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Journal Articles

Abstract 1334: Chemotherapy regulated microRNA-125/HER2 pathway as a novel therapeutic target for trastuzumab-mediated cellular cytotoxicity in small-cell lung cancer

Shigehiro Yagishita, Yu Fujita, Yuichi Fujimoto, Fumiyuki Takahashi, Kazuhisa Takahashi, Tomohide Tamura, Fumiaki Koizumi

Cancer Res (2015) 75 (15_Supplement): 1334.

DOI: https://doi.org/10.1158/1538-7445.AM2015-1334

Published: 01 August 2015

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Journal Articles

Abstract 1605: Dielectrophoretic microwell array system for detection circulating tumor cells in patients with solid tumors and single cell analysis of detected circulating tumor cells

Takeshi Sawada, Atsushi Morimoto, Tatsu Shimoyama, Toshinari Yamashita, Toshifumi Mogami, Kazuki Iijima, Mayu Yunokawa, Shintaro Kanda, Yasuyuki Akiyama, Koji Katayama, Masaru Watanabe, Yasuhiro Koh, Kenji Tamura, Tomohide Tamura, Toru Futami, Fumiaki Koizumi

Cancer Res (2015) 75 (15_Supplement): 1605.

DOI: https://doi.org/10.1158/1538-7445.AM2015-1605

Published: 01 August 2015

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Journal Articles

Abstract 1445: Clinical feasibility study of a novel cytometry-based-system for the detection of circulating tumor cells of patients with lung cancer.

Takeshi Sawada, Yukiko Ito, Masaru Watanabe, Yuu Fujimura, Shinji Nakamichi, Shintaro Kanda, Hidehito Horinouchi, Yutaka Fujiwara, Hiroshi Nokihara, Noboru Yamamoto, Tomohide Tamura, Yasuhiro Koh, Fumiaki Koizumi

Cancer Res (2013) 73 (8_Supplement): 1445.

DOI: https://doi.org/10.1158/1538-7445.AM2013-1445

Published: 15 April 2013

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Journal Articles

Abstract 2527: Antibody-dependent cellular cytotoxicity of cetuximab against colorectal cancer cells with wild-type and mutant KRAS

Yusuke Nakadate, Yuka Kitamura, Tomohide Tamura, Fumiaki Koizumi

Cancer Res (2012) 72 (8_Supplement): 2527.

DOI: https://doi.org/10.1158/1538-7445.AM2012-2527

Published: 15 April 2012

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Journal Articles

Abstract 1567: The multi-targeted kinase inhibitor Sunitinib blocks VEGF-C signaling pathway and lymphangiogenesis

Kodera Yasuo, Yasufumi Katanasaka, Yuuka Kitamura, Tomohide Tamura, Fumiaki Koizumi

Cancer Res (2010) 70 (8_Supplement): 1567.

DOI: https://doi.org/10.1158/1538-7445.AM10-1567

Published: 15 April 2010

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Journal Articles

Abstract 2747: Prediction of neutropenia in patients with solid tumor by population pharmacokinetics / pharmacodynamics analyses for the different formulations of paclitaxel

Hironobu Minami, Tomohide Tamura, Yasuhiro Fujiwara, Yasutsuna Sasaki, Hidetoshi Yamaya, Katsuhiro Ono

Cancer Res (2010) 70 (8_Supplement): 2747.

DOI: https://doi.org/10.1158/1538-7445.AM10-2747

Published: 15 April 2010

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Journal Articles

mTOR Signal and Hypoxia-Inducible Factor-1α Regulate CD133 Expression in Cancer Cells

Kazuko Matsumoto, Tokuzo Arao, Kaoru Tanaka, Hiroyasu Kaneda, Kanae Kudo, Yoshihiko Fujita, Daisuke Tamura, Keiichi Aomatsu, Tomohide Tamura, Yasuhide Yamada, Nagahiro Saijo, Kazuto Nishio

Cancer Res (2009) 69 (18): 7160–7164.

DOI: https://doi.org/10.1158/0008-5472.CAN-09-1289

Published: 14 September 2009

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Includes: Supplementary data

Journal Articles

Abstract #696: Circulating endothelial cells in non-small cell lung cancer patients treated with carboplatin and paclitaxel

Shintaro Kanda, Kazuhiko Yamada, Yutaka Fujiwara, Hiroshi Nokihara, Noboru Yamamoto, Ikuo Sekine, Hideo Kunitoh, Yuichiro Ohe, Takeshi Watabe, Yuji Shimoda, Tomohide Tamura, Fumiaki Koizumi

Cancer Res (2009) 69 (9_Supplement): 696.

Published: 01 May 2009

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Journal Articles

Abstract #5440: Pharmacokinetics of ABI-007, cremophor-free nanoparticle formulation of paclitaxel, in Japanese and Chinese patients with malignancies

Cancer Res (2009) 69 (9_Supplement): 5440.

Published: 01 May 2009

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Journal Articles

Pertuzumab, a novel HER dimerization inhibitor, inhibits the growth of human NSCLC cells mediated by the HER3 signaling pathway

Kazuko Sakai, Hideyuki Yokote, Tomohide Tamura, Nagahiro Saijo, Kazuto Nishio

Cancer Res (2006) 66 (8_Supplement): 356.

Published: 15 April 2006

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Journal Articles

AZD2171 shows potent anti-tumor activity against gastric cancer expressing variant K-SAM/FGFR2

Masayuki Takeda, Tokuzo Arao, Hideyuki Yokote, Kazuko Sakai, Hideharu Kimura, Kazuyoshi Yanagihara, Hiroki Sasaki, Tomohide Tamura, Nagahiro Saijo, Kazuto Nishio

Cancer Res (2006) 66 (8_Supplement): 890.

Published: 15 April 2006

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Journal Articles

Detection of epidermal growth factor receptor mutations in pleural effusion from non-small cell lung cancer patients

Hideharu Kimura, Yutaka Fujiwara, Makoto Kawaishi, Tomohide Tamura, Kazuo Kasahara, Kazuto Nishio

Cancer Res (2006) 66 (8_Supplement): 1064.

Published: 15 April 2006

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Journal Articles

Deletional mutant EGFR detected in circulating tumor-derived DNA from lung cancer patients treated with gefitinib.

Hideharu Kimura, Hisao Fukumoto, Sarah Park, Hideo Kunito, Tomohide Tamura, Kazuo Kasahara, Kazuto Nishio

Cancer Res (2005) 65 (9_Supplement): 112.

Published: 01 May 2005

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Journal Articles

A new biomarker for skin rash in Japanese NSCLC patients treated with first line monotherapy of gefitinib.

Takashi Sone, Hideharu Kimura, Akihiro Yoshimoto, Masaru Sekishima, Tomohide Tamura, Kazuto Nishio, Kazuo Kasahara

Cancer Res (2005) 65 (9_Supplement): 116.

Published: 01 May 2005

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Journal Articles

Gene expression analysis to identify the pharmacodynamic effects of docetaxel on the Rho signal pathway in human lung cancer patients

Tatsu Shimoyama, Noboru Yamamoto, Tetsutarou Hamano, Tomohide Tamura, Kazuto Nishio

Cancer Res (2005) 65 (9_Supplement): 977.

Published: 01 May 2005

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Journal Articles

Small In-Frame Deletion in the Epidermal Growth Factor Receptor as a Target for ZD6474

Tokuzo Arao, Hisao Fukumoto, Masayuki Takeda, Tomohide Tamura, Nagahiro Saijo, Kazuto Nishio

Cancer Res (2004) 64 (24): 9101–9104.

DOI: https://doi.org/10.1158/0008-5472.CAN-04-2360

Published: 16 December 2004

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Journal Articles

Schedule-dependent interactions between the EGFR tyrosine kinase inhibitor gefitinib (‘Iressa’, ZD1839) and the DNA topoisomerase I inhibitor SN-38 in human lung cancer cells

Tatsu Shimoyama, Fumiaki Koizumi, Sonke Korfee, Tomohide Tamura, Nagahiro Saijo, Kazuto Nishio

Cancer Res (2004) 64 (7_Supplement): 1048.

Published: 01 April 2004

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Journal Articles

Unpredicted Clinical Pharmacology of UCN-01 Caused by Specific Binding to Human α₁-Acid Glycoprotein

Eiichi Fuse, Hiromi Tanii, Noriaki Kurata, Hiroyuki Kobayashi, Yasuhiro Shimada, Tomohide Tamura, Yasutsuna Sasaki, Yusuke Tanigawara, Richard D. Lush, Donna Headlee, William D. Figg, Susan G. Arbuck, Adrian M. Senderowicz, Edward A. Sausville, Shiro Akinaga, Takashi Kuwabara, Satoshi Kobayashi

Cancer Res (1998) 58 (15): 3248–3253.

Published: 01 August 1998

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Journal Articles

Correlation of Therapeutic Outcome in Non-Small Cell Lung Cancer and DNA Damage Assayed by Polymerase Chain Reaction in Leukocytes Damaged in Vitro

Fumihiro Oshita, Nobuyuki Yamamoto, Minoru Fukuda, Yuichiro Ohe, Tomohide Tamura, Kenji Eguchi, Tetsu Shinkai, Nagahiro Saijo

Cancer Res (1995) 55 (11): 2334–2337.

Published: 01 June 1995

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Journal Articles

Phase I Clinical Trial of Irinotecan (CPT-11), 7-Ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin, and Cisplatin in Combination with Fixed Dose of Vindesine in Advanced Non-Small Cell Lung Cancer

Tetsu Shinkai, Hitoshi Arioka, Hiroshi Kunikane, Kenji Eguchi, Yasutsuna Sasaki, Tomohide Tamura, Yuichiro Ohe, Fumihiro Oshita, Makoto Nishio, Atsuya Karato, Hiroaki Okamoto, Hajime Nakashima, Hironobu Ohmatsu, Junichi Shiraishi, Naohiro Nomura, Nagahiro Saijo

Cancer Res (1994) 54 (10): 2636–2642.

Published: 01 May 1994

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NARROW

Abstract 1334: Chemotherapy regulated microRNA-125/HER2 pathway as a novel therapeutic target for trastuzumab-mediated cellular cytotoxicity in small-cell lung cancer

Abstract 1605: Dielectrophoretic microwell array system for detection circulating tumor cells in patients with solid tumors and single cell analysis of detected circulating tumor cells

Abstract 1445: Clinical feasibility study of a novel cytometry-based-system for the detection of circulating tumor cells of patients with lung cancer.

Abstract 2527: Antibody-dependent cellular cytotoxicity of cetuximab against colorectal cancer cells with wild-type and mutant KRAS

Abstract 1567: The multi-targeted kinase inhibitor Sunitinib blocks VEGF-C signaling pathway and lymphangiogenesis

Abstract 2747: Prediction of neutropenia in patients with solid tumor by population pharmacokinetics / pharmacodynamics analyses for the different formulations of paclitaxel

mTOR Signal and Hypoxia-Inducible Factor-1α Regulate CD133 Expression in Cancer Cells

Abstract #696: Circulating endothelial cells in non-small cell lung cancer patients treated with carboplatin and paclitaxel

Abstract #5440: Pharmacokinetics of ABI-007, cremophor-free nanoparticle formulation of paclitaxel, in Japanese and Chinese patients with malignancies

Pertuzumab, a novel HER dimerization inhibitor, inhibits the growth of human NSCLC cells mediated by the HER3 signaling pathway

AZD2171 shows potent anti-tumor activity against gastric cancer expressing variant K-SAM/FGFR2

Detection of epidermal growth factor receptor mutations in pleural effusion from non-small cell lung cancer patients

Deletional mutant EGFR detected in circulating tumor-derived DNA from lung cancer patients treated with gefitinib.

A new biomarker for skin rash in Japanese NSCLC patients treated with first line monotherapy of gefitinib.

Gene expression analysis to identify the pharmacodynamic effects of docetaxel on the Rho signal pathway in human lung cancer patients

Small In-Frame Deletion in the Epidermal Growth Factor Receptor as a Target for ZD6474

Schedule-dependent interactions between the EGFR tyrosine kinase inhibitor gefitinib (‘Iressa’, ZD1839) and the DNA topoisomerase I inhibitor SN-38 in human lung cancer cells

Unpredicted Clinical Pharmacology of UCN-01 Caused by Specific Binding to Human α₁-Acid Glycoprotein

Correlation of Therapeutic Outcome in Non-Small Cell Lung Cancer and DNA Damage Assayed by Polymerase Chain Reaction in Leukocytes Damaged in Vitro

Phase I Clinical Trial of Irinotecan (CPT-11), 7-Ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin, and Cisplatin in Combination with Fixed Dose of Vindesine in Advanced Non-Small Cell Lung Cancer

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