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Myeloid Cells Induce Infiltration and Activation of B Cells and CD4⁺ T Follicular Helper Cells to Sensitize Brain Metastases to Combination Immunotherapy

Toshifumi Ninomiya, Naoya Kemmotsu, Fumiaki Mukohara, Masaki Magari, Ai Miyamoto, Youki Ueda, Takamasa Ishino, Joji Nagasaki, Tomohiro Fujiwara, Hidetaka Yamamoto, Hidetoshi Hayashi, Kota Tachibana, Joji Ishida, Yoshihiro Otani, Shota Tanaka, Shinichi Toyooka, Isamu Okamoto, Yosuke Togashi

Cancer Res (2025) 85 (6): 1082–1096.

https://doi.org/10.1158/0008-5472.CAN-24-2274

Published: 14 March 2025

View articletitled, Myeloid Cells Induce Infiltration and Activation of B Cells and CD4+ T Follicular Helper Cells to Sensitize Brain Metastases to Combination Immunotherapy

Includes: Supplementary data

Journal Articles

Abstract 5649: PRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumors

Shota Takihira, Eiji Nakata, Daisuke Yamada, Tatsunori Osone, Tomoka Takao, Takeshi Takarada, Akira Hirasawa, Takuto Itano, Tomohiro Fujiwara, Toshiyuki Kunisada, Toshifumi Ozaki

Cancer Res (2024) 84 (6_Supplement): 5649.

https://doi.org/10.1158/1538-7445.AM2024-5649

Published: 22 March 2024

View articletitled, Abstract 5649: PRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumors

Journal Articles

Abstract 6456: The utility of clinical sequencing in the diagnosis and treatment of soft tissue sarcomas; Real world data based on nation-wide database

Eiji Nakada, Tomohiro Fujiwara, Toshi Kunisada, Shota Takihira, Daisuke Ennishi, Hideki Yamamoto, Kiichiro Ninomiya, Shuta Tomida, Mashu Futagawa, Akira Hirasawa, Shinichi Toyooka, Toshifumi Ozaki

Cancer Res (2024) 84 (6_Supplement): 6456.

https://doi.org/10.1158/1538-7445.AM2024-6456

Published: 22 March 2024

View articletitled, Abstract 6456: The utility of clinical sequencing in the diagnosis and treatment of soft tissue sarcomas; Real world data based on nation-wide database

Journal Articles

Abstract 5188: Molecular radiosensitization in soft tissue sarcomas by telomerase-specific oncolytic adenovirus

Tadashi Komatsubara, Toshinori Omori, Hiroshi Tazawa, Kazuhisa Sugiu, Yusuke Mochizuki, Yasuaki Yamakawa, Shuhei Osaki, Joe Hasei, Tomohiro Fujiwara, Toshiyuki Kunisada, Yasuo Urata, Tsoshifumi Ozaki, Toshiyoshi Fujiwara

Cancer Res (2017) 77 (13_Supplement): 5188.

https://doi.org/10.1158/1538-7445.AM2017-5188

Published: 01 July 2017

View articletitled, Abstract 5188: Molecular radiosensitization in soft tissue sarcomas by telomerase-specific oncolytic adenovirus

Journal Articles

Abstract 969: Circulating cell-free microRNA as a novel biomarker for synovial sarcoma patients

Koji Uotani, Tomohiro Fujiwara, Aki Yoshida, Takuya Morita, Yutaka Nezu, Tadashi Komatsubara, Kazuhisa Sugiu, Takenori Uehara, Toshinori Omari, Ken Takeda, Toshiyuki Kunisada, Junya Toguchida, Akira Kawai, Takahiro Ochiya, Toshifumi Ozaki

Cancer Res (2016) 76 (14_Supplement): 969.

https://doi.org/10.1158/1538-7445.AM2016-969

Published: 15 July 2016

View articletitled, Abstract 969: Circulating cell-free microRNA as a novel biomarker for synovial sarcoma patients

Journal Articles

Abstract 1963: Characterization of microRNA profilings in tumor tissues and serum from myxofibrosarcoma patients

Takuya Morita, Tomohiro Fujiwara, Koji Uotani, Aki Yoshida, Toshihumi Ozaki, Tsukuda Kazunori

Cancer Res (2016) 76 (14_Supplement): 1963.

https://doi.org/10.1158/1538-7445.AM2016-1963

Published: 15 July 2016

View articletitled, Abstract 1963: Characterization of microRNA profilings in tumor tissues and serum from myxofibrosarcoma patients

Journal Articles

Abstract 455: Identification of exosomal surface marker derived from Ewing sarcoma cells

Aki Yoshida, Tomohiro Fujiwara, Koji Uotani, Yusuke Yoshioka, Koji Ueda, Takuya Morita, Ken Takeda, Toshiyuki Kunisada, Yutaka Nezu, Hiroyuki Kawashima, Takahiro Ochiya, Toshifumi Ozaki

Cancer Res (2016) 76 (14_Supplement): 455.

https://doi.org/10.1158/1538-7445.AM2016-455

Published: 15 July 2016

View articletitled, Abstract 455: Identification of exosomal surface marker derived from Ewing sarcoma cells

Journal Articles

Abstract 456: Identification of circulating tumor-derived microRNA signatures in osteosarcoma

Tomohiro Fujiwara, Koji Uotani, Aki Yoshida, Takuya Morita, Tadashi Komatsubara, Kazuhisa Sugiu, Toshinori Omori, Ken Takeda, Toshiyuki Kunisada, Yutaka Nezu, Akira Kawai, Hirotaka Kanzaki, Takahiro Ochiya, Toshifumi Ozaki

Cancer Res (2016) 76 (14_Supplement): 456.

https://doi.org/10.1158/1538-7445.AM2016-456

Published: 15 July 2016

View articletitled, Abstract 456: Identification of circulating tumor-derived microRNA signatures in osteosarcoma

Journal Articles

Abstract 4677: Tumor suppressor p53 reactivation by oncolytic adenovirus reverses chemoresistance in human osteosarcomas

Kazuhisa Sugiu, Hiroshi Tazawa, Joe Hasei, Shuhei Osaki, Yasuaki Yamakawa, Toshinori Omori, Tadashi Komatsubara, Kouji Uotani, Tomohiro Fujiwara, Toshiyuki Kunisada, Yasuo Urata, Toshifumi Ozaki, Toshiyoshi Fujiwara

Cancer Res (2016) 76 (14_Supplement): 4677.

https://doi.org/10.1158/1538-7445.AM2016-4677

Published: 15 July 2016

View articletitled, Abstract 4677: Tumor suppressor p53 reactivation by oncolytic adenovirus reverses chemoresistance in human osteosarcomas

Journal Articles

Abstract 1794: Preclinical evaluation of radiotherapy in combination with radio-sensitizing telomerase-specific oncolytic virus for human bone and soft tissue sarcomas

Toshinori Omori, Yasuaki Yamakawa, Joe Hasei, Hiroshi Tazawa, Shuhei Osaki, Tusyoshi Sasaki, Kazuhisa Sugiu, Tomohiro Fujiwara, Toshiyuki Kunisada, Yasuo Urata, Toshifumi Ozaki, Toshiyoshi Fujiwara

Cancer Res (2015) 75 (15_Supplement): 1794.

https://doi.org/10.1158/1538-7445.AM2015-1794

Published: 01 August 2015

View articletitled, Abstract 1794: Preclinical evaluation of radiotherapy in combination with radio-sensitizing telomerase-specific oncolytic virus for human bone and soft tissue sarcomas

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Myeloid Cells Induce Infiltration and Activation of B Cells and CD4⁺ T Follicular Helper Cells to Sensitize Brain Metastases to Combination Immunotherapy

Abstract 5649: PRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumors

Abstract 6456: The utility of clinical sequencing in the diagnosis and treatment of soft tissue sarcomas; Real world data based on nation-wide database

Abstract 5188: Molecular radiosensitization in soft tissue sarcomas by telomerase-specific oncolytic adenovirus

Abstract 969: Circulating cell-free microRNA as a novel biomarker for synovial sarcoma patients

Abstract 1963: Characterization of microRNA profilings in tumor tissues and serum from myxofibrosarcoma patients

Abstract 455: Identification of exosomal surface marker derived from Ewing sarcoma cells

Abstract 456: Identification of circulating tumor-derived microRNA signatures in osteosarcoma

Abstract 4677: Tumor suppressor p53 reactivation by oncolytic adenovirus reverses chemoresistance in human osteosarcomas

Abstract 1794: Preclinical evaluation of radiotherapy in combination with radio-sensitizing telomerase-specific oncolytic virus for human bone and soft tissue sarcomas

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