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Tian-Li Wang
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Journal Articles

Abstract C036: Pharmacological modulation of glutamine metabolism alters macrophage activity and tumor immune responses

Jiawei Fan, Sumeng Qi, Ie-Ming Shih, Tian-Li Wang
Journal: Cancer Research
Cancer Res (2024) 84 (22_Supplement): C036.
https://doi.org/10.1158/1538-7445.TUMBODY-C036
Published: 17 November 2024
View article titled, Abstract C036: Pharmacological modulation of glutamine metabolism alters macrophage activity and tumor immune responses
Journal Articles

Dual Inhibition of SYK and EGFR Overcomes Chemoresistance by Inhibiting CDC6 and Blocking DNA Replication

Jayaprakash Mandal, Tiffany Nicole Jones, Juliane Marie Liberto, Stephanie Gaillard, Tian-Li Wang, Ie-Ming Shih
Journal: Cancer Research
Cancer Res (2024) 84 (22): 3881–3893.
https://doi.org/10.1158/0008-5472.CAN-24-0769
Published: 15 November 2024
View article titled, Dual Inhibition of SYK and EGFR Overcomes Chemoresistance by Inhibiting CDC6 and Blocking DNA Replication
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Includes: Supplementary data
Journal Articles

Abstract 7003: Microfluidic platform for DNA methylation profiling towards early detection of ovarian cancer

Chrissy O'Hersey, Yang Zhao, Thomas R. Pisanic, Tian-Li Wang, Ie-Ming Shih, Tza-Huei Jeff Wang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7003.
https://doi.org/10.1158/1538-7445.AM2024-7003
Published: 22 March 2024
View article titled, Abstract 7003: Microfluidic platform for DNA methylation profiling towards early detection of ovarian cancer
Journal Articles

Temozolomide Sensitizes ARID1A-Mutated Cancers to PARP Inhibitors

Zheng-Cheng Yu, Tianhe Li, Ellen Tully, Peng Huang, Chih-Ning Chen, Philipp Oberdoerffer, Stephanie Gaillard, Ie-Ming Shih, Tian-Li Wang
Journal: Cancer Research
Cancer Res (2023) 83 (16): 2750–2762.
https://doi.org/10.1158/0008-5472.CAN-22-3646
Published: 15 August 2023
View article titled, Temozolomide Sensitizes <em>ARID1A</em>-Mutated Cancers to PARP Inhibitors
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Includes: Supplementary data
Journal Articles

Abstract 2231: Epigenomic profiling uncovers distinct enrichment patterns of PBX1 super-enhancer among lung adenocarcinoma

Douglas M. Mansell, Maya Fridrich, Feng Jiang, Benjamin Chen, Ayushi Patel, Tian Li-Wang, Charles A. Powell, Hideo Watanabe
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2231.
https://doi.org/10.1158/1538-7445.AM2023-2231
Published: 04 April 2023
View article titled, Abstract 2231: Epigenomic profiling uncovers distinct enrichment patterns of <em>PBX1</em> super-enhancer among lung adenocarcinoma
Journal Articles

Spatial Transcriptomic Analysis of Ovarian Cancer Precursors Reveals Reactivation of IGFBP2 during Pathogenesis

Yeh Wang, Peng Huang, Brant G. Wang, Tricia Murdock, Leslie Cope, Fang-Chi Hsu, Tian-Li Wang, Ie-Ming Shih
Journal: Cancer Research
Cancer Res (2022) 82 (24): 4528–4541.
https://doi.org/10.1158/0008-5472.CAN-22-1620
Published: 16 December 2022
View article titled, Spatial Transcriptomic Analysis of Ovarian Cancer Precursors Reveals Reactivation of IGFBP2 during Pathogenesis
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Includes: Supplementary data
Journal Articles

Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers

Yao-An Shen, Jiaxin Hong, Ryoichi Asaka, Shiho Asaka, Fang-Chi Hsu, Yohan Suryo Rahmanto, Jin-Gyoung Jung, Yu-Wei Chen, Ting-Tai Yen, Alicja Tomaszewski, Cissy Zhang, Nabeel Attarwala, Angelo M. DeMarzo, Ben Davidson, Chi-Mu Chuang, Xi Chen, Stephanie Gaillard, Anne Le, Ie-Ming Shih, Tian-Li Wang
Journal: Cancer Research
Cancer Res (2020) 80 (20): 4514–4526.
https://doi.org/10.1158/0008-5472.CAN-19-3971
Published: 15 October 2020
View article titled, Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers
Open the PDF for Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract 1966: A novel small-molecule compound targeting PBX1-DNA interaction impedes cancer cell survival and carboplatin resistance

Yao-An Shen, Jin Jung, Yohan Suryo Rahmanto, Licia Selleri, Ie-Ming Shih, Chi-Mu Chuang, Tian-Li Wang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1966.
https://doi.org/10.1158/1538-7445.AM2018-1966
Published: 01 July 2018
View article titled, Abstract 1966: A novel small-molecule compound targeting PBX1-DNA interaction impedes cancer cell survival and carboplatin resistance
Journal Articles

Abstract 2493: Inactivation of ARID1A-SWI/SNF complex alters chromatin compactness at enhancer regions and affects transcription of key tumor signaling circuitry

Yohan Suryo Rahmanto, Xu Shi, Wenjing Shen, Tsutomu Miyamoto, Yu Yu, Xi Chen, Meng-Horng Lee, Vivek Singh, Michele I. Vitolo, Denis Wirtz, Ronny Drapkin, Jianhua Xuan, Ie-Ming Shih, Tian-Li Wang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2493.
https://doi.org/10.1158/1538-7445.AM2018-2493
Published: 01 July 2018
View article titled, Abstract 2493: Inactivation of ARID1A-SWI/SNF complex alters chromatin compactness at enhancer regions and affects transcription of key tumor signaling circuitry
Journal Articles

Abstract 3991: Profiling the immune tumor microenvironment in primary and recurrent epithelial ovarian cancer

Laureen S. Ojalvo, Elizabeth D. Thompson, Tian-Li Wang, Alan K. Meeker, Ie-Ming Shih, Amanda N. Fader, Ashley Cimino-Mathews, Leisha A. Emens
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3991.
https://doi.org/10.1158/1538-7445.AM2017-3991
Published: 01 July 2017
View article titled, Abstract 3991: Profiling the immune tumor microenvironment in primary and recurrent epithelial ovarian cancer
Journal Articles

Ovarian Cancer Chemoresistance Relies on the Stem Cell Reprogramming Factor PBX1

Jin-Gyoung Jung, Ie-Ming Shih, Joon Tae Park, Emily Gerry, Tae Hoen Kim, Ayse Ayhan, Karen Handschuh, Ben Davidson, Amanda N. Fader, Licia Selleri, Tian-Li Wang
Journal: Cancer Research
Cancer Res (2016) 76 (21): 6351–6361.
https://doi.org/10.1158/0008-5472.CAN-16-0980
Published: 31 October 2016
View article titled, Ovarian Cancer Chemoresistance Relies on the Stem Cell Reprogramming Factor PBX1
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Includes: Supplementary data
Journal Articles

Abstract B18: Identification and characterization of NAC1 as a profilin1/actin-binding protein that is essential for effective cytokinesis in cancer cells

Kai Lee Yap, Stephanie I. Fraley, Michelle M. Thiaville, Natini Jinawath, Kentaro Nakayama, Jian-Long Wang, Denis Wirtz, Tian-Li Wang, le-Ming Shih
Journal: Cancer Research
Cancer Res (2011) 71 (18_Supplement): B18.
https://doi.org/10.1158/1538-7445.FBCR11-B18
Published: 28 October 2014
View article titled, Abstract B18: Identification and characterization of NAC1 as a profilin1/actin-binding protein that is essential for effective cytokinesis in cancer cells
Journal Articles

Abstract A45: The tumor suppressor role of ARID1A in gynecologic cancer

Bin Guan, Tian-Li Wang, le-Ming Shih
Journal: Cancer Research
Cancer Res (2011) 71 (18_Supplement): A45.
https://doi.org/10.1158/1538-7445.FBCR11-A45
Published: 28 October 2014
View article titled, Abstract A45: The tumor suppressor role of ARID1A in gynecologic cancer
Journal Articles

Abstract A63: Rsf-1, a chromatin remodeling protein, interacts with shelterin protein hRap1 and induces telomere shortening

Ren-Chin Wu, Bin Guan, Yusuke Kobayashi, Tian-Li Wang, Ie-Ming Shih
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): A63.
https://doi.org/10.1158/1538-7445.CEC13-A63
Published: 13 May 2014
View article titled, Abstract A63: Rsf-1, a chromatin remodeling protein, interacts with shelterin protein hRap1 and induces telomere shortening
Journal Articles

Abstract 401: Gene expression signatures differentiate primary and metastatic uterine leiomyosarcoma.

Ben Davidson, Vera Maria Abeler, Mette Førsund, Arild Holth, Ie-Ming Shih, Gunnar B. Kristensen, Li Chen, Yanqin Yang, Tian-Li Wang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 401.
https://doi.org/10.1158/1538-7445.AM2013-401
Published: 15 April 2013
View article titled, Abstract 401: Gene expression signatures differentiate primary and metastatic uterine leiomyosarcoma.
Journal Articles

Abstract LB-259: Arid1a loss in collaboration with PI3K pathway activation leads to ovarian tumorigenesis in mouse.

Bin Guan, Tian-Li Wang, Ie-Ming Shih
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-259.
https://doi.org/10.1158/1538-7445.AM2013-LB-259
Published: 15 April 2013
View article titled, Abstract LB-259: Arid1a loss in collaboration with PI3K pathway activation leads to ovarian tumorigenesis in mouse.
Journal Articles

NAC1 Is an Actin-Binding Protein That Is Essential for Effective Cytokinesis in Cancer Cells

Kai Lee Yap, Stephanie I. Fraley, Michelle M. Thiaville, Natini Jinawath, Kentaro Nakayama, Jianlong Wang, Tian-Li Wang, Denis Wirtz, Ie-Ming Shih
Journal: Cancer Research
Cancer Res (2012) 72 (16): 4085–4096.
https://doi.org/10.1158/0008-5472.CAN-12-0302
Published: 14 August 2012
View article titled, NAC1 Is an Actin-Binding Protein That Is Essential for Effective Cytokinesis in Cancer Cells
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Includes: Multimedia, Supplementary data
Journal Articles

Defining NOTCH3 Target Genes in Ovarian Cancer

Xu Chen, Michelle M. Thiaville, Li Chen, Alexander Stoeck, Jianhua Xuan, Min Gao, Ie-Ming Shih, Tian-Li Wang
Journal: Cancer Research
Cancer Res (2012) 72 (9): 2294–2303.
https://doi.org/10.1158/0008-5472.CAN-11-2181
Published: 30 April 2012
View article titled, Defining NOTCH3 Target Genes in Ovarian Cancer
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Includes: Supplementary data
Journal Articles

Abstract 5536: TP53 and MED12 mutations in uterine smooth muscle tumors

Elisabetta Kuhn, Anna Yemelyanova, Tian-Li Wang, Robert Kurman, Ie-Ming Shih
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5536.
https://doi.org/10.1158/1538-7445.AM2012-5536
Published: 15 April 2012
View article titled, Abstract 5536: <em>TP53</em> and <em>MED12</em> mutations in uterine smooth muscle tumors
Journal Articles

Abstract 815: The role of spleen tyrosine kinase (SYK) in paclitaxel resistant ovarian cancer

Stephanie Gaillard, Alexander Stoeck, Ben Davidson, Tian-Li Wang, Ie-Ming Shih
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 815.
https://doi.org/10.1158/1538-7445.AM2012-815
Published: 15 April 2012
View article titled, Abstract 815: The role of spleen tyrosine kinase (SYK) in paclitaxel resistant ovarian cancer