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Timothy J. Yeatman
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Journal Articles

Abstract 6430: Gene expression signature quantifies the cellular contribution of the tumor vs. the microenvironment in determining colorectal cancer prognosis and therapeutic outcome

Mingli Yang, Timothy J. Yeatman, Michael V. Nebozhyn, Michael J. Schell, Lance Pflieger, Andrey Loboda, Warren J. Pledger, Ramani Soundararajan, Michelle Maurin, Heiman Wang, Jetsen Rodriguez Silva, Ashley Alden
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6430.
https://doi.org/10.1158/1538-7445.AM2024-6430
Published: 22 March 2024
View article titled, Abstract 6430: Gene expression signature quantifies the cellular contribution of the tumor <em>vs.</em> the microenvironment in determining colorectal cancer prognosis and therapeutic outcome
Journal Articles

Abstract 4343: Development of an APC and TP53-based duplex sequencing assay to positively predict colorectal cancer response to EGFR inhibitors

Mingli Yang, Michael J. Schell, Lance Pflieger, Jesse Salk, Timothy J. Yeatman
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4343.
https://doi.org/10.1158/1538-7445.AM2023-4343
Published: 04 April 2023
View article titled, Abstract 4343: Development of an <em>APC</em> and <em>TP53</em>-based duplex sequencing assay to positively predict colorectal cancer response to EGFR inhibitors
Journal Articles

Abstract 5366: Hotspot mutations of TP53 sensitize APC-mutated colorectal cancer cells to cetuximab in vitro

Mingli Yang, Heiman Wang, Thomas B. Davis, Lance Pflieger, Ramya Thota, W. Jack Pledger, Timothy J. Yeatman
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5366.
https://doi.org/10.1158/1538-7445.AM2022-5366
Published: 15 June 2022
View article titled, Abstract 5366: Hotspot mutations of TP53 sensitize APC-mutated colorectal cancer cells to cetuximab <em>in vitro</em>
Journal Articles

Abstract 1083: A novel role of SRC in mediating bypass resistance to MEK inhibition in colorectal cancer stem cells

Mingli Yang, Thomas B. Davis B. Davis, Michael V. Nebozhyn, Andrey Loboda, Heiman Wang, Michael J. Schell, Lance Pflieger, Ramya Thota, W. Jack Pledger, Timothy J. Yeatman
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1083.
https://doi.org/10.1158/1538-7445.AM2021-1083
Published: 01 July 2021
View article titled, Abstract 1083: A novel role of SRC in mediating bypass resistance to MEK inhibition in colorectal cancer stem cells
Journal Articles

Abstract 3170: BRAF expression is associated with poor survival in colorectal cancers independent of BRAF (V600E) mutation

Mingli Yang, Michael J. Schell, Timothy J. Yeatman
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3170.
https://doi.org/10.1158/1538-7445.AM2019-3170
Published: 01 July 2019
View article titled, Abstract 3170: <em>BRAF</em> expression is associated with poor survival in colorectal cancers independent of <em>BRAF</em> (V600E) mutation
Journal Articles

Abstract 2571: An integral genomic/expression analysis reveals a cooperative role of APC and TP53 mutations in identifying cetuximab-sensitive colorectal cancer

Mingli Yang, Michael J. Schell, Andrey Loboda, Michael V. Nebozhyn, Jiannong Li, Jamie K. Teer, W. Jack Pledger, Timothy J. Yeatman
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2571.
https://doi.org/10.1158/1538-7445.AM2018-2571
Published: 01 July 2018
View article titled, Abstract 2571: An integral genomic/expression analysis reveals a cooperative role of <em>APC</em> and <em>TP53</em> mutations in identifying cetuximab-sensitive colorectal cancer
Journal Articles

Abstract LB-343: Development of plasma cell-free DNA (cfDNA) assays for early cancer detection: first insights from the Circulating Cell-Free Genome Atlas Study (CCGA)

Alexander A. Aravanis, Geoffrey R. Oxnard, Tara Maddala, Earl Hubbell, Oliver Venn, Arash Jamshidi, Ling Shen, Hamed Amini, John A. Beausang, Craig Betts, Daniel Civello, Konstantin Davydov, Saniya Fazullina, Darya Filippova, Sante Gnerre, Samuel Gross, Chenlu Hou, Roger Jiang, Byoungsok Jung, Kathryn Kurtzman, Collin Melton, Shivani Nautiyal, Jonathan Newman, Joshua Newman, Cosmos Nicolaou, Richard Rava, Onur Sakarya, Ravi Vijaya Satya, Seyedmehdi Shojaee, Kristan Steffen, Anton Valouev, Hui Xu, Jeanne Yue, Nan Zhang, Jose Baselga, Rosanna Lapham, Daron G. Davis, David Smith, Donald Richards, Michael V. Seiden, Charles Swanton, Timothy J. Yeatman, Robert Tibshirani, Christina Curtis, Sylvia K. Plevritis, Richard Williams, Eric Klein, Anne-Renee Hartman, Minetta C. Liu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-343.
https://doi.org/10.1158/1538-7445.AM2018-LB-343
Published: 01 July 2018
View article titled, Abstract LB-343: Development of plasma cell-free DNA (cfDNA) assays for early cancer detection: first insights from the Circulating Cell-Free Genome Atlas Study (CCGA)
Journal Articles

Abstract 4135: Inactivation/loss of PTPRS promotes ERK activation that sensitizes colorectal cancer cells to ERK inhibitors

Thomas B. Davis, Mingli Yang, Michael J. Schell, Heiman Wang, Le Ma, W. Jack Pledger, Timothy J. Yeatman
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4135.
https://doi.org/10.1158/1538-7445.AM2017-4135
Published: 01 July 2017
View article titled, Abstract 4135: Inactivation/loss of PTPRS promotes ERK activation that sensitizes colorectal cancer cells to ERK inhibitors
Journal Articles

Abstract 5013: A 3D culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer

Bhuminder Singh, Cunxi Li, Ramona Graves-Deal, Haiting Ma, Alina Starchenko, William H. Fry, Yuanyuan Lu, Yang Wang, Galina Bogatcheva, Mohseen P. Khan, Ginger L. Milne, Shilin Zhao, Gregory D. Ayers, Nenggan Li, Mary K. Washington, Timothy J. Yeatman, Oliver G. McDonald, Qi Liu, Robert J. Coffey
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5013.
https://doi.org/10.1158/1538-7445.AM2017-5013
Published: 01 July 2017
View article titled, Abstract 5013: A 3D culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer
Journal Articles

Abstract 3175: Identification of a unique subpopulation of mesenchymal-like colorectal cancers associated with better survival

Mingli Yang, Michael J. Schell, Michael V. Nebozhyn, Andrey Loboda, Timothy J. Yeatman
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3175.
https://doi.org/10.1158/1538-7445.AM2016-3175
Published: 15 July 2016
View article titled, Abstract 3175: Identification of a unique subpopulation of mesenchymal-like colorectal cancers associated with better survival
Journal Articles

Abstract 2981: The epithelial to mesenchymal transition (EMT) produces colorectal cancer subpopulations with strikingly different mutation profiles

Mingli Yang, Michael J. Schell, Norman H. Lee, Timothy J. Yeatman
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2981.
https://doi.org/10.1158/1538-7445.AM2015-2981
Published: 01 August 2015
View article titled, Abstract 2981: The epithelial to mesenchymal transition (EMT) produces colorectal cancer subpopulations with strikingly different mutation profiles
Journal Articles

Abstract LB-188: Co-evolution of primary and metastatic colorectal cancer

Timothy J. Yeatman, Jamie Teer, Danielle Grenawalt, Richard Kim, Michael J. Schell
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-188.
https://doi.org/10.1158/1538-7445.AM2014-LB-188
Published: 01 October 2014
View article titled, Abstract LB-188: Co-evolution of primary and metastatic colorectal cancer
Journal Articles

Abstract LB-43: MiR-147 is a novel tumor suppressor that reverses EMT and native resistance to EGFR inhibitors by inactivating Akt and activating Stat3.

Chang Gong Lee, Michael Gruidl, Cindy R. Timmee, Susan McCarthy, Timothy J. Yeatman
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-43.
https://doi.org/10.1158/1538-7445.AM2013-LB-43
Published: 15 April 2013
View article titled, Abstract LB-43: MiR-147 is a novel tumor suppressor that reverses EMT and native resistance to EGFR inhibitors by inactivating Akt and activating Stat3.
Journal Articles

Abstract 1156: Cell-surface marker discovery for colorectal cancer

Kamini Sewda, Jonathan W. Wojtkowiak, Steven Enkemann, Alexis S. Lopez, Domenico Coppola, David Shibata, Timothy J. Yeatman, Robert J. Gillies, David L. Morse
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1156.
https://doi.org/10.1158/1538-7445.AM2012-1156
Published: 15 April 2012
View article titled, Abstract 1156: Cell-surface marker discovery for colorectal cancer
Journal Articles

Abstract 435: Targeted exome sequencing to understand tumor progression and identify targeted therapies

Danielle Greenawalt, James Hardwick, Theresa Zhang, Mark Ferguson, Patrick Lewis, Shane Hunstman, Shawn O'Brien, Zhidong Tu, Sergey Lezhnin, Andrey Loboda, Cathy Kerzner, Timothy J. Yeatman, William Dalton, Hongyue Dai
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 435.
https://doi.org/10.1158/1538-7445.AM2012-435
Published: 15 April 2012
View article titled, Abstract 435: Targeted exome sequencing to understand tumor progression and identify targeted therapies
Journal Articles

Abstract 1679: Increased expression of hCAS/CSE1L in colorectal cancer: Correlation with tumor progression

Evita Henderson-Jackson, Steven A. Eschrich, Dung-Tsa Chen, Timothy J. Yeatman, Domenico Coppola, Mokenge P. Malafa
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1679.
https://doi.org/10.1158/1538-7445.AM2011-1679
Published: 15 April 2011
View article titled, Abstract 1679: Increased expression of hCAS/CSE1L in colorectal cancer: Correlation with tumor progression
Journal Articles

Abstract 2961: Expression of ZEB1, an E-cadherin repressor correlates with poor patient survival in colon cancer and mediates claudin-1 dependent repression of E-cadherin

Amar B. Singh, Josh J. Smith, Moorthy Krishnan, X Chen, Steven Eschrich, Timothy J. Yeatman, Robert D. Beauchamp, Punita Dhawan
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2961.
https://doi.org/10.1158/1538-7445.AM10-2961
Published: 15 April 2010
View article titled, Abstract 2961: Expression of ZEB1, an E-cadherin repressor correlates with poor patient survival in colon cancer and mediates claudin-1 dependent repression of E-cadherin
Journal Articles

Abstract 3076: BVES, a novel adhesion molecule, acts as tumor modifier through modulation of tight-junction-associated signaling

Christopher S. Williams, Jin-Long Yang, Sai H. Presley, Baolin Zhang, Daniel O. Rosenblatt, Mary Kay Washington, Jesse J. Smith, Xi Chen, Steven Eschrich, Timothy J. Yeatman, Robert D. Beauchamp, Min S. Chang
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3076.
https://doi.org/10.1158/1538-7445.AM10-3076
Published: 15 April 2010
View article titled, Abstract 3076: BVES, a novel adhesion molecule, acts as tumor modifier through modulation of tight-junction-associated signaling
Journal Articles

Abstract 4636: Increased expression of CSE1L/hCAS in colorectal cancer: Correlation with tumor progression

Steven C. Shivers, Domenico Coppola, Steven A. Eschrich, Dung-Tsa Chen, David Shibata, Timothy J. Yeatman, Mokenge P. Malafa
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4636.
https://doi.org/10.1158/1538-7445.AM10-4636
Published: 15 April 2010
View article titled, Abstract 4636: Increased expression of CSE1L/hCAS in colorectal cancer: Correlation with tumor progression
Journal Articles

On the Eve of Personalized Medicine in Oncology

Timothy J. Yeatman, James Mule, William S. Dalton, Dan Sullivan
Journal: Cancer Research
Cancer Res (2008) 68 (18): 7250–7252.
https://doi.org/10.1158/0008-5472.CAN-08-1374
Published: 14 September 2008
View article titled, On the Eve of Personalized Medicine in Oncology
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