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Thiruvengadam Arumugam
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Journal Articles

Abstract 4204: CDK4/6 inhibition mitigates chemotherapy-induced immunosuppression and enhances the efficacy of chemo- immunotherapy in small cell lung cancer models

Thiruvengadam Arumugam, Irene G. Muñoz, Alissa Poteete, Fahoa Zhang, Monique Nilsson, John S. Yi, Jessica A. Sorrentino, Andrew P. Beelen, John V. Heymach
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4204.
https://doi.org/10.1158/1538-7445.AM2022-4204
Published: 15 June 2022
View article titled, Abstract 4204: CDK4/6 inhibition mitigates chemotherapy-induced immunosuppression and enhances the efficacy of chemo- immunotherapy in small cell lung cancer models
Journal Articles

Abstract 2961: Targeting stromal-derived Dickkopf-3 (DKK3) for the treatment of pancreatic ductal adenocarcinoma (PDAC)

Liran Zhou, Hongmei Husted, Todd Moore, Mason Lu, Defeng Deng, Yan Liu, Vijaya Ramachandran, Thiruvengadam Arumugam, Baoan Ji, Huamin Wang, Jeffrey E. Lee, Craig D. Logsdon, Rosa F. Hwang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2961.
https://doi.org/10.1158/1538-7445.AM2017-2961
Published: 01 July 2017
View article titled, Abstract 2961: Targeting stromal-derived Dickkopf-3 (DKK3) for the treatment of pancreatic ductal adenocarcinoma (PDAC)
Journal Articles

Abstract B24: Targeting pancreatic ductal adenocarcinoma acidic microenvironment

Zobeida Cruz-Monserrate, Christina L. Roland, Defeng Deng, Thiruvengadam Arumugam, Anna Moshnikova, Oleg A. Andreev, Yana Reshetnyak, Craig D. Logsdon
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): B24.
https://doi.org/10.1158/1538-7445.PANCA2014-B24
Published: 30 June 2015
View article titled, Abstract B24: Targeting pancreatic ductal adenocarcinoma acidic microenvironment
Journal Articles

Abstract A112: Eradication of cancer stem-like cells in PDAC

Thiruvengadam Arumugam, Vijaya Ramachandran, Craig Logsdon
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): A112.
https://doi.org/10.1158/1538-7445.PANCA2014-A112
Published: 30 June 2015
View article titled, Abstract A112: Eradication of cancer stem-like cells in PDAC
Journal Articles

Cell Surface Lactate Receptor GPR81 Is Crucial for Cancer Cell Survival

Christina L. Roland, Thiruvengadam Arumugam, Defeng Deng, Shi He Liu, Bincy Philip, Sobeyda Gomez, William R. Burns, Vijaya Ramachandran, Huamin Wang, Zobeida Cruz-Monserrate, Craig D. Logsdon
Journal: Cancer Research
Cancer Res (2014) 74 (18): 5301–5310.
https://doi.org/10.1158/0008-5472.CAN-14-0319
Published: 14 September 2014
View article titled, Cell Surface Lactate Receptor GPR81 Is Crucial for Cancer Cell Survival
Open the PDF for Cell Surface Lactate Receptor GPR81 Is Crucial for Cancer Cell Survival in another window
Includes: Supplementary data
Journal Articles

Abstract B51: Gemcitabine-induced interleukin-8 expression is a surrogate marker for effects on pancreatic ductal adenocarcinoma cells and is associated with tumor microenvironment remodeling.

Thiruvengadam Arumugam, Takahiko Fujii, Huang Haojie, Rosa F. Hwang, Vijaya Ramachandran, Craig D. Logsdon
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): B51.
https://doi.org/10.1158/1538-7445.PANCA2012-B51
Published: 03 April 2014
View article titled, Abstract B51: Gemcitabine-induced interleukin-8 expression is a surrogate marker for effects on pancreatic ductal adenocarcinoma cells and is associated with tumor microenvironment remodeling.
Journal Articles

Abstract 3920: EphA2 transcription is regulated by activation of Ras / MEK2 / cytoplasmic ERK pathway in pancreatic cancer

Pavel A. Levin, Thiruvengadam Arumugam, David J. McConkey, Shrikanth Reddy, Craig D. Logsdon
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3920.
https://doi.org/10.1158/1538-7445.AM10-3920
Published: 15 April 2010
View article titled, Abstract 3920: EphA2 transcription is regulated by activation of Ras / MEK2 / cytoplasmic ERK pathway in pancreatic cancer
Journal Articles

Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer

Thiruvengadam Arumugam, Vijaya Ramachandran, Keith F. Fournier, Huamin Wang, Lauren Marquis, James L. Abbruzzese, Gary E. Gallick, Craig D. Logsdon, David J. McConkey, Woonyoung Choi
Journal: Cancer Research
Cancer Res (2009) 69 (14): 5820–5828.
https://doi.org/10.1158/0008-5472.CAN-08-2819
Published: 15 July 2009
View article titled, Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer
Open the PDF for Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Anterior Gradient 2 Is Expressed and Secreted during the Development of Pancreatic Cancer and Promotes Cancer Cell Survival

Vijaya Ramachandran, Thiruvengadam Arumugam, Huamin Wang, Craig D. Logsdon
Journal: Cancer Research
Cancer Res (2008) 68 (19): 7811–7818.
https://doi.org/10.1158/0008-5472.CAN-08-1320
Published: 30 September 2008
View article titled, Anterior Gradient 2 Is Expressed and Secreted during the Development of Pancreatic Cancer and Promotes Cancer Cell Survival
Open the PDF for Anterior Gradient 2 Is Expressed and Secreted during the Development of Pancreatic Cancer and Promotes Cancer Cell Survival in another window
Includes: Supplementary data
Journal Articles

Neutral liposome-coupled siRNA delivery against EphA2 receptor sensitizes gemcitabine resistant orthotopic pancreatic tumors in vivo.

Pavel Levin, Thiruvengadam Arumugam, Xue Pan, Pablo Vivas-Mejia, Anil Sood, Gabriel Lopez-Berestein, Craig Logsdon
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5728.
Published: 01 May 2008
View article titled, Neutral liposome-coupled siRNA delivery against EphA2 receptor sensitizes gemcitabine resistant orthotopic pancreatic tumors <em>in vivo</em>.
Journal Articles

Adrenomedullin promotes pancreatic tumors via the ADMR receptor in cancer, stromal and endothelial cells.

Vijaya Ramachandran, Thiruvengadam Arumugam, Rosa Hwang, Craig Logsdon
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5378.
Published: 01 May 2008
View article titled, Adrenomedullin promotes pancreatic tumors via the ADMR receptor in cancer, stromal and endothelial cells.
Journal Articles

TFF1 is expressed early in pancreatic cancer and increases cancer cell invasion and growth and migration of stellate cells within the tumor microenvironment.

Thiruvengadam Arumugam, Rosa Hwang, Todd Moore, Huamin Wang, William Brandt, Bruce Westley, Craig Logsdon
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3714.
Published: 01 May 2008
View article titled, TFF1 is expressed early in pancreatic cancer and increases cancer cell invasion and growth and migration of stellate cells within the tumor microenvironment.
Journal Articles

Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression

Rosa F. Hwang, Todd Moore, Thiruvengadam Arumugam, Vijaya Ramachandran, Keith D. Amos, Armando Rivera, Baoan Ji, Douglas B. Evans, Craig D. Logsdon
Journal: Cancer Research
Cancer Res (2008) 68 (3): 918–926.
https://doi.org/10.1158/0008-5472.CAN-07-5714
Published: 01 February 2008
View article titled, Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression
Open the PDF for Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression in another window
Journal Articles

Autocrine regulation of adrenomedullin on pancreatic cancer cells is mediated via ADMR

Vijaya Ramachandran, Thiruvengadam Arumugam, Diane Simeone, Craig Logsdon
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 3755.
Published: 01 May 2007
View article titled, Autocrine regulation of adrenomedullin on pancreatic cancer cells is mediated via ADMR
Journal Articles

NFkB reporter signaling distinguishes gemcitabine sensitive from resistant cell lines

Tameyoshi Yamamoto, Thiruvengadam Arumugam, Xue Pan, Craig Logsdon
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1190.
Published: 01 May 2007
View article titled, NFkB reporter signaling distinguishes gemcitabine sensitive from resistant cell lines
Journal Articles

TFF1 is over expressed early in pancreatic cancer in response to cancer-stromal interactions and stimulates cancer cell invasiveness.

Thiruvengadam Arumugam, Rosa Hwang, Moore Todd, Huamin Wang, Will Brandt, Bruce Westley, Craig Logsdon
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2794.
Published: 01 May 2007
View article titled, TFF1 is over expressed early in pancreatic cancer in response to cancer-stromal interactions and stimulates cancer cell invasiveness.
Journal Articles

Adrenomedullin Is Expressed in Pancreatic Cancer and Stimulates Cell Proliferation and Invasion in an Autocrine Manner via the Adrenomedullin Receptor, ADMR

Vijaya Ramachandran, Thiruvengadam Arumugam, Rosa F. Hwang, Joel K. Greenson, Diane M. Simeone, Craig D. Logsdon
Journal: Cancer Research
Cancer Res (2007) 67 (6): 2666–2675.
https://doi.org/10.1158/0008-5472.CAN-06-3362
Published: 15 March 2007
View article titled, Adrenomedullin Is Expressed in Pancreatic Cancer and Stimulates Cell Proliferation and Invasion in an Autocrine Manner via the Adrenomedullin Receptor, ADMR
Open the PDF for Adrenomedullin Is Expressed in Pancreatic Cancer and Stimulates Cell Proliferation and Invasion in an Autocrine Manner via the Adrenomedullin Receptor, ADMR in another window
Journal Articles

RAGE is alternatively spliced in pancreatic cancer and its secretory form stimulates cancer cell growth and invasion

Thiruvengadam Arumugam, Craig D. Logsdon
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 773–774.
Published: 15 April 2006
View article titled, RAGE is alternatively spliced in pancreatic cancer and its secretory form stimulates cancer cell growth and invasion
Journal Articles

Anterior gradient-2 is a novel growth and metastasis gene in pancreatic cancer

Vijaya Ramachandran, Thiruvengadam Arumugam, Craig Logsdon
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 715.
Published: 15 April 2006
View article titled, Anterior gradient-2 is a novel growth and metastasis gene in pancreatic cancer
Journal Articles

Pancreatic stellate cells promote malignant potential in pancreatic cancer

Keith D. Amos, Todd T. Moore, Thiruvengadam Arumugam, Craig D. Logsdon, Rosa F. Hwang
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 396.
Published: 15 April 2006
View article titled, Pancreatic stellate cells promote malignant potential in pancreatic cancer