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Thorsten Stiewe
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Journal Articles

Abstract 2487: KRAS and TP53 co-mutation predicts benefit of immune checkpoint blockade in lung adenocarcinoma

Jan Budczies, Eva Romanovsky, Martina Kirchner, Olaf Neumann, Miriam Blasi, Johannes Schnorbach, Rajiv Shah, Farastuk Bozorgmehr, Rajkumar Savai, Thorsten Stiewe, Solange Peters, Peter Schirmacher, Thomas Michael, Daniel Kazdal, Petros Christopoulos, Albrecht Stenzinger
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2487.
https://doi.org/10.1158/1538-7445.AM2024-2487
Published: 22 March 2024
View article titled, Abstract 2487: KRAS and TP53 co-mutation predicts benefit of immune checkpoint blockade in lung adenocarcinoma
Journal Articles

Abstract 5508: Single-cell spatial landscape of the mutation-specific human lung tumor immune microenvironment

Rajender Nandigama, Bassem Ben Cheikh, Ning Ma, Jochen Wilhelm, Laura Klotz, Florian Eichhorn, Mark Kriegsmann, Marek Bartkuhn, Jamal Nabhanizadeh, Sascha Seidel, Thorsten Stiewe, Albrecht Stenzinger, Andreas Weigert, Mario Looso, Friedrich Grimminger, Werner Seeger, Soni Savai Pullamsetti, Niyati Jhaveri, Hauke Winter, Rajkumar Savai
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5508.
https://doi.org/10.1158/1538-7445.AM2024-5508
Published: 22 March 2024
View article titled, Abstract 5508: Single-cell spatial landscape of the mutation-specific human lung tumor immune microenvironment
Journal Articles

The HDAC2-SP1 Axis Orchestrates Protumor Macrophage Polarization

Xiang Zheng, Poonam Sarode, Andreas Weigert, Kati Turkowski, Prakash Chelladurai, Stefan Günther, Carsten Kuenne, Hauke Winter, Albrecht Stenzinger, Simone Reu, Friedrich Grimminger, Thorsten Stiewe, Werner Seeger, Soni Savai Pullamsetti, Rajkumar Savai
Journal: Cancer Research
Cancer Res (2023) 83 (14): 2345–2357.
https://doi.org/10.1158/0008-5472.CAN-22-1270
Published: 14 July 2023
View article titled, The HDAC2-SP1 Axis Orchestrates Protumor Macrophage Polarization
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Includes: Supplementary data
Journal Articles

Abstract 2607: Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by comprehensive mRNA expression analysis

Jan Budczies, Eva Romanovsky, Klaus Kluck, Iordanis Ourailidis, Michael Menzel, Susanne Beck, Markus Ball, Daniel Kazdal, Petros Christopoulos, Peter Schirmacher, Thorsten Stiewe, Albrecht Stenzinger
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2607.
https://doi.org/10.1158/1538-7445.AM2023-2607
Published: 04 April 2023
View article titled, Abstract 2607: Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by comprehensive mRNA expression analysis
Journal Articles

Abstract PD4-02: PD4-02 Spatial and temporal heterogeneity of predictive and prognostic signatures in triple-negative breast cancer treated with neoadjuvant combination immune-chemotherapy

Carsten Denkert, Andreas Schneeweiss, Julia Rey, Akira Hattesohl, Thomas Karn, Michael Braun, Paul Jank, Jens Huober, Hans-Peter Sinn, Dirk-Michael Zahm, Claus Hanusch, Frederik Marmé, Jenny Furlanetto, Jörg Thomalla, Jens-Uwe Blohmer, Marion van Mackelenbergh, Thorsten Stiewe, Peter Staib, Christian Jackisch, Julia Teply-Szymanski, Peter A. Fasching, Bruno V. Sinn, Michael Untch, Karsten Weber, Sibylle Loibl
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): PD4-02.
https://doi.org/10.1158/1538-7445.SABCS22-PD4-02
Published: 01 March 2023
View article titled, Abstract PD4-02: PD4-02 Spatial and temporal heterogeneity of predictive and prognostic signatures in triple-negative breast cancer treated with neoadjuvant combination immune-chemotherapy
Journal Articles

Abstract PD2-04: Molecular plasticity of luminal breast cancer and response to CDK 4/6 inhibition - The biomarker program of the PENELOPE-B trial investigating post-neoadjuvant palbociclib

Carsten Denkert, Frederik Marmé, Miguel Martin, Michael Untch, Hervé Bonnefoi, Sung-Bae Kim, Harry Bear, Agnieszka Witkiewicz, Seock-Ah Im, Angela DeMichele, Laura Van’t Veer, Nicole McCarthy, Thorsten Stiewe, Karen A. Gelmon, José A. García-Sáenz, Catherine M. Kelly, Toralf Reimer, Erik Knudsen, Nicholas Turner, Federico Rojo, Peter A. Fasching, Julia Teply-Szymanski, Yuan Liu, Masakazu Toi, Hope S. Rugo, Michael Gnant, Andreas Makris, Bärbel Felder, Karsten Weber, Sibylle Loibl
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): PD2-04.
https://doi.org/10.1158/1538-7445.SABCS21-PD2-04
Published: 15 February 2022
View article titled, Abstract PD2-04: Molecular plasticity of luminal breast cancer and response to CDK 4/6 inhibition - The biomarker program of the PENELOPE-B trial investigating post-neoadjuvant palbociclib
Journal Articles

Correction: Metastasis-Associated Protein 2 Represses NF-κB to Reduce Lung Tumor Growth and Inflammation

Nefertiti El-Nikhely, Annika Karger, Poonam Sarode, Indrabahadur Singh, Andreas Weigert, Astrid Wietelmann, Thorsten Stiewe, Reinhard Dammann, Ludger Fink, Friedrich Grimminger, Guillermo Barreto, Werner Seeger, Soni S. Pullamsetti, Ulf R. Rapp, Rajkuma Savai
Journal: Cancer Research
Cancer Res (2022) 82 (4): 736.
https://doi.org/10.1158/0008-5472.CAN-21-4331
Published: 15 February 2022
View article titled, Correction: Metastasis-Associated Protein 2 Represses NF-κB to Reduce Lung Tumor Growth and Inflammation
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Journal Articles

Phosphorylation Control of p53 DNA-Binding Cooperativity Balances Tumorigenesis and Aging

Oleg Timofeev, Lukas Koch, Constantin Niederau, Alina Tscherne, Jean Schneikert, Maria Klimovich, Sabrina Elmshäuser, Marie Zeitlinger, Marco Mernberger, Andrea Nist, Christian Osterburg, Volker Dötsch, Martin Hrabé de Angelis, Thorsten Stiewe
Journal: Cancer Research
Cancer Res (2020) 80 (23): 5231–5244.
https://doi.org/10.1158/0008-5472.CAN-20-2002
Published: 02 December 2020
View article titled, Phosphorylation Control of p53 DNA-Binding Cooperativity Balances Tumorigenesis and Aging
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Includes: Supplementary data
Journal Articles

Metastasis-Associated Protein 2 Represses NF-κB to Reduce Lung Tumor Growth and Inflammation

Nefertiti El-Nikhely, Annika Karger, Poonam Sarode, Indrabahadur Singh, Andreas Weigert, Astrid Wietelmann, Thorsten Stiewe, Reinhard Dammann, Ludger Fink, Friedrich Grimminger, Guillermo Barreto, Werner Seeger, Soni S. Pullamsetti, Ulf R. Rapp, Rajkumar Savai
Journal: Cancer Research
Cancer Res (2020) 80 (19): 4199–4211.
https://doi.org/10.1158/0008-5472.CAN-20-1158
Published: 02 October 2020
View article titled, Metastasis-Associated Protein 2 Represses NF-κB to Reduce Lung Tumor Growth and Inflammation
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Includes: Supplementary data
Journal Articles

Transactivation-deficient ΔTA-p73 Acts as an Oncogene

Thorsten Stiewe, Sonja Zimmermann, Andreja Frilling, Helmut Esche, Brigitte M. Pützer
Journal: Cancer Research
Cancer Res (2002) 62 (13): 3598–3602.
Published: 01 July 2002
View article titled, Transactivation-deficient ΔTA-p73 Acts as an Oncogene
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Journal Articles

Therapeutic Efficacy of E2F1 in Pancreatic Cancer Correlates with TP73 Induction

Florian Rödicker, Thorsten Stiewe, Sonja Zimmermann, Brigitte M. Pützer
Journal: Cancer Research
Cancer Res (2001) 61 (19): 7052–7055.
Published: 01 October 2001
View article titled, Therapeutic Efficacy of E2F1 in Pancreatic Cancer Correlates with <em>TP73</em> Induction
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Journal Articles

E1A Overcomes the Apoptosis Block in BCR-ABL+ Leukemia Cells and Renders Cells Susceptible to Induction of Apoptosis by Chemotherapeutic Agents

Thorsten Stiewe, Keiarasch Parssanedjad, Helmut Esche, Bertram Opalka, Brigitte M. Pützer
Journal: Cancer Research
Cancer Res (2000) 60 (14): 3957–3964.
Published: 15 July 2000
View article titled, E1A Overcomes the Apoptosis Block in BCR-ABL+ Leukemia Cells and Renders Cells Susceptible to Induction of Apoptosis by Chemotherapeutic Agents
Open the PDF for E1A Overcomes the Apoptosis Block in BCR-ABL+ Leukemia Cells and Renders Cells Susceptible to Induction of Apoptosis by Chemotherapeutic Agents in another window