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Timothy Nacarelli
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Journal Articles

Abstract 2628: Exploring synthetic lethality between VPS4A and VPS4B paralog enzymes in pancreatic and colon cancer

Timothy Nacarelli, Nelisa Bechtel, Yanzhe Gao, Kurt Auger
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2628.
https://doi.org/10.1158/1538-7445.AM2022-2628
Published: 15 June 2022
View article titled, Abstract 2628: Exploring synthetic lethality between VPS4A and VPS4B paralog enzymes in pancreatic and colon cancer
Journal Articles

Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers

Joseph A. Zundell, Takeshi Fukumoto, Jianhuang Lin, Nail Fatkhudinov, Timothy Nacarelli, Andrew V. Kossenkov, Qin Liu, Joel Cassel, Chih-Chi Andrew Hu, Shuai Wu, Rugang Zhang
Journal: Cancer Research
Cancer Res (2021) 81 (20): 5325–5335.
https://doi.org/10.1158/0008-5472.CAN-21-1545
Published: 15 October 2021
View article titled, Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <em>ARID1A</em>-Mutant Ovarian Cancers
Open the PDF for Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <em>ARID1A</em>-Mutant Ovarian Cancers in another window
Includes: Supplementary data
Journal Articles

NAMPT Inhibition Suppresses Cancer Stem-like Cells Associated with Therapy-Induced Senescence in Ovarian Cancer

Timothy Nacarelli, Takeshi Fukumoto, Joseph A. Zundell, Nail Fatkhutdinov, Stephanie Jean, Mark G. Cadungog, Mark E. Borowsky, Rugang Zhang
Journal: Cancer Research
Cancer Res (2020) 80 (4): 890–900.
https://doi.org/10.1158/0008-5472.CAN-19-2830
Published: 14 February 2020
View article titled, NAMPT Inhibition Suppresses Cancer Stem-like Cells Associated with Therapy-Induced Senescence in Ovarian Cancer
Open the PDF for NAMPT Inhibition Suppresses Cancer Stem-like Cells Associated with Therapy-Induced Senescence in Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer

Takeshi Fukumoto, Nail Fatkhutdinov, Joseph A. Zundell, Evgenii N. Tcyganov, Timothy Nacarelli, Sergey Karakashev, Shuai Wu, Qin Liu, Dmitry I. Gabrilovich, Rugang Zhang
Journal: Cancer Research
Cancer Res (2019) 79 (21): 5482–5489.
https://doi.org/10.1158/0008-5472.CAN-19-1302
Published: 01 November 2019
View article titled, HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer
Open the PDF for HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

N6-Methylation of Adenosine of FZD10 mRNA Contributes to PARP Inhibitor Resistance

Takeshi Fukumoto, Hengrui Zhu, Timothy Nacarelli, Sergey Karakashev, Nail Fatkhutdinov, Shuai Wu, Pingyu Liu, Andrew V. Kossenkov, Louise C. Showe, Stephanie Jean, Lin Zhang, Rugang Zhang
Journal: Cancer Research
Cancer Res (2019) 79 (11): 2812–2820.
https://doi.org/10.1158/0008-5472.CAN-18-3592
Published: 03 June 2019
View article titled, N<sup>6</sup>-Methylation of Adenosine of <em>FZD10</em> mRNA Contributes to PARP Inhibitor Resistance
Open the PDF for N<sup>6</sup>-Methylation of Adenosine of <em>FZD10</em> mRNA Contributes to PARP Inhibitor Resistance in another window
Includes: Supplementary data