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Thierry Dubois
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Journal Articles

Abstract P3-07-06: Comedications at Breast Cancer diagnosis impact overall survival: results from the ADRENALINE (Atlas for DRug and brEast caNcer survivAL INtEraction) study (n=235,368)

Elise Dumas, Beatriz Grandal, Paul Gougis, Sophie Houzard, Aurélien Latouche, Aullène Toussaint, Samar Alsafadi, Judith Abecassis, Lidia Delrieu, Thierry Dubois, Nadir Sella, Marc Espie, Bernard Asselain, Annabelle Ballesta, Benjamin Marande, Eric Daoud, Enora Laas, Amyn Kassara, Floriane Jochum, Elaine Del Nery, Elodie Anthony, Christine Le Bihan-Benjamin, Philippe-Jean Bousquet, Chloé-Agathe Azencott, Fabien Reyal, Anne-Sophie Hamy
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P3-07-06.
https://doi.org/10.1158/1538-7445.SABCS22-P3-07-06
Published: 01 March 2023
View article titled, Abstract P3-07-06: Comedications at Breast Cancer diagnosis impact overall survival: results from the ADRENALINE (Atlas for DRug and brEast caNcer survivAL INtEraction) study (n=235,368)
Journal Articles

Abstract 4031: PRMT1 regulates EGFR and Wnt signaling pathways and is a promising target for combinatorial treatment of breast cancer

Samyuktha Suresh, Solène Huard, Fariba Némati, Rayan Dakroub, André Nicolas, Didier Meseure, Didier Decaudin, Sergio Roman-Roman, Thierry Dubois
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4031.
https://doi.org/10.1158/1538-7445.AM2022-4031
Published: 15 June 2022
View article titled, Abstract 4031: PRMT1 regulates EGFR and Wnt signaling pathways and is a promising target for combinatorial treatment of breast cancer
Journal Articles

Abstract 4101: ADRENALINE, an atlas for drug and breast cancer survival interaction: Comedications at diagnosis and impact on breast cancer mortality of the French breast cancer cohort (n=235,375)

Elise Dumas, Beatriz Grandal, Lucie Laot, Eric Daoud, Lidia Delrieu, Marc Espié, Sophie Houzard, Christine Le Bihan-Benjamin, Philippe-Jean Bousquet, Elodie Anthony, Aurélien Latouche, Nadir Sella, Thierry Dubois, Annabelle Ballesta, Amyn Kassara, Elaine Del Nery, Benjamin Marande, Samar Alsafadi, Paul Gougis, Chloé-Agathe Azencott, Fabien Reyal, Anne-Sophie Hamy
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4101.
https://doi.org/10.1158/1538-7445.AM2022-4101
Published: 15 June 2022
View article titled, Abstract 4101: ADRENALINE, an atlas for drug and breast cancer survival interaction: Comedications at diagnosis and impact on breast cancer mortality of the French breast cancer cohort (n=235,375)
Journal Articles

Abstract 3348: Impact of comedications on pCR rates and relapse in breast cancer. Analysis of the Saint-Louis observational cohort

Anne-Sophie Hamy, Amyn Kassara, Hamid Hocini, Clementine Garin, Luis Teixeira, Caroline Cuvier, Paul Gougis, Elise Dumas, Fabien Reyal, Beatriz Grandal, Nadir Sella, Eric Daoud, Aurélien Latouche, Thierry Dubois, Annabelle Ballesta, Samar Alsafadi, Elaine Del Nery, Élodie Anthony, Benjamin Marande, Cedric de Bazelaire, Anne de Roquancourt, Catherine Michel, Sylvie Giacchetti, Marc Espie
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3348.
https://doi.org/10.1158/1538-7445.AM2022-3348
Published: 15 June 2022
View article titled, Abstract 3348: Impact of comedications on pCR rates and relapse in breast cancer. Analysis of the Saint-Louis observational cohort
Journal Articles

Abstract 5238: Characterization of the enzyme generating the cholesterol metabolite and tumor suppressor dendrogenin A in the breast and its deregulations in breast cancer

Marc Poirot, Emmanuel Noguer, Florence Dalenc, Regis Soules, Lisa Barrett, Arnaud Rives, Hye-Young Kim, Brigitta Sjödin, Camille Franchet, Pilippe Rochaix, Raphaelle Duprez-Paumier, Magali Lacroix-Triki, Thomas Filleron, Leonor Chaltiel, Louise Jones, Emanuala Gadaleta, Claude Chalala, Sergio Roman-Roman, Thierry Dubois, Ned A. Porter, Bengt Mannervik, Michel Record, Sandrine Silvente-Poirot
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5238.
https://doi.org/10.1158/1538-7445.AM2018-5238
Published: 01 July 2018
View article titled, Abstract 5238: Characterization of the enzyme generating the cholesterol metabolite and tumor suppressor dendrogenin A in the breast and its deregulations in breast cancer
Journal Articles

Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer

Bo Li, Triona Ni Chonghaile, Yue Fan, Stephen F. Madden, Rut Klinger, Aisling E. O'Connor, Louise Walsh, Gillian O'Hurley, Girish Mallya Udupi, Jesuchristopher Joseph, Finbarr Tarrant, Emer Conroy, Alexander Gaber, Suet-Feung Chin, Helen A. Bardwell, Elena Provenzano, John Crown, Thierry Dubois, Sabine Linn, Karin Jirstrom, Carlos Caldas, Darran P. O'Connor, William M. Gallagher
Journal: Cancer Research
Cancer Res (2017) 77 (14): 3834–3845.
https://doi.org/10.1158/0008-5472.CAN-16-2546
Published: 13 July 2017
View article titled, Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer
Open the PDF for Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 3809: Protein arginine methyltransferase 1 (PRMT1) is a candidate therapeutic target for breast cancers

David Silvestre, Amélie Brisson, Bérengère Marty-Prouvost, Mengliang Ye, Hélène Bonsang, Virginie Maire, Damarys Loew, David Gentien, Didier Meseure, Fabien Reyal, Gordon C. Tucker, Sergio Roman-Roman, Thierry Dubois
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3809.
https://doi.org/10.1158/1538-7445.AM2016-3809
Published: 15 July 2016
View article titled, Abstract 3809: Protein arginine methyltransferase 1 (PRMT1) is a candidate therapeutic target for breast cancers
Journal Articles

Abstract 41: The Wnt3a targetome in triple-negative breast cancer cell lines

Sylvie Maubant, Bruno Tesson, Virginie Maire, Mengliang Ye, Guillem Rigaill, David Gentien, Francisco Cruzalegui, Gordon C. Tucker, Sergio Roman-Roman, Thierry Dubois
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 41.
https://doi.org/10.1158/1538-7445.AM2015-41
Published: 01 August 2015
View article titled, Abstract 41: The Wnt3a targetome in triple-negative breast cancer cell lines
Journal Articles

Abstract 2764: The depletion of LRP5, unlike that of LRP6, promotes apoptosis in triple-negative breast cancer cells, making it an interesting therapeutic target

Sylvie Maubant, Virginie Maire, Bruno Tesson, Fariba Némati, David Gentien, Bérengère Marty-Prouvost, Stéphane Depil, Francisco Cruzalegui, Gordon Tucker, Sergio Roman-Roman, Thierry Dubois
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2764.
https://doi.org/10.1158/1538-7445.AM2014-2764
Published: 01 October 2014
View article titled, Abstract 2764: The depletion of LRP5, unlike that of LRP6, promotes apoptosis in triple-negative breast cancer cells, making it an interesting therapeutic target
Journal Articles

Abstract 1218: Development of comprehensive molecular portraits of lobular breast cancer within the RATHER (Rational Therapy for Breast Cancer) Consortium.

Justine K. Peeters, Ian Majewski, Leanne de Koning, Yue Fan, Finbarr Tarrant, Darran O'Connor, Jeroen Heijmans, Mireille Snel, Tesa Severson, Astrid Bosma, Magali Michaut, Lorenza Mittempergher, Suet-Feung Chin, Thierry Dubois, William Gallagher, Carlos Caldas, Rene Bernards, Iris Simon, RATHER Consortium
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1218.
https://doi.org/10.1158/1538-7445.AM2013-1218
Published: 15 April 2013
View article titled, Abstract 1218: Development of comprehensive molecular portraits of lobular breast cancer within the RATHER (Rational Therapy for Breast Cancer) Consortium.
Journal Articles

Abstract 4373: LRP5: a potential therapeutic target in triple-negative breast cancer.

Sylvie Maubant, Virginie Maire, Bruno Tesson, David Gentien, Bérengère Marty-Prouvost, Francisco Cruzalegui, Stéphane Depil, Gordon C. Tucker, Sergio Roman-Roman, Thierry Dubois
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4373.
https://doi.org/10.1158/1538-7445.AM2013-4373
Published: 15 April 2013
View article titled, Abstract 4373: LRP5: a potential therapeutic target in triple-negative breast cancer.
Journal Articles

Polo-like Kinase 1: A Potential Therapeutic Option in Combination with Conventional Chemotherapy for the Management of Patients with Triple-Negative Breast Cancer

Virginie Maire, Fariba Némati, Marion Richardson, Anne Vincent-Salomon, Bruno Tesson, Guillem Rigaill, Eléonore Gravier, Bérengère Marty-Prouvost, Leanne De Koning, Guillaume Lang, David Gentien, Aurélie Dumont, Emmanuel Barillot, Elisabetta Marangoni, Didier Decaudin, Sergio Roman-Roman, Alain Pierré, Francisco Cruzalegui, Stéphane Depil, Gordon C. Tucker, Thierry Dubois
Journal: Cancer Research
Cancer Res (2013) 73 (2): 813–823.
https://doi.org/10.1158/0008-5472.CAN-12-2633
Published: 16 January 2013
View article titled, Polo-like Kinase 1: A Potential Therapeutic Option in Combination with Conventional Chemotherapy for the Management of Patients with Triple-Negative Breast Cancer
Open the PDF for Polo-like Kinase 1: A Potential Therapeutic Option in Combination with Conventional Chemotherapy for the Management of Patients with Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Ploidy and Large-Scale Genomic Instability Consistently Identify Basal-like Breast Carcinomas with BRCA1/2 Inactivation

Tatiana Popova, Elodie Manié, Guillaume Rieunier, Virginie Caux-Moncoutier, Carole Tirapo, Thierry Dubois, Olivier Delattre, Brigitte Sigal-Zafrani, Marc Bollet, Michel Longy, Claude Houdayer, Xavier Sastre-Garau, Anne Vincent-Salomon, Dominique Stoppa-Lyonnet, Marc-Henri Stern
Journal: Cancer Research
Cancer Res (2012) 72 (21): 5454–5462.
https://doi.org/10.1158/0008-5472.CAN-12-1470
Published: 31 October 2012
View article titled, Ploidy and Large-Scale Genomic Instability Consistently Identify Basal-like Breast Carcinomas with <em>BRCA1/2</em> Inactivation
Open the PDF for Ploidy and Large-Scale Genomic Instability Consistently Identify Basal-like Breast Carcinomas with <em>BRCA1/2</em> Inactivation in another window
Includes: Supplementary data
Journal Articles

Abstract A13: A signaling pathway rationale for the design of combination therapies for cancer

Paola Vera-Licona, Andrei Zinovyev, Eric Bonnet, Inna Kupperstein, Olga Kel-Margoulis, Alexander Kel-Margoulis, Thierry Dubois, Gordon Tucker, Emmanuel Barillot
Journal: Cancer Research
Cancer Res (2012) 72 (13_Supplement): A1.
https://doi.org/10.1158/1538-7445.CSB12-A13
Published: 01 July 2012
View article titled, Abstract A13: A signaling pathway rationale for the design of combination therapies for cancer
Journal Articles

Abstract 3000: Molecular profiling of residual tumor cells after various chemotherapies shows distinct gene expression patterns in patient-derived breast cancer xenografts

David Gentien, Stéphane Depil, Pierre Gestraud, Charles Decraene, Gérôme Jules-Clement, Benoit Albaud, Anne Vincent-Salomon, Fabien Reyal, Aurélie Thuleau, Francisco Cruzalegui, Gordon C. Tucker, Thierry Dubois, Sergio Roman-Roman, Didier Decaudin, Elisabetta Marangoni
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3000.
https://doi.org/10.1158/1538-7445.AM2012-3000
Published: 15 April 2012
View article titled, Abstract 3000: Molecular profiling of residual tumor cells after various chemotherapies shows distinct gene expression patterns in patient-derived breast cancer xenografts
Journal Articles

Abstract 2938: Polo-like kinase 1: a potential therapeutic target for the management of patients with triple negative breast cancer

Virginie Maire, Fariba Némati, Bérengère Marty-Prouvost, Aurélie Dumont, Marion Richardson, Anne Vincent-Salomon, Guillaume Lang, Bruno Tesson, Guillem Rigaill, Emmanuel Barillot, Elisabetta Marangoni, Didier Decaudin, Sergio Roman-Roman, Alain Pierré, Francisco Cruzalegui, Stéphane Depil, Gordon C. Tucker, Thierry Dubois
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2938.
https://doi.org/10.1158/1538-7445.AM2012-2938
Published: 15 April 2012
View article titled, Abstract 2938: Polo-like kinase 1: a potential therapeutic target for the management of patients with triple negative breast cancer
Journal Articles

Abstract 5130: Integrative approaches for the identification of therapeutic targets in basal like breast cancer from multi-level molecular data

Bruno M. Tesson, Guillem Rigaill, Anne Vincent-Salomon, David Gentien, Sergio Roman-Roman, Alain Pierré, Francisco Cruzalegui, Stéphane Depil, Gordon Tucker, Thierry Dubois, Emmanuel Barillot
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5130.
https://doi.org/10.1158/1538-7445.AM2012-5130
Published: 15 April 2012
View article titled, Abstract 5130: Integrative approaches for the identification of therapeutic targets in basal like breast cancer from multi-level molecular data
Journal Articles

Abstract #2460: Statistical analysis of high density comparative genomic hybridization (CGH) arrays

Guillem Rigaill, Thierry Dubois, Stéphane Robin, Emmanuel Barillot
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2460.
Published: 01 May 2009
View article titled, Abstract #2460: Statistical analysis of high density comparative genomic hybridization (CGH) arrays
Journal Articles

An integrated image analysis tool for the systematic analysis of reverse phase protein array data

Minzi Ruan, Yiling Lu, Julia Wulfkuhle, Ginny Espina, Shenzhi Yu, Min Ma, Thierry Dubois, Chin-Rang Yang, Qinghua Yu, Emanuel Petricoin, Lance Liotta, Gordon Mills
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5119.
Published: 01 May 2008
View article titled, An integrated image analysis tool for the systematic analysis of reverse phase protein array data
Journal Articles

Deciphering the kinome in basal-like breast carcinoma for therapeutic usefulness

Berengere Marty, Fathia Djelti, Ingrid Lebigot, Anne Vincent-Salomon, Francisco Cruzalegui, Gordon Tucker, Xavier Sastre, Jean-Paul Thiery, John Hickman, Thierry Dubois
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2829.
Published: 01 May 2007
View article titled, Deciphering the kinome in basal-like breast carcinoma for therapeutic usefulness