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Journal Articles

Abstract 1598: Deep targeted sequencing of colorectal cancer cases to study associations of molecular subtypes with clinical, genetic, and lifestyle risk factors

Syed H. Zaidi, Amanda I. Phipps, Tabitha A. Harrison, Robert S. Steinfelder, Quang Trinh, Barbara L. Banbury, Adilya Rafikova, Megan Van Tassel, Emma Reid, Stefanie Brezina, Marios Giannakis, Charles S. Fuchs, Li Hsu, Andrea Gsur, Shuji Ogino, Steven Gallinger, Polly A. Newcomb, Peter T. Campbell, Wei Sun, Thomas J. Hudson, Ulrike Peters
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1598.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1598
Published: 01 July 2019
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Abstract NG05: TP53-mediated human cancer susceptibility is defined by epigenetic dysregulation of microRNA-34A

Nardin Samuel, Gavin Wilson, Genevieve Deblois, Badr Id Said, Nicholas W. Fischer, Mathieu Lemire, Youliang Lou, Weili Li, Roumiana Alexandrova, Ana Novokmet, James Tran, Kim E. Nichols, Jonathan L. Finlay, Sanaa Choufani, Marc Remke, Vijay Ramaswamy, Florence M.G. Cavalli, Christine Elser, Lynn Meister, Michael D. Taylor, Uri Tabori, Meredith Irwin, Rosanna Weksberg, Jonathan D. Wasserman, Jean Gariepy, Mathieu Lupien, Daniele Merico, Andrew Paterson, Jordan R. Hansford, Maria Isabel W. Achatz, Thomas J. Hudson, David Malkin
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): NG05.
DOI: https://doi.org/10.1158/1538-7445.AM2017-NG05
Published: 01 July 2017
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Journal Articles

Abstract 1300: Genetic predictors of gene expression associated with risk of colorectal cancer

Stephanie A. Bien, Xingyi Guo, Yu-Ru Su, Tabitha A. Harrison, Conghui Qu, Yingchang Lu, Jiron Long, Sai Chen, Andrew T. Chan, David V. Conti, Hyun M. Kang, Michael Hoffmeister, Thomas J. Hudson, Mark A. Jenkins, Loic Le Marchand, Polly A. Newcomb, Martha L. Slattery, Emily White, Goncalo R. Abeçasis, Stephen B. Gruber, Deborah A. Nickerson, Stephanie L. Schmit, Graham Casey, Li Hsu, Wei Zheng, Ulrike Peters, GECCO-CCFR-AAAC-CORECT
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1300.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1300
Published: 01 July 2017
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Journal Articles

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

Gordon Fehringer, Peter Kraft, Paul D. Pharoah, Rosalind A. Eeles, Nilanjan Chatterjee, Fredrick R. Schumacher, Joellen M. Schildkraut, Sara Lindström, Paul Brennan, Heike Bickeböller, Richard S. Houlston, Maria Teresa Landi, Neil Caporaso, Angela Risch, Ali Amin Al Olama, Sonja I. Berndt, Edward L. Giovannucci, Henrik Grönberg, Zsofia Kote-Jarai, Jing Ma, Kenneth Muir, Meir J. Stampfer, Victoria L. Stevens, Fredrik Wiklund, Walter C. Willett, Ellen L. Goode, Jennifer B. Permuth, Harvey A. Risch, Brett M. Reid, Stephane Bezieau, Hermann Brenner, Andrew T. Chan, Jenny Chang-Claude, Thomas J. Hudson, Jonathan K. Kocarnik, Polly A. Newcomb, Robert E. Schoen, Martha L. Slattery, Emily White, Muriel A. Adank, Habibul Ahsan, Kristiina Aittomäki, Laura Baglietto, Carl Blomquist, Federico Canzian, Kamila Czene, Isabel dos-Santos-Silva, A. Heather Eliassen, Jonine D. Figueroa, Dieter Flesch-Janys, Olivia Fletcher, Montserrat Garcia-Closas, Mia M. Gaudet, Nichola Johnson, Per Hall, Aditi Hazra, Rebecca Hein, Albert Hofman, John L. Hopper, Astrid Irwanto, Mattias Johansson, Rudolf Kaaks, Muhammad G. Kibriya, Peter Lichtner, Jianjun Liu, Eiliv Lund, Enes Makalic, Alfons Meindl, Bertram Müller-Myhsok, Taru A. Muranen, Heli Nevanlinna, Petra H. Peeters, Julian Peto, Ross L. Prentice, Nazneen Rahman, Maria Jose Sanchez, Daniel F. Schmidt, Rita K. Schmutzler, Melissa C. Southey, Rulla Tamimi, Ruth C. Travis, Clare Turnbull, Andre G. Uitterlinden, Zhaoming Wang, Alice S. Whittemore, Xiaohong R. Yang, Wei Zheng, Daniel D. Buchanan, Graham Casey, David V. Conti, Christopher K. Edlund, Steven Gallinger, Robert W. Haile, Mark Jenkins, Loïc Le Marchand, Li Li, Noralene M. Lindor, Stephanie L. Schmit, Stephen N. Thibodeau, Michael O. Woods, Thorunn Rafnar, Julius Gudmundsson, Simon N. Stacey, Kari Stefansson, Patrick Sulem, Y. Ann Chen, Jonathan P. Tyrer, David C. Christiani, Yongyue Wei, Hongbing Shen, Zhibin Hu, Xiao-Ou Shu, Kouya Shiraishi, Atsushi Takahashi, Yohan Bossé, Ma'en Obeidat, David Nickle, Wim Timens, Matthew L. Freedman, Qiyuan Li, Daniela Seminara, Stephen J. Chanock, Jian Gong, Ulrike Peters, Stephen B. Gruber, Christopher I. Amos, Thomas A. Sellers, Douglas F. Easton, David J. Hunter, Christopher A. Haiman, Brian E. Henderson, Rayjean J. Hung
Journal: Cancer Research
Cancer Res (2016) 76 (17): 5103–5114.
DOI: https://doi.org/10.1158/0008-5472.CAN-15-2980
Published: 31 August 2016
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Includes: Supplementary data
Journal Articles

Abstract 130: International Cancer Genome Consortium (ICGC)

Jennifer L. Jennings, Thomas J. Hudson
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 130.
DOI: https://doi.org/10.1158/1538-7445.AM2016-130
Published: 15 July 2016
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Journal Articles

Abstract 5287: Heterogeneity of mutation calling and annotation: a survey of cancer next-generation sequencing initiatives by the Global Alliance for Genomics and Health (GA4GH)

Daniel J. Vis, Jeremy Lewin, Lillian Siu, Rachel Liao, Jean Claude Zenklusen, Fabien Calvo, Edit Szepessy, Ana Vivancos, Valtteri Wirta, Subha Madhavan, Keunchil Park, Daniel Tan, Janessa Laskin, Melissa Brammer, Emmanuel Dias-Neto, Anthony Tolcher, Thomas J. Hudson, Charles Sawyers, Mark Lawler, Emile E. Voest
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5287.
DOI: https://doi.org/10.1158/1538-7445.AM2016-5287
Published: 15 July 2016
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Journal Articles

Abstract 5230: Large scale whole genome sequencing with imputation into GWAS improves our understanding of the genetic architecture of colorectal cancer

Jeroen Huyghe, Sai Chen, Hyun M. Kang, Tabitha A. Harrison, Sonja I. Berndt, Stephane Bézieau, Hermann Brenner, Graham Casey, Andrew T. Chan, Jenny Chang-Claude, Gallinger J. Steven, Stephen B. Gruber, Andrea Gsur, Michael Hoffmeister, Thomas J. Hudson, Loic Le Marchand, Polly A. Newcomb, John D. Potter, Conghui Qu, Martha L. Slattery, Joshua D. Smith, Emily White, Li Hsu, Goncalo R. Abecasis, Deborah A. Nickerson, Ulrike Peters
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5230.
DOI: https://doi.org/10.1158/1538-7445.AM2016-5230
Published: 15 July 2016
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Journal Articles

Abstract 1058: Novel insights into the genetic and epigenetic regulation of the MLH1 CpG island and shore in colorectal cancer

Andrea J. Savio, Mathieu Lemire, Miralem Mrkonjic, Steven Gallinger, Brent W. Zanke, Thomas J. Hudson, Bharati Bapat
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1058.
DOI: https://doi.org/10.1158/1538-7445.AM2015-1058
Published: 01 August 2015
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Journal Articles

Abstract 4664: Impact of TP53 mutations, single nucleotide variants and global methylation patterns on pre-menopausal breast cancer risk

Nardin Samuel, Mathieu Lemire, Ana Novokmet, Thomas J. Hudson, David Malkin
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4664.
DOI: https://doi.org/10.1158/1538-7445.AM2015-4664
Published: 01 August 2015
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Abstract 2966: The mutational landscape of localized gleason 6 and 7 prostate cancer

Michael E. Fraser, Veronica Y. Sabelnykova, Takafumi N. Yamaguchi, Alice Meng, Lawrence E. Heisler, Junyan Zhang, Julie Livingstone, Vincent Huang, Andre P. Masella, Fouad Yousif, Michael Xie, Nicholas J. Harding, Xihui Lin, Haiying Kong, Stephenie D. Prokopec, Alejandro Berlin, Dominique Trudel, Xuemei Luo, Timothy E. Beck, Richard de Borja, Alister D'Costa, Robert E. Denroche, Natalie S. Fox, Emilie Lalonde, Ada Wong, Taryne Chong, Michelle Sam, Jeremy Johns, Lee Timms, Nicholas Buchner, Michele Orain, Valerie Picard, Helene Hovington, Kenneth C. Chu, Christine P'ng, Bryan Lo, Francis Nguyen, Kathleen E. Houlahan, Christopher Cooper, Shaylan K. Govind, Clement Fung, Louis Lacombe, Colin C. Collins, Yves Fradet, Bernard Tetu, Theodorus van der Kwast, John McPherson, Thomas J. Hudson, Rob G. Bristow, Paul Boutros
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2966.
DOI: https://doi.org/10.1158/1538-7445.AM2015-2966
Published: 01 August 2015
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Journal Articles

Abstract 2988: International cancer genome consortium (ICGC)

Jennifer L. Jennings, Thomas J. Hudson
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2988.
DOI: https://doi.org/10.1158/1538-7445.AM2015-2988
Published: 01 August 2015
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Journal Articles

Abstract 16: Impact of germline TP53 mutations and polymorphisms in women with premenopausal breast cancer

Nardin Samuel, Ana Novokmet, Thomas J. Hudson, David Malkin
Journal: Cancer Research
Cancer Res (2014) 74 (23_Supplement): 16.
DOI: https://doi.org/10.1158/1538-7445.CANSUSC14-16
Published: 12 December 2014
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Journal Articles

Abstract 2190: Fine-mapping of common genetic variants associated with colorectal tumor risk identified potential functional variants

Mengmeng Du, Shuo Jiao, Stephanie A. Rosse, Manish Gala, Goncalo Abecasis, Stephane Bezieau, Hermann Brenner, Graham Casey, Jenny Chang-Claude, Steven Gallinger, Thomas J. Hudson, Sébastien Küry, Loic L. Marchand, Suzanne M. Leal, Polly A. Newcomb, Deborah A. Nickerson, John D. Potter, Martha L. Slattery, Li Hsu, Andrew T. Chan, Emily White, Sonja I. Berndt, Ulrike Peters
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2190.
DOI: https://doi.org/10.1158/1538-7445.AM2014-2190
Published: 01 October 2014
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Journal Articles

Abstract 4278: International Cancer Genome Consortium (ICGC)

Thomas J. Hudson, Jennifer L. Jennings
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4278.
DOI: https://doi.org/10.1158/1538-7445.AM2014-4278
Published: 01 October 2014
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Journal Articles

Abstract 5185: Redefining the somatic landscape of pancreatic adenocarcinoma

Andrew M.K. Brown, Faiyaz Notta, Mathieu Lemire, Ilinca Lungu, Robert E. Denroche, Christina Yung, Kristen Geras, Lincoln Stein, John M. Bartlett, Thomas J. Hudson, Michael H.A. Roehrl, Steven Gallinger, John D. McPherson
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5185.
DOI: https://doi.org/10.1158/1538-7445.AM2014-5185
Published: 01 October 2014
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Journal Articles

Abstract B18: Genomic analysis of pancreatic ductal adenocarcinoma.

Christina K. Yung, Christine Ouellete, Lee Timms, Michelle Sam, Kimberly Begley, Thomas J. Hudson, John D. McPherson, Lincoln D. Stein, Timothy Beck, Lakshmi Muthuswamy, Richard De Borja, Carson Holt, Rob Denroche, Fouad Yousif, Zheng Zha, Niloofar Arshadi
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): B18.
DOI: https://doi.org/10.1158/1538-7445.PANCA2012-B18
Published: 03 April 2014
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Journal Articles

Abstract 4831: Additive and multiplicative gene-environment interactions for colorectal cancer risk.

Mengmeng Du, Sonja I. Berndt, Hermann Brenner, Bette J. Caan, Peter T. Campbell, Graham Casey, Andrew Chan, Jenny Chang-Claude, Stephen J. Chanock, Nilanjan Chatterjee, David V. Conti, David Duggan, Jane C. Figueiredo, Steven Gallinger, Jian Gong, Robert W. Haile, Tabitha A. Harrison, Richard B. Hayes, Michael Hoffmeister, John L. Hopper, Li Hsu, Thomas J. Hudson, Carolyn M. Hutter, Eric J. Jacobs, Mark A. Jenkins, Shuo Jiao, Laurence N. Kolonel, Peter Kraft, Loic Le Marchand, Mathieu Lemire, Yi Lin, Noralane M. Lindor, Polly A. Newcomb, John D. Potter, Robert E. Schoen, Fredrick R. Schumacher, Daniela Seminara, Martha L. Slattery, Stephen N. Thibodeau, Cornelia M. Ulrich, Aung Ko Win, Emily White, Brent W. Zanke, Ulrike Peters
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4831.
DOI: https://doi.org/10.1158/1538-7445.AM2013-4831
Published: 15 April 2013
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Journal Articles

Abstract 2003: A molecular portrait of potentially curable prostate cancer.

Michael E. Fraser, Richard de Borja, Dominique Trudel, Nicholas J. Harding, Pablo H. Hennings-Yeomans, Alice Meng, Emilie R. Lalonde, Andrew Brown, Natalie S. Fox, Taryne Chong, Amin Zia, Michelle Sam, Jianxin Wang, Michelle A. Chan-Seng-Yue, Jeremy Johns, Lee Timms, Nicholas Buchner, Ada Wong, Fouad Yousif, Rob Denroche, Gaetano Zafarana, Maud HW Starmans, Hanbert Chen, Shaylan Govind, Francis Nguyen, Melania Pintilie, Neil Fleshner, Stanislav Volik, Lakshmi Muthuswamy, Colin C. Collins, Thomas J. Hudson, Lincoln D. Stein, Timothy Beck, John D. McPherson, Theodorus van der Kwast, Paul C. Boutros, Rob G. Bristow
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2003.
DOI: https://doi.org/10.1158/1538-7445.AM2013-2003
Published: 15 April 2013
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Journal Articles

Abstract 2004: International Cancer Genome Consortium (ICGC).

Thomas J. Hudson, Jennifer L. Jennings
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2004.
DOI: https://doi.org/10.1158/1538-7445.AM2013-2004
Published: 15 April 2013
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Journal Articles

Characterization of Gene–Environment Interactions for Colorectal Cancer Susceptibility Loci

Carolyn M. Hutter, Jenny Chang-Claude, Martha L. Slattery, Bethann M. Pflugeisen, Yi Lin, David Duggan, Hongmei Nan, Mathieu Lemire, Jagadish Rangrej, Jane C. Figueiredo, Shuo Jiao, Tabitha A. Harrison, Yan Liu, Lin S. Chen, Deanna L. Stelling, Greg S. Warnick, Michael Hoffmeister, Sébastien Küry, Charles S. Fuchs, Edward Giovannucci, Aditi Hazra, Peter Kraft, David J. Hunter, Steven Gallinger, Brent W. Zanke, Hermann Brenner, Bernd Frank, Jing Ma, Cornelia M. Ulrich, Emily White, Polly A. Newcomb, Charles Kooperberg, Andrea Z. LaCroix, Ross L. Prentice, Rebecca D. Jackson, Robert E. Schoen, Stephen J. Chanock, Sonja I. Berndt, Richard B. Hayes, Bette J. Caan, John D. Potter, Li Hsu, Stéphane Bézieau, Andrew T. Chan, Thomas J. Hudson, Ulrike Peters
Journal: Cancer Research
Cancer Res (2012) 72 (8): 2036–2044.
DOI: https://doi.org/10.1158/0008-5472.CAN-11-4067
Published: 16 April 2012
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Includes: Supplementary data