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Thomas E. Yankeelov
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Journal Articles

Abstract 6223: Personalized MRI-informed forecasting of prostate cancer progression during active surveillance

Guillermo Lorenzo Gomez, Chengyue Wu, Joshua P. Yung, John F. Ward, Hector Gomez, Alessandro Reali, Thomas E. Yankeelov, Aradhana M. Venkatesan, Thomas J. Hughes
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6223.
https://doi.org/10.1158/1538-7445.AM2024-6223
Published: 22 March 2024
View article titled, Abstract 6223: Personalized MRI-informed forecasting of prostate cancer progression during active surveillance
Journal Articles

Abstract 850: Patient-specific, organ-scale forecasting of prostate cancer growth in active surveillance

Guillermo Lorenzo Gomez, Chengyue Wu, Joshua P. Yung, John F. Ward, Hector Gomez, Alessandro Reali, Thomas E. Yankeelov, Aradhana M. Venkatesan, Thomas J. Hughes
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 850.
https://doi.org/10.1158/1538-7445.AM2023-850
Published: 04 April 2023
View article titled, Abstract 850: Patient-specific, organ-scale forecasting of prostate cancer growth in active surveillance
Journal Articles

Abstract 845: Developing MRI-based digital-twins via mathematical modeling and deep learning to predict the response of triple-negative breast cancer to neoadjuvant therapy

Casey E. Stowers, Chengyue Wu, Sidharth Kumar, Ernesto A.B.F. Lima, Xhan Zu, Clinton Yam, Jong Bum Son, Jingfei Ma, Jonathan I. Tamir, Gaiane M. Rauch, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 845.
https://doi.org/10.1158/1538-7445.AM2023-845
Published: 04 April 2023
View article titled, Abstract 845: Developing MRI-based digital-twins via mathematical modeling and deep learning to predict the response of triple-negative breast cancer to neoadjuvant therapy
Journal Articles

Abstract 5569: Quantification of tumor-associated vasculature as an imaging biomarker for monitoring the response of triple-negative breast cancer to neoadjuvant chemotherapy

Chengyue Wu, Casey E. Stowers, Zhan Xu, Ernesto A. B. F. Lima, Clinton Yam, Jong Bum Son, Jingfei Ma, Gaiane M. Rauch, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5569.
https://doi.org/10.1158/1538-7445.AM2023-5569
Published: 04 April 2023
View article titled, Abstract 5569: Quantification of tumor-associated vasculature as an imaging biomarker for monitoring the response of triple-negative breast cancer to neoadjuvant chemotherapy
Journal Articles

MRI-Based Digital Models Forecast Patient-Specific Treatment Responses to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer

Chengyue Wu, Angela M. Jarrett, Zijian Zhou, Nabil Elshafeey, Beatriz E. Adrada, Rosalind P. Candelaria, Rania M.M. Mohamed, Medine Boge, Lei Huo, Jason B. White, Debu Tripathy, Vicente Valero, Jennifer K. Litton, Clinton Yam, Jong Bum Son, Jingfei Ma, Gaiane M. Rauch, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2022) 82 (18): 3394–3404.
https://doi.org/10.1158/0008-5472.CAN-22-1329
Published: 16 September 2022
View article titled, MRI-Based Digital Models Forecast Patient-Specific Treatment Responses to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer
Open the PDF for MRI-Based Digital Models Forecast Patient-Specific Treatment Responses to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 5064: Patient-specific forecasting of prostate cancer growth during active surveillance using an imaging-informed mechanistic model

Guillermo Lorenzo, Jon S. Heiselman, Michael A. Liss, Michael I. Miga, Hector Gomez, Thomas E. Yankeelov, Thomas J. Hughes, Alessandro Reali
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5064.
https://doi.org/10.1158/1538-7445.AM2022-5064
Published: 15 June 2022
View article titled, Abstract 5064: Patient-specific forecasting of prostate cancer growth during active surveillance using an imaging-informed mechanistic model
Journal Articles

Abstract 5050: Optimizing delivery of combination targeted and chemotherapy in a murine model of HER2+ breast cancer

Ernesto A.B.F. Lima, Reid Wyde, Anna G. Sorace, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5050.
https://doi.org/10.1158/1538-7445.AM2022-5050
Published: 15 June 2022
View article titled, Abstract 5050: Optimizing delivery of combination targeted and chemotherapy in a murine model of HER2+ breast cancer
Journal Articles

Abstract 2736: Forecasting treatment response to neoadjuvant therapy in triple-negative breast cancer via an image-guided digital twin

Chengyue Wu, Angela M. Jarrett, Zijian Zhou, Nabil Elshafeey, Beatriz E. Adrada, Rosalind P. Candelaria, Rania Mohamed, Medine Boge, Lei Huo, Jason White, Debu Tripathy, Vicente Valero, Jennifer Litton, Clinton Yam, Jong Bum Son, Jingfei Ma, Gaiane M. Rauch, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2736.
https://doi.org/10.1158/1538-7445.AM2022-2736
Published: 15 June 2022
View article titled, Abstract 2736: Forecasting treatment response to neoadjuvant therapy in triple-negative breast cancer <em>via</em> an image-guided digital twin
Journal Articles

Abstract 2742: A biology-based, mathematical model to predict the response of recurrent glioblastoma to treatment with 186Re-labeled nanoliposomes

Chase Christenson, Chengyue Wu, David A. Hormuth, Shiliang Huang, Andrew Brenner, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2742.
https://doi.org/10.1158/1538-7445.AM2022-2742
Published: 15 June 2022
View article titled, Abstract 2742: A biology-based, mathematical model to predict the response of recurrent glioblastoma to treatment with <sup>186</sup>Re-labeled nanoliposomes
Journal Articles

Abstract P1-08-08: Forecasting treatment response to neoadjuvant systemic therapy in triple negative breast cancer viamathematical modeling and quantitative MRI

Chengyue Wu, Angela M. Jarrett, Zijian Zhou, Nabil Elshafeey, Beatriz E. Adrada, Rosalind P. Candelaria, Rania M. Mohamed, Medine Boge, Lei Huo, Jason White, Debu Tripathy, Vicente Valero, Jennifer Litton, Stacy Moulder, Clinton Yam, Jong Bum Son, Jingfei Ma, Gaiane M. Rauch, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-08-08.
https://doi.org/10.1158/1538-7445.SABCS21-P1-08-08
Published: 15 February 2022
View article titled, Abstract P1-08-08: Forecasting treatment response to neoadjuvant systemic therapy in triple negative breast cancer <em>via</em>mathematical modeling and quantitative MRI
Journal Articles

Abstract P1-08-20: In silico analysis of a novel mathematical model integrating in vitro and in vivo imaging data reveals driving mechanisms of breast cancer response to NAT for personalized tumor forecasting

Guillermo Lorenzo, Angela M. Jarrett, Christian T. Meyer, Darren R. Tyson, Vito Quaranta, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-08-20.
https://doi.org/10.1158/1538-7445.SABCS21-P1-08-20
Published: 15 February 2022
View article titled, Abstract P1-08-20: <em>In silico</em> analysis of a novel mathematical model integrating <em>in vitro</em> and <em>in vivo</em> imaging data reveals driving mechanisms of breast cancer response to NAT for personalized tumor forecasting
Journal Articles

Abstract P3-03-03: Quantitative multiparametric MRI predicts response to neoadjuvant therapy in the community setting

John Virostko, Anna G Sorace, Kalina P Slavkova, Anum S Kazerouni, Angela M Jarrett, Julie C DiCarlo, Stefanie Woodard, Sarah Avery, Boone W Goodgame, Debra Patt, Thomas E Yankeelov
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-03-03.
https://doi.org/10.1158/1538-7445.SABCS21-P3-03-03
Published: 15 February 2022
View article titled, Abstract P3-03-03: Quantitative multiparametric MRI predicts response to neoadjuvant therapy in the community setting
Journal Articles

Abstract P3-02-09: Three timepoint pharmacokinetic modeling to incorporate within standard of care MRI breast exams

Julie C DiCarlo, Angela M Jarrett, Anum S Kazerouni, John Virostko, Anna G Sorace, Kalina P Slavkova, Debra Patt, Boone W Goodgame, Sarah Avery, Thomas E Yankeelov
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-02-09.
https://doi.org/10.1158/1538-7445.SABCS21-P3-02-09
Published: 15 February 2022
View article titled, Abstract P3-02-09: Three timepoint pharmacokinetic modeling to incorporate within standard of care MRI breast exams
Journal Articles

Abstract 3138: Identification of therapy-sensitive tumor phenotypes using quantitative MRI habitats in a preclinical model of HER2+ breast cancer

Anum S. Kazerouni, David A. Hormuth, Tessa Davis, Meghan J. Bloom, John Virostko, Thomas E. Yankeelov, Anna G. Sorace
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 3138.
https://doi.org/10.1158/1538-7445.AM2021-3138
Published: 01 July 2021
View article titled, Abstract 3138: Identification of therapy-sensitive tumor phenotypes using quantitative MRI habitats in a preclinical model of HER2+ breast cancer
Journal Articles

Abstract 222: Towards patient-specific optimization of neoadjuvant treatment protocols for breast cancer based on image-based fluid dynamics

Chengyue Wu, David A. Hormuth, Federico Pineda, Gregory S. Karczmar, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 222.
https://doi.org/10.1158/1538-7445.AM2021-222
Published: 01 July 2021
View article titled, Abstract 222: Towards patient-specific optimization of neoadjuvant treatment protocols for breast cancer based on image-based fluid dynamics
Journal Articles

Abstract PS3-26: Characterizing errors in perfusion model parameters derived from retrospectively abbreviated quantitative DCE-MRI data

Kalina P Slavkova, Julie C DiCarlo, Anum K Syed, Chengyue Wu, John Virostko, Anna G Sorace, Thomas E Yankeelov
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS3-26.
https://doi.org/10.1158/1538-7445.SABCS20-PS3-26
Published: 15 February 2021
View article titled, Abstract PS3-26: Characterizing errors in perfusion model parameters derived from retrospectively abbreviated quantitative DCE-MRI data
Journal Articles

Abstract PS13-44: Identifying relevant parameters that characterize the early response to NAT in breast cancer patients using a novel personalized mechanistic model integrating in vitro and in vivo imaging data

Guillermo Lorenzo, Angela M. Jarrett, Christian T. Meyer, Darren R. Tyson, Vito Quaranta, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS13-44.
https://doi.org/10.1158/1538-7445.SABCS20-PS13-44
Published: 15 February 2021
View article titled, Abstract PS13-44: Identifying relevant parameters that characterize the early response to NAT in breast cancer patients using a novel personalized mechanistic model integrating <em>in vitro</em> and <em>in vivo</em> imaging data
Journal Articles

Abstract PS13-18: Predicting breast cancer response to neoadjuvant therapies using a mathematical model individualized with patient-specific magnetic resonance imaging data: Preliminary Results

Angela M Jarrett, David A. Hormuth, II, Anum K Syed, Chengyue Wu, John Virostko, Anna G Sorace, Julie C DiCarlo, Jeanne Kowalski, Debra Patt, Boone Goodgame, Sarah Avery, Thomas E Yankeelov
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS13-18.
https://doi.org/10.1158/1538-7445.SABCS20-PS13-18
Published: 15 February 2021
View article titled, Abstract PS13-18: Predicting breast cancer response to neoadjuvant therapies using a mathematical model individualized with patient-specific magnetic resonance imaging data: Preliminary Results
Journal Articles

Abstract 5483: An image-based mechanistic computational model for early prediction of organ-confined untreated prostate cancer growth

Guillermo Lorenzo, Thomas J. Hughes, Alessandro Reali, Hector Gomez, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5483.
https://doi.org/10.1158/1538-7445.AM2020-5483
Published: 15 August 2020
View article titled, Abstract 5483: An image-based mechanistic computational model for early prediction of organ-confined untreated prostate cancer growth
Journal Articles

Abstract 5487: A biologically-motivated mathematical model for forecasting chemoradiationresponse in high grade gliomas: Initial results

David Andrew Hormuth, Karine Al Feghali, Andrew M. Elliot, Caroline Chung, Thomas E. Yankeelov
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5487.
https://doi.org/10.1158/1538-7445.AM2020-5487
Published: 15 August 2020
View article titled, Abstract 5487: A biologically-motivated mathematical model for forecasting chemoradiationresponse in high grade gliomas: Initial results