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Todd C. Skaar
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Journal Articles

Abstract 1875: Identifying genetic variants contributing to cellular susceptibility to tamoxifen using a genome-wide cell-based model

Free
Dana Ziliak, Liming Weng, Eric R. Gamazon, Hae Kyung Im, Zeruesenay Desta, Todd C. Skaar, David A. Flockhart, Rong Stephanie Huang
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1875.
https://doi.org/10.1158/1538-7445.AM2012-1875
Published: 15 April 2012
View articletitled, Abstract 1875: Identifying genetic variants contributing to cellular susceptibility to tamoxifen using a genome-wide cell-based model
Journal Articles

Abstract 3604: Significant effect of polymorphisms in CYP2D6 and DT-1 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients

Free
Hitoshi Zembutsu, Kazuma Kiyotani, Taisei Mushiroda, Chiyo K. Imamura, Naoya Hosono, Michiaki Kubo, Yusuke Tanigawara, David A. Flockhart, Todd C. Skaar, Zeruesenay Desta, Fuminori Aki, Koichi Hirata, Yuichi Takatsuka, Minoru Okazaki, Shozo Ohsumi, Takashi Yamakawa, Mitsunori Sasa, Yusuke Nakamura
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3604.
https://doi.org/10.1158/1538-7445.AM10-3604
Published: 15 April 2010
View articletitled, Abstract 3604: Significant effect of polymorphisms in CYP2D6 and DT-1 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients
Journal Articles

Diindolylmethane inhibits indoleamine 2,3-dioxygenase activity in breast cancer cells

Free
Donghua Cao, Bryan Ward, Zeruesenay Desta, Tonya Roberts, Sunil Badve, Robert Bigsby, David Wilkes, Todd C. Skaar
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 577.
Published: 01 May 2005
View articletitled, Diindolylmethane inhibits indoleamine 2,3-dioxygenase activity in breast cancer cells
Journal Articles

Interferon Regulatory Factor-1 Mediates the Proapoptotic but Not Cell Cycle Arrest Effects of the Steroidal Antiestrogen ICI 182,780 (Faslodex, Fulvestrant)

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Kerrie B. Bouker, Todd C. Skaar, David R. Fernandez, Kerry A. O’Brien, Rebecca B. Riggins, Donghua Cao, Robert Clarke
Journal: Cancer Research
Cancer Res (2004) 64 (11): 4030–4039.
https://doi.org/10.1158/0008-5472.CAN-03-3602
Published: 01 June 2004
View articletitled, Interferon Regulatory Factor-1 Mediates the Proapoptotic but Not Cell Cycle Arrest Effects of the Steroidal Antiestrogen ICI 182,780 (Faslodex, Fulvestrant)
Open the PDF for Interferon Regulatory Factor-1 Mediates the Proapoptotic but Not Cell Cycle Arrest Effects of the Steroidal Antiestrogen ICI 182,780 (Faslodex, Fulvestrant) in another window
Journal Articles

The gene expression profiles from a novel 9-cis-retinoic acid resistant MCF-7 variant can predict retinoid resistant/responsive phenotypes using computational bioinformatics

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Richard Y. Lee, Kerry A. O’Brien, Todd C. Skaar, Zhiping Gu, Zuyi Wang, Alan L. Zwart, Junying Zhang, Bassam R. Haddad, Yue Wang, Robert Clarke
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 341.
Published: 01 April 2004
View articletitled, The gene expression profiles from a novel 9-cis-retinoic acid resistant MCF-7 variant can predict retinoid resistant/responsive phenotypes using computational bioinformatics
Journal Articles

Endoxifen has antiestrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen.

Free
Youngchai Lim, Michael D. Johnson, Ross V. Weatherman, David A. Flockhart, Todd C. Skaar
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 867–868.
Published: 01 April 2004
View articletitled, Endoxifen has antiestrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifen.
Journal Articles

Association of Interferon Regulatory Factor-1, Nucleophosmin, Nuclear Factor-κB, and Cyclic AMP Response Element Binding with Acquired Resistance to Faslodex (ICI 182,780)

Available to Purchase
Zhiping Gu, Richard Y. Lee, Todd C. Skaar, Kerrie B. Bouker, James N. Welch, Jianping Lu, Aiyi Liu, Yuelin Zhu, Natalie Davis, Fabio Leonessa, Nils Brünner, Yue Wang, Robert Clarke
Journal: Cancer Research
Cancer Res (2002) 62 (12): 3428–3437.
Published: 01 June 2002
View articletitled, Association of Interferon Regulatory Factor-1, Nucleophosmin, Nuclear Factor-κB, and Cyclic AMP Response Element Binding with Acquired Resistance to Faslodex (ICI 182,780)
Open the PDF for Association of Interferon Regulatory Factor-1, Nucleophosmin, Nuclear Factor-κB, and Cyclic AMP Response Element Binding with Acquired Resistance to Faslodex (ICI 182,780) in another window
Journal Articles

MCF7/LCC9: An Antiestrogen-resistant MCF-7 Variant in Which Acquired Resistance to the Steroidal Antiestrogen ICI 182,780 Confers an Early Cross-Resistance to the Nonsteroidal Antiestrogen Tamoxifen

Available to Purchase
Nils Brünner, Birgitte Boysen, Stana Jirus, Todd C. Skaar, Claus Holst-Hansen, Jeremy Lippman, Thomas Frandsen, Mogens Spang-Thomsen, Suzanne A. W. Fuqua, Robert Clarke
Journal: Cancer Research
Cancer Res (1997) 57 (16): 3486–3493.
Published: 01 August 1997
View articletitled, MCF7/LCC9: An Antiestrogen-resistant MCF-7 Variant in Which Acquired Resistance to the Steroidal Antiestrogen ICI 182,780 Confers an Early Cross-Resistance to the Nonsteroidal Antiestrogen Tamoxifen
Open the PDF for MCF7/LCC9: An Antiestrogen-resistant MCF-7 Variant in Which Acquired Resistance to the Steroidal Antiestrogen ICI 182,780 Confers an Early Cross-Resistance to the Nonsteroidal Antiestrogen Tamoxifen in another window