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Journal Articles

Abstract 922: Expanding the therapeutic potential of anti-PD-1 and anti-CTLA-4 therapy with innovative Fc engineering and rationale combinations for the treatment of solid tumors

Antoine J. Tanne, Sylvia Vincent, Benjamin Duckless, Elena Paltrinieri, Simarjot Pabla, Andrew Basinski, Sudesh Pawaria, Vidur Patel, Margaret Wilkens, Bishnu Joshi, Matthew Hancock, Daniel Levey, Thomas Horn, Cailin Joyce, David Savitsky, Cori Gorman, Jennifer Buell, Dhan Chand
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 922.
https://doi.org/10.1158/1538-7445.AM2020-922
Published: 15 August 2020
View article titled, Abstract 922: Expanding the therapeutic potential of anti-PD-1 and anti-CTLA-4 therapy with innovative Fc engineering and rationale combinations for the treatment of solid tumors
Journal Articles

Abstract 2721: Selective FcγR engagement by CTLA-4 antibodies results in increased functional activity

Jeremy D. Waight, Dhan Chand, Sylvia Dietrich, Randi Gombos, Thomas Horn, Ana M. Gonzalez, Mariana Manrique, Antoine Tanne, Christopher Dupont, Lukasz Swiech, Ben A. Croker, Jennifer S. Buell, Robert Stein, Alex Duncan, David A. Savitsky, Nicholas S. Wilson
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2721.
https://doi.org/10.1158/1538-7445.AM2018-2721
Published: 01 July 2018
View article titled, Abstract 2721: Selective FcγR engagement by CTLA-4 antibodies results in increased functional activity
Journal Articles

Abstract 3643: INCAGN1876, a unique GITR agonist antibody that facilitates GITR oligomerization

Ana M. Gonzalez, Mariana L. Manrique, Lukasz Swiech, Thomas Horn, Jeremy Waight, Yuqi Liu, Shiwen Lin, Dennis Underwood, Ekaterina Breous, Olivier Leger, Volker Seibert, Taha Merghoub, Roberta Zappasodi, Gerd Ritter, David Schaer, Kevin N. Heller, Kimberli Brill, Peggy Scherle, Gregory Hollis, Reid Huber, Marc van Dijk, Jennifer Buell, Robert Stein, Nicholas S. Wilson
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3643.
https://doi.org/10.1158/1538-7445.AM2017-3643
Published: 01 July 2017
View article titled, Abstract 3643: INCAGN1876, a unique GITR agonist antibody that facilitates GITR oligomerization
Journal Articles

Abstract 2346: Preclinical selectivity profile of the CDK4/6 inhibitor ribociclib (LEE011) compared with that of palbociclib and abemaciclib

Ralph Tiedt, Scott Delach, Steven Kovats, Thomas Horn, Michael Acker, Barbara Schacher Engstler, Giordano Caponigro, Fei Su
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2346.
https://doi.org/10.1158/1538-7445.AM2017-2346
Published: 01 July 2017
View article titled, Abstract 2346: Preclinical selectivity profile of the CDK4/6 inhibitor ribociclib (LEE011) compared with that of palbociclib and abemaciclib
Journal Articles

Abstract 4703: INCAGN1949, an anti-OX40 antibody with an optimal agonistic profile and the ability to selectively deplete intratumoral regulatory T cells

Ana M. Gonzalez, Mariana L. Manrique, Lukasz Swiech, Thomas Horn, Ekaterina Breous, Jeremy Waight, David Savitsky, Yuqi Liu, Shiwen Lin, Christopher Clarke, Taha Merghoub, Daniel Hirschhorn-Cymerman, David Schaer, Gerd Ritter, Jennifer Pulini, Kevin Heller, Peggy Scherle, Gregory Hollis, Reid Huber, Marc van Dijk, Jennifer Buell, Robert Stein, Nicholas Wilson
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4703.
https://doi.org/10.1158/1538-7445.AM2017-4703
Published: 01 July 2017
View article titled, Abstract 4703: INCAGN1949, an anti-OX40 antibody with an optimal agonistic profile and the ability to selectively deplete intratumoral regulatory T cells
Journal Articles

High-Order Drug Combinations Are Required to Effectively Kill Colorectal Cancer Cells

Thomas Horn, Stéphane Ferretti, Nicolas Ebel, Angela Tam, Samuel Ho, Fred Harbinski, Ali Farsidjani, Matthew Zubrowski, William R. Sellers, Robert Schlegel, Dale Porter, Erick Morris, Jens Wuerthner, Sébastien Jeay, Joel Greshock, Ensar Halilovic, Levi A. Garraway, Giordano Caponigro, Joseph Lehár
Journal: Cancer Research
Cancer Res (2016) 76 (23): 6950–6963.
https://doi.org/10.1158/0008-5472.CAN-15-3425
Published: 30 November 2016
View article titled, High-Order Drug Combinations Are Required to Effectively Kill Colorectal Cancer Cells
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Includes: Supplementary data
Journal Articles

Abstract 1311: High order drug combinations are required to effectively kill colorectal cancer cells

Thomas Horn, Stephane Ferretti, Nicolas Ebel, Angela Tam, Samuel Ho, Fred Harbinski, Ali Farsidjani, Matt Zubrowski, William R. Sellers, Robert Schlegel, Dale Porter, Erick Morris, Jens Wuerthner, Sebastien Jeay, Joel Greshock, Ensar Halilovic, Levi A. Garraway, Giordano Caponigro, Joseph Lehar
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1311.
https://doi.org/10.1158/1538-7445.AM2016-1311
Published: 15 July 2016
View article titled, Abstract 1311: High order drug combinations are required to effectively kill colorectal cancer cells
Journal Articles

Evidence for Two Tumor Suppressor Loci Associated with Proximal Chromosome 9p to q and Distal Chromosome 9q in Bladder Cancer and the Initial Screening for GAS1 and PTC Mutations

Anne R. Simoneau, Charles H. Spruck, III, Mirella Gonzalez-Zulueta, Mark L. Gonzalgo, Matilda F. Chan, Yvonne C. Tsai, Michael Dean, Kenneth Steven, Thomas Horn, Peter A. Jones
Journal: Cancer Research
Cancer Res (1996) 56 (21): 5039–5043.
Published: 01 November 1996
View article titled, Evidence for Two Tumor Suppressor Loci Associated with Proximal Chromosome 9p to q and Distal Chromosome 9q in Bladder Cancer and the Initial Screening for <em>GAS1</em> and <em>PTC</em> Mutations
Open the PDF for Evidence for Two Tumor Suppressor Loci Associated with Proximal Chromosome 9p to q and Distal Chromosome 9q in Bladder Cancer and the Initial Screening for <em>GAS1</em> and <em>PTC</em> Mutations in another window
Journal Articles

Two Molecular Pathways to Transitional Cell Carcinoma of the Bladder

Charles H. Spruck, III, Petra F. Ohneseit, Mirella Gonzalez-Zulueta, David Esrig, Noriomi Miyao, Yvonne C. Tsai, Seth P. Lerner, Christoph Schmütte, Allen S. Yang, Richard Cote, Louis Dubeau, Peter W. Nichols, Gregers G. Hermann, Kenneth Steven, Thomas Horn, Donald G. Skinner, Peter A. Jones
Journal: Cancer Research
Cancer Res (1994) 54 (3): 784–788.
Published: 01 February 1994
View article titled, Two Molecular Pathways to Transitional Cell Carcinoma of the Bladder
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Journal Articles

Microsatellite Instability in Bladder Cancer

Mirella Gonzalez-Zulueta, J. Michael Ruppert, Kaori Tokino, Yvonne C. Tsai, Charles H. Spruck, III, Noriomi Miyao, Peter W. Nichols, Gregers G. Hermann, Thomas Horn, Kenneth Steven, Ian C. Summerhayes, David Sidransky, Peter A. Jones
Journal: Cancer Research
Cancer Res (1993) 53 (23): 5620–5623.
Published: 01 December 1993
View article titled, Microsatellite Instability in Bladder Cancer
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Journal Articles

Distinct Pattern of p53 Mutations in Bladder Cancer: Relationship to Tobacco Usage

Charles H. Spruck, III, William M. Rideout, III, Aria F. Olumi, Petra F. Ohneseit, Allen S. Yang, Yvonne C. Tsai, Peter W. Nichols, Thomas Horn, Gregers G. Hermann, Kenneth Steven, Ronald K. Ross, Mimi C. Yu, Peter A. Jones
Journal: Cancer Research
Cancer Res (1993) 53 (5): 1162–1166.
Published: 01 March 1993
View article titled, Distinct Pattern of p53 Mutations in Bladder Cancer: Relationship to Tobacco Usage
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