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Thomas N. Darling
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Journal Articles

Human Pluripotent Stem Cell–Derived TSC2-Haploinsufficient Smooth Muscle Cells Recapitulate Features of Lymphangioleiomyomatosis

Lisa M. Julian, Sean P. Delaney, Ying Wang, Alexander A. Goldberg, Carole Doré, Julien Yockell-Lelièvre, Roger Y. Tam, Krinio Giannikou, Fiona McMurray, Molly S. Shoichet, Mary-Ellen Harper, Elizabeth P. Henske, David J. Kwiatkowski, Thomas N. Darling, Joel Moss, Arnold S. Kristof, William L. Stanford
Journal: Cancer Research
Cancer Res (2017) 77 (20): 5491–5502.
https://doi.org/10.1158/0008-5472.CAN-17-0925
Published: 15 October 2017
View article titled, Human Pluripotent Stem Cell–Derived <em>TSC2</em>-Haploinsufficient Smooth Muscle Cells Recapitulate Features of Lymphangioleiomyomatosis
Open the PDF for Human Pluripotent Stem Cell–Derived <em>TSC2</em>-Haploinsufficient Smooth Muscle Cells Recapitulate Features of Lymphangioleiomyomatosis in another window
Includes: Supplementary data
Journal Articles

Abstract 5510: Tranilast inhibits growth of skin tumor cells in a xenograft mouse model of tuberous sclerosis complex.

Shaowei Li, Ji-an Wang, Rajesh L. Thangapazham, Peter Klover, Joel Moss, Thomas N. Darling
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5510.
https://doi.org/10.1158/1538-7445.AM2013-5510
Published: 15 April 2013
View article titled, Abstract 5510: Tranilast inhibits growth of skin tumor cells in a xenograft mouse model of tuberous sclerosis complex.
Journal Articles

Abstract 2469: Increased cathepsin B expression in cultured tuberous sclerosis skin tumor cells and patient tumor tissues

Shaowei Li, Ying Liu, Ji-an Wang, Joel Moss, Thomas N. Darling
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2469.
https://doi.org/10.1158/1538-7445.AM2012-2469
Published: 15 April 2012
View article titled, Abstract 2469: Increased cathepsin B expression in cultured tuberous sclerosis skin tumor cells and patient tumor tissues
Journal Articles

Abstract 2501: Rapamycin inhibits epidermal cell proliferation in a xenograft model of tuberous sclerosis skin tumors

Shaowei Li, Rajesh Thangapazham, Ji-an Wang, Sangeetha Rajesh, Joel Moss, Thomas N. Darling
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2501.
https://doi.org/10.1158/1538-7445.AM10-2501
Published: 15 April 2010
View article titled, Abstract 2501: Rapamycin inhibits epidermal cell proliferation in a xenograft model of tuberous sclerosis skin tumors
Journal Articles

TSC2 Loss in Lymphangioleiomyomatosis Cells Correlated with Expression of CD44v6, a Molecular Determinant of Metastasis

Gustavo Pacheco-Rodriguez, Wendy K. Steagall, Denise M. Crooks, Linda A. Stevens, Hiroshi Hashimoto, Shaowei Li, Ji-an Wang, Thomas N. Darling, Joel Moss
Journal: Cancer Research
Cancer Res (2007) 67 (21): 10573–10581.
https://doi.org/10.1158/0008-5472.CAN-07-1356
Published: 01 November 2007
View article titled, <em>TSC2</em> Loss in Lymphangioleiomyomatosis Cells Correlated with Expression of CD44v6, a Molecular Determinant of Metastasis
Open the PDF for <em>TSC2</em> Loss in Lymphangioleiomyomatosis Cells Correlated with Expression of CD44v6, a Molecular Determinant of Metastasis in another window
Includes: Supplementary data
Journal Articles

Epiregulin, a member of the EGF family, is upregulated in tuberous sclerosis skin tumor cells.

Shaowei Li, Fumiko Takeuchi, Ji-An Wang, Qingyuan Fan, Gustavo Pacheco-Rodriguez, Joel Moss, Thomas N. Darling
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1178.
Published: 15 April 2006
View article titled, Epiregulin, a member of the EGF family, is upregulated in tuberous sclerosis skin tumor cells.
Journal Articles

MCP-1 is a paracrine factor overexpressed by tuberous sclerosis skin tumor cells and tuberin-deficient fibroblasts.

Shaowei Li, Fumiko Takeuchi, Ji-An Wang, Christopher Fuller, Gustavo Pacheco-Rodriguez, Joel Moss, Thomas N. Darling
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 43.
Published: 01 May 2005
View article titled, MCP-1 is a paracrine factor overexpressed by tuberous sclerosis skin tumor cells and tuberin-deficient fibroblasts.
Journal Articles

Perivascular Cells Harboring Multiple Endocrine Neoplasia Type 1 Alterations Are Neoplastic Cells in Angiofibromas

Alexander O. Vortmeyer, Roland Böni, Svetlana D. Pack, Thomas N. Darling, Zhengping Zhuang
Journal: Cancer Research
Cancer Res (1999) 59 (2): 274–278.
Published: 15 January 1999
View article titled, Perivascular Cells Harboring <em>Multiple Endocrine Neoplasia Type 1</em> Alterations Are Neoplastic Cells in Angiofibromas
Open the PDF for Perivascular Cells Harboring <em>Multiple Endocrine Neoplasia Type 1</em> Alterations Are Neoplastic Cells in Angiofibromas in another window