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Tom van Wezel
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Journal Articles

Functional Analysis Identifies Damaging CHEK2 Missense Variants Associated with Increased Cancer Risk

Rick A.C.M. Boonen, Wouter W. Wiegant, Nandi Celosse, Bas Vroling, Stephan Heijl, Zsofia Kote-Jarai, Martina Mijuskovic, Simona Cristea, Nienke Solleveld-Westerink, Tom van Wezel, Niko Beerenwinkel, Rosalind Eeles, Peter Devilee, Maaike P.G. Vreeswijk, Giancarlo Marra, Haico van Attikum
Journal: Cancer Research
Cancer Res (2022) 82 (4): 615–631.
https://doi.org/10.1158/0008-5472.CAN-21-1845
Published: 15 February 2022
View article titled, Functional Analysis Identifies Damaging <em>CHEK2</em> Missense Variants Associated with Increased Cancer Risk
Open the PDF for Functional Analysis Identifies Damaging <em>CHEK2</em> Missense Variants Associated with Increased Cancer Risk in another window
Includes: Supplementary data
Journal Articles

Abstract 3191: Detection of molecular drivers in inflammatory myofibroblastic tumor: study on archival tissue from EORTC 90101 “CREATE” phase II clinical trial

Agnieszka Wozniak, Che-Jui Lee, Tom van Wezel, Jozef Sufliarsky, Hans Gelderblom, Jean-Yves Blay, Maria Debiec-Rychter, Raf Sciot, Judith V.M.G. Bovee, Patrick Schöffski
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3191.
https://doi.org/10.1158/1538-7445.AM2020-3191
Published: 15 August 2020
View article titled, Abstract 3191: Detection of molecular drivers in inflammatory myofibroblastic tumor: study on archival tissue from EORTC 90101 “CREATE” phase II clinical trial
Journal Articles

Abstract 649: Development of a novel RNA sequencing approach that identifies aberrant splicing in cancer predisposing genes

Anne M. Jansen, Heleen M. van der Klift, Jaap D. van Eendenburg, Carli M. Tops, Juul T. Wijnen, Frederik J. Hes, Ajay Goel, Hans Morreau, Tom van Wezel
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 649.
https://doi.org/10.1158/1538-7445.AM2018-649
Published: 01 July 2018
View article titled, Abstract 649: Development of a novel RNA sequencing approach that identifies aberrant splicing in cancer predisposing genes
Journal Articles

Abstract 4322: Kinase activity profiles distinguish papillary thyroid cancers with and without BRAF V600E mutations

Maria H. Hilhorst, Adrienne van den Berg, Tom van Wezel, Tim Kievits, Piet J. Boender, Rik de Wijn, Rob Ruijtenbeek, Wim Corver, Hans Morreau
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4322.
https://doi.org/10.1158/1538-7445.AM2015-4322
Published: 01 August 2015
View article titled, Abstract 4322: Kinase activity profiles distinguish papillary thyroid cancers with and without BRAF V600E mutations
Journal Articles

Kinome Profiling of Chondrosarcoma Reveals Src-Pathway Activity and Dasatinib as Option for Treatment

Yvonne M. Schrage, Inge H. Briaire-de Bruijn, Noel F.C.C. de Miranda, Jolieke van Oosterwijk, Antonie H.M. Taminiau, Tom van Wezel, Pancras C.W. Hogendoorn, Judith V.M.G. Bovée
Journal: Cancer Research
Cancer Res (2009) 69 (15): 6216–6222.
https://doi.org/10.1158/0008-5472.CAN-08-4801
Published: 29 July 2009
View article titled, Kinome Profiling of Chondrosarcoma Reveals Src-Pathway Activity and Dasatinib as Option for Treatment
Open the PDF for Kinome Profiling of Chondrosarcoma Reveals Src-Pathway Activity and Dasatinib as Option for Treatment in another window
Includes: Supplementary data
Journal Articles

Genome-wide Allelic State Analysis on Flow-Sorted Tumor Fractions Provides an Accurate Measure of Chromosomal Aberrations

Willem E. Corver, Anneke Middeldorp, Natalja T. ter Haar, Ekaterina S. Jordanova, Marjo van Puijenbroek, Ronald van Eijk, Cees J. Cornelisse, Gert Jan Fleuren, Hans Morreau, Jan Oosting, Tom van Wezel
Journal: Cancer Research
Cancer Res (2008) 68 (24): 10333–10340.
https://doi.org/10.1158/0008-5472.CAN-08-2665
Published: 15 December 2008
View article titled, Genome-wide Allelic State Analysis on Flow-Sorted Tumor Fractions Provides an Accurate Measure of Chromosomal Aberrations
Open the PDF for Genome-wide Allelic State Analysis on Flow-Sorted Tumor Fractions Provides an Accurate Measure of Chromosomal Aberrations in another window
Includes: Supplementary data
Journal Articles

Chromosomal instability in the progression from rectal adenoma to carcinoma identified by single nucleotide polymorphism arrays

Esther H. Lips, Ronald Van Eijk, Jan Oosting, Paul H C Eilers, Rob A E M Tollenaar, Cornelis J H Van de Velde, Cornelis F M Sier, Eelco J. De Graaf, Thomas M. Karsten, Tom Van Wezel, Hans Morreau
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 93.
Published: 15 April 2006
View article titled, Chromosomal instability in the progression from rectal adenoma to carcinoma identified by single nucleotide polymorphism arrays
Journal Articles

Reliable High-Throughput Genotyping and Loss-of-Heterozygosity Detection in Formalin-Fixed, Paraffin-Embedded Tumors Using Single Nucleotide Polymorphism Arrays

Esther H. Lips, Jan Willem F. Dierssen, Ronald van Eijk, Jan Oosting, Paul H.C. Eilers, Rob A.E.M. Tollenaar, Eelco J. de Graaf, Ruben van't Slot, Cisca Wijmenga, Hans Morreau, Tom van Wezel
Journal: Cancer Research
Cancer Res (2005) 65 (22): 10188–10191.
https://doi.org/10.1158/0008-5472.CAN-05-2486
Published: 15 November 2005
View article titled, Reliable High-Throughput Genotyping and Loss-of-Heterozygosity Detection in Formalin-Fixed, Paraffin-Embedded Tumors Using Single Nucleotide Polymorphism Arrays
Open the PDF for Reliable High-Throughput Genotyping and Loss-of-Heterozygosity Detection in Formalin-Fixed, Paraffin-Embedded Tumors Using Single Nucleotide Polymorphism Arrays in another window
Journal Articles

Four New Colon Cancer Susceptibility Loci, Scc6 to Scc9 in the Mouse

Tom van Wezel, Claudia A. L. Ruivenkamp, Alphons P. M. Stassen, Corina J. A. Moen, Peter Demant
Journal: Cancer Research
Cancer Res (1999) 59 (17): 4216–4218.
Published: 01 September 1999
View article titled, Four New Colon Cancer Susceptibility Loci, <em>Scc6</em> to <em>Scc9</em> in the Mouse
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