumor Cell Lines as Determined by a Monoclonal Antibody

Yoshikazu Sugimoto, Satomi Tsukahara, Tomoko Oh-hara, Toshiyuki Isoe, Takashi Tsuruo
Journal: Cancer Research
Cancer Res (1990) 50 (21): 6925–6930.
Published: 01 November 1990
View articletitled, Decreased Expression of DNA Topoisomerase I in Camptothecin-resistant Tumor Cell Lines as Determined by a Monoclonal Antibody
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Journal Articles

Mr 85,000 Membrane Protein Specifically Expressed in Adriamycin-resistant Human Tumor Cells

Hirofumi Hamada, Etsuko Okochi, Masahiko Watanabe, Tomoko Oh-hara, Yoshikazu Sugimoto, Hironori Kawabata, Takashi Tsuruo
Journal: Cancer Research
Cancer Res (1988) 48 (24_Part_1): 7082–7087.
Published: 15 December 1988
View articletitled, Mr 85,000 Membrane Protein Specifically Expressed in Adriamycin-resistant Human Tumor Cells
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Journal Articles

Purification of the Mr 22,000 Calcium-binding Protein (Sorcin) Associated with Multidrug Resistance and Its Detection with Monoclonal Antibodies

Hirofumi Hamada, Etsuko Okochi, Tomoko Oh-hara, Takashi Tsuruo
Journal: Cancer Research
Cancer Res (1988) 48 (11): 3173–3178.
Published: 01 June 1988
View articletitled, Purification of the Mr 22,000 Calcium-binding Protein (Sorcin) Associated with Multidrug Resistance and Its Detection with Monoclonal Antibodies
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Journal Articles

Acquisition of Metastatic Ability in Hybridomas between Two Low Metastatic Clones of Murine Colon Adenocarcinoma 26 Defective in Either Platelet-aggregating Activity or in Vivo Growth Potential

Yoshikazu Sugimoto, Tomoko Oh-hara, Masahiko Watanabe, Harumi Saito, Takao Yamori, Takashi Tsuruo
Journal: Cancer Research
Cancer Res (1987) 47 (16): 4396–4401.
Published: 01 August 1987
View articletitled, Acquisition of Metastatic Ability in Hybridomas between Two Low Metastatic Clones of Murine Colon Adenocarcinoma 26 Defective in Either Platelet-aggregating Activity or in Vivo Growth Potential
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Journal Articles

Rhizoxin, a Macrocyclic Lactone Antibiotic, as a New Antitumor Agent against Human and Murine Tumor Cells and Their Vincristine-resistant Sublines

Takashi Tsuruo, Tomoko Oh-hara, Harumi Iida, Shigeru Tsukagoshi, Zenji Sato, Izumi Matsuda, Shigeo Iwasaki, Shigenobu Okuda, Fusaaki Shimizu, Kazuhiko Sasagawa, Masaharu Fukami, Kuniaki Fukuda, Masao Arakawa
Journal: Cancer Research
Cancer Res (1986) 46 (1): 381–385.
Published: 01 January 1986
View articletitled, Rhizoxin, a Macrocyclic Lactone Antibiotic, as a New Antitumor Agent against Human and Murine Tumor Cells and Their Vincristine-resistant Sublines
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