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Abstract 4360: Integrative analysis of multiplex interphase FISH copy number with whole exome sequencing identifies tumor evolution in Stage II colon cancer

Sanam Yaghoubi, Kerstin Heselmeyer-Haddad, Ivan Archilla, Carolina Parra, Darawalee Wangsa, Giancarlo Castellano, Jack Zhu, Diba Yaghoubi, Sara Lahoz, Veronica Pablo-Fontecha3, Daniela Hirsch, Wei-Dong Chen, Thomas Ried, Miriam Cuatrecasas, Paul S. Meltzer, Jordi Camps

Cancer Res (2024) 84 (6_Supplement): 4360.

https://doi.org/10.1158/1538-7445.AM2024-4360

Published: 22 March 2024

View articletitled, Abstract 4360: Integrative analysis of multiplex interphase FISH copy number with whole exome sequencing identifies tumor evolution in Stage II colon cancer

Journal Articles

Abstract 314: Intratumor genetic heterogeneity dictates metastatic subclones in stage II colon cancer

Sanam Yaghoubi, Kerstin Heselmeyer-Haddad, Ivan Archilla, Carolina Parra, Darawalee Wangsa, Giancarlo Castellano, Sara Lahoz, Veronica Pablo-Fontecha, Daniela Hirsch, Wei-Dong Chen, Thomas Ried, Miriam Cuatrecasas, Paul S. Meltzer, Jordi Camps

Cancer Res (2023) 83 (7_Supplement): 314.

https://doi.org/10.1158/1538-7445.AM2023-314

Published: 04 April 2023

View articletitled, Abstract 314: Intratumor genetic heterogeneity dictates metastatic subclones in stage II colon cancer

Journal Articles

Abstract 2153: ATR inhibition augments the efficacy of the lurbinectedin in small cell lung cancer

Christopher William Schultz, Yang Zhang, Haiqing Fu, Yasuhisa Murai, Darawalee Wangsa, Devon Atkinson, Liton Saha, Brian Elenbaas, Chien-Fei Lee, Astrid Zimmerman, Thomas Ried, Frank Zenke, Zoe Weaver, Rajaa Elmeskini, Yves Pommier, Anish Thomas

Cancer Res (2022) 82 (12_Supplement): 2153.

https://doi.org/10.1158/1538-7445.AM2022-2153

Published: 15 June 2022

View articletitled, Abstract 2153: ATR inhibition augments the efficacy of the lurbinectedin in small cell lung cancer

Journal Articles

Abstract PO-106: Genomic heterogeneity and clonal dynamics of resistance evolution and metastatic progression in rectal cancer

Daniela Hirsch, Judith Lieberich, Kerstin Heselmeyer-Haddad, Yonca Ceribas, Michael Kelly, Keyur Talsania, Yongmei Zhao, Timo Gaiser, Thomas Ried

Cancer Res (2020) 80 (21_Supplement): PO-106.

https://doi.org/10.1158/1538-7445.TUMHET2020-PO-106

Published: 03 November 2020

View articletitled, Abstract PO-106: Genomic heterogeneity and clonal dynamics of resistance evolution and metastatic progression in rectal cancer

Journal Articles

Abstract 2498: miFISH single cell analysis as a potential tool to stratify the progression risk in patients with Atypical Ductal Hyperplasia (ADH)

Kiara Whitaker, Jausheng Tzeng, Daniela Hirsch, Irianna Torres, Steven Brower, Gert Auer, Miguel Sanchez, Thomas Ried, Kerstin Heselmeyer-Haddad

Cancer Res (2020) 80 (16_Supplement): 2498.

https://doi.org/10.1158/1538-7445.AM2020-2498

Published: 15 August 2020

View articletitled, Abstract 2498: miFISH single cell analysis as a potential tool to stratify the progression risk in patients with Atypical Ductal Hyperplasia (ADH)

Journal Articles

Abstract 2189: Genomic dynamics in breast cancer progression analyzed by miFISH analysis

Irianna Marie Torres, Leanora Hernandez, Jausheng Tzeng, Russell Schwartz, Alejandro Schaffer, Edward Michael Gertz, Daniela Hirsch, Steven Brower, Miguel Sanchez, Gert Auer, Kerstin Heselmeyer-Haddad, Thomas Ried

Cancer Res (2018) 78 (13_Supplement): 2189.

https://doi.org/10.1158/1538-7445.AM2018-2189

Published: 01 July 2018

View articletitled, Abstract 2189: Genomic dynamics in breast cancer progression analyzed by miFISH analysis

Journal Articles

SMYD5 Controls Heterochromatin and Chromosome Integrity during Embryonic Stem Cell Differentiation

Benjamin L. Kidder, Runsheng He, Darawalee Wangsa, Hesed M. Padilla-Nash, M. Margarida Bernardo, Shijie Sheng, Thomas Ried, Keji Zhao

Cancer Res (2017) 77 (23): 6729–6745.

https://doi.org/10.1158/0008-5472.CAN-17-0828

Published: 30 November 2017

View articletitled, SMYD5 Controls Heterochromatin and Chromosome Integrity during Embryonic Stem Cell Differentiation

Includes: Supplementary data

Journal Articles

ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer

Cancer Res (2017) 77 (22): 6267–6281.

https://doi.org/10.1158/0008-5472.CAN-17-0570

Published: 14 November 2017

View articletitled, ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer

Includes: Supplementary data

Journal Articles

Abstract 4789: A novel MIF signaling pathway drives the malignant character of pancreatic cancer by targeting NR3C2

Cancer Res (2017) 77 (13_Supplement): 4789.

https://doi.org/10.1158/1538-7445.AM2017-4789

Published: 01 July 2017

View articletitled, Abstract 4789: A novel MIF signaling pathway drives the malignant character of pancreatic cancer by targeting NR3C2

Journal Articles

Abstract 3947: Intratumor heterogeneity impacts treatment response in rectal carcinoma

Rüdiger Meyer, Nicole E. McNeil, Darawalee Wangsa, Lena Anthuber, Noam Auslander, Danny Wangsa, Zhongqiu Zhang, Daniel Rosenberg, Eytan Ruppin, Jens K. Habermann, Thomas Ried

Cancer Res (2017) 77 (13_Supplement): 3947.

https://doi.org/10.1158/1538-7445.AM2017-3947

Published: 01 July 2017

View articletitled, Abstract 3947: Intratumor heterogeneity impacts treatment response in rectal carcinoma

Journal Articles

Abstract 1438: The dynamics of genetic aberrations in Crohn's disease associated colorectal carcinogenesis

Daniela D. Hirsch, Darawalee Wangsa, Yue Hu, Jack Zhu, David Petersen, Daniel C. Edelman, Paul S. Meltzer, Bao Tran, Kerstin Heselmeyer-Haddad, Thomas Ried, Timo Gaiser

Cancer Res (2017) 77 (13_Supplement): 1438.

https://doi.org/10.1158/1538-7445.AM2017-1438

Published: 01 July 2017

View articletitled, Abstract 1438: The dynamics of genetic aberrations in Crohn's disease associated colorectal carcinogenesis

Journal Articles

Abstract 4387: The clonal composition of colorectal cancer cell lines is defined by the maintenance of specific genomic imbalances, not by ongoing chromosomal instability

Darawalee Wangsa, Madison Schiefer, Daniel Bronder, Hesed Padilla-Nash, Irianna Torres, Lidia Warner, Yue Hu, E Michael Gertz, Russell Schwartz, Alejandro A. Schäffer, Daniela Hirsch, Timo Gaiser, Rüdiger Meyer, Jordi Camps, Kerstin Heselmeyer-Haddad, Thomas Ried

Cancer Res (2017) 77 (13_Supplement): 4387.

https://doi.org/10.1158/1538-7445.AM2017-4387

Published: 01 July 2017

View articletitled, Abstract 4387: The clonal composition of colorectal cancer cell lines is defined by the maintenance of specific genomic imbalances, not by ongoing chromosomal instability

Journal Articles

Abstract 4760: Wnt/β-catenin signaling mediates resistance of colorectal cancer cell lines to chemoradiotherapy

Georg Emons, Melanie Spitzner, Sebastian Reineke, Noam Auslander, Frank Kramer, Margret Rave-Fraenk, Jochen Gaedcke, Michael Ghadimi, Thomas Ried, Marian Grade

Cancer Res (2017) 77 (13_Supplement): 4760.

https://doi.org/10.1158/1538-7445.AM2017-4760

Published: 01 July 2017

View articletitled, Abstract 4760: Wnt/β-catenin signaling mediates resistance of colorectal cancer cell lines to chemoradiotherapy

Journal Articles

Abstract B34: A Novel MIF-driven Signaling Drives Disease Aggressiveness by Targeting NR3C2 in Pancreatic Cancer

Shouhui Yang, Peijun He, Jian Wang, Aaron Schetter, Wei Tang, Naotake Funamizu, Katsuhiko Yanaga, Tadashi Uwagawa, Abhay R. Satoskar, Jochen Gaedcke, Markus Bernhardt, B. Michael Ghadimi, Matthias M. Gaida, Frank Bergmann, Jens Werner, Thomas Ried, Nader Hanna, H. Richard Alexander, S. Perwez Hussain

Cancer Res (2016) 76 (24_Supplement): B34.

https://doi.org/10.1158/1538-7445.PANCA16-B34

Published: 14 December 2016

View articletitled, Abstract B34: A Novel MIF-driven Signaling Drives Disease Aggressiveness by Targeting NR3C2 in Pancreatic Cancer

Journal Articles

Abstract 1979: Comprehensive analysis of the dynamics of aberrant WNT signaling on global gene expression and higher order nuclear structure in human cells

Markus Brown, Darawalee Wangsa, Yue Hu, Thomas Ried

Cancer Res (2016) 76 (14_Supplement): 1979.

https://doi.org/10.1158/1538-7445.AM2016-1979

Published: 15 July 2016

View articletitled, Abstract 1979: Comprehensive analysis of the dynamics of aberrant WNT signaling on global gene expression and higher order nuclear structure in human cells

Journal Articles

Abstract 2402: The impact of genomic heterogeneity in colorectal carcinoma on therapy response - a study on monoclonal primary colon cultures

Rüdiger Meyer, Nicole E. McNeil, Ewa Krawczyk, Daniel W. Rosenberg, Zhongqiu Zhang, Richard Schlegel, Jens K. Habermann, Thomas Ried

Cancer Res (2016) 76 (14_Supplement): 2402.

https://doi.org/10.1158/1538-7445.AM2016-2402

Published: 15 July 2016

View articletitled, Abstract 2402: The impact of genomic heterogeneity in colorectal carcinoma on therapy response - a study on monoclonal primary colon cultures

Journal Articles

Abstract 1653: A novel role for Wnt/β-catenin signaling in mediating resistance of colorectal cancer to chemoradiotherapy

Georg Emons, Melanie Spitzner, Sebastian Reineke, Frank Kramer, Margret Rave-Fraenk, Jochen Gaedcke, Michael Ghadimi, Thomas Ried, Marian Grade

Cancer Res (2016) 76 (14_Supplement): 1653.

https://doi.org/10.1158/1538-7445.AM2016-1653

Published: 15 July 2016

View articletitled, Abstract 1653: A novel role for Wnt/β-catenin signaling in mediating resistance of colorectal cancer to chemoradiotherapy

Journal Articles

A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2

Cancer Res (2016) 76 (13): 3838–3850.

https://doi.org/10.1158/0008-5472.CAN-15-2841

Published: 30 June 2016

View articletitled, A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2

Includes: Supplementary data

Journal Articles

Abstract 2182: Reconstructing evolutionary models of tumor progression from single-cell heterogeneity data

Salim A. Chowdhury, E. Michael Gertz, Darawalee Wangsa, Kerstin Heselmeyer-Haddad, Thomas Ried, Alejandro Schaeffer, Russell Schwartz

Cancer Res (2015) 75 (15_Supplement): 2182.

https://doi.org/10.1158/1538-7445.AM2015-2182

Published: 01 August 2015

View articletitled, Abstract 2182: Reconstructing evolutionary models of tumor progression from single-cell heterogeneity data

Journal Articles

Abstract 3031: Replication stress and DNA damage promote genomic instability in near-tetraploid colorectal cancer cells

Isabel Quintanilla, Darawalee Wangsa, Markus Brown, Amaia Ercilla, Greg Klus, Maria Vila, Juan José Lozano, Zoltan Szallsi, Neus Agell, Antoni Castells, Thomas Ried, Jordi Camps

Cancer Res (2015) 75 (15_Supplement): 3031.

https://doi.org/10.1158/1538-7445.AM2015-3031

Published: 01 August 2015

View articletitled, Abstract 3031: Replication stress and DNA damage promote genomic instability in near-tetraploid colorectal cancer cells

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Abstract 4360: Integrative analysis of multiplex interphase FISH copy number with whole exome sequencing identifies tumor evolution in Stage II colon cancer

Abstract 314: Intratumor genetic heterogeneity dictates metastatic subclones in stage II colon cancer

Abstract 2153: ATR inhibition augments the efficacy of the lurbinectedin in small cell lung cancer

Abstract PO-106: Genomic heterogeneity and clonal dynamics of resistance evolution and metastatic progression in rectal cancer

Abstract 2498: miFISH single cell analysis as a potential tool to stratify the progression risk in patients with Atypical Ductal Hyperplasia (ADH)

Abstract 2189: Genomic dynamics in breast cancer progression analyzed by miFISH analysis

SMYD5 Controls Heterochromatin and Chromosome Integrity during Embryonic Stem Cell Differentiation

ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer

Abstract 4789: A novel MIF signaling pathway drives the malignant character of pancreatic cancer by targeting NR3C2

Abstract 3947: Intratumor heterogeneity impacts treatment response in rectal carcinoma

Abstract 1438: The dynamics of genetic aberrations in Crohn's disease associated colorectal carcinogenesis

Abstract 4387: The clonal composition of colorectal cancer cell lines is defined by the maintenance of specific genomic imbalances, not by ongoing chromosomal instability

Abstract 4760: Wnt/β-catenin signaling mediates resistance of colorectal cancer cell lines to chemoradiotherapy

Abstract B34: A Novel MIF-driven Signaling Drives Disease Aggressiveness by Targeting NR3C2 in Pancreatic Cancer

Abstract 1979: Comprehensive analysis of the dynamics of aberrant WNT signaling on global gene expression and higher order nuclear structure in human cells

Abstract 2402: The impact of genomic heterogeneity in colorectal carcinoma on therapy response - a study on monoclonal primary colon cultures

Abstract 1653: A novel role for Wnt/β-catenin signaling in mediating resistance of colorectal cancer to chemoradiotherapy

A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2

Abstract 2182: Reconstructing evolutionary models of tumor progression from single-cell heterogeneity data

Abstract 3031: Replication stress and DNA damage promote genomic instability in near-tetraploid colorectal cancer cells

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