Page 1 | Search Results | Cancer Research | American Association for Cancer Research

1-13 of 13

Sort by

Sort Order Select

Journal Articles

Abstract 2529: Optimization of small molecules targeting BMI1 protein expression. Part 1. Amino-thiazoles: the first-in-class highly potent inhibitors of BMI1 protein

Nadiya Sydorenko, Ramil Baiazitov, Soongyu Choi, Chang-Sun Lee, Liangxian Cao, Thomas W. Davis, Neil G. Almstead, Young-Choon Moon

Cancer Res (2014) 74 (19_Supplement): 2529.

https://doi.org/10.1158/1538-7445.AM2014-2529

Published: 01 October 2014

View articletitled, Abstract 2529: Optimization of small molecules targeting BMI1 protein expression. Part 1. Amino-thiazoles: the first-in-class highly potent inhibitors of BMI1 protein

Journal Articles

Abstract 5517: PTC596-induced Bmi1 hyper-phosphorylation via Cdk1/2 activation resulting in tumor stem cell depletion

Min Jung Kim, Liangxian Cao, Josephine Sheedy, Nicole Risher, Melissa Dumble, Chang-Sun Lee, Nadiya Sydorenko, Ramil Baiazitov, Wu Du, Young-Choon Moon, Marla L. Weetall, Joseph Colacino, Thomas W. Davis

Cancer Res (2014) 74 (19_Supplement): 5517.

https://doi.org/10.1158/1538-7445.AM2014-5517

Published: 01 October 2014

View articletitled, Abstract 5517: PTC596-induced Bmi1 hyper-phosphorylation via Cdk1/2 activation resulting in tumor stem cell depletion

Journal Articles

Abstract 2528: Optimization of small molecules targeting BMI1 protein expression. Part 2. Improved potency, oral bioavailability, and in vivo efficacy of amino-pyrazines and amino-pyridines

Ramil Baiazitov, Nadiya Sydorenko, Hongyu Ren, Wu Du, Steve Paget, Richard Wilde, Ronggang Liu, Chang-Sun Lee, Liangxian Cao, Thomas W. Davis, Neil G. Almstead, Young-Choon Moon

Cancer Res (2014) 74 (19_Supplement): 2528.

https://doi.org/10.1158/1538-7445.AM2014-2528

Published: 01 October 2014

View articletitled, Abstract 2528: Optimization of small molecules targeting BMI1 protein expression. Part 2. Improved potency, oral bioavailability, and in vivo efficacy of amino-pyrazines and amino-pyridines

Journal Articles

Post-transcriptional inhibition of vascular endothelial growth factor (VEGF) expression arrests tumor growth at a prevascular stage

Paivi Ullner, Jianzhong Huang, Judy Tsai, Marla Weetall, Charles Romfo, Thomas W. Davis, Nadarajan Tamilarasu, Jessica J. Kandel, Darrell J. Yamashiro

Cancer Res (2005) 65 (9_Supplement): 909.

Published: 01 May 2005

View articletitled, Post-transcriptional inhibition of vascular endothelial growth factor (VEGF) expression arrests tumor growth at a prevascular stage

Journal Articles

Post-transcriptional control as a novel approach to anti-angiogenesis: development of a small molecule that reduces the production of tumor vascular endothelial growth factor A (VEGF)

Cancer Res (2005) 65 (9_Supplement): 912.

Published: 01 May 2005

View articletitled, Post-transcriptional control as a novel approach to anti-angiogenesis: development of a small molecule that reduces the production of tumor vascular endothelial growth factor A (VEGF)

Journal Articles

Post-transcriptional control as a novel approach to anti-angiogenesis: Small molecules which reduce VEGF levels

Thomas W. Davis, Liangxian Cao, Soongyu Choi, Jenelle Zelinski, Carriebeth Dellarosa, Panayiota Trifillis, Hongyan Qi, Nadarajan Tamilarasu, Duck-Hyung Lee, Samit Hirawat, Donald Corson, Seongwoo Hwang, William Lennox, Marla Weetall, Young-Choon Moon, Joseph Colacino, Neil Almstead, John Babiak, Stuart Peltz

Cancer Res (2004) 64 (7_Supplement): 592.

Published: 01 April 2004

View articletitled, Post-transcriptional control as a novel approach to anti-angiogenesis: Small molecules which reduce VEGF levels

Journal Articles

Synergy between Celecoxib and Radiotherapy Results from Inhibition of Cyclooxygenase-2-Derived Prostaglandin E₂, a Survival Factor for Tumor and Associated Vasculature

Thomas W. Davis, Janet M. O’Neal, Mark D. Pagel, Ben S. Zweifel, Pramod P. Mehta, Deborah M. Heuvelman, Jaime L. Masferrer

Cancer Res (2004) 64 (1): 279–285.

https://doi.org/10.1158/0008-5472.CAN-03-1168

Published: 16 January 2004

View articletitled, Synergy between Celecoxib and Radiotherapy Results from Inhibition of Cyclooxygenase-2-Derived Prostaglandin E2, a Survival Factor for Tumor and Associated Vasculature

Journal Articles

Direct Evidence for a Role of Cyclooxygenase 2-derived Prostaglandin E₂ in Human Head and Neck Xenograft Tumors

Ben S. Zweifel, Thomas W. Davis, Richard L. Ornberg, Jaime L. Masferrer

Cancer Res (2002) 62 (22): 6706–6711.

Published: 15 November 2002

View articletitled, Direct Evidence for a Role of Cyclooxygenase 2-derived Prostaglandin E2 in Human Head and Neck Xenograft Tumors

Journal Articles

Cyclooxygenase-2 Inhibition with Celecoxib Enhances Antitumor Efficacy and Reduces Diarrhea Side Effect of CPT-11

Ovidiu C. Trifan, William F. Durham, Valerie S. Salazar, Jennifer Horton, Benjamin D. Levine, Ben S. Zweifel, Thomas W. Davis, Jaime L. Masferrer

Cancer Res (2002) 62 (20): 5778–5784.

Published: 15 October 2002

View articletitled, Cyclooxygenase-2 Inhibition with Celecoxib Enhances Antitumor Efficacy and Reduces Diarrhea Side Effect of CPT-11

Journal Articles

Selective Radiosensitization of Drug-resistant MutS Homologue-2 (MSH2) Mismatch Repair-deficient Cells by Halogenated Thymidine (dThd) Analogues: Msh2 Mediates dThd Analogue DNA Levels and the Differential Cytotoxicity and Cell Cycle Effects of the dThd Analogues and 6-Thioguanine

Suzanne E. Berry, Thomas W. Davis, Jane E. Schupp, Hwa-Shin Hwang, Niels de Wind, Timothy J. Kinsella

Cancer Res (2000) 60 (20): 5773–5780.

Published: 15 October 2000

View articletitled, Selective Radiosensitization of Drug-resistant MutS Homologue-2 (MSH2) Mismatch Repair-deficient Cells by Halogenated Thymidine (dThd) Analogues: Msh2 Mediates dThd Analogue DNA Levels and the Differential Cytotoxicity and Cell Cycle Effects of the dThd Analogues and 6-Thioguanine

Journal Articles

Radiosensitivity of Thymidylate Synthase-deficient Human Tumor Cells Is Affected by Progression through the G₁ Restriction Point into S-Phase: Implications for Fluoropyrimidine Radiosensitization

Hwa-Shin Hwang, Thomas W. Davis, Janet A. Houghton, Timothy J. Kinsella

Cancer Res (2000) 60 (1): 92–100.

Published: 01 January 2000

View articletitled, Radiosensitivity of Thymidylate Synthase-deficient Human Tumor Cells Is Affected by Progression through the G1 Restriction Point into S-Phase: Implications for Fluoropyrimidine Radiosensitization

Journal Articles

The Mismatch Repair Protein, hMLH1, Mediates 5-Substituted Halogenated Thymidine Analogue Cytotoxicity, DNA Incorporation, and Radiosensitization in Human Colon Cancer Cells

Suzanne E. Berry, Christopher Garces, Hwa-Shin Hwang, Keith Kunugi, Mark Meyers, Thomas W. Davis, David A. Boothman, Timothy J. Kinsella

Cancer Res (1999) 59 (8): 1840–1845.

Published: 15 April 1999

View articletitled, The Mismatch Repair Protein, hMLH1, Mediates 5-Substituted Halogenated Thymidine Analogue Cytotoxicity, DNA Incorporation, and Radiosensitization in Human Colon Cancer Cells

Journal Articles

Defective Expression of the DNA Mismatch Repair Protein, MLH1, Alters G₂-M Cell Cycle Checkpoint Arrest following Ionizing Radiation

Thomas W. Davis, Carmell Wilson-Van Patten, Mark Meyers, Keith A. Kunugi, Scott Cuthill, Catherine Reznikoff, Christopher Garces, C. Richard Boland, Timothy J. Kinsella, Richard Fishel, David A. Boothman

Cancer Res (1998) 58 (4): 767–778.

Published: 01 February 1998

View articletitled, Defective Expression of the DNA Mismatch Repair Protein, MLH1, Alters G2-M Cell Cycle Checkpoint Arrest following Ionizing Radiation

Update search

NARROW

Format

Journal

Article Type

Issue Section

Date

Availability

Abstract 2529: Optimization of small molecules targeting BMI1 protein expression. Part 1. Amino-thiazoles: the first-in-class highly potent inhibitors of BMI1 protein

Abstract 5517: PTC596-induced Bmi1 hyper-phosphorylation via Cdk1/2 activation resulting in tumor stem cell depletion

Abstract 2528: Optimization of small molecules targeting BMI1 protein expression. Part 2. Improved potency, oral bioavailability, and in vivo efficacy of amino-pyrazines and amino-pyridines

Post-transcriptional inhibition of vascular endothelial growth factor (VEGF) expression arrests tumor growth at a prevascular stage

Post-transcriptional control as a novel approach to anti-angiogenesis: development of a small molecule that reduces the production of tumor vascular endothelial growth factor A (VEGF)

Post-transcriptional control as a novel approach to anti-angiogenesis: Small molecules which reduce VEGF levels

Synergy between Celecoxib and Radiotherapy Results from Inhibition of Cyclooxygenase-2-Derived Prostaglandin E₂, a Survival Factor for Tumor and Associated Vasculature

Direct Evidence for a Role of Cyclooxygenase 2-derived Prostaglandin E₂ in Human Head and Neck Xenograft Tumors

Cyclooxygenase-2 Inhibition with Celecoxib Enhances Antitumor Efficacy and Reduces Diarrhea Side Effect of CPT-11

Selective Radiosensitization of Drug-resistant MutS Homologue-2 (MSH2) Mismatch Repair-deficient Cells by Halogenated Thymidine (dThd) Analogues: Msh2 Mediates dThd Analogue DNA Levels and the Differential Cytotoxicity and Cell Cycle Effects of the dThd Analogues and 6-Thioguanine

Radiosensitivity of Thymidylate Synthase-deficient Human Tumor Cells Is Affected by Progression through the G₁ Restriction Point into S-Phase: Implications for Fluoropyrimidine Radiosensitization

The Mismatch Repair Protein, hMLH1, Mediates 5-Substituted Halogenated Thymidine Analogue Cytotoxicity, DNA Incorporation, and Radiosensitization in Human Colon Cancer Cells

Defective Expression of the DNA Mismatch Repair Protein, MLH1, Alters G₂-M Cell Cycle Checkpoint Arrest following Ionizing Radiation

Email alerts

AACR Journals

Update search

Email alerts

AACR Journals

This Feature Is Available To Subscribers Only